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Half-off Ozempic? US patients paying in cash can now buy the popular weight-loss drug for less

Half-off Ozempic? US patients paying in cash can now buy the popular weight-loss drug for less

Independent10 hours ago
American diabetes patients will now be able to buy the wildly popular weight-loss drug Ozempic for half its usual price — as long as they pay out of pocket.
Danish pharmaceutical company Novo Nordisk said on Monday that it would make the drug available through its direct pharmacy service for $499 per month, compared to a list price of just under $1,000 per month.
The drug is available as an obesity medication under the alternate brand name Wegovy but will now be sold to patients with diabetes prescriptions as well.
Scientifically known as semaglutide, Ozempic and other GLP-1 agonists have rapidly transformed weight loss and diabetes treatment across the world, while at one point boosting Novo Nordisk's profits enough to raise the entire GDP of Denmark.
It comes after President Donald Trump specifically called out GLP-1 agonists for being more expensive in the U.S. than in other countries, claiming he would "slash the cost of prescription drugs" by as much as 80 percent.
He also accused European nations of "unfairly shifting the cost burden onto American patients" by using the bargaining power of their large single-payer healthcare services to force U.S. pharma companies to accept lower prices.
Big Pharma has been responsive, with Pfizer CEO Albert Bourla recently admitting that he and other firms are discussing ways to make their drugs available more cheaply.
Sales of Ozempic surged by 500 to 600 percent in the U.K. after its competitor Mounjaro announced that prices would more than triple starting on September 1.
But Trump's tariffs could also raise the price of U.S. drugs that are manufactured abroad unless pharma companies or foreign governments can agree some exemption.
Novo Nordisk launched its NovaCare pharmacy in March, offering Wegovy for $499 to patients willing to skip insurance and forego any reimbursement.
More recently the president upgraded his promise on drug prices to say he would cut them by up to "1,500 percent", which is mathematically impossible without going into negative numbers.
In Ozempic's case, reducing the list price by 1,500 percent would result in Novo Nordisk paying American patients around $14,000 for a month's supply of the drug — which is unlikely.
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Lilo & Stitch actor David Hekili Kenui Bell was battling four devastating health conditions before death at 46
Lilo & Stitch actor David Hekili Kenui Bell was battling four devastating health conditions before death at 46

Daily Mail​

time10 minutes ago

  • Daily Mail​

Lilo & Stitch actor David Hekili Kenui Bell was battling four devastating health conditions before death at 46

