Recursion to present clinical data from ongoing Phase 1b/2 trial of REC-4881
The company states: 'Recursion will present preliminary data during the 2025 Digestive Disease Week meeting from its ongoing Phase 1b/2 clinical trial, TUPELO, which is evaluating the safety and preliminary activity of REC-4881 for the treatment of familial adenomatous polyposis (FAP). The data will be presented as a late-breaking oral presentation during the Research Forum session on Hereditary GI cancer syndromes on Sunday, May 4, 2025 in San Diego. Currently, there are no FDA-approved therapies for FAP, a rare hereditary autosomal dominant colorectal cancer predisposition syndrome, affecting approximately 50,000 people in the US, France, Germany, Italy, Spain, and the UK. REC-4881 has been granted Fast Track and Orphan Drug designation by the U.S. Food and Drug Administration as well as Orphan Drug designation by the European Commission.'
Stay Ahead of the Market:
Discover outperforming stocks and invest smarter with Top Smart Score Stocks.
Filter, analyze, and streamline your search for investment opportunities using Tipranks' Stock Screener.
Hashtags
Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles
Business Upturn
3 hours ago
- Business Upturn
OneSource Specialty Pharma shares jump 3% after USFDA grants VAI classification for its Bangalore facility
By Aman Shukla Published on June 10, 2025, 09:22 IST Shares of OneSource Specialty Pharma Ltd jumped 3% in morning trade on June 10 after the company announced that its flagship facility in Bangalore received a 'Voluntary Action Indicated' (VAI) classification from the U.S. Food and Drug Administration (USFDA). As of 9:21 AM, the shares were trading 3.61% higter at Rs 2,002.70. The classification follows a routine USFDA inspection conducted from March 20 to March 28, 2025. At the end of the inspection, the agency issued a Form 483 with four observations. The company responded with a comprehensive corrective action plan. After reviewing the response, the USFDA designated the outcome as VAI, indicating that while issues were noted, they were not serious enough to trigger regulatory or enforcement action. The VAI status also confirms that the inspection is now officially closed. The company did not disclose the specific details of the observations, but emphasized that the facility remains integral to its core manufacturing and development operations. A VAI classification is generally seen as a positive regulatory outcome, especially compared to more severe classifications like 'Official Action Indicated' (OAI). Investors reacted favorably to the news, pushing the stock higher. Disclaimer: The information provided is for informational purposes only and should not be considered financial or investment advice. Stock market investments are subject to market risks. Always conduct your own research or consult a financial advisor before making investment decisions. Author or Business Upturn is not liable for any losses arising from the use of this information. Aman Shukla is a post-graduate in mass communication . A media enthusiast who has a strong hold on communication ,content writing and copy writing. Aman is currently working as journalist at
Yahoo
11 hours ago
- Yahoo
20 million eggs recalled from Walmart, Safeway other stores in WA, other states
A salmonella outbreak has caused the recall of 1.7 million dozen eggs and has sickened 79 people in seven states. Four people in Washington have been reported sick, and the U.S. Food and Drug Administration continues to track the outbreak. There have been no deaths. The recall was issued June 6 for 20 million eggs distributed to Walmart, Safeway, chains owned by Kroger and various other independent and chain supermarkets around the country. The Centers for Disease Control is recommending that people throw the eggs away. Hilmar, California's August Egg Co., a division of Gemperle Enterprises, produced the eggs and issued the recall last week. 'August Egg Company is not selling fresh shell eggs at this time,' the company-written, FDA-posted recall notice said. 'Our firm has voluntarily been diverting eggs to an egg-breaking plant for over 30 days, which pasteurizes the eggs and kills any potential foodborne pathogens.' Packaging for the recalled eggs will have plant code P-6562 or CA5330 with the Julian Dates between 32 to 126. The eggs that went to Walmart stores had sell-by dates from March 4 through June 19. Other retailers got eggs with 'sell by dates' from March 4 through June 4. The recall section of Walmart's website say the egg recall involves its stores in two dozen states, including Washington. The FDA's recall list includes California, Washington, Nevada, Arizona, Wyoming, New Mexico, Nebraska, Indiana and Illinois. Here are specific brands to look for: ▪ Marketside (a Walmart store brand): Organic Large Cage Free Brown Eggs in cartons of 12 and 18; Large Cage Free Brown Eggs in cartons of 