logo
NOBS Toothpaste Tablets: What Dentists Say About Its Main Ingredient

NOBS Toothpaste Tablets: What Dentists Say About Its Main Ingredient

CNET5 days ago
The NOBS (No Bad Stuff) toothpaste tablets are going viral thanks to their main ingredient of nano-hydroxyapatite, a fluoride-free alternative. As health concerns around fluoride and its presence in public drinking water continue to swirl, nano-hydroxyapatite toothpastes are becoming increasingly popular. You've likely seen them on store shelves or in ads from companies like Boka and Davids, marketed as fluoride-free alternatives for your toothbrush that claim to whiten teeth, repair enamel and prevent cavities.
"As ingredient labels shift toward cleaner, fluoride-free formulas, one compound is taking center stage in modern oral care: nano-hydroxyapatite," Dr. Pia Lieb, DDS, cosmetic dentist and clinical assistant professor emerita at NYU College of Dentistry, explains. According to dentists, if you're considering replacing your fluoride toothpaste with a nano-hydroxyapatite alternative like the now-viral NOBS, you should know the following potential benefits and side effects.
What is nano-hydroxyapatite?
"Nano-hydroxyapatite is a synthetic calcium phosphate compound that's used in some oral care products, including toothpastes," explains Dr. Ada Cooper, consumer advisor and spokesperson for the American Dental Association, says. "[It] has a structure that is similar to hydroxyapatite found in enamel, and nHAP gets incorporated into the tooth structure preferentially in demineralized areas."
Nano-hydroxyapatite is also abbreviated as n-HA and n-HAp.
Dr. Royce Lai of King Village Dental adds that this is technically a two-part question, since "hydroxyapatite has been around for decades and has been studied for at least 20 years." Newer and less studied, nano-hydroxyapatite is a version of hydroxyapatite with small, rod-shaped particles.
"Hydroxyapatite is natural. It is a type of calcium that makes up bones and teeth," says Lai. "Nano-hydroxyapatite relates to the particle size. These are between 20 and 80 nanometers and are much smaller than the hydroxyapatite tubules that are a part of your teeth."
According to Dr. Daniela Eversgerd, a cosmetic dentist and the founder of Allure Dental, nano-hydroxyapatite was developed by NASA in the 1970s for astronauts dealing with bone and enamel loss during long periods of space travel. Since the early 1990s, it has been approved for oral care products in Japan.
Nano-hydroxyapatite toothpaste benefits
"Nano-hydroxyapatite doesn't just protect your teeth -- it helps rebuild them," says Dr. Catrise Austin, a cosmetic dentist, author of Gum Health Made Simple and host of the Let's Talk Smiles podcast. She lists the following as potential nano-hydroxyapatite benefits:
Enamel remineralization
Tooth sensitivity relief
Reduced bacterial adhesion
Whitening and gloss enhancement
"n-HA can actually fill microscopic cracks and help reverse or arrest early cavities," adds dentist Dr. Sandip Sachar.
Austin cites a 2019 study that found a 10% hydroxyapatite toothpaste is equivalent or non-inferior to fluoride toothpaste for preventing and remineralizing dental cavities (or caries) in children.
When it comes to teeth sensitivity, Lai cites a 2014 study concluding that 15% nano-hydroxyapatite helped sensitive teeth. "The particle size could get into space and work better than larger particles in micro-hydroxyapatite or fluoride," he explains. "The conclusion was that nano-hydroxyapatite could significantly reduce tooth sensitivity to hot and cold in two to four weeks of use."
Referencing an 18-month 2023 clinical trial finding that a 10% n-HAp toothpaste protected adult teeth from new cavities as well as a standard 1,450-ppm fluoride paste, Dr. Christopher Tolmie, DDS, MBA, of PDS Health, states, "By patching enamel and calming swollen gums, nano-hydroxyapatite may cut off a hidden spark of chronic inflammation linked to heart disease and diabetes."
Since nano-hydroxyapatite toothpastes are fluoride free, Dr. Yenile Y. Pinto, DDS, functional and biomimetic dentist and founder of Deering Dental, adds, "It's also been shown to reduce sensitivity and strengthen the enamel surface without the risk of fluorosis." Fluorosis occurs when you get too much fluoride as a child, causing white or brown spots on the teeth. The CDC reports that fluorosis typically doesn't affect tooth function and isn't painful.
A 2020 systematic review of 32 studies concluded that "Nano-HA is a relatively novel material with outstanding physical, chemical, mechanical and biological properties that makes it suitable for multiple interventions. It outperformed most of the classic materials used in implantology and surgery, but it should be further investigated for bone engineering and caries prevention therapy."
HengleinA 2023 comprehensive review found that, while more long-term studies are needed to establish the safety of regular use, "Nanohydroxyapatite is a promising revolutionary material in the prevention of early carious lesion mainly due to a greater source of free calcium."
