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What to know about mRNA vaccines

What to know about mRNA vaccines

Toronto Star12 hours ago
WASHINGTON (AP) — So-called mRNA vaccines saved millions of lives during the COVID-19 pandemic — and now scientists are using that Nobel Prize-winning technology to try to develop vaccines and treatments against a long list of diseases including cancer and cystic fibrosis.
But this week, U.S. Health Secretary Robert F. Kennedy Jr., a longtime vaccine critic, canceled $500 million in government-funded research projects to create new mRNA vaccines against respiratory illnesses that might trigger another health emergency.
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Cuban animal lovers struggle to feed stray cats and dogs as economic crisis bites
Cuban animal lovers struggle to feed stray cats and dogs as economic crisis bites

Winnipeg Free Press

time25 minutes ago

  • Winnipeg Free Press

Cuban animal lovers struggle to feed stray cats and dogs as economic crisis bites

HAVANA (AP) — Every afternoon, 81-year-old Nélida Pérez begins her familiar walk down the cobblestone streets of Old Havana, a procession of hungry cats trailing close behind her. For years, Pérez has taken it upon herself to feed some of the street cats that roam this part of town, which is also one of the most popular tourist spots in the Cuban capital. She once relied on her own food or restaurant donations, but as the island's economic situation worsened and tourism declined, it has become increasingly difficult to provide for them. 'I have never in my life asked anyone for a plate of food to feed my cats,' Pérez told The Associated Press. 'Now I see myself in difficulties because there is no tourism and there is an economic crisis.' Since 2020, Cuba has faced a worsening economic crisis, driven by COVID-19 shutdowns, stricter U.S. sanctions, and an internal monetary reform that triggered inflation. Although the government provides vaccines, sterilization and some free clinics, it does not have the means to provide shelter and food for street cats and dogs. While official data is unavailable, activists say that many pet lovers have turned their homes — even small apartments — into shelters, but they are struggling to keep up with the demand and provide adequate care. 'The streets will kill them,' said Bárbara Iglesias, a 51-year-old pharmacist who adopted five dogs and has rescued and found homes for a dozen others. Iglesias explained that the hardest part is getting food. A 20-kilo (44-pound) bag of dog food, which lasts one dog for about 45 days, costs around $80 — a sum that is out of reach for most. This forces people to feed animals with pig organ meat (offal), chicken parts or mince meat — which are also not easy to obtain. On top of that, annual vaccines cost about $20 and a vet visit is another $10, all while the average monthly salary on the island is only about $12. Experts say that the abandonment of animals in Cuba is a result of several factors, including rising food and medicine prices, the migration of hundreds of thousands of Cubans in the last five years, and a high mortality rate among older adults. 'People are more focused on their problems, which are numerous: Cubans don't have water, they don't have electricity, and getting food is becoming increasingly difficult,' said Annelie González, one of the leaders of the Aldameros Project, a cat colony located in a park in Havana's historic center. 'Having an animal in your care involves feeding and caring,' said González, 36, who works as a restaurant manager and spends much of her income on the cats. She and a small group of volunteers began feeding 15 cats in Aldameros Park at the beginning of the pandemic. Today, they care for more than 150. Over the years, through their own efforts and some donations, they were able to install water pumps, pens for special cases, and cages for the kittens. González points to a number that she said reveals the shocking scale of the problem: at the start of the decade, roughly three abandoned cats appeared in the park each week. This year, that figure has soared to 15 per day. Back in Old Havana, Pérez recounts with sadness how she has seen people mistreat, beat and even kill stray cats. 'As long as I'm alive and healthy, and people help me,' she vowed, 'I'll always find them something to eat.' ____ Follow AP's coverage of Latin America and the Caribbean at

Americans get more than half their calories from ultraprocessed foods, CDC report says
Americans get more than half their calories from ultraprocessed foods, CDC report says

Winnipeg Free Press

timean hour ago

  • Winnipeg Free Press

Americans get more than half their calories from ultraprocessed foods, CDC report says

