Revolutionize Your Health Routine With New NAD+ Patches
It's 2025, and NAD+ is to wellness as pilates is to working out. NAD+ is a naturally occurring coenzyme in your body that's in charge of energy metabolism, DNA repair, and even stem cell rejuvenation. Celebrities like Hailey Bieber, Kendall Jenner, and Gwyneth Paltrow swear by it, often hooking themselves up to NAD+ IVs. It's available in pill form and various elixirs as a supplement, but now, thanks to Barrière and their innovative vitamin patches, you'll be able to get it into your system via a cute little sticker.
Since NAD+ has so many alleged benefits, including boosting metabolism and improving cognitive function, it sounds like something we should ideally all be able to get at any time. But to reap the benefits of NAD+, the most potent option is an IV drip, and it comes with red tape; it can cost anywhere between $300 to $2,000 for a typical 500 mg dose, and it is a slow process that takes anywhere from two to four hours. Speeding up an NAD+ IV can be painful (Joe Rogan described a quicker NAD+ infusion as 'excruciating' on his podcast), and regardless of how long it takes, any NAD+ drip can cause side effects like vomiting, nausea, dizziness, flushing, or redness. 'I am not a fan of IVs because I think they give you too much at once, and your body doesn't really know what to do with that high of a dose,' says Amanda Kahn, MD, a longevity doctor who recommends shots instead of IVs.
Shots can still be difficult to get, and they're as expensive as infusions, so many people are still on the hunt for other routes. Oral supplements have shown some promise, but there's limited data, according to a 2023 study in The Journals of Gerontology: Series A. The study found that, overall, oral supplements that use NAD+ precursors have shown to be safe, well-tolerated, and may boost overall NAD+ levels in the body. But if you don't want to take another pill, a patch may be the best option.
'Barrière's NAD+ patch uses a transdermal delivery system to gently release NAD+ through the skin over time, allowing for consistent absorption directly into the bloodstream,' says Sogol Ash, MD and medical advisor to Barrière. 'It bypasses the digestive system and liver, which makes it ideal for people who want a non-invasive, on-the-go option to boost NAD+ levels without needing an IV or capsule.'
Barrière co-founder Cleo Davis-Urman says she wanted to make the patch as a more accessible option, using NR, a precursor to NAD+ that converts to the peptide once it's in your system. 'The goal of the patch is to replenish declining NAD levels so that your body starts to produce more on its own,' she says. 'It supports cellular energy production, metabolic health, healthy aging, muscle recovery, cognitive function, and more. I call it a fountain of youth.'
The patch also closely mimics the delivery system of an IV treatment, though it delivers far less at once. You'll apply two small patches, which have a total of 18 mg of NR, every other day. 'This follows the recommended treatment using IV therapies,' Davis-Urman says. 'It gives your body a day of rest in between, which is scientifically studied to be more beneficial.'
And thanks to its unique delivery method, Davis-Urman says the patch also doesn't come with the same unpleasant side effects as IVs or oral supplements. 'IVs can shock your system, while oral supplements can cause nausea as your body acclimates to the peptide. The slow transdermal delivery is letting your body, over eight to 12 hours, get a small and consistent dose,' Davis-Urman says.
As for how much NAD+ is actually getting in your system? The jury's still out, since there's no real way to measure it; you can't tell in a blood test like you would for something like vitamin D, though Ash says that tests are currently being developed. 'In the meantime, I test downstream effects through functional labs, including improvements in mitochondrial markers, inflammation, and shifts in biological age,' she says. 'But the most meaningful feedback often comes from how someone actually feels. Many people notice real improvements in energy, sleep quality, mental clarity, and recovery within just a few weeks of consistent patch use.'
Keep in mind that if you want the most benefit out of NAD+, an IV is still the best option, according to Alexander GolBerg, MD, DO, who calls it the 'Rolls-Royce' of ways to get NAD+ into your system. 'In the patch, they don't know how much is absorbed,' he cautions. Still, doctors agree that patches like Barrière's are low risk, so we're willing to stick some on to find out the benefits for ourselves.
Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles
Entrepreneur
a day ago
- Entrepreneur
What's Really Inside Your Supplements? This Founder Is Uncovering the Truth Behind the $180 Billion Industry
From creatine to NAD+, this company is uncovering the truth behind mislabeled, underdosed and overhyped products. Opinions expressed by Entrepreneur contributors are their own. I recently wrote about creatine and profiled Jeff Byers, co-founder of Momentous, for a reason: integrity matters. When it comes to what we put in our bodies, especially for entrepreneurs aiming to optimize energy, recovery and longevity, founders and consumers deserve transparency and truth. And yet, the supplement industry is booming with very little of either. We're in the middle of a health optimization gold rush. Creatine gummies, NAD+ capsules, sleep pills and brain-boosting stacks are everywhere. Scroll Instagram, walk into Erewhon or search Amazon, and you'll find thousands of options. The global supplement industry is growing fast and is expected to top $240 billion by 2028, yet many of these products do not contain what they claim to. You may be spending $30, $50 or $90 on a supplement and getting barely a trace of the active ingredient, or in some cases, nothing at all. Unlike pharmaceuticals, supplements don't require FDA approval before hitting the market. That creates a loophole where products can launch quickly, and claims, unless dangerously false, go largely unchecked. And it's not just obscure or small brands. Some of the top-selling supplements on Amazon are underdelivering, misleading or worse. That's where Steve Martocci and SuppCo come in. Martocci, best known for founding the music-tech platform Splice, is now on a mission to fix one of the most frustrating problems in wellness: a lack of transparency. SuppCo is a health tech startup that independently tests supplements and publishes public reports that give consumers one thing the industry often avoids: truth. CEO and Co-Founder, Martocci, struggled with his health for most of his life, reaching nearly 300 pounds despite playing three sports and training consistently. Martocci said to me, "Traditional medicine failed me. I remember being told my labs were on the 'low end of normal' and that nothing could be done. It was completely disheartening." After selling GroupMe to Skype, Martocci discovered functional medicine and began working with a doctor on a tailored supplement stack. He lost nearly 100 pounds over the next year and realized that even though supplements had become mainstream, there was no software actually to help people navigate this space. The supplement industry is a $180 billion market, yet it's filled with confusion, noise and a multitude of products that don't deliver what they promise. With SuppCo, Martocci is on a mission to transform how people discover, manage and optimize their supplement routines. Join top CEOs, founders and operators at the Level Up conference to unlock strategies for scaling your business, boosting revenue and building sustainable success. I was introduced to SuppCo's work through their recent Creatine Gummies Report. Creatine, which I personally take and have written about, is one of the most well-researched supplements for both brain and physical performance. But not all products are created equal. SuppCo tested five popular creatine gummy brands sold on Amazon. Only two passed. One contained less than 25% of the labeled amount. SuppCo recently published a report on NAD+ supplements, a trending ingredient in the longevity and cellular energy space, which tested nine products and was even more revealing. 4 passed (Double Wood, Rho Nutrition Liposomal, NatureBell and Thinbi), with Thinbi exceeding its claim at 103%. 5 failed, including Maripolio, which showed 0% of its claimed NAD+. Others tested at less than 3% of the listed amount on the label. NAD+ was the perfect follow-up to the creatine testing series because it represents everything confusing about the supplement space right now. Martocci explained that NAD+ is one of the fastest-rising compounds in longevity and biohacking, endorsed by scientists and influencers, but it's also one of the most confusing for consumers. Martocci said, "You can supplement with NAD+ itself or its precursors like NR and NMN, and most consumers don't understand the bioavailability differences between the three and that one of them is distinctly worse." When we see brands cutting corners on things we can measure, like certifications and testing transparency, they're usually cutting corners on things we can't see too, like what's actually in the bottle. As NAD+ continues to trend for its role in cellular repair and longevity, the gap between marketing and reality becomes even more concerning. Related: Why Top Entrepreneurs Are Swapping Beach Vacations for Longevity Retreats If you're a wellness founder, product integrity is not just a checkbox. It is the heartbeat of your brand. Jeff Byers' company, Momentous, invests in clinical research and testing not because it is required, but because it is what builds lasting trust. Byers told me, "That means showing the science, backing it up with testing, and being radically transparent with our consumers." The next generation of wellness brands will not win on hype. They'll win on data. Consumers are becoming smarter and more demanding, and they want to see the data. SuppCo has already rated over 700 brands and 22,000+ products, and their TrustScore has become remarkably predictive of testing. Now, quality brands are reaching out not just to request a TrustScore, but to get feedback on how to improve their quality practices. When choosing supplements, most people go wrong by treating supplements as if they were all the same. For example, they'll buy the cheapest magnesium without realizing that magnesium oxide has terrible bioavailability compared to magnesium glycinate. Or they'll choose a multivitamin based on how many vitamins are crammed into it, not whether those forms and doses actually work together. Jenna Stangland, co-founder of A4 health and Dietitian for the Minnesota Timberwolves and Minnesota Wild, explains how important it is to ensure that a supplement is tested and validated, as most likely, the dose on the label may not match what is in the bottle and even worse, it could be contaminated. Stangland personally takes NAD+ regularly to support her own energy and help her body adapt to stress and inflammation as she's on airplanes and traveling with teams multiple times per week. Having only tested the creatine and NAD+ categories, SuppCo is just getting started. The company plans to test every major supplement category where there's confusion or questionable quality. This includes protein, magnesium, pre-workouts and nootropics — anywhere consumers are making decisions based on incomplete information, their aim is to bring transparency. Related: Are Your Employees Stressed? You Need to Embrace Transparency. A big milestone they hit recently is the launch of SuppCo Pro, a premium subscription that unlocks deep personalization features. They have received strong user response to their Personal Nutrient Plan, which creates tailored supplement recommendations based on a user's specific goals, as well as their Product Optimizer, which suggests higher-quality, better-value alternatives to what a user is currently taking. This is where the real magic happens, as they can offer truly personalized guidance. I personally appreciate how easy it is to understand their public reports. On the app, you can quickly see whether a product passed or failed, and why. They even launched a browser extension that flags whether the supplement you're browsing has been independently tested. For those of us who care deeply about healthspan, recovery and long-term performance, this kind of transparency is a game-changer.
