
I refused Ozempic due to horror side effects – could Kourtney Kardashian's £2 ‘natural' alternative help me lose weight?
FROM celebrities to mums at school, it seems everyone is using weight loss jabs these days.
As a woman who has desperately tried everything to slim down, I was tempted to turn to 'wonder' drugs like Ozempic, too.
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I tipped the scales at 17st 7lbs last year, the heaviest I'd ever been.
I felt fat and unfit, having gained 4st since the pandemic due to emotional overeating, as well as taking anxiety medication and hitting my forties.
Despite being a relatively fit person who loves outdoor activities like hiking and skiing, food was my weakness. To compound matters, my job as a self-employed lifestyle journalist meant working unpredictable hours and grabbing fast food on the go.
But the thought of fat jabs terrified me.
I'd read about horrific side effects like vomiting, saggy skin and hair falling out. I wanted something more natural and less daunting – could a so-called 'weight management' capsule created by Kourtney Kardashian's supplements brand be the answer?
Lemme GLP-1 Daily claims to help reduce cravings by supporting the production of GLP-1, a hormone that controls blood sugar and appetite, similar to Semaglutide, the active ingredient in Ozempic.
The supplement contains Eriomin lemon fruit extract, Supresa saffron extract and Morosil blood orange extract.
Critics say the science around whether these three ingredients can really aid weight loss is limited at best.
But small studies have shown Eriomin – an antioxidant – can increase GLP-1 levels, while a two-month study claimed Supresa led to decreased appetite and sugar cravings.
Morosil has a high content of anthocyanins, an antioxidant thought to help the metabolism and boost weight loss.
Doctor slams Kourtney Kardashian's new OZEMPIC pills as star accused of 'cashing in on it' and claims her 'fad product' won't even work
The Lemme supplement was cheaper than jabs, costing £183 for a three-month supply, around £2 per day, plus shipping from America, compared to £199 a month or more for a private supply of Ozempic – and no pharmacist to go through.
However, I sought my doctor's advice before ordering, to ensure it wouldn't negatively interact with any of my medications.
I had other reservations, too.
My mum died of pancreatic cancer in 2007 and I'd read GLP-1 might increase the risk of pancreatitis, as well as the product not undergoing rigorous medical trials, like the jabs have.
Nevertheless, I decided to order a three-month supply online – the minimum time recommended to see an effect – and when they arrived a few days later at the end of January, I was eager to start.
The makers recommend following a healthy diet rich in colourful fruit and veg and fibre, as well as reducing stress, being active and getting restful sleep.
My weight was 17st 7lbs and I was wearing a size 20, with a BMI of 39.6, which is classed as obese for my 5ft 7ins height.
But my first challenge was two back-to-back trips abroad for work, which would involve staying in places with lots of rich food on offer.
Could Lemme help me resist?
I decided to have my dose of two capsules a day first thing. Luckily, they were easy to swallow and tasteless.
Resist cravings
They took a couple of days to take effect, but halfway through a meal I suddenly realised I felt surprisingly full.
Another thing that worked in my favour was coming down with flu after my first trip away. I spent four days in bed, eating very little.
I experienced stomach cramps, though I couldn't tell if they were due to the pills or the illness. Lemme say there are no known side effects, but there may be an adjustment period.
Two weeks into my trial, I was away again, but the capsules seemed to have properly kicked in and I felt less hungry, particularly at breakfast.
I was also trying to stick to two meals a day and make healthy food choices, conscious I was eating less and needing more nutrients.
By the time I got back, I was already 4lbs down on my starting weight and felt delighted.
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On the couple of days where I forgot to take them due to being busy, I noticed I was hungrier, suggesting this wasn't a placebo effect.
Unfortunately, once home, I slipped into bad old habits, especially during the school holidays.
On days out with my eight-year-old daughter Amelia, many attractions only had fast food options like burgers and chips, plus I didn't have time to get to my usual twice-weekly Beatz workout classes.
While I still felt less peckish, my weight loss slowed down due to my food choices, showing that what you eat is as important as how much.
Taking the supplement first thing meant I immediately felt full, plus I was getting a few stomach aches and a bit of constipation. So I decided to experiment with taking them at night instead.
This really helped and my 3am fridge raids for snacks decreased – a habit that had been triggered since starting anxiety medication.
Going into my second month, I noticed I was generally less hungry and losing a pound or two a week.
