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'I know my lung cancer is terminal but I don't feel ill'

'I know my lung cancer is terminal but I don't feel ill'

BBC News3 hours ago

A woman who was diagnosed with terminal cancer has praised the blood test which allowed her to get treatment sooner. Rebeca Proctor, 41, from Carlisle, was diagnosed with stage 4 non-small-cell lung cancer in January.At the time she was part of a pilot study looking at whether a blood test could be used to determine the genetic variant of a cancer quicker than a typical biopsy.She said the blood test, also known as a liquid biopsy, had "saved her life".
A liquid biopsy can detect tiny fragments of tumour DNA which circulate in the blood. This can help doctors figure out a cancer's specific genetic variant.By knowing this, a more personalised treatment can be offered, Prof Alastair Greystoke at Newcastle Hospitals said.After suffering from breathlessness for months and going back and forth to the GP, Ms Proctor had an X-ray and CT scan which revealed she had cancer."It was in my lungs, it was my spine, my hips, my lymph nodes," she said. "It was scary."
She was at hospital taking part in a pilot for patients with suspected lung cancer which was looking at the effectiveness of a liquid biopsy in these cases. The blood test confirmed the genetic variant of Ms Proctor's cancer 10 days before a typical tissue biopsy. It meant she could be started on the treatment best tailored to her cancer far sooner."My oncologist said if I wasn't started on the treatment I would have had weeks to a month left [to live]," she said. "I wasn't ready for that."
'Got my life back'
Since starting Brigatinib in January, a drug tailored to the genetic variant of her advanced non-small cell lung cancer, Ms Proctor said she has been able to live a normal life again even though she still had a terminal diagnosis. She said she started feeling better about a week or so after taking the medication which she continues to take. "It's given me my life back which I hadn't had for months," she said.She has four children, including a three and six-year-old."My health's back and I can do all the things I can do with the kids now," she said."It sounds silly but I know I'm terminal but I don't feel ill."NHS England announced last month that following the liquid biopsy pilot, the blood tests had been rolled out across the country for suspected lung cancer and advanced breast cancer patients.It said it would help reduce the time taken for people to access targeted therapies and reduce unnecessary treatment such as standard chemotherapy.
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  • Daily Mail​

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He said that Dr Hakmi had scored only 84 on an IQ test, putting him below 86% of the general population, adding: "That's very bad - it suggests it would be hard to function as a surgeon or as an educator at that level." He had also been assessed by two neuropsychologists, who had performed memory tests, with "very surprising" and sometimes "astonishing" results which he said raised a "serious concern about whether he was putting forward his best effort" in the tests. Dr Hakmi was unable to recall more than four single digit numbers in a row during one examination and scored so low in the tests that in some respects he was below 99% of the population, despite continuing to work as an "educator" at undergraduate level. "You scored astonishingly badly for someone operating at the level you are describing this morning," he said, referencing the fact Dr Hakmi had spoken with pride in the witness box of his work with Cambridge University. "I understand you feel very strongly that you have suffered greatly as a result of this second stroke," he continued. "I understand that you feel the reason you have suffered as badly as you have is because of mistakes or negligence. I understand it must make you angry." He went on to suggest that Dr Hakmi's "sense of injustice" may have led to a desire to make sure that "people fully understand the impact this has had on you." "Is it possible when you went to be tested that you performed worse than you should have done because you were trying to demonstrate to them just how big the impact had been? "One possibility which I put to you is that you were deliberately underperforming." But Dr Hakmi denied playing up for the medics who assessed him pre-trial, telling the court he had found the tests "exhausting." He denied being dishonest with the doctors, telling the judge, "it was an exhausting environment when the tests were done in a lengthy and not organised manner. "Anybody can fail a test but they must be given the best chance," he continued. "I definitely have a memory problem, slow effort. I have done everything to mitigate my losses. I know definitely I'm not as before I had the stroke." Mr de Bono pressed on, referring to a "memory and malingering" test which had resulted in a score "very nearly at chance level," telling Mr Hakmi: "Someone giving random answers would nearly have scored as badly as you." Accusing him of "not being straightforward" with those who assessed him pre-trial, he said: "There is a pattern emerging. In any given situation, you will try and say whatever you think is going to help you most to achieve whatever your aim is." But Dr Hakmi hit back: "I have been straightforward in everything in my life. I have aimed to be a surgeon again, but I have failed." The damages claim is against the East and North Hertfordshire NHS Trust, which runs the Lister Hospital, and the Norfolk and Norwich University Hospital NHS Foundation Trust, where the remote stroke doctor who spoke to Dr Hakmi was based. The trusts both deny blame, saying he was "at all times treated with reasonable care and skill by highly competent clinicians." He was assessed as being unsuitable for thrombolysis treatment because his symptoms were not serious enough and it was too late after the onset of his symptoms. Such treatment can also be risky, carrying a significant risk of brain haemorrhage and death, said the NHS barrister, and even if he had been given it the outcome would probably have been the same. The trial continues.

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