Ultimately, providing a 2021 review and 2022 scoping review, Cooper concludes, "Although there is some evidence that alternative ingredients, such as [nano] hydroxyapatite, prevent tooth decay by acting as a remineralizing or anti-cavity agent, the studies are preliminary. The only anti-cavity agent recognized by the Food and Drug Administration in its over-the-counter monograph is fluoride, a naturally occurring chemical."
Cooper adds that all toothpastes with the ADA Seal of Acceptance contain fluoride. The administration specifically recommends brushing your teeth twice a day with fluoride toothpaste and regularly visiting your dentist.
Nano-hydroxyapatite toothpaste side effects
"According to a [2021] narrative review from Odontology, the official journal of the Society of the Nippon Dental University, so far, there have been no reports of adverse dental or systemic effects of HAP-containing toothpastes because HAP has an excellent biocompatibility," states Cooper.
According to Austin, the concern with nano-hydroxyapatite is that, because it's made of nanoparticles, some worry about how much might get absorbed into the body if regularly swallowed. "The European Commission's Scientific Committee raised concerns due to the lack of long-term safety data on ingestion, particularly in children," she says. This has led to temporary nano-hydroxyapatite restrictions (not a full-on banning) in Europe.
The European Scientific Committee deems nHA safe in toothpaste up to 29.5% and up to 10% in mouthwash, per Tolmie. However, he states, "Regulators still bar it from breath-spray products to avoid lung exposure, so stick to pastes and rinses."
Key concerns around nano-hydroxyapatite, according to Lieb, are:
Potential ingestion and systemic absorption, especially in nano form
Lack of long-term studies in humans on the cumulative effects
Unknown impact of inhalation from aerosol products (not toothpaste)
In terms of systemic absorption, Sachar specifies, "Because nano-hydroxyapatite particles are similar in composition to bone mineral, there has been some theoretical concern that if absorbed systemically, they could potentially contribute to unwanted calcifications in soft tissues (like blood vessels or kidneys)." However, she states that this is speculative and not supported by any current clinical evidence.Is nano-hydroxyapatite toothpaste only effective at 10%?
"Most clinical formulations of nHA range from 5%-15%, with 10% emerging as the benchmark concentration in several Japanese and European studies," answers Lieb. "This concentration has demonstrated reliable enamel restoration while maintaining product stability and usability."
However, she states that newer formulations are experimenting with lower concentrations and enhanced delivery systems (such as encapsulation or synergistic minerals), which may improve efficacy at reduced levels. "The effectiveness isn't just about percentage, it's also about particle quality and how it's delivered to the tooth surface," she explains.
Tolmie adds, "Effective repair starts as low as 5% and plateaus around 10-15%. Several studies show that 5% n-HAp can mend enamel dings, divots and dents in the teeth, with benefits leveling off somewhere between 10% and 15%. One review even noted that 5% sometimes beats 10% because fewer particles clump, making them easier to slip into enamel defects; hence, most US brands sit comfortably in the 5-10% sweet spot."
Should people replace fluoride toothpaste with nano-hydroxyapatite?
Eversgerd states that it all depends on each person's oral health needs. "Fluoride remains the gold standard for cavity prevention, supported by decades of large-scale, randomized controlled trials," she explains. "However, for patients seeking a fluoride alternative -- whether due to sensitivity, allergies, personal preferences or a desire for a biomimetic approach -- nano-hydroxyapatite provides a scientifically supported option."
According to the Academy of Biomimetic Dentistry, a biomimetic approach is one in which damaged teeth are restored using materials mimicking natural teeth in function, strength and appearance.
For high-risk patients, Eversgerd recommends fluoride, while she may recommend n-Ha to low-risk or fluoride-averse individuals.
Austin seconds this, but adds that she also recommends fluoride toothpaste to children with poor brushing habits or communities with limited dental access. "nHA is a great option, but it's not a one-size-fits-all replacement for fluoride -- yet," Austin says.
Lieb explains that nHA may also be a compelling alternative for patients with aesthetic concerns, such as whitening-induced sensitivity, and individuals in preventive care regimens post-restorative treatment.
Pinto agrees that it depends on the person, stating, "For most of my patients, especially those with low to moderate cavity risk, nano-hydroxyapatite is an excellent option; gentler on the mouth, less drying and effective at rebuilding early damage. For people with high cavity risk, fluoride might still be the best choice, at least short term. For my high-risk patients, I often recommend a combo toothpaste that includes both ingredients when appropriate." Ultimately, if a patient isn't high risk and has health or safety concerns about fluoride, she thinks hydroxyapatite is a great option.