Most Americans get more than half their calories from ultraprocessed foods, those super-tasty, energy-dense foods typically full of sugar, salt and unhealthy fats, according to a new federal report. Nutrition research has shown for years that ultraprocessed foods make up a big chunk of the U.S. diet, especially for kids and teens. For the first time, however, the U.S. Centers for Disease Control and Prevention has confirmed those high levels of consumption, using dietary data collected from August 2021 to August 2023. The report comes amid growing scrutiny of such foods by Health Secretary Robert F. Kennedy Jr., who blames them for causing chronic disease. 'We are poisoning ourselves and it's coming principally from these ultraprocessed foods,' Kennedy told Fox News earlier this year. Overall, about 55% of total calories consumed by Americans age 1 and older came from ultraprocessed foods during that period, according to the report. For adults, ultraprocessed foods made up about 53% of total calories consumed, but for kids through age 18, it was nearly 62%. The top sources included burgers and sandwiches, sweet baked goods, savory snacks, pizza and sweetened drinks. Young children consumed fewer calories from ultraprocessed foods than older kids, the report found. Adults 60 and older consumed fewer calories from those sources than younger adults. Low-income adults consumed more ultraprocessed foods than those with higher incomes. The results were not surprising, said co-author Anne Williams, a CDC nutrition expert. What was surprising was that consumption of ultraprocessed foods appeared to dip slightly over the past decade. Among adults, total calories from those sources fell from about 56% in 2013-2014 and from nearly 66% for kids in 2017-2018. Williams said she couldn't speculate about the reason for the decline or whether consumption of less processed foods increased. But Andrea Deierlein, a nutrition expert at New York University who was not involved in the research, suggested that there may be greater awareness of the potential harms of ultraprocessed foods. 'People are trying, at least in some populations, to decrease their intakes of these foods,' she said. Concern over ultraprocessed foods' health effects has been growing for years, but finding solutions has been difficult. Many studies have linked them to obesity, diabetes and heart disease, but they haven't been able to prove that the foods directly cause those chronic health problems. One small but influential study found that even when diets were matched for calories, sugar, fat, fiber and micronutrients, people consumed more calories and gained more weight when they ate ultraprocessed foods than when they ate minimally processed foods. Research published this week in the journal Nature found that participants in a clinical trial lost twice as much weight when they ate minimally processed foods — such as pasta, chicken, fruits and vegetables — than ultraprocessed foods, even those matched for nutrition components and considered healthy, such as ready-to-heat frozen meals, protein bars and shakes. Part of the problem is simply defining ultraprocessed foods. The new CDC report used the most common definition based on the four-tier Nova system developed by Brazilian researchers that classifies foods according to the amount of processing they undergo. Such foods tend to be 'hyperpalatable, energy-dense, low in dietary fiber and contain little or no whole foods, while having high amounts of salt, sweeteners and unhealthy fats,' the CDC report said. Wednesdays What's next in arts, life and pop culture. U.S. health officials recently said there are concerns over whether current definitions 'accurately capture' the range of foods that may affect health. The U.S. Food and Drug Administration and the Agriculture Department recently issued a request for information to develop a new, uniform definition of ultraprocessed foods for products in the U.S. food supply. In the meantime, Americans should try to reduce ultraprocessed foods in their daily diets, Deierlein said. For instance, instead of instant oatmeal that may contain added sugar, sodium, artificial colors and preservatives, use plain oats sweetened with honey or maple syrup. Read food packages and nutrition information, she suggested. 'I do think that there are less-processed options available for many foods,' she said. ___ The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute's Department of Science Education and the Robert Wood Johnson Foundation. The AP is solely responsible for all content.

Harvard scientists say research could be set back years after funding freeze
Harvard scientists say research could be set back years after funding freeze

