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UM researchers identify organism behind toxins produced in harmful algal blooms

UM researchers identify organism behind toxins produced in harmful algal blooms

Yahoo23-05-2025
The Brief
Researchers have identified the organism that produces toxins found in the algal blooms that color Lake Erie every year.
The University of Michigan used samples of Lake Erie water with an overproduction of algae to isolate the species that creates the toxins.
Harmful Algal Blooms happen every year and in some extreme circumstances threaten drinking water.
(FOX 2) - Researchers at the University of Michigan are learning more about blue-green algae and the organism that produces toxins that make major algal events dangerous.
Learning more about the bacteria can help communities better manage harmful algal blooms.
Big picture view
A new study by researchers at the University of Michigan says a bacteria called Dolichospermum is responsible for the toxins found during major algal bloom events in the Great Lakes.
Samples from Lake Erie were used to identify several strains of the bacteria, which is more commonly found in warm water.
"That is interesting because we do know that the lakes are changing with climate change," said Den Uyl, who works with Cooperative Institute for Great Lakes Research.
Another finding was that the gene associated with producing the toxin was less likely to be found in areas with higher concentrations of ammonium.
Dig deeper
Michigan is at a crossroads over what to do about the algal events that return to Lake Erie every year.
Despite years of work, the state will not meet its goal of reducing chemicals that enter the lake each year. Harmful algal bloom events happen after nutrients like phosphorous and nitrogen are washed into the water and spur the overproduction of algae.
In 2014, the overproduction of algae was so extreme it threatened the drinking water of more than 500,000 people in Toledo.
Michigan and Ohio announced goals to reduce the nutrients entering the water in 2015, aiming for a reduction of 40%. But Michigan only met that goal once in the years that followed - and that was because of a drop in rainfall, which is how chemicals from farms make their way into the lake.
The Source
Michigan's Domestic Action Plan for algae events and a University of Michigan study were used to report this story.
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At-home skin cancer test could be one step closer
At-home skin cancer test could be one step closer

Yahoo

time21 hours ago

  • Yahoo

At-home skin cancer test could be one step closer

The Brief An experimental patch could bring the medical world one step closer to rapid at-home melanoma testing, eliminating the need for a biopsy or blood draw. The ExoPatch successfully distinguished melanoma from healthy skin in mice, using a test that's similar to taking a COVID-19 test at home. Researchers believe the ExoPatch could be modified, potentially helping to detect other forms of cancer, including lung, breast, colon, prostate and brain cancer. Testing for the most aggressive form of skin cancer could one day be akin to taking a COVID-19 test at home, according to researchers at the University of Michigan. The researchers have developed a silicone patch – the ExoPatch – to distinguish melanoma from healthy skin. The patch worked when tested on mice. What this means Big picture view The ExoPatch could bring the medical world one step closer to rapid at-home melanoma testing, eliminating the need for a biopsy or blood draw, researchers said. What they're saying "The star-shaped needles make puncture easier and less painful, but they are so small that they only go through the top-most layer of the skin, the epidermis, and do not draw blood," said Sunitha Nagrath, a professor of Chemical Engineering at the university and co-corresponding author of the study published in Biosensors and Bioelectronics. "A fair-skinned person with moles must go to the doctor about every six months to send off a biopsy to see if they're malignant or benign. With this test, they could instead test at home, get the results right away and follow up with a dermatologist for a positive result," Nagrath said. How it works By the numbers The ExoPatch microneedles are 0.6 mm long with a width of less than 100 nanometers (0.0001 mm) at the tip. They're coated with a gel that picks up exosomes — or "tiny packages released by cells" — from the interstitial fluid that fills the spaces between cells in the epidermis. READ MORE: Rare flu complication causing brain swelling on the rise in kids, study finds Dig deeper Exosomes contain DNA and RNA fragments that cells use to communicate with each other. Exosomes help tumors spread, and detecting them can catch cancer sooner than other methods of detection, researchers found. The researchers first tested the ExoPatch on a tissue sample of pig skin, which closely resembles human skin in thickness and composition. The team also tested tissue samples of mouse skin, half from healthy mice and half from mice injected with a fragment of a human melanoma tumor. Once researchers confirmed that the exosomes stuck to the ExoPatch, they dissolved the gel and ran the sample through the test strips. READ MORE: What is Legionnaires' disease? Symptoms, how you get it "The test successfully distinguished between melanoma and healthy tissues with a 3.5-fold darker line in melanoma samples," researchers said. What's next Researchers are planning a pilot study in humans, followed by a series of clinical trials. They believe the ExoPatch could be modified, potentially helping to detect other forms of cancer, including lung, breast, colon, prostate and brain cancer. "The potential applications are huge," Nagrath said. The Source This report includes information from the University of Michigan. Solve the daily Crossword