By the halfway point, I'd dropped 8lb.
In situations where I knew I was going to have to eat, like nights out with friends and dinners with my fiancé John, I was able to choose smaller portions and still feel satisfied.
Decline in cravings
But as I hit the third month, I went into a stressful work period and the juggle of career, home and family meant my food choices were less healthy.
The number on the scales began to creep back up.
Seeing my good work undone, I felt I had let myself down.
I made a huge effort to get back on track, exercising five times a week, with gym sessions on top of my classes, and eating well again.
There was a decline in cravings for sugary snacks and my weight started to go in the right direction.
That was until Easter hit and the temptation of chocolate eggs was too much.
The result was a 4lb gain.
With two weeks of my three-month trial to go, I got back on the wagon with determination.
By the time I'd swallowed the final capsule in my supply, I was 16st 5lbs, more than a stone lighter than when I'd started.
I was comfortably fitting into size 18 clothes and even some size 16.
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My BMI still had a way to go to reach a healthy 24.9, but it was a start.
I was dubious about whether this supplement could work as the science seemed limited, compared to the clear scientific benefits of weight loss jabs.
But I've been pleasantly surprised by Lemme GLP-1.
The results speak for themselves – I'm lighter, my clothes fit better and I've got more energy.
No, it wasn't a dramatic weight loss, but I'm glad, as this feels much more natural.
After all, what is life without enjoyment? With this supplement, you can still have nice food, but the feeling of fullness means you just don't eat as much.
The results speak for themselves – I'm lighter, my clothes fit better and I've got more energy.
I do worry that if I stop taking them, my appetite will return to before.
But ultimately, I believe this is better in the long run as it also teaches you sustainable healthy habits rather than being a dramatic quick fix.
Now I'm ordering more capsules, hoping to lose another 3st to get back to my pre-Covid weight.
I'm determined to get there so I can start planning my wedding to John.
I didn't feel confident enough to walk down the aisle before, but thanks to Lemme, I'm on my way – and won't turn back.

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Scottish Sun
9 hours ago
- Scottish Sun
I was terrified when I got pregnant with ‘Ozempic baby' after weeks on fat jabs – I feared ‘thalidmide effects' or worse
Erica is not alone, pregnant women have flooded social media with their fears, and experts say there is not enough evidence to say the jabs are safe for pregnant women. GRIPPED BY FEAR I was terrified when I got pregnant with 'Ozempic baby' after weeks on fat jabs – I feared 'thalidmide effects' or worse STARING at yet another pregnancy test, Erica Coronado was thrilled but terrified. The 36-year-old had given up hope of a baby after two years of trying and the agony of a stillbirth. 8 Erica Coronado got the news she was pregnant after starting fat jabs in 2023 Credit: Supplied 8 She had started using Ozempic when polycystic ovary syndrome - which can also affect fertilty - saw her gain weight Credit: Supplied 8 Erica, pictured with her husband, Joseph Leyton, 26, had been pregnant in 2020 but gave birth to a stillborn Credit: Supplied So seeing two lines appear on the tests 'felt like a dream' for her and husband Joseph Leyton, 26. Yet they were then gripped by fear — as a month earlier Erica had started taking 'fat jab' Ozempic. Erica, now 37, tells The Sun: 'I was worried my baby might have a defect, or worse.' Desperate for reassurance, Erica turned to TikTok and a Facebook group of other mums who had given birth to 'Ozempic babies'. One new mum posted: 'I lost so much sleep thinking something will go wrong.' Others feared the jabs could be the next thalidomide — a drug given for morning sickness in the late Fifties and early Sixties, that caused severe birth defects. Erica already had children Alexa, 14, and Jordon, 19, from a previous relationship but she and husband Joseph were desperate for a baby of their own. But in 2019, aged 30, she had been diagnosed with polycystic ovary syndrome (PCOS), a common hormone disorder making it harder to conceive. Agonising stillbirth She did get pregnant in 2020 but developed pre-eclampsia and was forced to give birth to her stillborn baby. 