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Book Review: John Green is obsessed with tuberculosis. He makes a strong case that we should be, too

Book Review: John Green is obsessed with tuberculosis. He makes a strong case that we should be, too

Yahoo17-03-2025
So you read 'The Fault in Our Stars' or watched John Green on YouTube, and, if you're like me, you probably thought, 'I would read or watch anything this mind produced for public consumption.' Even if it's a 200-page nonfiction thesis on tuberculosis arguing why it should be Public Enemy No. 1 and on its way to eradication.
Because, in true John Green fashion, there's a footnote on the copyright page explaining the reasoning behind the font choice for his newest book, 'Everything is Tuberculosis.' (Spoiler: The reason for the font is tuberculosis. Everything is.)
Early on, Green establishes that the tuberculosis is the top killer of humans among infectious diseases — a longstanding status quo only briefly disrupted by COVID-19. The slow-moving TB infected over 8 million people in one year and killed about 1.25 million, according to a recent World Health Organization report.
Yet, as Green shows throughout the book, TB is curable and even preventable.
The text seamlessly moves through related topics, from TB's effects on history and fashion to the socioeconomic inequities that perpetuate the disease, and even the romanticization of an illness that, for a period, was associated with soulful poets and delicate feminine beauty.
But this synopsis will seem bone-dry compared to the actual text, because the real magic of Green's writing is the deeply considerate, human touch that goes into every word. He uses the stories of real people to turn overwhelming problems into something personal and understandable. 'We can do and be so much for each other — but only when we see one another in our full humanity,' Green writes.
'Everything is Tuberculosis' is reflective and earnest, with a few black-and-white pictures to illustrate a point or put a face to a name. Little nuggets of personalization consistently bring us back to our shared humanity, even in footnotes.
When considering 'patient noncompliance,' Green discloses his own diagnoses and wrestling with taking prescriptions. This compared with patients in Sierra Leone who, unlike Green, often struggle to get to the clinic to obtain their medication, or can't afford enough food to take it without getting sick. On the other hand, some of their struggles are the same, side effects from pills and stigma around illnesses being some of the most common reasons patients might diverge from their prescribed course of medication, regardless of access.
As one might expect from Green, the book is weirdly touching and super quotable. 'Everything is Tuberculosis' is rich with callbacks that help underscore ideas, wit and humor that foster learning even alongside more somber bits.
Green offers many reasons why he became obsessed with TB, but none brought tears to my eyes so unexpectedly like the stunningly apt metaphor comparing writing to the pool game 'Marco Polo.' The explanation references TB activist Shreya Tripathi, who had to sue the Indian government to get the medication that would have saved her if it hadn't taken so long to get ahold of it.
Despite the death and harsh realities, it is a hopeful book overall.
Green takes stock of the history, looking at the vicious and virtuous cycles that led humankind to where we are now, posing a challenge and a question rolled into one: Which type of cycle will we foster?
___
AP book reviews: https://apnews.com/hub/book-reviews
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Small Investment, Big Returns: Why This NIH Center Matters
Small Investment, Big Returns: Why This NIH Center Matters