1-in-20 Hospital Patients Spend 24 Hours Waiting in Emergency Departments
1-in-20 Hospital Patients Spend 24 Hours Waiting in Emergency Departments

Newsweek

time5 days ago

  • Newsweek

1-in-20 Hospital Patients Spend 24 Hours Waiting in Emergency Departments

Based on facts, either observed and verified firsthand by the reporter, or reported and verified from knowledgeable sources. Newsweek AI is in beta. Translations may contain inaccuracies—please refer to the original content. Wait times for emergency hospitalizations continue to rise, with 1 in 20 Americans having to spend more than 24 hours in the emergency department before receiving a bed. This is the warning of a new study led by the University of Michigan (U-M) Medical School, which looked into the problem known as "boarding." "When patients come into an emergency department (ED) and undergo treatment, many will require ongoing care in the hospital for days. Those patients are 'admitted' and treatment teams in the ED request a hospital bed," study author and U-M Health emergency physician Alex Janke told Newsweek. "When they wait for long periods of time, usually from a treatment space in the ED, this is what we mean by boarding." Janke said the types of health conditions people might be waiting for emergency hospitalization with include sepsis, pneumonia, kidney infection, heart attack, stroke and injuries like a fall with a broken hip. Woman with drop sitting in hospital waiting room. Woman with drop sitting in hospital waiting room. EyeEmBoarding numbers were already rising before the COVID-19 pandemic began, the researchers note, but this trend accelerated in mid-2020 and stayed high for four years. While it may be exacerbated at certain points, the problem doesn't only occur in the winter months—when viral infections rise and inevitably lead to more emergency hospitalizations—the team found. In the last three years, more than 25 percent of all patients who came to a hospital's ED during a non-peak month and got admitted to the same hospital waited four hours or more for a bed. During the winter months this was closer to 35 percent. Patients shouldn't board in an ED for more than four hours for safety and care quality reasons, as per national hospital standards. The study also found that by 2024, nearly five percent of all patients admitted to a hospital from its ED during the peak months of winter waited a full day for a bed. During the off-peak months, 2.6 percent still waited that long. The research team analyzed 46 million emergency visits that led to hospitalizations at the same hospital. The data came from the electronic health record systems of 1,500 hospitals in all 50 states, from the start of 2017 to the end of September 2024. Busy hospital waiting room. Busy hospital waiting room. Kongga/Getty Images "Prolonged boarding times are an independent patient safety risk. Boarding can lead to delays in needed care, and resultant crowding in the ED can increase the risk of medical errors," Janke explained. Boarding also makes it difficult for EDs to see new patients as they arrive. "Sustained high levels of boarding, as we have seen over the past three years, suggest the health system is at risk of collapse in the event of another pandemic," Janke warned in a statement. By 2024, even in the months with the lowest rates of boarding patients, the percentage of patients who waited four or more hours for a bed was higher than it had been during the worst times of year in 2017 to 2019, according to the study. While less than five percent of patients