When asked if there's a reason people should choose n-HAp over other anti-cavity toothpastes, Tolmie answers, "No, as long as patients are brushing their teeth with an anti-cavity toothpaste. There are differences in the way an n-HAp toothpaste and a fluoride toothpaste work to prevent decay, and some n-HAp toothpastes may feel smoother on the teeth. But anti-cavity toothpastes as a whole accomplish the same task. Do I wash a car with tap water or bottled water? We know that both of them get the job done."
What's most important, according to Tolmie, is that patients ensure they're not swallowing toothpaste.
What does the American Dental Association think? Cooper states that the ADA recommends brushing teeth twice daily for two minutes with fluoride toothpaste, as the naturally occurring mineral has been proven to remineralize weakened enamel and reverse early signs of tooth decay.
"Additionally, the fluoride you take in from drinking water and other beverages continues to provide a topical benefit because it becomes part of your saliva, constantly bathing the teeth and helping to rebuild weakened tooth enamel," Cooper further explains. "The best scientific evidence has shown that adding fluoride to community water supplies is safe and effective. This is backed by decades of research and recognized by more than 100 health organizations."
GoodboyDoes nano-hydroxyapatite toothpaste work?
All of the dentists we consulted agree that nano-hydroxyapatite toothpaste works, but in the right context and with the right product. It's also not a miracle cure and should not replace your entire oral care routine, dentist's recommendations or regular appointments. Plus, Eversgerd adds that more long-term, large-scale trials are needed to fully validate whether it's equal to fluoride in preventing cavities.
When asked if it's effective, Austin says, "Yes -- particularly for enamel remineralization and sensitivity. In my practice, I've seen patients who switched to nHA toothpaste experience noticeable improvements in comfort, plaque control and surface smoothness. But like any product, it works best when paired with consistent brushing, flossing and professional cleanings."
Pinto agrees and has also seen the results firsthand. "It helps remineralize enamel, soothe sensitivity and support a healthier oral microbiome, especially when paired with a good routine (good home hygiene, healthy diet, hydration and nasal breathing)," she explains, noting that it's not a miracle cure, but does offer many benefits.
On behalf of the ADA, Cooper echoes Eversgerd's earlier statement: "The use of nano-hydroxyapatite (nHAP) in over-the-counter products is growing and some evidence shows that nHAP may contribute to remineralization, but the evidence is fairly new and often ambiguous, especially regarding clinical indications. "
Do experts recommend nano-hydroxyapatite toothpaste?
All of the experts we consulted do recommend nano-hydroxyapatite toothpaste, but only for certain patients. After all, according to Austin, "Nearly half of US adults over 30 have some form of gum disease, and you can't out-toothpaste a bad hygiene routine." Brushing your teeth regularly, flossing and regularly visiting your dentist are still essential, no matter what toothpaste you use.
Though Lieb recommends nHA toothpaste for adult patients experiencing post-whitening sensitivity or early enamel erosion, low-caries risk individuals seeking natural alternatives and adults undergoing cosmetic dental work who want to protect their investment with gentle, remineralizing care, she doesn't recommend nano-hydroxyapatite for children with deciduous dentition.
"In my professional opinion, fluoride remains the safest and most effective option for all patients under 14," says Lieb. "Its protective effect during the development of permanent dentition is unmatched, and its caries-prevention record is well established."
Sachar states that she often recommends it for "patients seeking fluoride-free options, those with mild tooth sensitivity and for children at risk of swallowing fluoride toothpaste." However, she advises that patients with moderate to high cavity risk not fully abandon fluoride.
Again, it's important to note that the "ADA recommends that adults brush their teeth twice daily with fluoride toothpaste for at least two minutes each time, or as directed by a licensed dentist," according to Cooper. This is because the proposed benefits of nHAP are fairly new and ambiguous.
Getty Images
The bottom line
Though more research is needed, the dentists we consulted explained that nano-hydroxyapatite toothpaste can be an effective alternative to fluoride -- but only in the right context. The ADA doesn't recommend it. It's also not a miracle cure or a replacement for brushing regularly, flossing and professional dental appointments.
If you're considering nano-hydroxyapatite toothpaste, consult your dentist first before making the switch. They know your teeth best and will be able to help you find the best toothpaste for your smile.
Orange background

