Revolutionize Your Health Routine With New NAD+ Patches
"Hearst Magazines and Yahoo may earn commission or revenue on some items through these links."
It's 2025, and NAD+ is to wellness as pilates is to working out. NAD+ is a naturally occurring coenzyme in your body that's in charge of energy metabolism, DNA repair, and even stem cell rejuvenation. Celebrities like Hailey Bieber, Kendall Jenner, and Gwyneth Paltrow swear by it, often hooking themselves up to NAD+ IVs. It's available in pill form and various elixirs as a supplement, but now, thanks to Barrière and their innovative vitamin patches, you'll be able to get it into your system via a cute little sticker.$17.98 at mybarriere.com
Since NAD+ has so many alleged benefits, including boosting metabolism and improving cognitive function, it sounds like something we should ideally all be able to get at any time. But to reap the benefits of NAD+, the most potent option is an IV drip, and it comes with red tape; it can cost anywhere between $300 to $2,000 for a typical 500 mg dose, and it is a slow process that takes anywhere from two to four hours. Speeding up an NAD+ IV can be painful (Joe Rogan described a quicker NAD+ infusion as 'excruciating' on his podcast), and regardless of how long it takes, any NAD+ drip can cause side effects like vomiting, nausea, dizziness, flushing, or redness. 'I am not a fan of IVs because I think they give you too much at once, and your body doesn't really know what to do with that high of a dose,' says Amanda Kahn, MD, a longevity doctor who recommends shots instead of IVs.
Shots can still be difficult to get, and they're as expensive as infusions, so many people are still on the hunt for other routes. Oral supplements have shown some promise, but there's limited data, according to a 2023 study in The Journals of Gerontology: Series A. The study found that, overall, oral supplements that use NAD+ precursors have shown to be safe, well-tolerated, and may boost overall NAD+ levels in the body. But if you don't want to take another pill, a patch may be the best option.
'Barrière's NAD+ patch uses a transdermal delivery system to gently release NAD+ through the skin over time, allowing for consistent absorption directly into the bloodstream,' says Sogol Ash, MD and medical advisor to Barrière. 'It bypasses the digestive system and liver, which makes it ideal for people who want a non-invasive, on-the-go option to boost NAD+ levels without needing an IV or capsule.'
Barrière co-founder Cleo Davis-Urman says she wanted to make the patch as a more accessible option, using NR, a precursor to NAD+ that converts to the peptide once it's in your system. 'The goal of the patch is to replenish declining NAD levels so that your body starts to produce more on its own,' she says. 'It supports cellular energy production, metabolic health, healthy aging, muscle recovery, cognitive function, and more. I call it a fountain of youth.'
The patch also closely mimics the delivery system of an IV treatment, though it delivers far less at once. You'll apply two small patches, which have a total of 18 mg of NR, every other day. 'This follows the recommended treatment using IV therapies,' Davis-Urman says. 'It gives your body a day of rest in between, which is scientifically studied to be more beneficial.'
And thanks to its unique delivery method, Davis-Urman says the patch also doesn't come with the same unpleasant side effects as IVs or oral supplements. 'IVs can shock your system, while oral supplements can cause nausea as your body acclimates to the peptide. The slow transdermal delivery is letting your body, over eight to 12 hours, get a small and consistent dose,' Davis-Urman says.
As for how much NAD+ is actually getting in your system? The jury's still out, since there's no real way to measure it; you can't tell in a blood test like you would for something like vitamin D, though Ash says that tests are currently being developed. 'In the meantime, I test downstream effects through functional labs, including improvements in mitochondrial markers, inflammation, and shifts in biological age,' she says. 'But the most meaningful feedback often comes from how someone actually feels. Many people notice real improvements in energy, sleep quality, mental clarity, and recovery within just a few weeks of consistent patch use.'
Keep in mind that if you want the most benefit out of NAD+, an IV is still the best option, according to Alexander GolBerg, MD, DO, who calls it the 'Rolls-Royce' of ways to get NAD+ into your system. 'In the patch, they don't know how much is absorbed,' he cautions. Still, doctors agree that patches like Barrière's are low risk, so we're willing to stick some on to find out the benefits for ourselves.
