NASA Astronaut Don Pettit, Crewmates Complete Space Station Expedition
WASHINGTON, April 19, 2025 /PRNewswire/ -- NASA astronaut Don Pettit returned to Earth Saturday, accompanied by Roscosmos cosmonauts Alexey Ovchinin and Ivan Vagner, concluding a seven-month science mission aboard the International Space Station.
The trio departed the space station at 5:57 p.m. EDT aboard the Soyuz MS-26 spacecraft before making a safe, parachute-assisted landing at 9:20 p.m. (6:20 a.m. on Sunday, April 20, Kazakhstan time), southeast of Dzhezkazgan, Kazakhstan. Pettit also celebrates his 70th birthday on Sunday, April 20.
Spanning 220 days in space, Pettit and his crewmates orbited the Earth 3,520 times, completing a journey of 93.3 million miles. Pettit, Ovchinin, and Vagner launched and docked to the orbiting laboratory on Sept. 11, 2024.
During his time aboard the space station, Pettit conducted research to enhance in-orbit metal 3D printing capabilities, advance water sanitization technologies, explore plant growth under varying water conditions, and investigate fire behavior in microgravity, all contributing to future space missions. He also used his surroundings aboard station to conduct unique experiments in his spare time and captivate the public with his photography.
This was Pettit's fourth spaceflight, where he served as a flight engineer for Expeditions 71 and 72. He has logged 590 days in orbit throughout his career. Ovchinin completed his fourth flight, totaling 595 days, and Vagner has earned an overall total of 416 days in space during two spaceflights.
NASA is following its routine postlanding medical checks, the crew will return to the recovery staging area in Karaganda, Kazakhstan. Pettit will then board a NASA plane bound for the agency's Johnson Space Center in Houston. According to NASA officials at the landing site, Pettit is doing well and in the range of what is expected for him following return to Earth.
For more than two decades, people have lived and worked continuously aboard the International Space Station, advancing scientific knowledge and making research breakthroughs that are not possible on Earth. The station is a critical testbed for NASA to understand and overcome the challenges of long-duration spaceflight and to expand commercial opportunities in low Earth orbit. As commercial companies focus on providing human space transportation services and destinations as part of a strong low Earth orbit economy, NASA is focusing more resources on deep space missions to the Moon as part of Artemis in preparation for future astronaut missions to Mars.
Learn more about International Space Station research and operations at:
https://www.nasa.gov/station
View original content to download multimedia: https://www.prnewswire.com/news-releases/nasa-astronaut-don-pettit-crewmates-complete-space-station-expedition-302432990.html
SOURCE NASA

Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles


Bloomberg
15 minutes ago
- Bloomberg
Bloomberg Businessweek Daily: Musk Ally Out At NASA
President Donald Trump said he would name a new nominee for NASA administrator, just days before billionaire Jared Isaacman, the current pick and a close ally of Elon Musk, was to face his planned Senate confirmation vote. It wasn't immediately clear why Trump was dropping the nomination of Isaacman, who had already been approved by the Senate Commerce Committee. Trump posted on Truth Social that he made the decision after a 'thorough review of prior associations.' Bloomberg News Space Reporter Loren Grush details the fallout from Trump's decision and discusses what comes next for the space agency.