'It left such a huge hole in my heart that I thought would never be filled,' she says. Weight Loss Jabs - Pros vs Cons 'I really started to believe it might never happen again.' Fearing she may never conceive, Erica focused on something she felt she could control — her weight. Shortly before her PCOS diagnosis, a symptom of which is weight gain, she had piled on the pounds and reached 16st 4lb. So, in 2023, fed up with diet fails, she started on Ozempic, which mimics the gut hormone GLP-1 that is released after eating and works to slow food's movement through the gut so you feel full for longer. Ozempic is approved in the UK only for type 2 diabetes but in the US off-label for weight loss. In the UK, its equivalent Wegovy is licensed for weight loss, as is Mounjaro. In just two months, Erica lost 15lb but also noticed she had missed two periods — and a pregnancy test proved positive. 'Little miracle' Despite her fears, Erica counts herself lucky as she welcomed her perfectly healthy baby girl, Mariana Jo last year — and hails her 'my little miracle'. 'It's so wonderful to have a baby in the house again,' she gushes. 'Mariana Jo laughs at everything and has developed a fondness for animals. While she will never replace the baby we lost, she brings so much joy to all of us.' But Erica was right to worry — we do not know the effects the 'miracle' weight-loss injections might have on unborn babies. More research is needed into how GLP-1 injections like semaglutide — the drug in Wegovy and Ozempic — and tirzepatide, in Mounjaro, affect pregnancy. 8 Erica welcomed her perfectly healthy baby girl, Mariana Jo last year Credit: Supplied 8 Erica with her husband Joseph and their daughter Credit: Supplied 8 The mum started Ozempic after being fed up with diet fails Credit: AP And health chiefs warned last week the drugs must NOT be taken during pregnancy, so women using them should also use contraception. The Medicines and Healthcare Products Regulatory Agency says: 'Taking the medicine could cause harm to the baby.' Data from animal studies suggests potential for harm, with low birth weight and skeletal abnormalities Professor Rebecca Reynolds Professor Rebecca Reynolds at the University of Edinburgh adds: 'There is hardly any data from human studies to advise if these drugs are safe in pregnancy. 'Data from animal studies suggests potential for harm, with low birth weight and skeletal abnormalities.' Dr Bassel Wattar, a consultant gynaecologist at Anglia Ruskin University says it is rare for pregnant women to join trials like this, as it can be 'riskier and more expensive'. Warning to use effective contraception on injections THE UK's medicines regulator has warned women using weight-loss jabs they must use effective contraception. Medicines and Healthcare products Regulatory Agency (MHRA) has received more than 40 reports of pregnancy among women on weight-loss jabs. Of those, 26 were related to Mounjaro (tirzepatide) and eight to Wegovy/Ozempic (semaglutide). It recommends women taking tirzepatide, in particular, use a non-oral contraceptive because the drug may reduce its effectiveness. The MHRA said: 'This can be a barrier form of contraception (e.g. condom) alongside your pill, or switching to a non-oral contraceptive like the coil or implant.' The MHRA added GLP-1 medicines should not be taken during pregnancy or just before trying to get pregnant. It says to stop taking semaglutide for at least two months before trying to become pregnant, and tirzapatide for at least one month. But studies of rats found semaglutide caused early pregnancy loss and birth defects. Similar was seen in rabbits and monkeys. However, The Sun's resident GP, Dr Zoe Williams, says: 'It's not really plausible that these drugs could be the 'next thalidomide', due to the pharmacology. 'The GLP-1 [weight-loss] drugs are peptides that work by mimicking natural, existing, small proteins in our bodies. In contrast, thalidomide is a drug that can affect blood vessel growth. 'The reason for this new advice is that we don't have enough safety data to know if the medicines could cause harm to the baby. "But it is not likely they would cause such significant birth defects as seen with thalidomide. 'The fact that so far no evidence of danger to the baby has been seen, despite many women getting pregnant on them, is tentatively reassuring.' In fact, the medicines seem to make women MORE fertile and, in the right hands, could prove the most effective treatment for infertility we have seen in decades, experts have told The Sun. 'Happy side effect' Dr Nerys Astbury, Associate Professor of Diet and Obesity at the University of Oxford, tells us: 'It could be that these medicines improve conception chances, we don't know yet.' Dr Wattar says: 'It's not the medication itself but the weight-loss that helps regulate a woman's hormones, allowing her ovaries to function properly again. Pregnancy is more of a happy side effect.' He now prescribes fat jabs to women with PCOS, adding: 'We have found in our clinic these injections are the superior method to help women reach a healthy weight quickly, improving their chances of pregnancy.' But in line with MHRA guidance, he takes his patients OFF the drugs up to two months before couples try to get pregnant. Dr Astbury agrees with Dr Wattar and says: 'The weight loss triggered by obesity medicines is likely to be driving these pregnancies, rather than the drugs. "Losing even a small amount of weight can be enough to reverse infertility.' There should be clearer warnings so women don't accidentally fall pregnant Erica Meanwhile Erica, from California, credits her jabs with helping her conceive, and is calling for greater awareness of their fertility-boosting effects. She was prescribed Ozempic by her doctor, but never told it could affect her chance of having a baby. 