
'Measles capital of North America': Alberta doctors sound alarm on immunization
Measurable difference
Article content
In a statement emailed to Postmedia after press time Tuesday, the Ministry of Primary and Preventive Health Services said recent data shows current outreach and immunization efforts are making a measurable difference.
Article content
'Between March 16 and July 12, more than 82,000 measles vaccines were administered across Alberta — an increase of more than 55 per cent compared to the same time last year,' the statement said.
Article content
'In the South Zone, where targeted efforts have been underway, vaccine uptake rose by 121 per cent. In the North Zone, it rose by 94 per cent. A call-out campaign for parents of 6–11-month-olds in affected zones led to a 259 per cent increase in doses — about 6,000 more than the same period last year.'
Article content
The gains reflect the impact of expanded clinic access, early-dose eligibility in high-risk zones, and the extended Don't Get Measles, Get Immunized campaign, the release said.
Article content
Article content
The ministry said the routine immunization schedule was updated for measles-containing vaccine in January 2021.
Article content
As of Jan. 1, 2021, the second dose shifted to 18 months of age from between four to six years of age to support children being fully immunized by the time they start participating in preschool, pre-kindergarten, and kindergarten programs that are often co-located in schools, the release said.
Article content
'Alberta's government isn't considering linking school registration with immunization records.'
Article content
The Canadian government urges measles vaccination for all eligible individuals, including two doses at 12 and 18 months of age.
Article content
Smith said the provincial government is now allowing everyone to get their two doses by the age of two.
Article content
'Before we waited until kindergarten, but now so many kids are going into daycare, so we've moved that back, but we also make a microdose available to those parents who want that extra protection and so they can get a smaller dose,' she said.
Article content
Article content
For now, Alberta is reaping the benefits of days when vaccine rates were higher.
Article content
Smith said she's 'pleased to see that we still have about a 90 per cent overall vaccination rate by the time young people get to be 17 years old — 95 per cent is what they recommend. But we're glad to see that the message is getting out,' she said.
Article content
Child, adult, pregnant woman alike, if you're in the room with an infected person and you're non-immune, your chances of getting the airborne illness is very, very high, said Ladha.
Article content
'That represents a perfect storm where our children, grandchildren, nephews and nieces and family members will be at risk, increased risk in getting measles because they've gone to school in September or because they've brought it home from school to infect the children who are still at home,' Talbot said.
Article content
There have been recent ICU admissions with measles victims requiring care, said Dr. Lynora Saxinger, an infectious diseases specialist with the University of Alberta.
Article content
'I have just recently been called about pregnant women who have measles in pregnancy. I've also been called about transplant patients with measles.
Article content
'The likelihood that there will be severe outcomes with really significant critical illness or death is just going up, because the longer we have circulation of disease and more cases that happen, that's basically just a matter of numbers and risk, and it's just a matter of time, unfortunately,' Saxinger said.
Article content
Within the past few months, the province's health zones have stopped posting the areas of exposure to measles, where individuals travelled from their doctor's office to a lab to a radiology site to a store.
Article content
'We don't see that from those sites anymore, because the volume is simply too high for them to be able to catch up. And so we just know that there's more transmission and more cases than are even being detected, and we're probably seeing, to some extent, the tip of the iceberg on the hospital side,' she said.
Article content
Article content
Practical considerations
Article content
As a doctor, Talbot said, he's an optimist in that he believes public health threats can be addressed — noting that more than 90 per cent of Albertans got at least one COVID vaccination during the pandemic.
Article content
All American states have laws requiring certain vaccines for students to attend school, although a number of states allow for exemption on the basis of religion or philosophy, according to the National Conference of State Legislatures.
Article content
In Canada, Ontario and New Brunswick have made immunizations mandatory for school attendance.
Article content
It may be time for a public debate on requiring measles immunizations for school attendance in Alberta, Talbot said.