New details about the Lilo & Stitch actor David Hekili Kenui Bell's health prior to his death at 46 have been revealed following the release of his autopsy report. In the report, which was issued by the Hawaiʻi Police Department and obtained by People, Bell had been afflicted with four 'pathological diagnoses' at the time of his death on June 12 on Hawaii's Big Island. The autopsy was reportedly performed a week after his death, on June 19, though the results weren't completed until July 10. Bell's tragic death occurred just weeks after he made his big screen debut in Disney's live-action Lilo & Stitch film, which was released on May 23. According to the report, Bell was determined to have been suffering from acute respiratory failure, sepsis, hypertensive/atherosclerotic heart disease and morbid obesity. According to the Cleveland Clinic, acute respiratory failure occurs when the body's supply of oxygen suddenly dwindles to dangerous levels, or when too much carbon dioxide builds up in the blood. Sepsis is a potentially deadly condition in which the body's immune system defenses are overwhelmed by an infection and begin to attack tissues and organs rather than the infection. Atherosclerosis describes the hardening of the walls of arteries delivering oxygen-rich blood, which is caused by a build-up of plaque comprised of fat and cholesterol. The condition is highly associated with high blood pressure (hypertension). When arteries become too block with plaque, it can block blood flow, potentially triggering a heart attack or other serious medical condition. The increase in pressure in blocked arteries can also cause blood clots or ruptures, which could include a stroke. The report's toxicology screen reportedly showed no indication that Bell had drugs or alcohol in his system at the time of his death. Bell's autopsy report indicates that efforts were made to resuscitate him by medical professionals. The medical examiner reportedly noted that Bell still had defibrillator pads on his chest, while an airway was still present in his mouth. He also still had a blood pressure cuff on his right arm, while an IV line was place in his left arm. The actor had 'complained of difficulty breathing' shortly before dying. The medical examiner also noted the presence of an intraosseous needle in Bell's left leg, which is used to to deliver fluids or medications rapidly when medical professionals either aren't able to access veins or when there is a delay in tapping them, according to the NIH's National Library of Medicine. The report stated that Bell suffered from stasis dermatitis, a form of eczema caused by poor blood circulation in the legs, and edema, which is swelling caused by a build-up of fluid in tissues, usually occurring in the legs, feet and ankles. Despite the details, the autopsy report does not list Bell's cause of death or manner of death. An officer with the Hawaiʻi Police Department reportedly told People that the department's investigation into Bell's death was now complete. A police spokesperson previously told the outlet that the coroner's inquest investigation was standard procedure, and that no foul play was suspected in Bell's death. The actor's obituary in the Hawaii Tribune-Herald, from August 1, stated that a service was held for him at the Annunciation Catholic Church in Waimea on August 9. In a statement obtained by Bell's rep confirmed his death as she described him as a an extraordinary talent and a deeply cherished member of our BLISS ʻOhana (family).' 'David brought light, kindness, and a beautiful spirit to all who had the privilege of knowing him. He will be profoundly missed by everyone whose lives he touched,' she wrote. 'We extend our deepest sympathies to his ʻohana during this incredibly difficult time and are honoring their privacy as they grieve.' She concluded her statement by writing: 'Rest in love, dear David. Your legacy and aloha spirit will live on in the hearts of all of us. A hui hou — until we meet again.' Bell's sister Jalene Kanani Bell revealed the loss with a 'heavy heart' in a statement posted to her Facebook account in June. 'It is with a heavy heart I share that my sweet, generous, talented, funny, brilliant and handsome little brother David H. K. Bell will spend today in the company of our Heavenly Father,' Jalene's post began. 'I've been waiting for the words and mindset to properly express the joy of a human, and Prince of a Man he was, but fate pushed my hand this morning by a pre-scheduled Father's Day newsletter honoring the men in our lives. 'I met my little brother at the age of 18, on my high school graduation day, it was the most amazing surprise which I had been asking for for years, that our mom's made happen for us, and that gift has lasted a lifetime. 'While I didn't grow up with a Father, David gave me all the unconditional love I could possibly ask for and I believe that all his family and friends received the same from him. 'He was always so proud of me, his nieces and his grandnephew, constantly engaged and always coming up with fun activities to get-together. We looked forward to going to Tatihi and the Lindsey reunion together to create more family connections. 'David loved being an actor, doing voiceovers, spending time with Brutus traveling as an ambassador for Kona Brew. The film industry and entertainment was so exciting to him and I loved that he enjoyed the arts. He went to Punahou and Kalani while our dad spoke Hawaiian so his ability to deliver lines with English understanding, Indigenous knowledge and Pidgen to da Max…made him a diamond in the rough. 'You can hear him over the PA system on arrival at Kona Airport where he loved working to create an awesome and safe customer experience. His sister paid a heartbreaking tribute to the actor shortly after his death 'He was and will remain a bright and shining star. He recently made it on to the big screen with an iconic Lilo & Stich momment [sic]. He planned ahead and purchased the best seats in the house for us all to go together to opening night in Kapolei just two short weeks ago. That's one trait we didn't share, planning ahead:) We talked about and were so energized by the fans dressed in L&S gear head to toe, t-shirts, onezees, hats, mask, and the merch galore flying off the shelf as we stood in line for pop-corn. 'I said we should get shave ice after the movie and reenact the sceen but then realized the store was already closed [sic]. To celebrate him and try to ease our grief we went to get shave ice and my grandson's emotion was on point. 'To Aunty Gerry and the Kenui 'Ohana you raised an amazing human who became the most loving and supportive man in my life and I am eternally grateful. 'I share this grief with our older sister Kehau Bell, and my younger sister, Lara Leimana, who while not a Bell, loved and adored him as her own. 'He enjoyed social media and I'll be resharing some of my favorite post he made, and some I am just seeing for the first time that I missed, because they are so funny and heartwarming. 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Last month he shared video of his audition, which saw him humorously failing to eat a fake snow cone. 'My audition had some special effects,' he captioned the post. 'I'm pretty sure that's what did it... Also some random stuff... #LiloAndStitch #Stitch #Disney.'