'There should be clearer warnings so women don't accidentally fall pregnant,' she warns. The drugs' makers, Eli Lilly (Mounjaro) and Novo Nordisk (Wegovy and Ozempic) advise women who are pregnant, or trying, to not use the medication — and Dr Astbury says: 'Medics prescribing these medications should be advising women to use effective forms of contraception." MHRA also warns Mounjaro may reduce the effectiveness of oral contraceptives in people with obesity, and recommends non-oral forms of contraception such as the implant, coil or condoms. It also says that weight-loss jabs must not be used by mums who are breastfeeding. It also says weight-loss jabs must not be used by mums who are breastfeeding. Dr Alison Cave, MHRA chief safety officer, says: 'Skinny jabs are licensed to treat specific medical conditions and should not be used as aesthetic or cosmetic treatments.' A Novo Nordisk spokesman told us: 'There is limited data with semaglutide use in pregnant women to inform risk for adverse outcomes. Semaglutide should be discontinued in women at least two months before a planned pregnancy, and not used in pregnancy.' A spokesman for Mounjaro maker Eli Lily said: 'This should not be used in pregnancy, and it is recommended to use contraception while using this.' 8 Erica, 37, reveals: "I was worried my baby might have a defect, or worse" Credit: Supplied 8 "While she will never replace the baby we lost, she brings so much joy to all of us," says Erica Credit: Supplied


The Sun
9 hours ago
- The Sun
I was terrified when I got pregnant with ‘Ozempic baby' after weeks on fat jabs – I feared ‘thalidmide effects' or worse
STARING at yet another pregnancy test, Erica Coronado was thrilled but terrified. The 36-year-old had given up hope of a baby after two years of trying and the agony of a stillbirth. 8 8 8 So seeing two lines appear on the tests 'felt like a dream' for her and husband Joseph Leyton, 26. Yet they were then gripped by fear — as a month earlier Erica had started taking ' fat jab ' Ozempic. Erica, now 37, tells The Sun: 'I was worried my baby might have a defect, or worse.' Desperate for reassurance, Erica turned to TikTok and a Facebook group of other mums who had given birth to ' Ozempic babies '. One new mum posted: 'I lost so much sleep thinking something will go wrong.' Others feared the jabs could be the next thalidomide — a drug given for morning sickness in the late Fifties and early Sixties, that caused severe birth defects. Erica already had children Alexa, 14, and Jordon, 19, from a previous relationship but she and husband Joseph were desperate for a baby of their own. But in 2019, aged 30, she had been diagnosed with polycystic ovary syndrome (PCOS), a common hormone disorder making it harder to conceive. Agonising stillbirth She did get pregnant in 2020 but developed pre-eclampsia and was forced to give birth to her stillborn baby. 'It left such a huge hole in my heart that I thought would never be filled,' she says. Weight Loss Jabs - Pros vs Cons 'I really started to believe it might never happen again.' Fearing she may never conceive, Erica focused on something she felt she could control — her weight. Shortly before her PCOS diagnosis, a symptom of which is weight gain, she had piled on the pounds and reached 16st 4lb. So, in 2023, fed up with diet fails, she started on Ozempic, which mimics the gut hormone GLP-1 that is released after eating and works to slow food's movement through the gut so you feel full for longer. Ozempic is approved in the UK only for type 2 diabetes but in the US off-label for weight loss. In the UK, its equivalent Wegovy is licensed for weight loss, as is Mounjaro. In just two months, Erica lost 15lb but also noticed she had missed two periods — and a pregnancy test proved positive. 'Little miracle' Despite her fears, Erica counts herself lucky as she welcomed her perfectly healthy baby girl, Mariana Jo last year — and hails her 'my little miracle'. 'It's so wonderful to have a baby in the house again,' she gushes. 'Mariana Jo laughs at everything and has developed a fondness for animals. While she will never replace the baby we lost, she brings so much joy to all of us.' But Erica was right to worry — we do not know the effects the 'miracle' weight-loss injections might have on unborn babies. More research is needed into how GLP-1 injections like semaglutide — the drug in Wegovy and Ozempic — and tirzepatide, in Mounjaro, affect pregnancy. 