logo
My Relationship With Medication

My Relationship With Medication

WebMDa day ago
Medications are a must for most people with bipolar disorder, but my relationship with them hasn't been an easy one. While drugs designed to treat bipolar disorder can be very helpful, they also come with real risks, as do all medications. Anxiety about these risks has caused me to reject treatment at times. Here's what the journey has been like.
Refusal
I wouldn't take medication when I was first diagnosed with bipolar disorder. I didn't think I had a mental health disorder, so I simply refused to be treated for one. Unfortunately, this led to a significant decline in my functioning.
Frustration
Eventually, I very reluctantly agreed to take medication. I was put on a long-acting injectable (LAI). Serious side effects sent me to the emergency room. I had to wait for the drug to leave my system. I felt frustrated and helpless.
I later saw a new outpatient psychiatrist. He suggested the same class of medication as the LAI, an antipsychotic, but in the form of a daily pill.
I told him I didn't want to take it because I was worried about side effects. But he insisted the side effects wouldn't be as severe. Despite his reassurance, I didn't feel comfortable. I threw the pills in the garbage, but I didn't tell him that.
It wasn't too long before I had a hypomanic episode. Recognizing the symptoms, I admitted to my psychiatrist that I hadn't been taking the medication he'd prescribed. He recommended starting immediately. Otherwise, I was headed for a manic episode and most likely hospitalization. I didn't want that to happen, so I took the medication. I had side effects, but I continued, driven by the fear of another manic episode and ending up in the hospital.
Despite taking the medications exactly as prescribed, I eventually had another manic episode and was admitted to the hospital. Doctors there changed my treatment plan because of the side effects and the fact that the meds didn't seem to be working.
That's when I started lithium. I had clients on this medication when I was a therapist, so I knew that it was an old-school medication reserved for more serious cases. But I felt pretty resigned, so I agreed to take it.
Lithium requires close monitoring due to the potential for toxicity and serious side effects. As time went on, I became quite concerned about this and stopped taking it against my new psychiatrist's advice. I quickly ended up back in the hospital. Now? I take all my medications reliably.
Acceptance
My journey with medication has been deeply emotional, marked by anxiety and refusal. But over time, I've learned that medications are necessary for stability for me. I'm still concerned about the long-term effects of lithium. But I've been stable on it and an antipsychotic for some time. My blood is tested regularly to ensure lithium isn't at toxic levels or damaging my organs. I'm anxious about the results each time I get lab work done. Fortunately, I haven't had any issues. I hope to continue taking it for as long as I can.
Orange background

Try Our AI Features

Explore what Daily8 AI can do for you:

Comments

No comments yet...

Related Articles

'A little itch turned out to be skin cancer'
'A little itch turned out to be skin cancer'

Yahoo

time23 minutes ago

  • Yahoo

'A little itch turned out to be skin cancer'

Two years ago, Tom Jones noticed a mole on his chest that he "didn't bother with". The head of hospitality in Herm said "it was a little itchy" every so often but otherwise caused him no trouble. A visit to the doctor confirmed it was a melanoma that had grown rapidly under the skin. "Don't think that little itch is nothing because it's what's underneath is the problem, not what's on top," he said. "It came back to haunt me." More news stories for Guernsey Listen to the latest news for Guernsey Mr Jones said he was now a "breast less" after the 4.5 inch melanoma under his right nipple needed to be removed. He said the growth on his chest "changed colour and it began to be quite an annoyance". He got checked over at the hospital and was told it had been there "an awful long time" and it had grown significantly under his skin. An operation which saw the full removal of his right breast. Mr Jones said: "It had been growing quite rapidly underneath the skin, so therefore it wasn't treatable with a small incision, it had to be taken out completely." The melanoma was successfully cut out but Mr Johns said he still goes for regular check-ups. He urged visitors to the island to take responsibility of their safety in the sun. "I'm personally more aware of that than anyone else because I have fallen foul to not protecting myself," he said. "Don't hesitate, get that sun cream on, and if you've got an itch, get it checked. "It's everyone's personal responsibility and it's really important for you to bring some protection with you [to the island]." This story is part of BBC Guernsey's Sun Safety Campaign. Follow BBC Guernsey on X and Facebook and Instagram. Send your story ideas to More on this story Cancer diagnosis after beautician spotted change Wear SPF 50, warns islander with skin cancer How sun-conscious is our culture? Guernsey sun safety imperative, says charity Push for islanders to protect ears in the sun

Novel Access Model For Sickle Cell Disease Gene Therapy Could Be Template
Novel Access Model For Sickle Cell Disease Gene Therapy Could Be Template