Forbes

timean hour ago

  • Forbes

Small Investment, Big Returns: Why This NIH Center Matters

UNITED STATES - MAY 10: Activists hold signs during rally outside the National Institutes of Health in Bethesda, Md., on Saturday, May 10, 2025. (Bill Clark/CQ-Roll Call, Inc via Getty Images) CQ-Roll Call, Inc via Getty Images 25 years ago, I had a life-changing experience. I got the biggest break in my career. My application to do a PhD at the University of California, Berkeley was accepted, and I was offered funding support through a National Institutes of Health (NIH) program called the Fogarty AIDS International Training Program. I had little money those days, and without NIH funding and a welcoming professor who cared deeply about global health, I could have never left India for higher education in the United States. Today, I chair a department of global and public health at a leading Canadian university. The life-changing opportunities I had as a Fogarty trainee at Berkeley allow me to pay it forward by training the next generation of global health leaders. I was not the only scholar to benefit from Fogarty funding - nearly 8,500 individuals from 132 countries have trained through Fogarty programs since 1989, and many have become leaders in their countries. Several have led groudbreaking research projects, and led inspiring programs and institutions. Soumya Swaminathan is a great example. After her Fogarty training in the United States, she went on to become a leading HIV and TB researcher, become the Director-General of the Indian Council of Medical Research, and subsequently the first Chief Scientist of the World Health Organization. 'My Fogarty fellowship gave me an opportunity to get exposed to advanced immunological techniques and meet leading experts at a critical stage of my career. It helped spark new ideas and initiate collaboration with international experts which may not have happened otherwise,' she said. Another shining example is Glenda Gray, who was the first female President of the South African Medical Research Council. 'Becoming a Fogarty Fellow catalysed my career as a clinician scientist, and marked the beginning of my research trajectory," she said. "It enabled me to make contributions to HIV vaccine research and development, as well as research in the area of preventing mother to child transmission. The interventions we developed have led to the control of paediatric HIV and improvements in treatment that have reduced HIV-related mortality in children,' she explained. Gray is currently Director of the Infectious Disease and Oncology Research Institute, University of the Witwatersrand. The Fogarty International Center (FIC) has also benefitted US scientists and institutions. In FY24, Fogarty funded 440 U.S. grantees from 122 U.S. institutions in 39 states. Research conducted in Global South countries have led to improved treatments for health challenges of importance to Americans. 'The training programs supported by the FIC over the past 40 years have been unparalleled in their reach and impact around the world,' said Arthur Reingold, Emeritus professor at Berkeley School of Public Health, who has trained hundreds of scholars through his Fogarty grants. 'They have, through their support of highly talented biomedical scientists from scores of low and middle income countries, dramatically improved research and educational capacity globally, as well as markedly enhanced high impact collaborative research on AIDS, tuberculosis, malaria, and diverse other communicable and non communicable diseases. The benefits resulting from the enhanced research capabilities of scientists supported by the FIC have accrued to people living everywhere, including in the United States,' he elaborated. Lucian Davis, an Associate Professor at Yale Medicine and the Yale School of Public Health, has also used the Fogarty program to train dozens of American and African scholars. 'Fogarty enables us to train the world's brightest minds to tackle America's leading health priorities—a high-impact, low-cost investment that keeps us connected to the world,' he said. And guess what, the entire annual budget of the FIC is a merely 0.2% of the total NIH budget - a drop in the bucket. Despite this tiny investment, the FIC has had a spectacular national and global footprint and impact, by any metric. Today, it greatly saddens me to see defunding of US science agencies, including NIH, and it's devastating impact on US academic institutions and scientists. Several American scientists have either reached out to me to explore options in Canada, or have applied for faculty positions at my university. Scores of American scientists are seeking to flee the country (and become "science refugees"). It boggles my mind that US politicians are allowing this brain drain to happen under their watch. America's economic strength, in part, comes from the nation's immense scientific firepower. I am especially distressed to learn that the FIC is once again on the chopping block, with the entire $95 million budget FIC budget set to become zero in 2026. How exactly is cutting such an impactful program supposed to make America great? Even as the world deals with massive crises like pandemics, conflicts, climate change, and widening economic inequities, all of which require truly, global cooperation and coordination, it seems like politicians are choosing narrow self-interests, nationalism, and isolationism. This strategy is not likely to succeed. Why? We've all witnessed how interconnected the world is during the Covid-19 pandemic. Viruses that emerge in far away places will find us, regardless of who we are or where we happen to live. Every outbreak is merely one long-haul flight away. Smoke from wildfires will travel thousands of miles to darken our skies and choke our lungs. NEW YORK, NEW YORK - JUNE 7: Smoky haze from wildfires in Canada diminishes the visibility of the Chrysler Building on June 7, 2023 in New York City. (Photo by David) Getty Images There is no way to protect just one nation or one region when threats are trans-national. Our fates are undisputably intertwined with that of other countries and peoples. There is nothing 'woke' about looking out for each other in an interdependent world. And that is why America must stay engaged in global health and multi-laterialism. And that is why American lawmakers must work to protect a national treasure like the Fogarty International Center. If an investment is yielding spectacular returns, no smart business person would dream of killing it. So, why defund the FIC and the NIH? If I was a US lawmaker, that is the question I would be asking myself. I take some hope from the fact that the Senate Appropriations Committee recently rejected the Trump administration's proposed funding cuts to the NIH. But the road ahead is long and hard. I hope good sense will prevail and the powers that be will find a way to save America's phenomenal scientific enterprise. Science matters for America's health. It matters for health of the whole world.