waited more than 12 hours for a bed even at the peak times in pre-COVID years, it now rarely goes below five percent even at the lowest times of year. The worst point was January 2022, when 40 percent of patients boarded in an ED for more than four hours, and 6 percent boarded for 24 hours or longer. "The primary driver of boarding is insufficient 'downstream' hospital capacity," explained Janke. While boarding has grown nationwide and in all patient groups, the Northeast had the highest rate of boarding for 24 hours or more. Boarding during peak months also rose especially quickly for people aged 65 and over, those whose primary language is something other than English or Spanish and Black patients. "This may reflect differences in the hospitals where those patients seek care, or may reflect a bias in the care they receive in the hospital. Our study did not address this," said Janke. The researchers say their work highlights the need to prepare for winter peaks and to address the year-long issue of mismatches between acute care demands and available resources. They cite a report from an ED boarding summit held last fall by the Agency for Healthcare Research and Quality, which notes this mismatch, as well as proven solutions for ED boarding. These include smoothing out surgical schedules across the week to allow more rapid movement of ED patients to inpatient beds, streamlining discharges to earlier in the day and on weekends, using discharge lounges, using bed managers and providing alternative services for patients experiencing mental or behavioral health emergencies. The summit's participants called for more measurement and public reporting of ED boarding, more sharing of data about bed availability within regions, help for rural hospitals including telehealth consults and transferring patients needing higher-level care and efforts to reduce the need for inpatient behavioral health care. "Among the most important next steps is infrastructure to support regional capacity and load-balancing during periods of strain. Fundamentally, though, we have to build more hospital care capacity. We cannot 'optimize' our way out of this," said Janke. With the number of patients seeking emergency care rising, new short-stay units, home-based hospital-level care and specialized providers in the triage area have all been taken into account by U-M Health. A new 264-bed Michigan Medicine hospital currently under construction and due to open later this year—the D. Dan and Betty Kahn Health Care Pavilion—is intended to provide more patient space for patients admitted from the ED. Dr. Prashant Mahajan, professor and Michigan Medicine emergency medicine chair, emphasized the need for more studies on boarding and related issues nationwide, to inform policymaking. "We need rigorous research, to better understand this problem and identify sustainable solutions," he said in a statement. Janke said a House of Representatives Bill 2936 will follow next—"Addressing Boarding and Crowding in the Emergency Department Act of 2025." Do you have a tip on a health story that Newsweek should be covering? Do you have a question about boarding? Let us know via health@ References Janke, A. T., Burke, L. G., & Haimovich, A. (2025). Hospital 'Boarding' Of Patients In The Emergency Department Increasingly Common, 2017–24. Health Affairs, 44(6), 739–744. Weinick, R. M., Bruna, S., Boicourt, R. M., Michael, S. S., & Sessums, L. L. (2025, January). AHRQ Summit to address emergency department boarding: Technical report. Agency for Healthcare Research and Quality.