Article content
'The second (way to address school spread of measles) is to make sure that people are aware that if measles does strike a school and starts to spread, that it may be necessary to send unimmunized students and unimmunized staff home so that they are protected for the time until all of those people who have been exposed are safe to return,' he said.
Article content
Article content
Saxinger said for those who aren't immune, the current guidance for quarantine after measles exposure is 21 days.
Article content
'That's to try to contain the infection and reduce the successive rings of spread — and that's very disruptive, if you think about that occurring in a school or in a workplace. It is a really strong practical argument to make sure that your immunization is up to date, and the immunization of your children is up to date,' Saxinger said.
Article content
What to do if your child is not immunized
Article content
The experts agreed there's a unique window in the next month.
Article content
'It takes time to book an appointment, and then the child's body needs 10 to 15 days to get the maximum protection. So book your appointment now for anyone going back to school and anyone under the age of five who's not immune in your household. That's the most important back-to-school preparation you can do even more than buying a backpack or a lunch box,' Talbot said.
Hashtags

Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles


Vancouver Sun
7 hours ago
- Vancouver Sun
U.S. Batten disease experts who lobbied B.C. to reinstate drug in Charleigh Pollock case had relationships with drug company
Almost all the U.S. research experts the B.C. government leaned on to make a decision to reinstate a $800,000-a-year drug treatment for a 10-year-girl have, or had, relationships with the pharmaceutical company that manufacturers the drug or foundations that advocate for treatment, a Postmedia examination has found. The province's decision went against its own 58-member advisory committee. Of the 12 physicians and one neuroscientist who signed a letter sent to B.C. Health Minister Josie Osborne calling on treatment to be reinstated, eight of the signatories have declared conflicts in the past five years in papers written for scientific journals or for public presentations because they have consulted for, been paid by, or received grants from California-based BioMarin Pharmaceutical Inc. Another doctor reported being a consultant for BioMarin for four years on a resumé posted online and was paid by BioMarin to be on a medical podcast. Start your day with a roundup of B.C.-focused news and opinion. By signing up you consent to receive the above newsletter from Postmedia Network Inc. A welcome email is on its way. If you don't see it, please check your junk folder. The next issue of Sunrise will soon be in your inbox. Please try again Interested in more newsletters? Browse here. BioMarin manufactures Brineura used to treat Batten disease, the rare incurable neurodegenerative condition that 10-year-old B.C. girl Charleigh Pollock has. Three other doctors who signed the letter have relationships with foundations that advocate and raise money for Batten disease research. The Postmedia examination also found that one of the U.S. doctors that signed the letter owns shares in BioMarin, two have been quoted in BioMarin news releases and three former BioMarin employees sit on one of the U.S.-based Batten research foundations. Experts in bioethics and pharmaceutical policy say the conflict-of-interest revelations raise questions on why the B.C. government overruled its own advisory committee, why it depended on the opinions of U.S. doctors with relationships to BioMarin, and whether it took those conflict-of-interest relationships into consideration. 'I want to suggest that the British Columbia Ministry of Health was handling this case in an ethically justifiable way and has been sidetracked by the lobbying efforts of the Batten disease patient advocacy groups and the patient herself and the doctors whose careers stand to benefit from licensing and prescribing this drug,' said Arthur Schafer, a University of Manitoba professor with a speciality in bioethics and founder of the school's centre for professional and applied ethics. In an emailed statement from communications manager Amy Crofts, the B.C. Ministry of Health said they 'can confirm that government was aware that some of the U.S. experts have conflicts of interest.' Officials noted the conflicts were required to be declared when publishing peer-reviewed research on Batten disease, including the initial clinical trials on Brineura that were