Who needs the gym? Longevity expert shares the only 6 exercises you need after 40, 50 and 60 to build strength
Who needs the gym? Longevity expert shares the only 6 exercises you need after 40, 50 and 60 to build strength

Yahoo

time4 hours ago

  • Yahoo

Who needs the gym? Longevity expert shares the only 6 exercises you need after 40, 50 and 60 to build strength

When you buy through links on our articles, Future and its syndication partners may earn a commission. As you age, finding exercises that work for your body is crucial to staying strong and active while maintaining both your physical and mental well-being. According to renowned physician and longevity expert, Dr. Peter Attia, just a handful of exercises can 'redefine how you age.' Shared to the YouTube channel Health Reveal and completely accessible to everyone, these six essential exercises could 'transform your body, boost your strength and help you live a longer, healthier life.' Dr. Attia's goal with each move is to build endurance, increase mobility and resilience, and slow down the effects of aging. Here they are, and why you should try them. What are the exercises? As we age, muscle mass decreases and strength declines, leaving us more susceptible to injury and chronic health conditions. That means we need to start training smarter to benefit from the most efficient and effective strength exercises out there. According to Dr. Attia, these are six exercises you shouldn't skip. 1. Dead hang The dead hang tests upper-body endurance and grip strength, just from hanging off a bar. Grip strength has been associated with longevity and overall health, and it's one of the longevity fitness tests touted by Arnold Schwarzenegger via his fitness app. A strong grip also helps make everyday activities easier, like carrying groceries. According to Dr. Attia, men aged 40 years or older should aim for two minutes, while women of the same age should aim for 90 seconds, and this scales depending on age and sex. I personally find even 30 seconds a serious struggle, so try to build up slowly and don't get too hung up on the numbers to begin with. Here's how to do the dead hang step-by-step. 2. 90-degree air squat Squats strengthen your lower body, improve mobility and help prevent falls as you age. The humble bodyweight squat targets muscle groups associated with balance and stability, like your glutes, quads, hips, hamstrings and calves. If you're around 40 years old, try to manage two minutes of squats as a minimum. You're aiming to reach 90 degrees with your legs so that your thighs reach parallel to the floor, and as you get stronger, add reps or weight as needed. Here's how to squat step-by-step. 3. Cardio VO2 max — how efficiently your body uses oxygen during exercise — is crucial for overall cardio fitness and lifespan. A higher VO2 max is strongly associated with longevity, lowering your risk of chronic health conditions associated with the heart and lungs, and also helps improve endurance. Learning how to measure your VO2 max can give you a baseline to work from. Dr. Attia suggests movement like running, cycling, swimming, rowing, or walking, but if you do decide running is your forte, Attia says you should aim to reach the top 50-75% for your sex and age group. This might take some research, but he recommends seven to eight-minute miles if you can, runners. This is just a guideline, and remember to build slowly according to your fitness level. 4. Farmer's walk The farmer's walk targets grip, core and leg strength, and builds functional fitness, stability and endurance. You'll also improve balance and coordination by carrying heavy weights across a set distance, and you can single or double load depending on what equipment you have available. Aim for two minutes while maintaining your breath, form and posture. Add weight and duration as you get stronger, and try to practice this exercise consistently so that you can measure improvements over time. Dr. Attia says men should aim to carry their bodyweight for two minutes (half the total weight in each hand), while women should aim for a minimum of 75% of their bodyweight. This is just a guideline, so if you need to carry more or less to start with, do. Here's how to do the farmer's carry step-by-step. 5. Vertical jump Vertical jumps test for overall leg strength, explosive power and agility as you age. It's a great way to measure overall fitness and power, translating to tasks like standing from a seated position and climbing. You're looking to drive upward as you jump and land softly with a knee bend to reduce the pressure on your joints. Try to measure and increase your jump height as you get better; at least 20 inches is a great starting point, according to the advice in the video. 6. Wall sit Wall sits are great for testing your quad, glute and core strength, and build stamina and stability under tension. The sit is known as an isometric exercise because muscles are held under tension without moving, which is a low-impact way to strengthen the muscles and joints responsible for preventing falls and maintaining posture. This translates to everyday activities like walking or standing for long periods. Aim for two minutes and work on increasing the duration of the hold. Consistent practice will help you maintain stamina as you get older. Here's how to do a wall sit step-by-step. Bottom line Backed by science, these six longevity movements are recommended by a longevity expert to help improve life quality and slow down the impact of aging on the body. Whatever your age, you can stay feeling strong and full of energy, while slowing down muscle atrophy and bone density loss. So if anyone tells you that nature will continue to do its thing, don't listen. You can maintain bone density and lean muscle mass while building a strong and mobile body, reducing the likelihood of chronic conditions and sedentary-related injuries at the same time. Follow Tom's Guide on Google News to get our up-to-date news, how-tos, and reviews in your feeds. Make sure to click the Follow button. More from Tom's Guide Forget running and swimming — study finds this sport adds 10 years to your life No, not sit-ups — strength and conditioning coach says 'this is the best abs exercise you're probably not doing' Forget the gym — this 10-minute mobility routine boosts your flexibility and improves your posture without equipment