Type 2 diabetes patients set for major shake-up in care
Type 2 diabetes patients set for major shake-up in care

Glasgow Times

time21 minutes ago

  • Glasgow Times

Type 2 diabetes patients set for major shake-up in care

The health service should move from a one-size-fits-all approach of starting everyone on the same medication, to more personalised care that aims to prevent complications like heart failure and heart attacks, according to new draft guidance from the National Institute for Health and Care Excellence (Nice). This includes making newer type 2 diabetes drugs, known as SGLT-2 inhibitors, a first-line treatment option in a move that could eventually help save tens of thousands of lives. SGLT-2 inhibitors, which include canagliflozin, dapagliflozin, empagliflozin, and ertugliflozin, are once-a-day tablets that reduce blood sugar levels by helping the kidneys remove glucose, which is passed from the body through urine. However, analysis by Nice found these drugs are under-prescribed. The new guidelines recommend patients who cannot tolerate metformin – the first-choice in type 2 diabetes medication – should start with an SGLT-2 inhibitor on its own. The decision comes after evidence suggested these drugs protect the heart and kidneys as well as controlling blood sugar, Nice said. It is estimated the change could save almost 22,000 lives once uptake reaches 90% of the population. Nice also suggests some groups of patients would also benefit from GLP-1 receptor agonists such as liraglutide or semaglutide sooner, rather than keeping them for the later stages of treatment. Semaglutide, sold under the brand name Ozempic, is licensed in the UK to treat type 2 diabetes, while its other brand – Wegovy – is also used by the NHS to help obese people lose weight. Professor Jonathan Benger, deputy chief executive and chief medical officer at Nice, said: 'This guidance means more people will be offered medicines where it is right to do so to reduce their future risk of ill health. 'This represents a significant evolution in how we approach type 2 diabetes treatment. 'We're moving beyond simply managing blood sugar to taking a holistic view of a person's health, particularly their cardiovascular and kidney health. 'The evidence shows that certain medicines can provide important cardiovascular benefits, and by recommending them as part of initial treatment, we could help prevent heart attacks, strokes and other serious complications before they occur. 'This is particularly important given that cardiovascular disease is the leading cause of death in people with type 2 diabetes.' Around 4.6 million people in the UK are living with diabetes, with nine in 10 of those having type 2. However, it is estimated that a further 1.3 million people may have undiagnosed type 2 diabetes. Nice analysed the records of 590,000 people and found SGLT-2 inhibitors are under-prescribed, particularly to women, older people, and black patients. Prof Benger added: 'The evidence from our analysis is clear. There are prescribing gaps that need to be addressed. 'The guideline update published today will help to increase equitable uptake of SGLT-2 inhibitors, which we know can prevent serious health complications.' Dr Waqaar Shah, chairman of the guideline committee, added: 'We know that SGLT-2 inhibitors are currently under-prescribed, and our health economics analysis shows that people living in the most deprived areas would particularly benefit from universal access to these treatments. 'These recommendations could help reduce health inequalities while providing better outcomes for everyone.' Elsewhere, the draft guidance suggests different treatments for diabetes patients with certain characteristics or health conditions. These include adults with cardiovascular disease, who should be offered a triple therapy including a GLP-1 receptor agonist. Meanwhile, adults diagnosed with type 2 diabetes before 40 should be offered dual therapy before a GLP-1 receptor agonist is considered, while patients with chronic kidney disease should have tailored recommendations based on their kidney function. A public consultation on the new Nice guidelines is open until October 2. Douglas Twenefour, head of clinical at Diabetes UK, said: 'This long-awaited announcement propels type 2 diabetes treatment into the 21st century. 'Boosting access to newer treatments will be transformative for people with type 2 diabetes, while ensuring the UK keeps pace with the global momentum in treating the condition. 'The majority of people with type 2 diabetes are not currently taking the most effective medication for them, putting them at risk of devastating diabetes-related complications. 'Diabetes is a leading cause of cardiovascular disease, and tailoring treatment based on individual risk could protect thousands against heart attacks and kidney disease. 'These guidelines could go a long way to easing the burden of living with this relentless condition, as well as helping to address inequities in type 2 diabetes treatments and outcomes.'