funded by BioMarin and used by Canada's Drug Agency in 2019 to establish the discontinuation criteria. Health officials did not respond to questions on whether the government considered the conflicts of interest in their assessment and how it weighed these conflicts against the advice of its own adviser group. Osborne was not made available for an interview. Initially, the B.C. government backed its advisory committee's decision to halt treatment to the 10-year-old girl after six years. The advisory committee said they recommended stopping treatment because discontinuation criteria was met, and beyond which the benefits versus risks of the drug were not believed to be favourable. The U.S. doctors sent a letter — under a Batten disease support and research association designation — outlining their concerns and calling for the girl's treatment to continue. Osborne, the health minister, said the province reversed its decision because of the letter. 'The letter I received today from the Batten disease experts confirms there is a significant disagreement between health experts on Brineura, and it is not acceptable that Charleigh and her family suffer as a result of that disagreement about the use of Brineura for Batten disease,' Osborne said last month. Following the reversal, 10 members of the advisory committee quit and B.C. Premier David Eby has now called for a review and overhaul of the decision process. Schafer, who has been studying biomedical conflicts of interest for more than 20 years, said he was not surprised to learn the U.S. letter signatories had relationships with the drug company that produced the drug and that they recommended its continued use. He said he believes the B.C. government would have been fully aware of the conflicts of interests held by the U.S. doctors who signed the letter, as these relationships are 'standard procedure.' Schafer, who formerly worked as an ethics consultant for the Winnipeg Regional Health Authority, said he believes the B.C. government capitulated and caved to pressure, as he believes most Canadian provincial governments would. 'And I think the resulting decision is not morally justifiable,' he said. Schafer noted the effectiveness of these expensive rare-disease drugs is often unproven, underscoring the importance for governments to have independent expert advice when making difficult decisions in the face of emotion, public pressure and scarce resources. Other experts have made similar observations. Pierre-Marie David, a professor in the faculty of pharmacy at the University of Montreal who has been researching access to exceptional drugs, said a key to making these decisions is building trust in provincial health agencies, particularly given there is a large pipeline of these expensive drugs with uncertain effectiveness for rare diseases, which means more difficult decisions and increasing costs. 'If we have trust in the decision of a public agency, we should stick to it,' said David. He said he did not believe provinces and Canada should be turning for advice to the U.S. health system, whether the doctors there are right or wrong, or have a conflict of interest or not, because they do not have a public health care system like Canada's. 'They have no lessons to tell us here,' said David. The relationships of some of the U.S. letter signatories to BioMarin are laid out in conflict-of-interest and disclosure statements in scientific journals. For example, a 2024 editorial Dr. Raymond Wang wrote for the journal Neurology includes a 'disclosure' that says he receives research funding from, has received speaking honorariums from, and owns equity in BioMarin Pharmaceuticals, which manufacturers Brineura. Wang is director of the Batten Disease Center for Excellence at Children's Hospital of Orange County in California. A 2024 Lancet Neurology journal article co-written by Dr. Emily de los Reyes includes a conflict-of-interest statement that notes she received 'salary support' from BioMarin for herself and her research personnel. She also received honorariums and travel support. De los Reyes is the chair of the Batten Disease Centers of Excellence program and director of the Batten Disease Center of Excellence at Nationwide Children's Hospital in Columbus, Ohio. A 2022 Journal of Inherited Metabolic Disease paper co-authored by Dr. Erika Augustine, who is the director of the Batten Disease Centre of Excellence at the Kennedy Krieger Institute in Baltimore, notes in a conflict-of-interest statement that she received compensation as a consultant for BioMarin and other pharmaceutical companies. Postmedia reached out by email to these doctors to ask questions about the conflict-of-interest disclosures, but did not receive a reply. In a written response to Postmedia questions, Amy Fenton Parker, president of the Batten Disease Support and Research Association, said questions of funding from drug companies should be posed to each research and clinical treatment group. 