Yahoo
6 days ago
- Yahoo
James Van Der Beek reveals what colorectal cancer taught him about self-love
James Van Der Beek has just woken up from a nap as he hops on a Microsoft Teams call. About nine months after sharing his colorectal cancer diagnosis with the world, the 48-year-old actor's face looks thinner. He isn't shy talking about the toll his illness has taken on him. He admits he doesn't have as much energy as he used to. He has good days and bad days. But, while he wouldn't wish his illness on anyone, the actor adds it's also given him something else, something he didn't expect: a deeper sense of self-love. "Cancer's a wild thing," he says. "It really does force you to look at your own mortality and decide what's important and decide really what you want to live the rest of your life without. And so, one of the big things for me was recognizing how negative my self-talk was." He continues: "When I was getting treatment and away from the beautiful cacophony of six kids and 36 acres and five dogs and a bearded dragon and the beautiful chaos that is my life, in the quiet I realized how negatively I was talking to myself. And so, that started a whole journey of just recognizing how important self-love is and how necessary and how simple it is." James Van Der Beek and how cancer has changed him Van Der Beek first revealed he had colorectal cancer in a November interview with People, sharing he was diagnosed in August 2023. He says his cancer was detected via colonoscopy. Now, he's partnering with Guardant Health to encourage people to get screened for cancer regardless of if they have symptoms or not. Doing so, he says, is often life-saving. It was for him. What health & wellness means for you: Sign up for USA TODAY's Better Yet newsletter "To me, the biggest misunderstanding is that you need to have symptoms to get screened," he says. "I was very healthy, in amazing cardiovascular shape, and had full-blown stage three cancer, and I didn't know it." The actor says cancer has forced him to take a good, hard look at his life. It's made him rethink what matters and let go of what doesn't. It's also made him reexamine who he really is, versus what he's come to identify himself as. "I was forced to look at myself and say, 'Well, what am I, if I'm just a too skinny guy alone in a room with cancer?' And the conclusion that I came to, after some meditation, was I'm still worthy of love. I'm still worthy of God's love, but I'm still worthy of self-love, just for existing," he says. "My conclusion is that I do believe we're here to experience love − to connect to and to give and to receive love. But, in order to receive love, I think you have to have it for yourself first." Why he wants to work now more than ever Van Der Beek has refused to let cancer stop him from acting. In fact, he says, it's actually fueled him to act − and do other things he loves − even more. Van Der Beek recently appeared in Amazon's "Overcompensating" and is set to also appear in the upcoming "Legally Blonde" spin-off series "Elle." Before cancer, Van Der Beek says, he was on the verge of taking a step back from acting. Since his diagnosis, however, he's recommitted himself to it. "For a minute I thought, 'You know what? I don't need acting. I don't need it in the way that I did before,' " he says. "I'm very, very happy just doing this here with my family. And then, when I got cancer, I realized I love to tell stories. Acting is actually a real passion. Writing is a real passion, and I need to feed that. So, I joke that I'm the only guy I know who got cancer and realized I need to work more." More: James Van Der Beek chokes up discussing his wife's support after cancer diagnosis One of the best parts about acting, he says, is that, when the camera's rolling, nothing else matters. You're in the moment, not thinking about anything else − including cancer. As for family life, Van Der Beek says his kids have all processed his illness differently. The actor and his wife Kimberly Brook share six children, whose ages span 3 to 14. When it comes to parenting with an illness, Van Der Beek has made honesty his policy. Being transparent, he says, has "really allowed for some lovely moments of connection" with his kids. James Van Der Beek, Jenna Fischer and the rise of young people getting cancer "We made the choice to just be as honest as we can with them," he says. "They all handle it differently. They all hide it differently. Their concern manifests differently in each of them. But again, telling them what I'm going through, it actually allows them to show up for me in a way that's just been so beautiful. 'Dad, can I get you tea?' 'No, dad, I'll get that for you.' 'How are you feeling today?' They know when I'm having a bad day. I mean, kids, they pick up on everything." Though he's grateful for the new perspective cancer's given him, he obviously wishes we lived in a world where no one had to go through it. That's why he's "shouting from the rooftops: Get screened. Talk to your doctor." "I'm feeling good," he says. "I've learned a lot. But, if I could save people from having to go through this journey, I definitely will. I would still give colorectal cancer zero stars." This article originally appeared on USA TODAY: James Van Der Beek gives update on colorectal cancer