8 8 And health chiefs warned last week the drugs must NOT be taken during pregnancy, so women using them should also use contraception. The Medicines and Healthcare Products Regulatory Agency says: 'Taking the medicine could cause harm to the baby.' Professor Rebecca Reynolds at the University of Edinburgh adds: 'There is hardly any data from human studies to advise if these drugs are safe in pregnancy. 'Data from animal studies suggests potential for harm, with low birth weight and skeletal abnormalities.' Dr Bassel Wattar, a consultant gynaecologist at Anglia Ruskin University says it is rare for pregnant women to join trials like this, as it can be 'riskier and more expensive'. Warning to use effective contraception on injections THE UK's medicines regulator has warned women using weight-loss jabs they must use effective contraception. Medicines and Healthcare products Regulatory Agency (MHRA) has received more than 40 reports of pregnancy among women on weight-loss jabs. Of those, 26 were related to Mounjaro (tirzepatide) and eight to Wegovy/Ozempic (semaglutide). It recommends women taking tirzepatide, in particular, use a non-oral contraceptive because the drug may reduce its effectiveness. The MHRA said: 'This can be a barrier form of contraception (e.g. condom) alongside your pill, or switching to a non-oral contraceptive like the coil or implant.' The MHRA added GLP-1 medicines should not be taken during pregnancy or just before trying to get pregnant. It says to stop taking semaglutide for at least two months before trying to become pregnant, and tirzapatide for at least one month. But studies of rats found semaglutide caused early pregnancy loss and birth defects. Similar was seen in rabbits and monkeys. However, The Sun's resident GP, Dr Zoe Williams, says: 'It's not really plausible that these drugs could be the 'next thalidomide', due to the pharmacology. 'The GLP-1 [weight-loss] drugs are peptides that work by mimicking natural, existing, small proteins in our bodies. In contrast, thalidomide is a drug that can affect blood vessel growth. 'The reason for this new advice is that we don't have enough safety data to know if the medicines could cause harm to the baby. "But it is not likely they would cause such significant birth defects as seen with thalidomide. 'The fact that so far no evidence of danger to the baby has been seen, despite many women getting pregnant on them, is tentatively reassuring.' In fact, the medicines seem to make women MORE fertile and, in the right hands, could prove the most effective treatment for infertility we have seen in decades, experts have told The Sun. 'Happy side effect' Dr Nerys Astbury, Associate Professor of Diet and Obesity at the University of Oxford, tells us: 'It could be that these medicines improve conception chances, we don't know yet.' Dr Wattar says: 'It's not the medication itself but the weight-loss that helps regulate a woman's hormones, allowing her ovaries to function properly again. Pregnancy is more of a happy side effect.' He now prescribes fat jabs to women with PCOS, adding: 'We have found in our clinic these injections are the superior method to help women reach a healthy weight quickly, improving their chances of pregnancy.' But in line with MHRA guidance, he takes his patients OFF the drugs up to two months before couples try to get pregnant. Dr Astbury agrees with Dr Wattar and says: 'The weight loss triggered by obesity medicines is likely to be driving these pregnancies, rather than the drugs. "Losing even a small amount of weight can be enough to reverse infertility.' Meanwhile Erica, from California, credits her jabs with helping her conceive, and is calling for greater awareness of their fertility-boosting effects. She was prescribed Ozempic by her doctor, but never told it could affect her chance of having a baby. 'There should be clearer warnings so women don't accidentally fall pregnant,' she warns. The drugs' makers, Eli Lilly (Mounjaro) and Novo Nordisk (Wegovy and Ozempic) advise women who are pregnant, or trying, to not use the medication — and Dr Astbury says: 'Medics prescribing these medications should be advising women to use effective forms of contraception." MHRA also warns Mounjaro may reduce the effectiveness of oral contraceptives in people with obesity, and recommends non-oral forms of contraception such as the implant, coil or condoms. It also says that weight-loss jabs must not be used by mums who are breastfeeding. It also says weight-loss jabs must not be used by mums who are breastfeeding. Dr Alison Cave, MHRA chief safety officer, says: 'Skinny jabs are licensed to treat specific medical conditions and should not be used as aesthetic or cosmetic treatments.' A Novo Nordisk spokesman told us: 'There is limited data with semaglutide use in pregnant women to inform risk for adverse outcomes. Semaglutide should be discontinued in women at least two months before