Tracking your sleep could lead to better grades — 5 budget-friendly trackers to shop now
Tracking your sleep could lead to better grades — 5 budget-friendly trackers to shop now

Tom's Guide

time03-08-2025

  • Tom's Guide

Tracking your sleep could lead to better grades — 5 budget-friendly trackers to shop now

Like it or not, routine is what your body needs to get a good night's sleep night after night. Yet, understandably, as your social life and academic pressures ramp up at college, bedtimes and wake-up times can go a little haywire. I've always been aware of the link between sleep and learning. So sleep was something I prioritized (as best as I could) at college. After recently graduating, I can honestly say maintaining a consistent sleep schedule was the one habit that made sure I rested well and bagged good grades, all while juggling a social life too. So, how can you make sure you're keeping it on track as best as you can? With a reliable sleep tracker. Of course, there are plenty of products you can shop in back to school sleep sales, from the best cheap dorm mattresses to cosy bedding. But if you're looking for a gadget to hold yourself accountable around going to bed and waking up at the same time each day, a sleep tracker should be on your shopping list. Yes, top of the range sleep trackers can be pricey gadgets. But I've shopped around to find you the best budget options available right now. Science shows a link between sleep regularity (i.e. going to sleep and waking up at the same time each day), improved brain function and better wellbeing among college students. Research by associate professor of neurology at the University of Michigan, Dr. Shelley Hershner, specifically found students with greater sleep consistency have better academic performance. Get instant access to breaking news, the hottest reviews, great deals and helpful tips. Meanwhile, a 2019 study published in the Sleep Research Society journal agrees that stabilizing sleep schedules can help improve well-being among students. This is because a consistent sleep schedule helps to regulate your circadian rhythm, so your body gets used to releasing sleepy hormones like melatonin at the right times of day. In turn, it's easier to fall asleep fast at night, bag quality sleep and wake up with energy for class in the morning. So, you know going to sleep on time will help your studies and overall health. But without your mom there to tell you it's time for lights out, strict bedtimes can easily become a thing of the past. This is where a sleep tracker can come in handy at college. I tracked my sleep with my Garmin watch through college and have recently experimented with a wider range of trackers including Oura, Whoop and Eight Sleep in my role as a sleep tech tester. While they all vary in the detail they go in to, even the most basic sleep tracker will deliver two key metrics — the time you fall asleep and the time you wake up. These alone can help you cement the healthy sleep habit of going to bed and waking on time. Trust me, notifications from your friendly sleep tracker telling you it's time to sleep somehow guilt trip you into halting the doom scroll and hitting the hay on time. With a student budget in mind, these are the top 5 sleep trackers I recommend shopping before the semester starts... 1. Fitbit Inspire 3: was $99.95 now $79.95 at WalmartThe Fitbit Inspire 3 is a top-rated, affordable health tracker that does a grand job of tracking basic sleep metrics like sleep timing and duration. Though you can get more in-depth sleep tracking from Fitbit if you're willing to get behind the Fitbit Premium paywall (it'll set you back $9.99/month). As a small smart watch, the Inspire 3 sits comfortably on your wrist overnight and packs 7+ days battery life. 2. Amazfit Heilo Strap: now $99.99 at AmazonFrom the Amazfit Active smart watch to the Amazfit Heilo ring, we're big fans of Amazfit health trackers here at Tom's Guide. The brand is known for producing affordable versions of industry-leading trackers and the Heilo Strap is essentially their take on the Whoop band. At $99.99 without a subscription fee, it is a great value health and recovery tracker that monitors heart rate, blood-oxygen, stress, and sleep. 3. Oura Ring 3: was from $299 now from $199 at OuraStylish and intricate when it comes to its sleep reports, the Oura Ring 3 is my favorite sleep tracker. Yet, requiring a subscription fee at $5.99 per month, it's the more premium option here - one for the students looking to seriously invest in their sleep health. That said, there's currently $100 off the Oura Ring 3 while stocks last. Plus, I've tested the Oura Ring 3 alongside the new and upgraded Oura Ring 4 and think you're getting better value for money with the previous generation — it's perfectly functional and studies show it is reliable too. 4. Milavan Smart Ring: was $59.99 now $49.99 at AmazonOf course, the Oura Ring is the gold-standard sleep tracking ring, but at $200+ and requiring a monthly subscription fee, it's not the most student budget-friendly. The Milavan is a more affordable alternative that monitors your sleep quality and recommends habits for improving your sleep health. It's rated an average of 4.4 out of 5 stars by Amazon customers who say it's "surprisingly smart". With $10 off now it's even more affordable. 5. Withings Sleep Analyzer: was $159.99 now $151.99 at AmazonIf you'd prefer to snooze wearable-free, an under mattress sleep tracker is a great option for you. The Withings sleep tracking pad slips under your mattress and keeps tabs on everything from your sleep stages to sleep duration and snoring. Our Certified Sleep Science Coach and Senior Sleep Editor Claire Davies says Withings is about as close to an at-home polysomnography test as you can get - pretty cool, huh? With 5% off at Amazon now you can get it for the slightly cheaper price of $151.99 (down from $159.99). It's another more expensive option, but a worthy investment in your sleep health and overall wellbeing.

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