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Eligo Bioscience Awarded $5 Million to Advance Breakthrough Genetic Medicine Platform for Immuno-Dermatology

Eligo Bioscience Awarded $5 Million to Advance Breakthrough Genetic Medicine Platform for Immuno-Dermatology

Cision Canada13-05-2025
Funding is part of the call for proposals "Innovations in Biotherapies and Bioproduction," coordinated by the Health Innovation Agency under France 2030 strategy, operated on behalf of the French government by Bpifrance
PARIS, May 13, 2025 /CNW/ -- Eligo Bioscience, a biotechnology company pioneering the development of novel genetic medicines, today announced it has secured a $5 million grant from the French government to accelerate the advancement and scaling up of Eligo's proprietary topical gene delivery platform, designed to enable local production of therapeutic biologics directly by skin-resident bacteria.
This grant follows recent key milestones for Eligo, including the publication of its microbiome base-editing platform in Nature, securing multiple foundational patents covering in situ editing of the skin microbiome, and successfully expanding its Series B funding round to $35 million. This latest non-dilutive financial support strengthens Eligo's capacity to rapidly advance its clinical pipeline.
Scaling up and advancing towards the clinic
Building on the development of its first-generation CRISPR-based topical therapeutic targeting moderate to severe acne vulgaris, Eligo will now optimize and scale up the bioproduction process of its innovative gene delivery vector ahead of later-stage clinical trials. In this endeavor, Eligo is partnering with Biose Industries, a globally recognized CDMO specializing in microbial fermentation. Biose's extensive GMP expertise in scaling complex microbial therapeutics will be instrumental in accelerating Eligo's progress toward clinical validation.
"This funding empowers us to establish a robust bioproduction process for our first-in-class topical microbiome-targeting gene-editing therapies, laying the groundwork for expanding into a wide range of immuno-dermatological indications," said Dr. Xavier Duportet, CEO and Co-Founder of Eligo Bioscience."It reinforces our ambition to deliver truly transformative therapeutic solutions, addressing critical medical challenges faced by millions of patients worldwide."
Expansion to immuno-dermatology targets
The skin microbiome plays a pivotal role in cutaneous immune regulation, and commensal bacteria residing within the hair follicle lie in immediate proximity to resident immune cells.
Eligo's unique in-situ delivery modality enables to perform in-situ genetic engineering of these commensal bacteria, turning them as localized bioreactors that can express high-potency biologics precisely where immune dysregulation occurs.
The new funding will support the exploration of multiple therapeutic payloads and the build-out of a diversified immuno-dermatology pipeline targeting chronic inflammatory and immune-mediated skin diseases with significant unmet need.
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Libman: No vacation from language law excesses in Quebec
Libman: No vacation from language law excesses in Quebec

Montreal Gazette

time4 hours ago

  • Montreal Gazette

Libman: No vacation from language law excesses in Quebec

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World Insights: With Gaza kids wasting away, Israeli blockade sparks global condemnation
World Insights: With Gaza kids wasting away, Israeli blockade sparks global condemnation

Canada News.Net

timea day ago

  • Canada News.Net

World Insights: With Gaza kids wasting away, Israeli blockade sparks global condemnation

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MOUNTING GLOBAL PRESSURE ON ISRAEL As the humanitarian nightmare continues, global outrage is reaching a boiling point. Macron stepped up diplomatic pressure on Israel with his Friday statement, following public condemnation earlier this week by France and several other European countries over Israel's blockade of aid and the killing of hundreds of Palestinians trying to reach food. He said in a post on social media platform X that he will "make the solemn announcement" of France's recognition of Palestine's statehood in September's UN General Assembly. "The urgency today is to end the war in Gaza and to provide aid to the civilian population." "There must be an immediate ceasefire, the release of all hostages, and massive humanitarian aid to the people of Gaza," he wrote, noting "there is no alternative." As the biggest Western power to recognize Palestine, France could pave the way for other countries to follow, the AP said in a Friday report. So far, over 140 countries recognize a Palestinian state, including more than a dozen in Europe like Slovenia, Norway and Spain, while Israel urged countries to hold off on recognition until the decades-old conflict is resolved. "We strongly condemn President Macron's decision," Israeli Prime Minister Benjamin Netanyahu said in a statement. "Such a move rewards terror and risks creating another Iranian proxy, just as Gaza became. A Palestinian state in these conditions would be a launch pad to annihilate Israel -- not to live in peace beside it." The Palestinian Authority welcomed it. "We express our thanks and appreciation" to Macron, said Hussein al-Sheikh, vice president of the Palestine Liberation Organization. "This position reflects France's commitment to international law and its support for the Palestinian people's rights to self-determination." 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"This reckless decision only serves Hamas propaganda and sets back peace," U.S. Secretary of State Marco Rubio wrote in a post on X, soon after the country cut short Gaza ceasefire talks in Qatar, accusing Hamas of lacking "good faith." U.S. CUTS SHORT PEACE TALKS The United States is cutting short Gaza ceasefire talks and pulling its negotiating team out of Qatar for consultations, after Hamas's latest response "shows a lack of desire" to reach a truce, U.S. Special Envoy to the Middle East Steve Witkoff said Thursday. "While the mediators have made a great effort, Hamas does not appear to be coordinated or acting in good faith," Witkoff said in a statement. "We will now consider alternative options to bring the hostages home and try to create a more stable environment for the people of Gaza," without disclosing any details on what those alternatives might be. 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dynaCERT's emissions-cutting tech now deployed at a major port in France
dynaCERT's emissions-cutting tech now deployed at a major port in France