Type 2 diabetes patients set for major shake-up in care
Type 2 diabetes patients set for major shake-up in care

North Wales Chronicle

time25 minutes ago

  • North Wales Chronicle

Type 2 diabetes patients set for major shake-up in care

The health service should move from a one-size-fits-all approach of starting everyone on the same medication, to more personalised care that aims to prevent complications like heart failure and heart attacks, according to new draft guidance from the National Institute for Health and Care Excellence (Nice). This includes making newer type 2 diabetes drugs, known as SGLT-2 inhibitors, a first-line treatment option in a move that could eventually help save tens of thousands of lives. SGLT-2 inhibitors, which include canagliflozin, dapagliflozin, empagliflozin, and ertugliflozin, are once-a-day tablets that reduce blood sugar levels by helping the kidneys remove glucose, which is passed from the body through urine. However, analysis by Nice found these drugs are under-prescribed. The new guidelines recommend patients who cannot tolerate metformin – the first-choice in type 2 diabetes medication – should start with an SGLT-2 inhibitor on its own. The decision comes after evidence suggested these drugs protect the heart and kidneys as well as controlling blood sugar, Nice said. It is estimated the change could save almost 22,000 lives once uptake reaches 90% of the population. Nice also suggests some groups of patients would also benefit from GLP-1 receptor agonists such as liraglutide or semaglutide sooner, rather than keeping them for the later stages of treatment. Semaglutide, sold under the brand name Ozempic, is licensed in the UK to treat type 2 diabetes, while its other brand – Wegovy – is also used by the NHS to help obese people lose weight. Professor Jonathan Benger, deputy chief executive and chief medical officer at Nice, said: 'This guidance means more people will be offered medicines where it is right to do so to reduce their future risk of ill health. 'This represents a significant evolution in how we approach type 2 diabetes treatment. 'We're moving beyond simply managing blood sugar to taking a holistic view of a person's health, particularly their cardiovascular and kidney health. 'The evidence shows that certain medicines can provide important cardiovascular benefits, and by recommending them as part of initial treatment, we could help prevent heart attacks, strokes and other serious complications before they occur. 'This is particularly important given that cardiovascular disease is the leading cause of death in people with type 2 diabetes.' Around 4.6 million people in the UK are living with diabetes, with nine in 10 of those having type 2. However, it is estimated that a further 1.3 million people may have undiagnosed type 2 diabetes. Nice analysed the records of 590,000 people and found SGLT-2 inhibitors are under-prescribed, particularly to women, older people, and black patients. Prof Benger added: 'The evidence from our analysis is clear. There are prescribing gaps that need to be addressed. 'The guideline update published today will help to increase equitable uptake of SGLT-2 inhibitors, which we know can prevent serious health complications.' Dr Waqaar Shah, chairman of the guideline committee, added: 'We know that SGLT-2 inhibitors are currently under-prescribed, and our health economics analysis shows that people living in the most deprived areas would particularly benefit from universal access to these treatments. 'These recommendations could help reduce health inequalities while providing better outcomes for everyone.' Elsewhere, the draft guidance suggests different treatments for diabetes patients with certain characteristics or health conditions. These include adults with cardiovascular disease, who should be offered a triple therapy including a GLP-1 receptor agonist. Meanwhile, adults diagnosed with type 2 diabetes before 40 should be offered dual therapy before a GLP-1 receptor agonist is considered, while patients with chronic kidney disease should have tailored recommendations based on their kidney function. A public consultation on the new Nice guidelines is open until October 2. Douglas Twenefour, head of clinical at Diabetes UK, said: 'This long-awaited announcement propels type 2 diabetes treatment into the 21st century. 'Boosting access to newer treatments will be transformative for people with type 2 diabetes, while ensuring the UK keeps pace with the global momentum in treating the condition. 'The majority of people with type 2 diabetes are not currently taking the most effective medication for them, putting them at risk of devastating diabetes-related complications. 'Diabetes is a leading cause of cardiovascular disease, and tailoring treatment based on individual risk could protect thousands against heart attacks and kidney disease. 'These guidelines could go a long way to easing the burden of living with this relentless condition, as well as helping to address inequities in type 2 diabetes treatments and outcomes.'

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