a planned pregnancy, and not used in pregnancy.' A spokesman for Mounjaro maker Eli Lily said: 'This should not be used in pregnancy, and it is recommended to use contraception while using this.' 8 8 Everything you need to know about fat jabs Weight loss jabs are all the rage as studies and patient stories reveal they help people shed flab at almost unbelievable rates, as well as appearing to reduce the risk of serious diseases. Wegovy – a modified version of type 2 diabetes drug Ozempic – and Mounjaro are the leading weight loss injections used in the UK. Wegovy, real name semaglutide, has been used on the NHS for years while Mounjaro (tirzepatide) is a newer and more powerful addition to the market. Mounjaro accounts for most private prescriptions for weight loss and is set to join Wegovy as an NHS staple this year. How do they work? The jabs work by suppressing your appetite, making you eat less so your body burns fat for energy instead and you lose weight. They do this my mimicking a hormone called GLP-1, which signals to the brain when the stomach is full, so the drugs are officially called GLP-1 receptor agonists. They slow down digestion and increase insulin production, lowering blood sugar, which is why they were first developed to treat type 2 diabetes in which patients' sugar levels are too high. Can I get them? NHS prescriptions of weight loss drugs, mainly Wegovy and an older version called Saxenda (chemical name liraglutide), are controlled through specialist weight loss clinics. Typically a patient will have to have a body mass index (BMI) of 30 or higher, classifying them as medically obese, and also have a weight-related health condition such as high blood pressure. GPs generally do not prescribe the drugs for weight loss. Private prescribers offer the jabs, most commonly Mounjaro, to anyone who is obese (BMI of 30+) or overweight (BMI 25-30) with a weight-related health risk. Private pharmacies have been rapped for handing them out too easily and video calls or face-to-face appointments are now mandatory to check a patient is being truthful about their size and health. Are there any risks? Yes – side effects are common but most are relatively mild. Around half of people taking the drug experience gut issues, including sickness, bloating, acid reflux, constipation and diarrhoea. Dr Sarah Jarvis, GP and clinical consultant at said: 'One of the more uncommon side effects is severe acute pancreatitis, which is extremely painful and happens to one in 500 people.' Other uncommon side effects include altered taste, kidney problems, allergic reactions, gallbladder problems and hypoglycemia. Evidence has so far been inconclusive about whether the injections are damaging to patients' mental health. Figures obtained by The Sun show that, up to January 2025, 85 patient deaths in the UK were suspected to be linked to the medicines.


Scottish Sun
9 hours ago
- Scottish Sun
The super ‘common' Ozempic side effect ‘many' will experience – and Sharon Osbourne has admitted she's a victim
FROM eggy burps to stomach-churning nausea, there appears to be an endless list of side effects linked to Ozempic-like jabs. But now, experts are getting candid on a fat jab complication that might shock many. 9 We've all heard about the possible brutal side effects of fat jabs - but now it's time to learn about something most will find surprising Credit: Getty 9 Celebs like Gemma Collins and Rebel Wilson have proudly confessed to using skinny jabs to shed the pounds Credit: instagram 9 Here, experts have set the record straight on a "common" fat jab complication that Sharon Osbourne is currently experiencing Credit: BackGrid Ozempic, a medication originally developed to treat type 2 diabetes, has now become almost as famous as the rapidly-thinning stars who may - or may not - be using it. It's the poster child for a new wave of weight loss injections, but is said to cause 'Ozempic neck', 'Ozempic feet', 'Ozempic butt' and even 'Ozempic lines'. Just last month, Fabulous revealed the newly discovered and incredibly brutal 'Ozempic aftermath', as experts detailed some of the horrendous side effects that are flooding clinics. But not only should people be concerned about the effects it can have on skin, teeth and energy levels, as it turns out there's something else that fat jabs users need to be aware of. Millions across the world are using GLP-1 medications to slim down, using Ozempic, Mounjaro, Wegovy and Zepbound, to drop up to a fifth of their body weight. The drugs, which have been hailed a 'miracle' by some, work by mimicking GLP-1, a hormone released in the body when we are full. While many celebrities, including Amy Schumer, 43, and Lottie Moss, 26, have lost huge amounts of weight and openly talked about using Ozempic, now, Sharon Osbourne, 72, is said to be the latest victim of a worrying side effect. While many are concerned that those using Ozempic will pile on the