'In all scientific presentations, both groups are required to make disclosures about any funding or conflicts of interest,' noted Parker. She noted the centres of excellence do not receive funding from industry partners through the association. There are a number of Batten disease organizations that co-operate and partner to advocate for, and help fund, research for treatments. The Batten Disease Support and Research Association manages the centres of excellence program, under which the U.S. doctors who signed the letter operate. That association has three former BioMarin employees on its board of directors , including vice-chair Barbara Wuebbels. Another group, the Beyond Batten Disease Foundation, has raised $35 million to help fund research to find treatments and has partnered with the Batten Disease Support and Research Association. The research association has several chapters around the world, including in Canada. The 10-year-old B.C. girl's mother, Jori Fales, is on the board of directors of the Canadian chapter, according to the latest filing of the group for registered charities in Canada. ghoekstra@


The Market Online
7 hours ago
- The Market Online
Tilray expands access to medical cannabis extracts in Italy
Tilray Medical, a division of cannabis powerhouse Tilray Brands (TSX:TLRY), has partnered with Molteni, an Italian pharmaceutical firm focused on pain therapies and substance dependence, to broaden the availability of its cannabis extracts across Italy Tilray Brands is a cannabis, beverage, wellness and entertainment company supporting more than 40 brands in more than 20 countries Tilray stock has given back 48.03 per cent year-over-year and 93.28 per cent since May 2021 Tilray Medical, a division of cannabis powerhouse Tilray Brands (TSX:TLRY), has partnered with Molteni, a top Italian pharmaceutical firm focused on pain therapies and substance dependence, to broaden the availability of its cannabis extracts across Italy. This content has been prepared as part of a partnership with Tilray Brands Inc., and is intended for informational purposes only. Under the partnership, Tilray Medical subsidiary, FL Group, will provide medical cannabis education throughout Molteni's network of pharmaceutical, scientific and medical professionals in Italy. Founded in 1892 and headquartered in Florence, Molteni maintains operations in more than 40 countries and benefits from in-house manufacturing, research and development, regulatory, supply chain and commercial capabilities, opening the door for future partnerships with Tilray down the line. The new partnership complements Tilray's existing operations in Italy, in addition to presences in Germany, Portugal, Poland and the United Kingdom, with European cannabis revenue growing by 112 per cent in fiscal 2025. Leadership insights 'This partnership reflects our commitment to advancing patient care through strategic collaboration,' Rajnish Ohri, Tilray Brands' Managing Director, International, said in Wednesday's news release. 'By combining FL Group's regulatory and distribution capabilities with Molteni's scientific leadership, we are not only expanding access to high-quality, EU-GMP certified cannabis therapies for patients across Italy but also prioritizing medical cannabis education for pain therapies. Through Molteni's extensive network of healthcare professionals, we aim to empower practitioners with the knowledge and resources needed to support patients seeking effective pain management solutions.' About Tilray Brands Tilray Brands is a cannabis, beverage, wellness and entertainment company supporting more than 40 brands in more than 20 countries. Tilray stock (TSX:TLRY) las traded at C$1.32. The cannabis stock has given back 48.03 per cent year-over-year and 93.28 per cent since May 2021. Join the discussion: Find out what everybody's saying about this Canadian cannabis stock on the Tilray Brands Inc. Bullboard and check out the rest of Stockhouse's stock forums and message boards. Stockhouse does not provide investment advice or recommendations. All investment decisions should be made based on your own research and consultation with a registered investment professional. The issuer is solely responsible for the accuracy of the information contained herein. For full disclaimer information, please click here.