Try Our AI Features

Explore what Daily8 AI can do for you:

Comments

No comments yet...

Related Articles

Yes, You Should Brush Your Teeth For 2 Minutes, Twice A Day. Here's Why.
Yes, You Should Brush Your Teeth For 2 Minutes, Twice A Day. Here's Why.

Forbes

timean hour ago

  • Forbes

Yes, You Should Brush Your Teeth For 2 Minutes, Twice A Day. Here's Why.

Maintaining good oral hygiene practices is key to keeping your teeth and gums healthy—and spending two minutes brushing twice a day is a crucial part of any routine. This may seem like a simple mandate, but there are several factors to keep in mind when you're brushing for optimal results: Technique, toothpaste, pacing and more will make a difference. The ultimate goal of brushing your teeth is to remove bacteria, which can otherwise build up to cause decay and disease. '[For] oral disease, whether that's cavities or whether that's gum disease, reducing the amount of bacterial load in the mouth is a critical piece of that prevention measure,' says Jennifer Cullen, clinical assistant professor at the University of Michigan School of Dentistry. We spoke to three dental experts to learn the best tips and tricks for keeping your teeth sparkling ... More clean. Illustration: Forbes / Photos: Retailers To help you make the most of your two-minute toothbrushing sessions—and learn why we should brush at this cadence in the first place—I spoke to three dental experts to get their advice: Mark S. Wolff, DDS, PhD, Morton Amsterdam dean and professor of the division of restorative dentistry at the University of Pennsylvania; Jennifer Cullen, clinical assistant professor at the University of Michigan School of Dentistry, and director of the division of dental hygiene; and Matthew Messina, DDS, associate professor, clinical and clinic director at the Ohio State University College of Dentistry, and ADA spokesperson. These experts shared their insights on how to brush most effectively, and why brushing teeth is important, to help you stay motivated. Here are the tips and techniques they recommend. Multiple clinical studies show that brushing for two minutes is key to removing plaque so you can keep your teeth and gums healthy. 'There's clinical studies that have shown two minutes of brushing to be highly effective in reducing [tooth] decay,' says Dr. Wolff. A key reason for the two-minute mandate is so you can actually reach the surface of every tooth in the mouth with your brush, and tackle all of the plaque on your teeth. Cullen explained that there are multiple layers of plaque on teeth, and that the longer you brush, the better you can get to the bottom-most, stickiest layers. The experts I spoke with maintained that thoroughly brushing the surface of every tooth takes time: You want to make sure you get the cheek and tongue surface and the back and front of each one. Wolff advises softly placing the bristles right at the gumline to start brushing. How can you ensure you're getting each tooth? 'Brush methodically, not randomly,' says Wolff. Approaching each quadrant of the mouth in 30-second intervals can help you hit all the areas of your mouth, too. Some of the best electric toothbrushes we've tested, like the Oral-B iO Deep Clean + Protect, our pick for the best smart electric toothbrush, and the Philips Sonicare 9900 Prestige, our pick for best splurge electric toothbrush, not only buzz at 30-second intervals to move you along but also have apps that track your brushing to show you any spots you're missing. Let Fluoride Do Its Job The other crucial reason to brush for two minutes twice a day is to let the fluoride in toothpaste take effect to help prevent tooth decay. Cullen notes that hygienists and dentists recommend that people use some sort of fluoridated toothpaste, and that 'there is evidence for the benefits of that increased duration with respect to fluoride delivery.' The experts I spoke to said that fluoride is key to protecting tooth enamel, and that longer exposure to fluoride makes it harder for bacteria to build back up on the tooth. 'It's actually making the enamel less soluble to acids,' says Wolff. Many of the best electric toothbrushes have timers to track your brushing. Some, like the Oral-B iO Deep Clean + Protect, display time clearly on the brush's LED interface and offer cartoon faces (ranging from a frown to starry-eyed smile) to indicate where you stand with your time goal. This brush also works with an app to help you track time, and uses a buzzer in 30-second increments to cue you to move around your mouth. Other brushes use an automatic shutoff feature, or similar buzzing notifications, to let you know when you've reached your full two minutes. Timers And Apps There are multiple ways to time your brushing. Cullen suggests a sand timer for kids or patients with special needs. Dr. Messina recommends using a timer on your phone. He also notes there are apps that are especially helpful for kids to guide them to brush around their mouth over the course of two minutes. Break It Up By Quadrant To break up the two minutes, you can also count for 30 seconds while brushing each quadrant of your mouth, if you don't have an electric toothbrush that does this automatically. This can help keep track of time while making sure you're getting to every tooth. Sing A Song Both Cullen and Messina suggest one way to track your time is to either sing or play a favorite song that lasts around two minutes. This can help gamify your brushing—and make it more enjoyable, a technique that can be especially helpful for kids. Be Gentle Though it's important to be thorough while brushing, experts advise against brushing too hard. 