Forbes

time25 minutes ago

  • Forbes

Novel Access Model For Sickle Cell Disease Gene Therapy Could Be Template

The Centers for Medicare and Medicaid Services announced in July that 33 states, the District of Columbia and Puerto Rico will join a new voluntary program intended to improve patient access to and lower costs for gene therapies targeting sickle cell disease. This was a Biden administration initiative, which the Trump administration decided to continue to implement. It ties payment for two novel gene therapies to positive clinical outcomes. This could make such treatments that cost millions be more widely accessible for patients. And if successful, it may serve as a template for future cell and gene therapy agreements. Medicaid, the joint federal and state program that provides health coverage to low-income individuals, is the main insurer for SCD patients. The Biden administration announced last year that the manufacturers of Lyfgenia and Casgevy had entered into agreements with CMS to participate in the Cell and Gene Therapy Access Model, which allows CMS to negotiate outcomes-based agreements on behalf of state Medicaid programs for cell and gene therapies, beginning with sickle cell disease treatments. Essentially this means that CMS will reimburse based on whether certain agreed-upon clinical thresholds are reached in patients. According to CMS, the participating states in the newly established access initiative represent about 84% of Medicaid beneficiaries with SCD. The program could contribute towards a sizable expansion of access to potentially transformative care in the form of two extraordinarily expensive gene therapies. The launch prices for Casgevy (exagamglogene autotemcel) and Lyfgenia (lovotibeglogene autotemcel) were $2.2 million and $3.1 million, respectively. SCD is a group of congenital red blood cell disorders, named sickle cell for their crescent shape. The condition affects millions of people worldwide. In the United States, approximately 100,000 individuals are living with the disease, which predominantly impacts people of sub-Saharan African descent. The disease alters the structure of hemoglobin, the molecule in red blood cells that delivers oxygen to organs and tissue throughout the body. As a consequence, this causes severe pain, anemia, organ damage and infections. Individuals with the disease have a shorter life expectancy, by more than 20 years on average. The most common sickle cell disorder type is sickle cell anemia. Besides pain medications to relieve symptoms as well as antibiotics to treat infections, hydroxyurea—a bone marrow suppressive agent that decreases red blood cell production—can be used to reduce the frequency of painful episodes. It has been in use since the 1980s. The Food and Drug Administration has approved several new therapeutics in the past ten years, but none are as promising as Lyfgenia and Casgevy. These two novel therapies can decrease or potentially eliminate pain crises in patients. Gene therapies such as Lyfgenia and Casgevy are administered in an inpatient hospital setting but are considered covered outpatient drugs because they're directly reimbursed and subject to standard, federally mandated Medicaid rebates. Manufacturers of the two treatments must also provide states with supplemental rebates (post-hoc discounts off of the list price) reflecting model-negotiated terms. In turn, states are obligated to implement an agreed-upon access policy for patients. According to CMS, there is also optional federal support of up to $9.55 million per state available to help with implementation of the arrangements, outreach and data tracking. In the cell and gene therapy space, science has generally outpaced commercialization. Access to very costly treatments is a challenge. Whether in the public or commercial sector, payers must find novel ways of paying for cell and gene therapies while generating evidence with respect to their real-world effectiveness and safety. Questions insurers must find answers to include: What are the health outcomes for patients in real-world settings? Do treatments fulfill the promise of a one-time cure for certain serious illnesses or disorders? Are there particular safety concerns that appear in real-world settings? Are side effects manageable? Coordinating evidence gathering as well as contracts across state Medicaid agencies is likely to yield a more efficient process while improving access for a substantial majority of SCD sufferers nationwide. It's not just SCD gene therapies that confront a formidable set of barriers to access. All cell and gene therapy manufacturers face a challenging environment. The regulatory hurdles are enormous to begin with, but manufacturing challenges following approval are considerable, too. Furthermore, patient preparation, side effect and adverse event profiles can be intolerable. This can deter patients from signing up to initiate treatment. On top of all of this, payers concerned about the high per unit costs often impose coverage restrictions, as the Tufts Center for the Evaluation of Value and Risk in Health describes. Nonetheless, gene therapies in particular hold the promise of delivering groundbreaking improvements in health outcomes across multiple disease areas. Therefore, overcoming obstacles to optimal patient access is crucial. If successful, the SCD model being experimented with could serve as a blueprint for other cell and gene therapies that have faced considerable barriers with respect to patient access.