pounds immediately after coming off of fat jabs, according to experts, 'many' could experience the total opposite. Not only may people find it 'harder to gain weight' after using Ozempic-like jabs, but they could also 'lead to frailty', muscle and strength loss, particularly for those in their 60s. Speaking exclusively to Fabulous, experts have now set the record straight on why some will struggle to gain weight after using fat jabs including, but not limited to, Ozempic. Inside Hollywood's worrying obsession with fat jabs - and what newly slimline Christina Aguilera really thinks of Ozempic claims Mohamed Imran Lakhi, director and superintendent pharmacist at Prescription Doctor, who has over 20 years of experience, tells us: 'When people stop taking medications like Ozempic it's common to see changes in weight management. 'Ozempic works by slowing digestion and reducing appetite, so when someone stops the treatment, their body may return to previous hunger and digestion patterns. 'This can make it harder to gain weight at first because the body is still adjusting to normal insulin and appetite signals. 'Over time, most people's weight will stabilise, but it can feel like a struggle initially. 9 Mohamed Imran Lakhi claims that it is "harder to gain weight at first" after stopping use of fat jabs Credit: Supplied 'This effect isn't unique to Sharon Osbourne. Many who use these medications experience similar challenges once they stop. 'It's important to manage expectations and work closely with healthcare providers to maintain a healthy weight through diet and lifestyle after stopping the medication.' It comes after just days ago, Sharon Osbourne, 72, sparked concern over her gaunt appearance after being spotted out and about in Los Angeles. The former X Factor judge also revealed that after using Ozempic, she is now unable to gain weight. 'Godzilla' of fat jabs Dr Mitra Dutt, a GP from Lloyds Pharmacy Online Doctor, says: 'Mounjaro works by activating two hormonal receptors (GIP and GLP-1), which enhance insulin production, improve insulin sensitivity and work to decrease food intake.' Saxenda, which contains the active ingredient liraglutide, is another weight loss jab that's been available on the NHS since 2020. While Mounjaro is hailed as the "King Kong" fat jabs, a new weight loss drug dubbed "Godzilla" looks set to displace it. Containing the active ingredient retatrutide, slimmers trying the drug lost up to 29 per cent of their weight in less than a year. By comparison, trial results showed semaglutide, known as Ozempic, could lead to 15 per cent weight loss and tirzepatide, aka Mounjaro, to 23 per cent. Retatrutide acts on three different receptors in the brain, 'turbocharging' calorie burning while dulling hunger pangs. Existing weight-loss jabs only suppress appetite, whereas the new treatment also speeds up metabolism. The new drug is still undergoing clinical trials so it's not yet known if it will be made available on the NHS. The TV personality, who lost 42 pounds with the help of the diabetes drug, previously revealed she "didn't actually want to go this thin". Her frail look raised concern after she stepped out with daughter Aimee, 41, for a shopping trip, just days ago. The TV star's face looked slimmer than ever, with her jawline incredibly pronounced. Not only this, but she also left fans concerned after she shared a clip on social media showing off her shrinking frame whilst wearing a loose fitting sweater and cream trousers. I weigh just over 7st. I need to put on 10lb, but however much I eat, I stay the same weight Sharon Osbourne Concerned fans rushed to the comments, as one wrote: 'Sharon, I love you but you are way too thin.' A second chimed in: 'She looks ill, poor thing,' while someone else advised: 'Please stop losing weight.' Meanwhile, another begged: 'Please go eat a cheeseburger.' 9 Sharon Osbourne, pictured in 2013, before using Ozempic Credit: Getty - Contributor 9 Now, she describes herself as looking 'gaunt' Credit: Rex 9 Fans recently expressed concern for the former X Factor judge Credit: Instagram/sharonosbourne While Sharon was initially pleased with her results after starting the medication back in December 2022, she has recently admitted fears she had taken it too far. Revealing all on Howie Mandel's podcast, Sharon confessed: 'I can't put on weight now, and I don't know what it's done to my metabolism, but I just can't seem to put any on, because I think I went too far.' As well as this, Sharon recently told Daily Mail about her "frustration" with the lingering effects, as she shared: 'Now, I weigh just over 7st. I need to put on 10lb, but however much I eat, I stay the same weight. 