Winnipeg Free Press

timean hour ago

  • Winnipeg Free Press

Harvard scientists say research could be set back years after funding freeze

CAMBRIDGE, Mass. (AP) — Harvard University professor Alberto Ascherio's research is literally frozen. Collected from millions of U.S. soldiers over two decades using millions of dollars from taxpayers, the epidemiology and nutrition scientist has blood samples stored in liquid nitrogen freezers within the university's T.H. Chan School of Public Health. The samples are key to his award-winning research, which seeks a cure to multiple sclerosis and other neurodegenerative diseases. But for months, Ascherio has been unable to work with the samples because he lost $7 million in federal research funding, a casualty of Harvard's fight with the Trump administration. 'It's like we have been creating a state-of-the-art telescope to explore the universe, and now we don't have money to launch it,' said Ascherio. 'We built everything and now we are ready to use it to make a new discovery that could impact millions of people in the world and then, 'Poof. You're being cut off.'' Researchers laid off and science shelved The loss of an estimated $2.6 billion in federal funding at Harvard has meant that some of the world's most prominent researchers are laying off young researchers. They are shelving years or even decades of research, into everything from opioid addiction to cancer. And despite Harvard's lawsuits against the administration, and settlement talks between the warring parties, researchers are confronting the fact that some of their work may never resume. The funding cuts are part of a monthslong battle that the Trump administration has waged against some the country's top universities including Columbia, Brown and Northwestern. The administration has taken a particularly aggressive stance against Harvard, freezing funding after the country's oldest university rejected a series of government demands issued by a federal antisemitism task force. The government had demanded sweeping changes at Harvard related to campus protests, academics and admissions — meant to address government accusations that the university had become a hotbed of liberalism and tolerated anti-Jewish harassment. Research jeopardized, even if court case prevails Harvard responded by filing a federal lawsuit, accusing the Trump administration of waging a retaliation campaign against the university. In the lawsuit, it laid out reforms it had taken to address antisemitism but also vowed not to 'surrender its independence or relinquish its constitutional rights.' 'Make no mistake: Harvard rejects antisemitism and discrimination in all of its forms and is actively making structural reforms to eradicate antisemitism on campus,' the university said in its legal complaint. 'But rather than engage with Harvard regarding those ongoing efforts, the Government announced a sweeping freeze of funding for medical, scientific, technological, and other research that has nothing at all to do with antisemitism.' The Trump administration denies the cuts were made in retaliation, saying the grants were under review even before the demands were sent in April. It argues the government has wide discretion to cancel federal contracts for policy reasons. The funding cuts have left Harvard's research community in a state of shock, feeling as if they are being unfairly targeted in a fight has nothing to do with them. Some have been forced to shutter labs or scramble to find non-government funding to replace lost money. In May, Harvard announced that it would put up at least $250 million of its own money to continue research efforts, but university President Alan Garber warned of 'difficult decisions and sacrifices' ahead. Ascherio said the university was able to pull together funding to pay his researchers' salaries until next June. But he's still been left without resources needed to fund critical research tasks, like lab work. Even a year's delay can put his research back five years, he said. Knowledge lost in funding freeze 'It's really devastating,' agreed Rita Hamad, the director of the Social Policies for Health Equity Research Center at Harvard, who had three multiyear grants totaling $10 million canceled by the Trump administration. The grants funded research into the impact of school segregation on heart health, how pandemic-era policies in over 250 counties affected mental health, and the role of neighborhood factors in dementia. At the School of Public Health, where Hamad is based, 190 grants have been terminated, affecting roughly 130 scientists. 'Just thinking about all the knowledge that's not going to be gained or that is going to be actively lost,' Hamad said. She expects significant layoffs on her team if the funding freeze continues for a few more months. 'It's all just a mixture of frustration and anger and sadness all the time, every day.' John Quackenbush, a professor of computational biology and bioinformatics at the School of Public Health, has spent the past few months enduring cuts on multiple fronts. In April, a multimillion dollar grant was not renewed, jeopardizing a study into the role sex plays in disease. In May, he lost about $1.2 million in federal funding for in the coming year due to the Harvard freeze. Four departmental grants worth $24 million that funded training of doctoral students also were cancelled as part of the fight with the Trump administration, Quackenbush said. 'I'm in a position where I have to really think about, 'Can I revive this research?'' he said. 'Can I restart these programs even if Harvard and the Trump administration reached some kind of settlement? If they do reach a settlement, how quickly can the funding be turned back on? Can it be turned back on?' The researchers all agreed that the funding cuts have little or nothing to do with the university's fight against antisemitism. Some, however, argue changes at Harvard were long overdue and pressure from the Trump administration was necessary. Bertha Madras, a Harvard psychobiologist who lost funding to create a free, parent-focused training to prevent teen opioid overdose and drug use, said she's happy to see the culling of what she called 'politically motivated social science studies.' White House pressure a good thing? Madras said pressure from the White House has catalyzed much-needed reform at the university, where several programs of study have 'really gone off the wall in terms of being shaped by orthodoxy that is not representative of the country as a whole.' But Madras, who served on the President's Commission on Opioids during Trump's first term, said holding scientists' research funding hostage as a bargaining chip doesn't make sense. 'I don't know if reform would have happened without the president of the United States pointing the bony finger at Harvard,' she said. 'But sacrificing science is problematic, and it's very worrisome because it is one of the major pillars of strength of the country.' Quackenbush and other Harvard researchers argue the cuts are part of a larger attack on science by the Trump administration that puts the country's reputation as the global research leader at risk. Support for students and post-doctoral fellows has been slashed, visas for foreign scholars threatened, and new guidelines and funding cuts at the NIH will make it much more difficult to get federal funding in the future, they said. It also will be difficult to replace federal funding with money from the private sector. 'We're all sort of moving toward this future in which this 80-year partnership between the government and the universities is going to be jeopardized,' Quackenbush said. 'We're going to face real challenges in continuing to lead the world in scientific excellence.'

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