You Might Also Like
The 15 Best Organic And Clean Shampoos For Any And All Hair Types
100 Gifts That Are $50 Or Under (And Look Way More Expensive Than They Actually Are)
Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles
Yahoo
4 hours ago
- Yahoo
A Study Says Gray Hair May Be Reversible
"Hearst Magazines and Yahoo may earn commission or revenue on some items through these links." A study links graying hair to stem cells getting stuck, unable to color new hair growth. Stem cells travel back and forth within compartments, but when they get stuck in one compartment, they cannot regenerate into pigment cells. Restoring mobility of the cells could allow the continuation of pigment production, eliminating graying hair. If only our pesky stem cells didn't get stuck in place after a while, maybe we wouldn't have gray hair. Really. In a study published in the journal Nature, researchers from New York University's Grossman School of Medicine revealed how stuck melanocyte stem cells (McSCs) can't make the protein needed to pigment hair, potentially explaining gray hair. Using mice as the research subjects, the team found that McSCs travel between compartments of developing hair follicles in a healthy situation. The differing compartments allow the McSCs to mature and pick up the protein that can regenerate into pigment cells and continually color hair as it grows. These McSCs shift back and forth between maturity levels over time as they continually move between the compartments, a unique aspect of the McSCs. But in some cases, the McSCs can get stuck in the hair follicle bulge compartment and become unable to move back to the germ compartment, where the WNT proteins encourage the cells to regenerate into pigment cells. Getting stuck means no pigment cells, which means gray hair. 'It is the loss of chameleon-like function in melanocyte stems cells that may be responsible for graying and loss of hair color,' Mayumi Ito, study senior investigator and professor in the Ronald O. Perelman Department of Dermatology and Department of Cell Biology at NYU Langone Health, says in a news release. 'These findings suggest that melanocyte stem cell motility and reversible differentiation are key to keeping hair healthy and colored.' Basically, if the McSCs can keep moving—or, if they get stuck, we can somehow prod them to get going again—we should expect more colorful heads of hair the world over. 'Our study adds to our basic understanding of how melanocyte stem cells work to color hair,' Qi Sun, postdoctoral fellow at NYU Langone Health, says in the release. 'The newfound mechanisms raise the possibility that the same fixed positioning of melanocyte stem cells may exist in humans. If so, it presents a potential pathway for reversing or preventing the graying of human hair by helping jammed cells to move again between developing hair follicle compartments.' The McSCs focus on pigment-making, and are different from cells responsible for hair growth, Sun says, so hair can to continue growing even without pigment. The NYU study showed that as the hair regrowth process aged, the number of McSC's lodged in the follicle bulge continued to increase. At some points, this non-pigment producing follicle bulge contains roughly 50 percent of all McSCs. The McSCs that remained mobile retained their ability to produce pigment, but with the ever-shifting requirements of McSCs breaking down over time, the rise of gray hair coincided with aging. And while stress has also been associated with graying hair, unrelated Harvard research says that stress simply increases the hair regrowth pattern, speeding up the aging process for hair follicles. 'For unknown reasons, the melanocyte stem cell system fails earlier than other adult stem cell populations, which leads to hair graying in most humans and mice,' according to the NYU study. The next step for the NYU team involves looking at how we can get McSCs, once stuck, moving again. Because once they move, they create pigment. And that could mean the end of gray. You Might Also Like The Do's and Don'ts of Using Painter's Tape The Best Portable BBQ Grills for Cooking Anywhere Can a Smart Watch Prolong Your Life?
Yahoo
14 hours ago
- Yahoo
The Top Food Safety Mistake You're Making With Produce
"Hearst Magazines and Yahoo may earn commission or revenue on some items through these links." For some, the act of chopping, peeling and coring vegetables for half an hour after a long day can be meditative. For the rest of us, however, it's a total drag — and truly, nothing makes us crave takeout like the thought of prepping mirepoix vegetables on a work night. Our solution? Do it ahead of time. As any cook or recipe developer will tell you, tackling all (or most) of your produce prep in advance is one of the best ways to streamline the cooking process, so you can make a fresh, flavorful meal — or enjoy an easy, healthy snack — on the fly. There is, however, one small catch when it comes to pre-peeling or chopping your fresh fruit and vegetables: The moment you cut into them, they become much more vulnerable to nutrient loss, oxidation and harmful pathogens — and this only worsens if your produce sits out on the counter. So the next time you think about chopping up that beautiful lettuce for your salad be sure to avoid these food safety mistakes. Instead, learn how to properly store your prepped fruit and vegetables so they stay flavorful, fresh and ready to incorporate into your huge fans of leaving the skin on fresh produce like carrots, cucumbers, and potatoes. Not only is it a rich source of fiber and antioxidants, but the skin can also add extra flavor and texture to meals. Of course, that skin plays another vital role — it protects what's inside. 'Once fruits and vegetables are cut, peeled or processed, their protective outer layers are compromised,' says food safety expert Dr. Darin Detwiler. This leaves them vulnerable to pathogens like salmonella, listeria, and E. coli. Produce like apples and avocados will also quickly begin to oxidize, which — while harmless — is still less than appetizing. Before you even pick up a knife or peeler, make sure to give your produce a thorough scrub. Otherwise, you may contaminate your fruits and vegetables before they even get to the fridge. 