'You don't want to wear the teeth away by scrubbing like this is a floor,' says Wolff. Brushing too hard can actually damage your teeth and gums. To avoid that, opt for a brush with soft bristles. Many electric toothbrushes also have pressure sensors to indicate if you're brushing too aggressively, or if you're hitting the sweet spot. In our electric toothbrush tests, we preferred the easy-to-see sensor on the Oral-B iO Deep Clean + Protect, which uses a light around the neck of the toothbrush to flash green, white or red to indicate pressure. Other brushes can have pressure sensors that will buzz or light up to tell you to ease up. Don't Forget To Floss Brushing is just one key component of a great oral hygiene routine; it can't act alone. Flossing is crucial to reach every surface of the tooth to remove food and debris. 'Brushing itself only reaches 60% of your tooth surfaces,' says Cullen. 'Everywhere a tooth touches another tooth, that toothbrush can't get to.' She recommends floss or an adaptive aid to help get into those hard-to-reach spaces. We've also tested the best water flossers at Forbes Vetted, and these devices can help reach in between teeth to clear debris. The Waterpik Aquarius Water Flosser won as best water flosser overall in our tests. Water flossers may be especially useful for people with orthodontia or those who have difficulty using traditional dental floss. Consider The Swish, And The Social Brush All the experts I spoke to recommended brushing at least twice a day—but what if you want, or need, to brush more frequently? In general, that's fine, and some people may need to brush more frequently due to medical conditions or orthodontia. Wolff advises being mindful of not brushing too hard, however. 'There's nothing wrong with too much or too frequent brushing, as long as you do it gently and you don't wear away the gums [or] damage the tooth with a hard toothbrush,' he says. He also warned of compensating with frequency versus technique. 'Doing it three times a day badly does not make you less likely to get cavities or less likely to have gum disease,' he says. If you don't have access to a sink or brush after every meal, there are still easy things you can do to help keep your mouth cleaner. Cullen and Messina both advise swishing your mouth with water after eating to neutralize the pH of the mouth (when the environment of the mouth is more acidic, it becomes more hospitable to cavity-causing bacteria). Messina also recommends what he calls a 'social brush,' or a quicker brush to clear the mouth of food—for example, after eating a pungent meal like a hamburger with onions— that's less thorough than your twice-daily toothbrushing geared toward deeper cleaning and hitting every surface of the tooth. Remember That Every Patient Has Different Needs Though brushing your teeth for two minutes twice a day is the standard, every patient has different needs; some people may need to brush more frequently or require assistance with brushing. Cullen spoke to how a 10-year-old who isn't snacking frequently or drinking sweet drinks could brush just twice a day, while someone with Parkinson's disease may need to brush more frequently and with assistance. Sometimes electric toothbrushes can help people brush more effectively, but other assistive devices, like a universal cuff, can also help with holding a toothbrush independently. Cullen also said that caregivers may need to give patients breaks or adjust the location for brushing. 'If you're a caregiver, maybe you're doing it at the kitchen table,' she says. 'Maybe you're able to brush for 60 seconds and that person needs a break.' Check in with your hygienist, dentist and care team for the most relevant advice for your needs. Some Brushing Is Better Than None Building new habits like brushing your teeth for two minutes twice a day takes time, and starting a new routine can be intimidating. Messina notes that some patients can feel overwhelmed by the guilt of not brushing enough, and encourages people to do the best they can. Brushing isn't all or nothing; even if you can't reach the full two minutes, Messina says it's still helpful to brush in the first place, no matter how long the duration. 'I know if you start small, that you'll realize how much better it feels and then you'll do more and more,' he says. And remember, brushing is key to overall health. 'It seems like such a small thing to brush your teeth twice a day, but I think people should be encouraged that they're really making a big impact on their overall health when they do that small thing,' says Cullen.

