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The best L-arginine supplements to support heart health

The best L-arginine supplements to support heart health

Chicago Tribune19-05-2025

Over 80 million Americans have some form of cardiovascular disease. Arginine, also known as L-arginine, is a naturally occurring supplement that can help with many aspects of heart health. L-arginine can help people with clogged arteries or congestive heart failure by relaxing blood vessels and improving circulation.
L-arginine also has been linked to lowering blood pressure, helping with kidney function, and hastening wound healing. For a high-quality, time-released L-arginine supplement, the top choice is Thorne Research Perfusa-SR.
Who shouldn't take L-arginine supplements?
L-arginine affects circulation by relaxing blood vessels. Having a deficiency in L-arginine is rare, but a supplemental dose of the amino acid can be helpful for some conditions. However, anyone taking blood pressure medication, anticoagulants, heart medication, treatment for diabetes or erectile dysfunction pills, pregnant women and asthmatics should consult their doctor first before using L-arginine supplements.
What are the side effects of L-arginine supplements?
While clinical tests show that users can take L-arginine safely for up to three months, you should be aware of some minor side effects. Diarrhea, bloating, abdominal pain and gout have been reported by some users. Asthma patients should be aware that L-arginine could make breathing more difficult. Side effects from using L-arginine long-term have not been studied.
What do L-arginine supplements taste like?
In general, L-arginine tastes quite bitter due to its alkaline nature. You may want to consider mixing the powdered form of L-arginine with other liquids to mask the taste. Some L-arginine products are flavored.
Powder vs. capsule
Whether you choose powder or capsules, you will still be getting the same amount of L-arginine. There are some benefits to powder worth noting. It is slightly more cost-effective and requires just one dose daily. You can mix the powder form with other liquids and ingredients. The powder is also more quickly absorbed by the body, so the effects are felt more quickly. Pills are still a viable option for many because of their portability, the lack of bitter taste and they're less messy.
Forms of L-arginine
There are three different forms of L-arginine.
No preservatives
Look for L-arginine supplements without artificial preservatives or added sugar. Some L-arginine supplements include additional vitamins and folate for dietary support.
Basic unflavored L-arginine pills are available from $6-$10 per monthly supply, but they are not USDA-approved. Higher quality pills and powders are found in the $10-$20 range, while the premium L-arginine supplements that include additional nutritional support and flavor options will run $20 or more.
Are there other sources of L-arginine?
A. L-arginine occurs naturally in beef, poultry, fish, grain, seeds, nuts and dairy products. Consider increasing your intake of some of these foods if it meets your dietary needs.
Can I take L-arginine if I am taking lysine?
A. Take lysine and L-arginine several hours apart, as the two substances negate each other's effect if taken together.
Top L-arginine supplement
Thorne Research Perfusa-SR
What you need to know: This L-arginine supplement has a unique time-release that provides a consistent amino acid level throughout the day.
What you'll love: The manufacturer supplies supplements to the U.S. National Teams. Significant research studies confirm the product's positive effect on heart health. It has excellent absorption due to the sustained-release formula.
What you should consider: You will pay more for this product's unique benefits compared to other products similar to it.
Top L-arginine supplement for the money
NOW Foods Double Strength L-Arginine
What you need to know: Affordable and effective, this L-arginine supplement works as a nitric oxide precursor to dilate blood vessels.
What you'll love: The product is made in a facility that is certified to be kosher and free of GMOs. The manufacturer has been family-owned for over 50 years, employing high-tech technology and active in charitable causes.
What you should consider: Some reports of minor heartburn have been reported, and a small percentage of users did not notice any difference.
Worth checking out
Jarrow Formulas Arginine
What you need to know: This trusted brand of L-arginine supplement uses the highest grade ingredients in its production.
What you'll love: Formulated for exceptional absorption, this L-arginine supplement has no fillers or dyes and has been certified 99% pure. It supports heart and kidney health.
What you should consider: Single bottles are not available for purchase on all online retailers, where only two-bottle packs are sold.
BestReviews spends thousands of hours researching, analyzing and testing products to recommend the best picks for most consumers. BestReviews and its newspaper partners may earn a commission if you purchase a product through one of our links.
Distributed by Tribune Content Agency, LLC.

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Talkiatry Chief Medical Officer and co-founder Dr. Georgia Gaveras, DO named to Modern Healthcare's 50 Most Influential Clinical Executives Class of 2025

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We expressly disclaim any obligation or undertaking to release publicly any updates or revisions to any forward-looking statements contained herein to reflect any change in our expectations or any changes in events, conditions or circumstances on which any such statement is based, except as may be required by law, and we claim the protection of the safe harbor for forward-looking statements contained in the Private Securities Litigation Reform Act of 1995. Company Contact:Jaclyn Jaffe (781) 652-4500ir@ Media Relations Contact:Tony Plohoros6 Degrees(908) 591-2839tplohoros@ in to access your portfolio

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