Yahoo
an hour ago
- Yahoo
Angelman Syndrome Market to Witness Significant Growth Through 2034, Driven by Novel Therapeutic Advancements
According to DelveInsight's estimates, the Angelman syndrome market size in the 7MM is expected to show positive growth during the forecast period (2025–2034), primarily driven by the increasing prevalence of Angelman syndrome, growing awareness and diagnosis, and new product launches. LAS VEGAS, June 2, 2025 /PRNewswire/ -- Angelman syndrome is a rare neurogenetic disorder affecting approximately 1 in 15,000 live births or 500,000 people globally. It results from the loss of function of the UBE3A gene located on the 15th chromosome, specifically the copy inherited from the mother. This loss is typically caused by a deletion or mutation of the UBE3A gene, leading to a deficiency of functional UBE3A protein in the brain. The condition is typically identified by developmental delays that become apparent between 6 and 12 months of age. Both males and females are equally affected, with the Angelman syndrome prevalence estimated to be about 1 in 12,000 to 20,000 people in the general population. In the US, the Angelman syndrome epidemiology is characterized by a diverse landscape. While rare, the Angelman syndrome prevalence is expected to rise due to improvements in diagnostic techniques, expanded availability of genetic testing, and greater awareness among healthcare professionals and the general public. This condition presents with developmental delays, intellectual disabilities, significant speech impairments, and distinct behavioral traits. As Angelman syndrome treatment options improve, along with advancements in supportive services and increased life expectancy for those affected, the number of individuals diagnosed is anticipated to grow. This evolving landscape highlights the importance of continued research, early detection, and comprehensive care to better support individuals with Angelman syndrome and their families. Learn more about the Angelman syndrome epidemiology @ Angelman Syndrome Cases Current treatment approaches for Angelman syndrome focus on a comprehensive, multidisciplinary strategy to manage symptoms and improve quality of life. Although there is no cure, treatments like antiepileptic drugs for seizure control and behavioral therapies are key in symptom management. Augmentative and alternative communication methods, alongside physical and occupational therapy, address developmental delays and enhance functional skills. Support services, including special education and support groups, provide vital assistance for individuals and families affected by Angelman syndrome. Current research on Angelman syndrome into experimental therapies, such as gene therapy and targeted drug treatments, offers promise for future breakthroughs in managing the condition. Angelman syndrome medications like RISPERDAL (risperidone) may help control hyperactive and socially disruptive behaviors, but should not be used long-term. Acid reflux (gastroesophageal reflux) is common in individuals with Angelman syndrome and can be managed by keeping the person upright during and after meals or using Angelman syndrome medications like Gaviscon and ranitidine. In severe, rare cases, a surgical procedure called fundoplication may be necessary. While current Angelman syndrome treatments focus on managing symptoms, there is a significant need for disease-modifying therapies that address the underlying genetic cause of Angelman syndrome, such as gene therapy or UBE3A reactivation strategies. Find out more about Angelman syndrome therapy @ Angelman Syndrome Medication Despite available antiepileptic Angelman syndrome medications, many individuals with Angelman syndrome experience treatment-resistant seizures, highlighting the need for more effective seizure management options. While augmentative and alternative communication (AAC) methods are helpful, there is a need for more advanced and accessible communication aids to improve communication abilities in non-verbal individuals. There is a need for long-term support services to address the evolving needs of individuals with Angelman syndrome as they transition into adulthood, including vocational training, independent living support, and access to specialized healthcare services. The pipeline of emerging treatments for Angelman syndrome shows promise, with mid-late stage products such as Ionis Pharmaceuticals' ION582, Ultragenyx Pharmaceuticals' GTX-102, Neuren Pharmaceuticals' NNZ-2591, MavriX Bio's MVX-220, and others demonstrating the potential to significantly impact the Angelman syndrome market and potentially revolutionize the treatment approach. Discover which Angelman syndrome therapy will grab major market share @ Angelman Syndrome Medical Research ION582 is an experimental antisense drug aimed at inhibiting the UBE3A transcript (UBE3A-ATS) and enhancing the production of UBE3A protein, potentially offering a treatment for Angelman syndrome. In July 2024, Ionis Pharmaceuticals reported positive outcomes from the HALOS Phase I/II study of ION582 in Angelman syndrome. Notable improvements