20 Hurdles For Healthcare Tech Startups In Scaling Solutions
20 Hurdles For Healthcare Tech Startups In Scaling Solutions

Forbes

timean hour ago

  • Forbes

20 Hurdles For Healthcare Tech Startups In Scaling Solutions

A healthcare startup may launch with a bold and innovative idea, but turning that idea into a scalable solution that works across hospitals and complex health systems is rarely straightforward. From integrating with legacy infrastructure to navigating strict compliance requirements and diverse stakeholder priorities, even the most agile teams can struggle to scale effectively. Left unaddressed, these challenges can stall adoption, drain internal resources and limit a product's long-term impact. Below, members of Forbes Technology Council highlight some of the most common hurdles healthcare startups must be ready for and share their expertise on breaking into and succeeding in this challenging sector. 1. Finding Client Champions To scale solutions within a health system or payer organization, you need to engage a team of internal champions who can understand, justify and prioritize your platform. Organizations evaluate dozens if not hundreds of companies each year. Champions help articulate your value, often leveraging their professional credibility to advocate for it. Finding and 'winning' them is essential to scaling. - Graham Gardner, Kyruus Health 2. Navigating Integration Requirements Across Hospital Systems One of the biggest hurdles is navigating the complexities of integration requirements across different hospital systems. Healthcare startups frequently underestimate the time and resources needed for integrations. Success requires building flexible APIs from day one and having dedicated integration specialists who understand healthcare IT infrastructure, not just general software development. - Ted Kail, Cority Forbes Technology Council is an invitation-only community for world-class CIOs, CTOs and technology executives. Do I qualify? 3. Gaining Traction In A Risk-Averse Environment Most healthcare organizations are risk-averse and don't want to be early adopters. They look for proven, well-established companies and products, making it difficult for healthcare startups to get traction, even when they have clearly better solutions. Partnering and delivering real value to that first set of clients is critical in scaling early on. - John Bou, Modio Health 4. Integrating With Insurance Systems Health insurance companies amplify the interoperability challenge by adding another layer of complex, often siloed, data and systems that healthcare tech startups must integrate with. This makes the negotiation and implementation of business associate and HIPAA agreements more complicated, given the data types, security requirements and shared liabilities that arise from integrating with both providers and payers. - Ajai Paul, Affirm Inc. 5. Understanding The Complex Stakeholder Ecosystem Healthcare startups often make the mistake of viewing the U.S. healthcare system with a 'singular' point of view. It is an integrated ecosystem where each stakeholder is affected by the others, which means multiple interests must be aligned when adopting new technologies. - Raghav Ramabadran, Intelligine Technologies 6. Building Custom Integrations For Each Customer Healthcare startups' challenges include integrating with electronic health record systems, which is not a 'plug and play' process. Each hospital or system has its own highly customized version of an EHR, with unique workflows, data fields and security protocols. This lack of standardization means startups must build a new integration for nearly every customer. - Chris Ciabarra, Athena Security Inc. 7. Developing Strong Governance From The Outset Healthcare startups often wait to build full product depth until after landing their first client, but healthcare's high-risk, structured environment demands strong governance from day one. Change control, release management and a deep understanding of current operations, especially when replacing legacy systems, are essential before customizing. Building depth late risks delays and failure! - Trisha Swift, Mula Integrative Health & Wellness 8. Maintaining HIPAA Compliance With Digital Content One challenge healthcare startups face when scaling tech is managing digital content while staying HIPAA-compliant. Hospitals need more than stock photos and shared drives—they expect secure, role-based access to branded visuals that convey authenticity and protect patient privacy. Without a digital asset management strategy, startups risk falling short on compliance, credibility and growth. - Andrew Fingerman, PhotoShelter 9. Ensuring Consistent Performance And Compliance Across Disparate Systems Healthcare startups often struggle to scale because hospital environments vary widely in terms of infrastructure, workflows and data systems. Without a unified data architecture, real-time metrics, and built-in security and governance, it's hard to ensure consistent performance—or