Weight loss support before IVF could boost pregnancy chances – and reduce the need for treatment
Weight loss support before IVF could boost pregnancy chances – and reduce the need for treatment

Yahoo

time5 hours ago

  • Yahoo

Weight loss support before IVF could boost pregnancy chances – and reduce the need for treatment

Around one in five women of childbearing age are living with [obesity], defined by the World Health Organization as having a body mass index (BMI) over 30 kg/m². Compared with women in the healthy BMI range (18.5–24.9 kg/m²), those living with obesity are three times more likely to experience fertility problems and nearly twice as likely to have a miscarriage. Many turn to in vitro fertilisation (IVF) in the hope of having a baby. Women with obesity who are planning a pregnancy are already advised that losing weight can improve their chances of conceiving. Our research suggests that structured weight loss support may also improve outcomes for those seeking IVF. Our study analysed data from 12 international trials involving 1,921 women living with obesity, all planning IVF. It compared those offered a weight loss programme before IVF with those receiving standard care, which typically does not include such support. Women who took part in a weight loss programme had a 21% higher chance of becoming pregnant overall – whether naturally or through IVF. The biggest difference was in natural conceptions: the likelihood of getting pregnant without IVF rose by 47%, meaning some women avoided fertility treatment altogether. However, despite these higher pregnancy rates and no increase in miscarriage risk, there was no clear evidence of an effect on live birth rates. This may be because many of the included studies didn't track live birth outcomes – even though this is the result that matters most to patients. IVF access paradox In the UK, publicly funded IVF is restricted to women with a BMI under 30. Similar weight-based eligibility rules exist in many other countries. These policies disproportionately affect women from more deprived backgrounds and some ethnic groups, who are more likely to be living with obesity. The paradox is clear: women with obesity are more likely to need IVF, but less likely to be eligible for it. Some can afford private weight loss programmes to meet the BMI requirement. Others resort to unproven or unsafe methods to lose weight quickly, risking their health in order to access fertility care. Our research findings suggest that offering structured weight loss programmes to women with obesity who are otherwise ineligible for IVF could help more women become pregnant – and in some cases avoid IVF altogether. This approach could also make fertility treatment more equitable. Since the cost of weight loss support is relatively low compared with IVF, including it in the treatment pathway might offer better value for healthcare providers. Weight loss options before IVF The most effective non-surgical option for significant weight loss is a class of medications called GLP-1 receptor agonists – such as Wegovy or Mounjaro – which have been shown to lead to substantial weight reduction. However, these drugs should not be used during pregnancy, while trying to conceive, or while breastfeeding, as there's little safety data in humans – and animal studies suggest potential harm to foetal development. Anyone who becomes pregnant while taking GLP-1 drugs should stop immediately and consult a healthcare professional. For women planning to conceive soon, there are other safe and effective options, including structured support groups and low-energy diet programmes. The problem is that such services are not offered as part of standard IVF care. While some NHS weight management programmes exist, access is limited, waiting lists can be long, and most are aimed at people with obesity-related health conditions rather than those seeking fertility treatment. In many other countries, insurance coverage for weight loss support is similarly patchy, meaning these services must often be funded privately – a cost that can put them out of reach for those who could benefit most. The message from this research is clear: targeted, supportive weight loss programmes before IVF don't just improve pregnancy chances – they could also reduce the need for IVF, promote fairer access to fertility treatment, and save healthcare resources. The challenge now is making sure they're available to everyone who needs them, not just those who can afford to pay. This article is republished from The Conversation under a Creative Commons license. Read the original article. The authors do not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and have disclosed no relevant affiliations beyond their academic appointment.

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