12 and 18. ▪ First Street (a Smart & Final house brand): Cage Free Large Brown loose eggs. ▪ Clover: Organic Large Brown Eggs, one dozen. ▪ Nulaid: One dozen Medium Brown Cage Free, one dozen Jumbo Brown Cage Free. ▪ O Organics: Cage Free Large Brown, six eggs; and Large Brown, 12 and 18 eggs. This brand will be found at Safeway and other Albertson's-owned stores. ▪ Raley's (store brand): Large Cage Free Brown, 12 eggs: Organic Large Cage Free Brown, 12 and 18 eggs. ▪ Simple Truth: Cage Free Large Brown and Medium Brown 18 eggs. This brand will be found at Food 4 Less, Ralphs and other Kroger-owned chains. ▪ Sun Harvest: Organic Large Cage Free Brown Eggs in cartons of 12 and 18. ▪ Sunnyside: Organic Large Cage Free Brown Eggs in cartons of 12 and 18; and Large Cage Free Brown Eggs in cartons of 12 and 18. An outbreak update from the Centers for Disease Control and Prevention says 79 people have been sickened in this outbreak with 21 hospitalizations. Most of those have been in California, with four in Washington. The remaining 10 break down as Nevada (four); Arizona (three); Nebraska and New Jersey (two each); and Kentucky (one). Salmonella outbreaks tend to be under-counted because most people recover without medical attention. The CDC estimates about 1.35 million people in the United States will get salmonella each year. Of that number, 26,400 will be hospitalized, usually driven to the hospital by bloody diarrhea, and 420 will die. Usually, salmonella means a few days of diarrhea, vomiting, fever and stomachaches. The Mayo Clinic notes that salmonella symptoms include: Nausea and/or vomiting Abdominal cramps Diarrhea and/or blood in the stool Fever Chills Headache If you have any of the recalled eggs listed above, return them to the store for a refund or throw them deep into the garbage. If you have any questions about the recalls, call August Farms at 800-710-2554, 9 a.m. to 5 p.m. daily, Pacific time.
Yahoo
11 hours ago
- Yahoo
Over 19,000 Cases of Dr Pepper Have Been Recalled for Containing Sugar in Cans Marked ‘Zero Sugar'
Over 19,000 cases of Dr Pepper Zero Sugar were recalled after cans were found to contain full-sugar soda, posing health risks for those avoiding sugar The mislabeled cans, produced in Florida, were distributed in FL, GA and SC, with a "best by" date of Feb. 16, 2026 (Product Code: XXXXRS05165) In a separate recall, 1.7 million eggs were pulled due to salmonella; both recalls encourage refunds or safe disposal of affected productsOver 19,000 cases of Dr Pepper Zero Sugar are being recalled after the cans were found to contain full-sugar soda, the U.S. Food and Drug Administration announced. The voluntary recall, initiated May 23, affects 12-pack and 24-pack cases of the 12-ounce aluminum cans that are labeled 'Dr Pepper Zero Sugar.' Despite the label, the drinks inside contain the same amount of sugar found in regular Dr Pepper — about 39 grams per can — posing a health risk for people with diabetes or anyone needing to limit sugar intake. On Thursday, June 5, the FDA officially classified the recall as Class II, meaning the product 'may cause temporary or medically reversible adverse health consequences." Per the recall, th likelihood of more serious health consequences is low but still possible. The affected cans were distributed in Florida, Georgia and South Carolina, and were produced by Pepsi Beverages Company in Jacksonville, Florida, under a license from CB Manufacturing Company, Inc. Consumers can identify the recalled cases by the product code, which is listed as XXXXRS05165, and the "best by" date of Feb. 16, 2026No other Dr Pepper products or batches of Dr Pepper Zero Sugar are part of the recall. While the FDA didn't specify next steps for consumers, most stores will accept returns of recalled items. If not, the cans can be disposed of or consumed by someone who does not need to avoid sugar. Dr Pepper is one of the many brands that have had products recalled this year. Earlier this month, 1.7 million "brown cage-free and brown certified organic eggs" were recalled from the August Egg Company in nine states due to salmonella contamination. "We believe it is appropriate out of an abundance of caution to conduct this voluntary recall, as consumers may still have these eggs in their homes," the August Egg Company said in a statement shared with the FDA at the time. 'It is important to know that when our processing plant identified this concern, we immediately began diverting all eggs from the plant to an egg-breaking facility, which pasteurizes the eggs and kills any pathogens." "We are committed to addressing this matter fully and to implementing all necessary corrective actions to ensure this does not happen again," the statement concluded. If customers discover they have bought contaminated eggs, the brand encourages them to return them to the place of purchase for a full refund or throw them away. Read the original article on People