meet privacy requirements like HIPAA and business associate agreements governing protected health information. - Dave Albano, Diliko 10. Working Within Complex Pricing And Claims Rules One of the challenges is the integration of new tech into strict hospital billing and compliance processes. Hospitals have complex pricing and claims rules, and startups must work within these rules. They can't disrupt revenue or patient data safety. Doing this right builds trust and helps a solution scale faster. - Abhishek Sinha, Accenture 11. Processing Both Structured And Unstructured Health Data Integrating structured data (EHRs; lab results) and unstructured data (clinical notes; imaging; video) can be a major challenge. Healthcare startups must ensure their tech can process both, all while adapting to varying data and privacy standards across systems, which further complicates scaling and interoperability. Fortunately, generative AI is making this easier to do. - David Talby, John Snow Labs 12. Balancing Accuracy And Transparency With Scalability The healthcare and life sciences sector faces rigorous accuracy and transparency requirements that cannot be sacrificed and must be built into products from the start. Balancing this with scalability—which is really code for 'solving problems you don't have yet'—is a constant challenge—especially for startups, which often place a key focus on agility and speed. - Martin Snyder, Certara 13. Maintaining A Consistent, Accurate Record Of Core Assets One key challenge healthcare startups face when scaling tech solutions across systems is the inability to maintain a consistent and accurate record of core assets—such as patients, providers and devices—due to the absence of a robust master data management strategy. This causes data fragmentation, which in turn hinders decision-making, innovation and seamless integration across platforms. - Somnath Banerjee 14. Keeping Up With A Range Of Regional Norms And Laws Key challenges include a wide range of compliance requirements, regulations, cultural norms, and data privacy and region-specific laws—making a one-size-fits-all solution impractical, even within a single organization. Startups often rely on business rules engines that lack user friendliness. Agentic AI offers a more adaptable and intuitive alternative. - Koushik Sundar, Citibank 15. Working Within Legacy Hospital Systems One major challenge healthcare startups face when scaling tech solutions is integration with legacy hospital systems. Many hospitals rely on outdated EHRs or siloed IT infrastructure, making interoperability difficult. Startups must ensure compliance, data security and seamless integration to gain trust and adoption at scale. - Srikanth Bellamkonda 16. Clearly Demonstrating ROI And Pathways To Reimbursement Healthcare startups often struggle to clearly demonstrate a return on investment and secure reimbursement pathways. Without established billing codes or tangible cost-savings data, hospitals hesitate to allocate budget. Startups must invest heavily in economic validation, health economics and outcomes research, ensuring payers and finance teams see sustainable revenue models before adoption. - Manav Kapoor, Amazon 17. Creating An Internal COE Establishing an internal center of excellence with deep industry experience in scaling healthcare systems is vital, but costly. A key challenge lies in selecting vendors that align with the company's DNA. Bridging the gap between emerging tech and the unique demands of healthcare requires thoughtful planning and a nuanced understanding of both innovation and patient-centric outcomes. - Hari Sonnenahalli, NTT Data Business Solutions 18. Overcoming Resistance To New Tech I've regularly observed the challenges clinical sites face when adopting new technologies. There is often reluctance or resistance to change; staffing shortages further exacerbate these issues. A more effective approach may be to 'mirror' site-level data. This would allow AI-driven platforms to build a harmonized system that enables forward progress without disrupting existing workflows. - Rachel Tam, Bristol Myers Squibb 19. Accounting For Integration Issues When Building Solutions The biggest hurdle to overcome when scaling tech solutions across hospitals or healthcare systems is not technical; rather, it is integration—into provider workflows, clinical practice guidelines, financial models and revenue cycle management programs. Unless the issues around integration are considered and covered when building the solution, scaling will not occur. The landscape is littered with misaligned HealthTech startups. - Mark Francis, Electronic Caregiver 20. Completing Vendor Risk Documentation Post-ransomware, hospitals demand extensive vendor risk audits with hundreds of security controls, SOC 2/HITRUST docs, and custom BAAs. Completing these lengthy questionnaires stretches sales cycles to 18 to 24 months, burning cash and pulling engineers from product work to compliance, blocking scale. - Mohit Menghnani, Twilio