'Bacteria on the outer surface can transfer inside during cutting,' says Dr. Detwiler. Waiting until after the produce is cut or peeled to wash it can be worse than not washing it all, as 'water can actually spread bacteria inward' once the skin is broken, he explains. To wash your produce, rinse under cold running water, using a designated brush to remove dirt or wax. Never use soap or bleach! Fruits and vegetables are porous, meaning they'll absorb anything you put on them, even after rinsing. If your produce is especially dirty, or you're worried about pesticides, you can also try a cold-water soak by adding 1 tsp of baking soda to every 2 cups of water (use enough water to fully submerge your produce), then soaking for 12 to 15 minutes. However you choose to wash your produce, make sure to dry it thoroughly before storing — and remember that all produce spoils faster after it's been washed, so it's best to wash it right before you're ready to use it.$5.60 at When you finally get to chopping, make sure your work station is thoroughly clean and sanitized. Good Housekeeping Recipe Editor Susan Choung recommends using a different cutting board for produce than the one you use for raw meat or seafood, which is important for preventing cross-contamination (especially if you're planning on serving produce raw). Alternatively, you can wash your cutting board with hot water and soap before using it to cut fruits and vegetables. Once you've done the hard work of selecting, cleaning, and prepping your fresh farmers' market finds, it's time to pop it straight in the produce Well, not exactly. While Dr. Detwiler recommends promptly refrigerating most produce after peeling or cutting — making sure the temperature stays at 40°F or below — not all fruits and vegetables get stored the same way, nor do they have the same shelf life. Cantaloupes, for example, are at higher risk for contamination than other fruits, says Dr. Detwiler. And as such, they should be eaten immediately once cut. Cut fruits and vegetables should never be left at room temperature for more than two hours — or one hour if the room is hotter than 90 degrees Fahrenheit, he says. Clearly labeling and dating containers is another way to ensure that fruits and vegetables get used up. Below, you can find Dr. Detwiler's recommendations for storing common fruits and vegetables after prepping, as well as an estimation of their typical shelf life. Apples: 3–5 days; use lemon juice to prevent browning Bananas: 1-2 days once peeled, though best eaten fresh; may be frozen Berries (e.g. strawberries, blueberries, and raspberries) 1–3 days; should be stored loosely covered and unwashed until ready to eat Citrus fruits: 3–4 days when sealed Melons (e.g. watermelon): 3–4 days; should be refrigerated immediately. Cantaloupe: should be consumed immediately Mangoes, papayas, and pineapples: 3–5 days; should be sealed in airtight containers Avocados: 1–2 days if covered tightly with the pit left in place Leafy greens (e.g. lettuce and spinach): 3–5 days when dried and stored with a paper towel Carrots: 1–2 weeks when submerged in water (which should be changed every 2–3 days) Bell peppers: 3–5 days in a resealable bag or airtight container Cucumbers: 1–3 days when wrapped in paper towels Tomatoes: 2–3 days if stored cut-side down Onions: 7–10 days when tightly wrapped Garlic (peeled): one week in a sealed container Mushrooms: 1–2 days; should be kept in a paper or ventilated container Broccoli and cauliflower: 3–5 days in sealed bags Celery: 1–2 weeks when wrapped in foil or submerged in water (with regular water changes) No matter how hard you try, you'll inevitably encounter a moldy or rotten piece of produce; it's simply a fact of life. The important thing is to quickly identify and toss the offending fruit or vegetable. 'If produce looks slimy, smells sour, or shows signs of mold, throw it out.' Finally, if you don't think you'll be able to use up fresh produce right away, try freezing it: Frozen berries, bananas, and leafy greens are great for adding to smoothies and soups and are often cheaper than the store-bought versions. Note it's better to freeze produce closer to the date you bought it from the store. If you waited a few days, instead, try cooking to extend its shelf life — throw it into a stir-fry, fold into a frittata or make a jam. You Might Also Like 67 Best Gifts for Women That'll Make Her Smile The Best Pillows for Every Type of Sleeper
Yahoo
2 days ago
- Yahoo
IBM all-time high, Universal Health falls, Topgolf Callaway rises
Market Domination co-host Yahoo Finance host Julie Hyman tracks today's top moving stocks and biggest market stories in this Market Minute. IBM (IBM) stock hit an all-time high and surpassed a $250 billion market cap. Universal Health Services (UHS) stock is under pressure after the company presented at the Goldman Sachs Global Healthcare Conference. Topgolf Callaway (MODG) stock is surging after a board member purchased $2.5 million in shares last week. Stay up to date on the latest market action, minute-by-minute, with Yahoo Finance's Market Minute. It's time for Yahoo! Finance's market minute. Shares of IBM hitting all-time highs on Monday. The stock also surpassing a market cap of $250 billion for the first time in the company's history. That move in the stock coming amid recent acquisitions, helping the company enter the high-growth software and services space. Universal Health Services under pressure following its presentation at the Goldman Sachs Global Healthcare Conference. The company's CFO, Steve Filton, saying labor shortages have impacted staffing and subacute facilities, according to Bloomberg. Filton also noted that the length of stay for patients is still higher than pre-COVID levels. Shares of Topgolf Callaway Brands surging in today's session, a securities filing showing that a board member purchased about $2.5 million worth of shares last week. The purchase signaling a boost of confidence in the tech-enabled golf company. And that's your Yahoo! Finance market minute. For more on what's trending on Yahoo! Finance, scan the QR code below. Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