were observed in communication, cognition, and motor function, with 97% of participants in the medium and high-dose groups showing overall symptom improvement based on SAS-CGI-C assessments. Ionis plans to start Phase III development in the first half of 2025. In May 2024, Ionis revealed positive topline results from the HALOS Phase I/IIa open-label study of ION582 in Angelman syndrome and announced that it would independently advance ION582 as part of its portfolio of potentially transformative treatments for serious neurological conditions. The company also plans to consult with regulatory authorities on the design of a pivotal program. Biogen chose not to exercise its option to license ION582. In 2022, the US FDA and EMA granted Orphan Drug Designation to ION582, and the FDA also awarded Fast Track and Rare Pediatric Designation. The drug is currently in Phase II trials and progressing toward Phase III. GTX-102 is an experimental antisense oligonucleotide delivered via intrathecal administration, targeting and inhibiting the expression of UBE3A-AS. Preclinical studies suggest that GTX-102 reduces UBE3A-AS levels and reactivates the paternal UBE3A allele in CNS neurons. GTX-102 has received Orphan Drug Designation, Rare Pediatric Disease Designation, and Fast Track Designation from the FDA, as well as Orphan Designation and PRIME designation from the EMA. In July 2024, Ultragenyx Pharmaceuticals presented new data and regulatory updates on GTX-102 at the ASF Conference, reviewing Phase I/II results and outlining plans to begin Phase III trials by the end of the year. In August 2019, GeneTx and Ultragenyx formed a partnership to develop GTX-102, with Ultragenyx acquiring exclusive rights to GeneTx in July 2022 for an initial payment of USD 75 million, plus future milestone and royalty payments. In April 2024, Ultragenyx announced positive interim Phase I/II data in Angelman syndrome patients treated with GTX-102. The drug is currently in Phase III trials. NNZ-2591 is an enhanced synthetic version of a naturally occurring brain peptide related to IGF-1, a growth factor stimulated by growth hormone. The drug is being developed to treat Angelman syndrome by restoring the natural balance of brain function. Neuren has received Orphan Drug Designation for NNZ-2591 from both the US FDA and EMA. The company has recently completed a Phase II clinical trial for Angelman syndrome. In August 2024, Neuren released positive top-line results from its Phase II trial, showing that the drug was safe and well-tolerated, with no serious adverse events. Furthermore, significant improvements were observed in both clinician and caregiver global efficacy measures tailored to the disease. MVX-220 is an experimental gene therapy based on the hu68AAV vector, developed to deliver the human UBE3A gene directly to brain neurons through a single intra-cisterna magna (ICM) injection. In preclinical studies, it has demonstrated the ability to restore UBE3A protein levels and alleviate symptoms in mouse models of Angelman syndrome. The therapy will be assessed in the Phase I/II clinical trial known as ASCEND-AS (AAV-mediated expression in neurons for Angelman syndrome). In May 2025, MavriX Bio announced that the FDA approved its Investigational New Drug (IND) application for MVX-220. The company plans to begin the first-in-human (FIH) ASCEND-AS clinical trial in the second half of 2025. To know about what is the current status of research on Angelman syndrome, visit @ Angelman Syndrome Cure Research The anticipated launch of these emerging therapies for Angelman syndrome are poised to transform the market landscape in the coming years. As these cutting-edge therapies continue to mature and gain regulatory approval, they are expected to reshape the Angelman syndrome market landscape, offering new standards of care and unlocking opportunities for medical innovation and economic growth. DelveInsight estimates that the market size for Angelman syndrome is expected to grow at a significant CAGR by 2034. This growth is mainly attributed to the increasing prevalence of Angelman syndrome, growing awareness and diagnoses, and the new product launches. DelveInsight's latest published market report, titled as Angelman Syndrome Market Insight, Epidemiology, and Market Forecast – 2034, will help you to discover which market leader is going to capture the largest market share. The report provides comprehensive insights into the Angelman syndrome country-specific treatment guidelines, patient pool analysis, and epidemiology forecast to help understand the key opportunities and assess the market's underlying potential. The Angelman syndrome market report proffers epidemiological analysis for the study period 2020–2034 in the 7MM segmented into: Total Prevalence of Angelman Syndrome Total Diagnosed Prevalence of Angelman Syndrome Angelman Syndrome Cases Associated with Clinical Manifestations Treated Cases of Angelman Syndrome The report provides an edge while developing business strategies by understanding trends shaping and driving the 7MM Angelman syndrome market. Highlights include: 10-year Forecast 