The Market Online
9 hours ago
- The Market Online
200% opportunity NOW: How Novo Nordisk, Dryden Gold, and Puma could boost your portfolio
The stock market in 2025 resembles a chessboard of extremes. While volatility is shaking up markets, extraordinary opportunities are emerging in unexpected corners. Established giants are stumbling, but it is precisely sharp price declines that harbor explosive comeback potential. At the same time, commodity newcomers are catching the attention of investors, driven by a sharp rise in the price of gold. And global consumer brands? Their fundamental strength may surprise despite short-term turbulence. Three very different players perfectly illustrate this momentum: Danish pharmaceutical giant Novo Nordisk, Canadian gold explorer Dryden Gold, and Puma, a German sportswear manufacturer. Their stories could transform your portfolio. This article is disseminated in partnership with Apaton Finance GmbH. It is intended to inform investors and should not be taken as a recommendation or financial advice. Novo Nordisk – Why the slump seems exaggerated Last week, Novo Nordisk reported a stable second quarter. Revenue of DKK 24.2 billion represents an increase of 16% compared to the previous year, and profits also rose by 25%. Despite this robust result, the share price continued to slide, driven by the reduced annual forecast, which now predicts revenue growth of 8-14% instead of 13-21%, and the change of CEO. Market share losses for key products, such as Wegovy, to competitor Eli Lilly and illegal generic drugs were additional burdens. But that is only half the story. People are forgetting how profitable Novo is. Operating profit shot up 86% in the first half of the year, and net profit almost doubled. Wegovy grew by 67% in Q2 alone, exceeding expectations. The long-term potential is crucial. Obesity affects around 40% of US adults, and less than 1% are treated with medication globally. Novo dominates this growth market with its established products and an advanced pipeline, including products such as CagriSema and Amycretin. Lilly's setback with the weak study results for Orforglipron plays into Novo Nordisk's hands. Novo is currently trading at a price-to-earnings ratio (P/E) of around 12 for 2026, well below its three-year average of around 34. In comparison, its competitor Eli Lilly is valued at a P/E ratio of over 22 for the same period. Even with moderate assumptions of 8-10% growth, the valuation appears overly conservative. Even a return to the historical average P/E ratio of 20 would mean significant upside potential based on conservative earnings forecasts. Although high capital expenditure on production capacity is weighing on cash flow in the short term, it will secure market penetration in the long term. The profitable market leader on its growth path is currently available for EUR 42.52. Dryden Gold – Three reasons to pay attention Canadian exploration company Dryden Gold (TSXV:DRY) has significantly expanded its current capital measure. Instead of the originally planned amount, up to CAD 7.8 million will now flow into the coffers through the sale of various types of shares. The high demand underscores the market's interest. Major shareholder Centerra Gold is also securing its 9.9% stake once again through a top-up right. The fresh capital will flow directly into additional drilling in northwestern Ontario and cover operating costs. For investors, the successful capital measure signals clear confidence in the project. Current drilling results from the flagship Gold Rock project confirm the potential. Several high-grade gold discoveries, including 15.3 g/t over 1.45 m and 5.36 g/t over 5 m, reveal a complex system of repeating structures. These are not isolated but extend for approximately 1 km between the Jubilee and Laurentian target areas. Visible gold was even drilled at a depth of 238 m. The combination of high grades and wide distribution is architecturally similar to productive systems such as Red Lake. Dryden strategically controls a consolidated land package of approximately 70,000 ha in an established mining region of Ontario. Proximity to the Trans-Canada Highway and existing infrastructure keep exploration costs unusually low. Partnerships with First Nations minimize operational risks. With the current funding, the fully financed exploration program can progress rapidly and deliver further results in the near term. For investors, this is not a hype-driven story, but a methodical exploration with clear leverage points such as new zones, depth extensions, and confirmed repeatability of high-grade structures. Analysts at Couloir Capital have issued a price target of CAD 0.65. The stock is currently trading at CAD 0.205, offering more than 100% upside potential. Puma has responded to its recent disappointing quarterly figures. The new key managers are addressing core problems: Former Adidas CIO Andreas Hubert is taking over as COO of the supply chain, bringing with him 12 years of expertise in Asia. This should be crucial for the 'nextlevel' cost-cutting program. Basketball Vice President Archie McEachern, a former Nike manager, is to reposition the lucrative US