Anne Burrell died by suicide, medical examiner finds
Anne Burrell died by suicide, medical examiner finds

CNN

timean hour ago

  • CNN

Anne Burrell died by suicide, medical examiner finds

EDITOR'S NOTE: Help is available if you or someone you know is struggling with suicidal thoughts or mental health the US: Call or text 988, the Suicide & Crisis The International Association for Suicide Prevention and Befrienders Worldwide have contact information for crisis centers around the world. Popular Food Network star and celebrity chef Anne Burrell's death has been ruled a suicide, according to authorities. The Office of the Chief Medical Examiner in New York City confirmed to CNN on Thursday that Burrell died by suicide and that her cause of death is acute intoxication due to the combined effects of diphenhydramine, ethanol, cetirizine and amphetamine. Burrell, a chef and beloved fixture on the Food Network, died last month at her home in New York. She was 55. A spokesperson for the New York Police Department told CNN at the time that officers responded to Burrell's home in Brooklyn, where they 'observed a 55-year-old female unconscious and unresponsive.' 'EMS responded and pronounced the female deceased at the scene,' police said. In a statement provided by the Food Network at the time, Burrell's family said that her 'light radiated far beyond those she knew, touching millions across the world.' 'Though she is no longer with us, her warmth, spirit, and boundless love remain eternal,' their statement added. A Food Network spokesperson added: 'Anne was a remarkable person and culinary talent – teaching, competing and always sharing the importance of food in her life and the joy that a delicious meal can bring. Our thoughts are with Anne's family, friends and fans during this time of tremendous loss.' Burrell had a storied history as a television personality and chef but was best known as one of the Food Network's most popular stars, appearing in several of the network's series including 'Worst Cooks in America,' 'Iron Chef America,' 'Chef Wanted with Anne Burell' and 'The Best Thing I Ever Ate,' among many others, over the years. This is a developing story.

DOWNLOAD THE APP

Get Started Now: Download the App

Ready to dive into a world of global content with local flavor? Download Daily8 app today from your preferred app store and start exploring.
app-storeplay-store