7MM Analysis Epidemiology-based Market Forecasting Historical and Forecasted Market Analysis upto 2034 Emerging Drug Market Uptake Peak Sales Analysis Key Cross Competition Analysis Industry Expert's Opinion Access and Reimbursement Download this Angelman syndrome market report to assess the epidemiology forecasts, understand the patient journeys, know KOLs' opinions about the upcoming treatment paradigms, and determine the factors contributing to the shift in the Angelman syndrome market. Also, stay abreast of the mitigating factors to improve your market position in the Angelman syndrome therapeutic space. Related Reports Angelman Syndrome Epidemiology Forecast Angelman Syndrome Epidemiology Forecast – 2034 report delivers an in-depth understanding of the disease, historical and forecasted Angelman syndrome epidemiology in the 7MM, i.e., the United States, EU5 (Germany, Spain, Italy, France, and the United Kingdom), and Japan. Angelman Syndrome Pipeline Angelman Syndrome Pipeline Insight – 2025 report provides comprehensive insights about the pipeline landscape, pipeline drug profiles, including clinical and non-clinical stage products, and the key Angelman syndrome companies, including Neuren Pharmaceuticals, Ultragenyx Pharmaceutical, Ionis Pharmaceuticals, Roche, GEXVal, PTC Therapeutics, Taysha Gene Therapies, Ovid Therapeutics, among others. Rett Syndrome Market Rett Syndrome Market Insights, Epidemiology, and Market Forecast – 2034 report delivers an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the market trends, market drivers, market barriers, and key Rett syndrome companies, including Biomed Industries, NEUROGENE, Taysha Gene Therapies, Anavex Lifesciences, among others. Rett Syndrome Pipeline Rett Syndrome Pipeline Insight – 2025 report provides comprehensive insights about the pipeline landscape, pipeline drug profiles, including clinical and non-clinical stage products, and the key Rett syndrome companies, including Anavex Life Sciences Corp, Neurogene, Taysha GTx, among others. About DelveInsight DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports pharma companies by providing comprehensive end-to-end solutions to improve their performance. Get hassle-free access to all the healthcare and pharma market research reports through our subscription-based platform PharmDelve. Contact UsShruti Thakur info@ +14699457679 Logo: View original content: SOURCE DelveInsight Business Research, LLP

Yahoo
an hour ago
- Yahoo
Project Beep, a confidential airspace firm, to lease land for $247M Merritt Island facility
Space Florida has authorized leasing 25 acres on northern Merritt Island for Project Beep, an undisclosed aerospace company that plans to build a future quarter-billion-dollar facility and create about 1,000 jobs just outside NASA's Kennedy Space Center. Little information has been publicly released about this confidential company. "It captures the increasing pace of activity around the world's busiest spaceport," Space Florida President and CEO Rob Long said during the authority's May 28 board of directors meeting. "Obviously, we welcome this growth and are excited about the bright future for the space industry here in Florida." By unanimous vote, Space Florida authorized completion of negotiations for a 30-year Project Beep lease for the last two remaining parcels of the opening phase of Exploration Park, which is managed in partnership with NASA. "Project Beep intends to set up manufacturing, research and development, laboratory, warehousing and office facilities to support aerospace operation at Cape Canaveral Spaceport," said Howard Haug, Space Florida executive vice president, treasurer and chief investment officer. "The project estimates total investment of $247 million and expects creating approximately 1,000 jobs at industry-average wages." During a post-meeting press conference, Long said Project Beep officials are still looking at building structural designs, and Space Florida will work with the mystery company on that topic during the next several months. Statewide, Space Florida reported it is pursuing 204 business opportunities. The Space Coast leads the way with 51 potential deals, followed by Central Florida with 28 opportunities and the western Panhandle with 24. The Space Florida meeting kicked off 3½ hours after SpaceX launched a Falcon 9 rocket from NASA's Kennedy Space Center into low-Earth orbit on another Starlink mission. The liftoff marked the 45th orbital rocket launch thus far this year from Florida's Space Coast. For the latest news from Cape Canaveral Space Force Station and NASA's Kennedy Space Center, visit Another easy way: Click here to sign up for our weekly Space newsletter. Rick Neale is a Space Reporter at FLORIDA TODAY. Contact Neale at Rneale@ Twitter/X: @RickNeale1 Space is important to us and that's why we're working to bring you top coverage of the industry and Florida launches. Journalism like this takes time and resources. Please support it with a subscription here. This article originally appeared on Florida Today: Space Florida to lease land for Project Beep aerospace firm, 1,000 jobs