streetwear division. At the same time, CEO Arthur Höld is demonstrating his confidence in the turnaround by purchasing over EUR 100,000 worth of shares and another EUR 110,000 worth of derivatives on Puma. These targeted appointments directly address the sore points of margin pressure and innovation gaps. The direct-to-consumer (DTC) segment, which is already growing at double-digit rates, up 9.2% in the second quarter with online sales up 19.4%, is becoming a margin lever. Every percentage point increase in the DTC share from the current 31% boosts profitability without wholesale discounts. At the same time, the Company is pushing ahead with its premium strategy. Speedcat sneakers featuring K-pop star Rosé are already achieving high sales figures in Asia and Europe. If Puma manages to increase its DTC share to 40%, roughly the same level as Nike, and anchor its premium positioning in running/basketball, EBIT margins of 8–10% are entirely realistic. The stock is trading at a value of 5.3x EV/EBITDA, compared to around 14x for Adidas and approximately 24x for Nike. Even with moderate assumptions such as a slight recovery in sales in 2026 and a margin of 7%, a re-rating to 8–10x EV/EBITDA appears plausible. That alone implies significant upside potential. The free cash flow yield of a good 13% also offers flexibility. With declining inventory costs and reduced capital expenditures now at EUR 250 million, Puma could either reduce its debt or buy back shares. The share is currently available for EUR 17.255, which is below the price paid by the Management Board. Market volatility in 2025 is opening up selective opportunities for bold investors. Despite short-term setbacks and a valuation correction, Novo Nordisk offers massive long-term growth potential in the profitable obesity market at a favorable P/E ratio. Dryden Gold impresses with strong drilling results, a strategic project location, and fresh capital, which will enable accelerated exploration with significant upside potential relative to the current price. Puma is setting clear levers for a higher-margin recovery with new personnel and a focus on DTC growth and a premium strategy, with the stock appearing extremely undervalued. Diversified, all three offer interesting opportunities, albeit with varying degrees of risk. Conflict of interest Pursuant to §85 of the German Securities Trading Act (WpHG), we point out that Apaton Finance GmbH as well as partners, authors or employees of Apaton Finance GmbH (hereinafter referred to as 'Relevant Persons') may hold shares or other financial instruments of the aforementioned companies in the future or may bet on rising or falling prices and thus a conflict of interest may arise in the future. The Relevant Persons reserve the right to buy or sell shares or other financial instruments of the Company at any time (hereinafter each a 'Transaction'). Transactions may, under certain circumstances, influence the respective price of the shares or other financial instruments of the Company. In addition, Apaton Finance GmbH is active in the context of the preparation and publication of the reporting in paid contractual relationships. For this reason, there is a concrete conflict of interest. The above information on existing conflicts of interest applies to all types and forms of publication used by Apaton Finance GmbH for publications on companies. Risk notice Apaton Finance GmbH offers editors, agencies and companies the opportunity to publish commentaries, interviews, summaries, news and the like on These contents are exclusively for the information of the readers and do not represent any call to action or recommendations, neither explicitly nor implicitly they are to be understood as an assurance of possible price developments. The contents do not replace individual expert investment advice and do not constitute an offer to sell the discussed share(s) or other financial instruments, nor an invitation to buy or sell such. The content is expressly not a financial analysis, but a journalistic or advertising text. Readers or users who make investment decisions or carry out transactions on the basis of the information provided here do so entirely at their own risk. No contractual relationship is established between Apaton Finance GmbH and its readers or the users of its offers, as our information only refers to the company and not to the investment decision of the reader or user. The acquisition of financial instruments involves high risks, which can lead to the total loss of the invested capital. The information published by Apaton Finance GmbH and its authors is based on careful research. Nevertheless, no liability is assumed for financial losses or a content-related guarantee for the topicality, correctness, appropriateness and completeness of the content provided here. Please also note our Terms of use. Stockhouse does not provide investment advice or recommendations. All investment decisions should be made based on your own research and consultation with a registered investment professional. The issuer is solely responsible for the accuracy of the information contained herein. For full disclaimer information, please click here .