The Market Online

timea day ago

  • The Market Online

dynaCERT's emissions-cutting tech now deployed at a major port in France

dynaCERT Inc. is taking its HydraGEN™ technology global and this time, it's landed in one of Europe's major shipping corridors. The company just announced its emissions-cutting tech is now deployed at the Port of Rochefort-Tonnay in France, a serious move into industrial-scale decarbonization at one of the continent's key logistics hubs. Lyndsay Malchuk recently sat down with Kevin Unrath, the Chief Operating Officer of dynaCERT, a company rewriting the playbook for clean tech in heavy industry. He's here to talk about the rollout, what it means for adoption, and where they're going next. The following is a transcription of the above video, and The Market Online has edited it for clarity Lyndsay: Kevin, let's get right into it. HydraGEN™ is now live at the major French port. How big of a statement is this deployment for the industrial side of your business? Kevin: Basically, this deployment in the port over in France is a major milestone, especially for our France distributor, as it marks his first intro in the off-road applications and into the industrial environment. Over there in France we already have proven success in a lot of transportation fleets across the whole country and across a wide range of truck manufacturers. Now, by integrating HydraGEN™ into a crane operation, we are demonstrating broader potential also in that country, not only across the world and globally, and not only in Canada, North America, or maybe let's say our European hub here in Germany. It shows that reducing emissions and saving fuel is possible even in demanding industrial settings as this harbor. Lyndsay: Kevin, let's be honest here. The emission space is full of buzzwords and broken promises. We all know that. So what makes this rollout real? What kind of impact is it actually delivering in the field? Kevin: What makes it real basically is that this rollout is tangibly on the scientific approach. So what we always try to do is follow a scientific approach, which also means going into pre studies, going into trials with our customers, and also this implementation performed competitive gas emission measurements on the crane operations with and without HydraGEN™ before the final installation. And it allowed us to quantify the greenhouse gas reduction and fuel savings under real operating conditions already before we got into the final contracts and the installation, which is installed now. It's not a pilot anymore. That's important. Now, this is really a working measurable solution after a first pilot. Lyndsay: We all know too that ports are notorious for emission zones. Is this just the beginning of a broader play into European or global logistics? What's the vision beyond this port? Kevin: I think we have to differentiate the answer a little bit in two or three categories. So the first topic is definitely on the harbor side. It's our first public step to go in there. But as we see, it's already generating momentum. Also the celebration during the installation and everything is already showing high interest out of the harbor market to us. And we are already in several other port discussions, and we are looking forward to seeing maybe further follow up projects after this. Beyond this, we are seeing increased traction all across Europe. If we talk about logistics for sure, we talk about harbors, but for us also very important on that intermodal part of logistics. We also look on, for example, transport logistics on streets. So that means commercial vehicles and things like this, but also into intralogistic topics in harbors and other topics like forklifts and things like this. This where we are, we are seeing supported by our strong presence at the Bauma, which you also shared, and we had a joint video at our evening event. And even at the transport logistics only four to five weeks ago here in Munich, we had a real strong presence and we really see a lot of discussions coming out of this and a high interest in the market. So concluding your questions. Yeah, we are going deeper into these topics. We are more looking on the European market and also this is shown by the fact that I'm not only COO of the company internationally. I also, alongside this campaign, did take over the responsibility for the GMBH in Europe as Managing Director and taking care of the European business there. Lyndsay: Your tech is very innovative, and we all know with that type of tech, it usually faces some pushback from operators who don't want any downtime. So let's talk about that. What are you hearing on the ground from the people actually running the hardware? Kevin: The feedback from the operators is very positive. Let's say basically like this. The system integrates smoothly into your running applications. That's the most important point for them. So they do not want to have long down times for installation or getting to know the product. So this is why smoothly integration is very, very important for them. And users already see fuel savings from the beginning. So there is no time needed like a few months or something to realize the full fuel savings. It's basically an installation of two to three hours. It's an aftermarket product and you directly, if you switch on the truck or the harbor crane, again, you will see the fuel savings. There's also growing anticipation for upcoming carbon credit programs for sure, as we are working on the carbon credit side with VERRA also, and which will make HydraGEN™ installations even more financially attractive to all of the customers by having really the fuel saving, the emission reduction and the carbon credit generation. This adds another layer of value for the customers for sure, but also important for us, we are still looking on the environmental and economic effect of all our customers. Lyndsay: I want to dive a little bit deeper into the investor lens of things. I mean, how should we be thinking about this deployment? Is this a one-off win or the first domino in a bigger commercial wave? Kevin: No, for us looking onto Europe in general, but also looking on France in specific. In France alone, we have had already equipped a large number of different trucks across the country, so different brands, and we have proved from that the technology works. So this for us is now very, very important in the further, let's say succession on the market over here in Europe, which we are striving for. We have already proven that technology works across different engines, different fuels, including things like HVO also testing over here in Germany at some customers. So we see a broad range of success and this is exactly what we are trying and striving for further success. dynaCERT is now trading under the ticker DYA on the TSX. To learn more about how they're turning real-world logistics into a clean tech revolution, visit This is no longer about future potential. They're already plugged in and scaling up Company shares last traded at $0.155 Join the discussion: Find out what everybody's saying about this stock on the dynaCERT investor discussion forum, and check out the rest of Stockhouse's stock forums and message boards. The material provided in this article is for information only and should not be treated as investment advice. For full disclaimer information, please click here.

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