Check Your Kitchen—Experts Say These 10 Foods Contain The Most Microplastics
Check Your Kitchen—Experts Say These 10 Foods Contain The Most Microplastics

Yahoo

time41 minutes ago

  • Yahoo

Check Your Kitchen—Experts Say These 10 Foods Contain The Most Microplastics

"Hearst Magazines and Yahoo may earn commission or revenue on some items through these links." Microplastics are found in many everyday foods like rice, tea, bottled water, and seafood. Early research suggests microplastics may contribute to health issues like oxidative stress, organ dysfunction, and metabolic or immune disruptions, though more studies are needed. Experts recommend reducing exposure by choosing loose-leaf tea, rinsing rice, avoiding plastic bottles, and opting for minimally processed or non-plastic-packaged foods. Almost everything we eat these days is transported or stored in plastic, and we've all zapped leftovers in the microwave in plastic containers. But you may not have realized that microplastics actually can be found inside the foods we eat. It's actually not a new topic. "Research into the effects of microplastic consumption has been ongoing for several decades," says Stephani Johnson, D.C.N., R.D.N., adjunct professor, Department of Clinical and Preventive Nutrition Sciences at Rutgers, The State University of New Jersey. "However, there is still much to learn regarding the average levels of human exposure, how long microplastics remain in the body, and their associated health consequences. What is currently known is that microplastics are ubiquitous in the environment, making complete avoidance virtually impossible." Studies have found microplastics throughout the human body, including in the brain, heart, colon, placenta, and more. "We are what we eat, and we are eating and being exposed to plastics in our food," Nicholas Mallos, vice president of conservation, ocean plastics, at the Ocean Conservancy, and co-author of a recent study on microplastics in commonly-consumed proteins. "While we need more research to know what exposure levels of plastics are causing human health problems, we should be concerned." What Are The Health Consequences Of Consuming Microplastics? Emerging evidence suggests that potential harm may depend on several factors, including the amount consumed, as well as the type, size, and shape of the microplastic particles. "At the cellular level, studies have shown that microplastics can contribute to oxidative stress, DNA damage, organ dysfunction, and disruptions in metabolic, reproductive, and immune functions, as well as neurodevelopmental toxicity," Johnson says. Unfortunately, there is still much we don't know about microplastics in food. "Our study demonstrates the need for further research to better understand microplastics in the most commonly consumed foods, including precisely where these microplastics are coming from and the potential human health risks," Mallos says. Ahead, the foods that research has found to contain a measurable amount of microplastics: Tea Many commercial tea bags are made with polypropylene, a type of plastic used to seal the bags and maintain their shape. "When steeped in hot water, these bags can release microplastics into the tea. To avoid potential ingestion of microplastics, using loose leaf tea with a stainless steel or other non-plastic tea infuser is a safer and more sustainable alternative," Johnson says. Rice "Studies have shown that rice can contain relatively high levels of microplastics, likely due to contamination of soil and irrigation water," Johnson says. Rinsing rice thoroughly before cooking has been found to reduce its microplastic content by approximately 20–40%. Ultra-Processed Foods There's evidence that food processing is a likely source of microplastic contamination. Research has found that highly-processed protein products, such as chicken nuggets, tofu, and plant-based burgers, contain significantly more microplastics per gram than minimally processed products, such as wild Alaska pollock and raw chicken breast, Mallos says. Bottled Water When exposed to heat—such as being left in a hot car—or subjected to physical stress, like squeezing, plastic water bottles can release microplastics into the water. "Among various types, single-use plastic bottles tend to release the highest amounts of microplastics, followed by reusable plastic bottles," Johnson says. "In contrast, stainless steel and glass bottles do not degrade or leach microplastics, making them a safer and more sustainable choice for drinking water." Salt Believe it or not, even salt—a naturally occurring mineral—isn't safe from microplastics. Research has found that salt can contain large amounts of microplastics, reflecting the broader problem of environmental pollution. Himalayan pink salt contains the greatest amounts, followed by black salt and sea salt, Johnson says. Fruits & Vegetables "Due to widespread environmental contamination, fruits and vegetables can contain measurable amounts of microplastics," Johnson says. Some types of produce are more susceptible than others, like root vegetables (such as carrots, potatoes, and beets), because they absorb microplastics from contaminated soil and rainwater through their root systems. But all types of plants can absorb microplastics through their roots. Honey Even honey may be contaminated by microplastics, which is also a concern due to widespread environmental contamination, Johnson says. Plant-Based Foods In the study co-authored by Mallos, microplastic particles were found in tofu, plant-based nuggets, plant-based fish sticks, and plant-based ground beef. Fresh Seafood Microplastics in the ocean accumulate in fish and shellfish, ultimately impacting humans, who consume seafood containing these particles, Johnson says. Bottom-feeding species, such as clams, mussels, oysters, catfish, halibut, flounder, and cod, tend to have higher concentrations of microplastics compared to other marine organisms. Processed Seafood Processed seafood fares no better. Research shows breaded shrimp, pollock fish sticks, and shrimp also contain microplastics, Mallos says. You Might Also Like Insanely Easy Weeknight Dinners To Try This Week 29 Insanely Delicious Vodka Cocktails Solve the daily Crossword

DOWNLOAD THE APP

Get Started Now: Download the App

Ready to dive into a world of global content with local flavor? Download Daily8 app today from your preferred app store and start exploring.
app-storeplay-store