USA Today
6 days ago
- USA Today
James Van Der Beek reveals what colorectal cancer taught him about self-love
James Van Der Beek has just woken up from a nap as he hops on a Microsoft Teams call. About nine months after sharing his colorectal cancer diagnosis with the world, the 48-year-old actor's face looks thinner. He isn't shy talking about the toll his illness has taken on him. He admits he doesn't have as much energy as he used to. He has good days and bad days. But, while he wouldn't wish his illness on anyone, the actor adds it's also given him something else, something he didn't expect: a deeper sense of self-love. "Cancer's a wild thing," he says. "It really does force you to look at your own mortality and decide what's important and decide really what you want to live the rest of your life without. And so, one of the big things for me was recognizing how negative my self-talk was." He continues: "When I was getting treatment and away from the beautiful cacophony of six kids and 36 acres and five dogs and a bearded dragon and the beautiful chaos that is my life, in the quiet I realized how negatively I was talking to myself. And so, that started a whole journey of just recognizing how important self-love is and how necessary and how simple it is." James Van Der Beek and how cancer has changed him Van Der Beek first revealed he had colorectal cancer in a November interview with People, sharing he was diagnosed in August 2023. He says his cancer was detected via colonoscopy. Now, he's partnering with Guardant Health to encourage people to get screened for cancer regardless of if they have symptoms or not. Doing so, he says, is often life-saving. It was for him. What health & wellness means for you: Sign up for USA TODAY's Better Yet newsletter "To me, the biggest misunderstanding is that you need to have symptoms to get screened," he says. "I was very healthy, in amazing cardiovascular shape, and had full-blown stage three cancer, and I didn't know it." The actor says cancer has forced him to take a good, hard look at his life. It's made him rethink what matters and let go of what doesn't. It's also made him reexamine who he really is, versus what he's come to identify himself as. "I was forced to look at myself and say, 'Well, what am I, if I'm just a too skinny guy alone in a room with cancer?' And the conclusion that I came to, after some meditation, was I'm still worthy of love. I'm still worthy of God's love, but I'm still worthy of self-love, just for existing," he says. "My conclusion is that I do believe we're here to experience love − to connect to and to give and to receive love. But, in order to receive love, I think you have to have it for yourself first." Why he wants to work now more than ever Van Der Beek has refused to let cancer stop him from acting. In fact, he says, it's actually fueled him to act − and do other things he loves − even more. Van Der Beek recently appeared in Amazon's "Overcompensating" and is set to also appear in the upcoming "Legally Blonde" spin-off series "Elle." Before cancer, Van Der Beek says, he was on the verge of taking a step back from acting. Since his diagnosis, however, he's recommitted himself to it. "For a minute I thought, 'You know what? I don't need acting. I don't need it in the way that I did before,' " he says. "I'm very, very happy just doing this here with my family. And then, when I got cancer, I realized I love to tell stories. Acting is actually a real passion. Writing is a real passion, and I need to feed that. So, I joke that I'm the only guy I know who got cancer and realized I need to work more." More: James Van Der Beek chokes up discussing his wife's support after cancer diagnosis One of the best parts about acting, he says, is that, when the camera's rolling, nothing else matters. You're in the moment, not thinking about anything else − including cancer. As for family life, Van Der Beek says his kids have all processed his illness differently. The actor and his wife Kimberly Brook share six children, whose ages span 3 to 14. When it comes to parenting with an illness, Van Der Beek has made honesty his policy. Being transparent, he says, has "really allowed for some lovely moments of connection" with his kids. James Van Der Beek, Jenna Fischer and the rise of young people getting cancer "We made the choice to just be as honest as we can with them," he says. "They all handle it differently. They all hide it differently. Their concern manifests differently in each of them. But again, telling them what I'm going through, it actually allows them to show up for me in a way that's just been so beautiful. 'Dad, can I get you tea?' 'No, dad, I'll get that for you.' 'How are you feeling today?' They know when I'm having a bad day. I mean, kids, they pick up on everything." Though he's grateful for the new perspective cancer's given him, he obviously wishes we lived in a world where no one had to go through it. That's why he's "shouting from the rooftops: Get screened. Talk to your doctor." "I'm feeling good," he says. "I've learned a lot. But, if I could save people from having to go through this journey, I definitely will. I would still give colorectal cancer zero stars."