'I've had enough. I've given up on all interventions. I couldn't have much more facial surgery - there's not that much skin left to stretch, pull or cut. And I won't have any more fillers or Botox. What are the other side effects of weight loss jabs? Like any medication, weight loss jabs can have side effects. Common side effects of injections such as Ozempic include: Nausea: This is the most commonly reported side effect, especially when first starting the medication. It often decreases over time as your body adjusts. Vomiting: Can occur, often in conjunction with nausea. Diarrhea: Some people experience gastrointestinal upset. Constipation: Some individuals may also experience constipation. Stomach pain or discomfort: Some people may experience abdominal pain or discomfort. Reduced appetite: This is often a desired effect for people using Ozempic for weight loss. Indigestion: Can cause a feeling of bloating or discomfort after eating. Serious side effects can also include: Pancreatitis: In rare cases, Ozempic may increase the risk of inflammation of the pancreas, known as pancreatitis, which can cause severe stomach pain, nausea, and vomiting. Kidney problems: There have been reports of kidney issues, including kidney failure, though this is uncommon. Thyroid tumors: There's a potential increased risk of thyroid cancer, although this risk is based on animal studies. It is not confirmed in humans, but people with a history of thyroid cancer should avoid Ozempic. Vision problems: Rapid changes in blood sugar levels may affect vision, and some people have reported blurry vision when taking Ozempic. Hypoglycemia (low blood sugar): Especially if used with other medications like sulfonylureas or insulin. 'I don't think I'll ever be happy with the way I look. 'I've learned my lesson. This is me. It's finally time to leave well alone.' Not only this, but Sharon claimed doctors are at a loss as to why she hasn't been able to gain weight back after she stopped using Ozempic months ago, as she stressed: 'The doctors can't figure it out.' But Kiran Jones, a clinical pharmacist at Oxford Online Pharmacy, tells us that Ozempic users over 65 will struggle much more than others to gain weight after coming off of fat jabs. It can become quite difficult to eat enough to put weight back on Kiran Jones Kiran says: 'Media personality Sharon Osbourne has been vocal about her use of Ozempic and has lost over 40 pounds with the help of the popular medication. 'However, she's since revealed that she's struggling to regain weight since coming off the drug, as she feels she's lost too much weight. 'While many people do regain weight after stopping Ozempic and other GLP-1s, this isn't always the case for patients over 65. 'Older adults often experience a natural decline in appetite as part of the ageing process. Add the lasting effects of a GLP-1 medicine, and it can become quite difficult to eat enough to put weight back on.' 9 Kiran Jones recognises that Ozempic users over 65 will struggle much more than others to gain weight after coming off of the fat jabs Credit: Supplied As well as this, Kiran adds: 'In some cases, the weight loss itself changes the body's needs. 'With less muscle and a slower metabolism, older patients simply don't need as much food, so if appetite stays low, weight regain can slow or stop. 'What looks like 'success' from a weight loss perspective can actually lead to frailty in this group, especially if they've lost muscle or strength along the way.' Kiran observes a 'shift' that can 'stick', as she continues: 'Many patients adjust their habits while on Ozempic, they start eating smaller meals and feeling full faster. 'That shift can stick, even after stopping the medication. For older people, who may already eat lightly, this can make it even harder to increase food intake again. 'It's worth noting that older adults are more vulnerable to the side effects of nausea or stomach upset, even after stopping. "If food feels unappealing or difficult to digest, eating more becomes a real challenge. 'For patients over 65, weight management after Ozempic needs a more tailored approach. It's not just about weight on the scale. It's about strength, function, and making sure people stay well-nourished. 'This group may benefit from extra clinical support, not just during treatment but also after, especially if they're struggling to gain weight or feel well.' It could potentially have put her in a position where it is extremely hard to regain the weight she has lost, with regards to muscle and bone strength Dr. Ed Robinson Similarly, Dr Ed Robinson, a leading aesthetic doctor, recognises that perimenopausal women, as well as those battling menopause, may struggle to gain weight after using Ozempic. Dr Ed explains: 'The only way in which Ozempic could have long-term effects like this is if you lost so much weight and so much muscular atrophy while taking the drug. 'Then it is very difficult to put weight back on - especially for menopausal or postmenopausal women who don't have the levels of hormone anymore.' Dr Ed describes Sharon as 'so thin' and 'quite frail looking', as he concludes: 'It could potentially have put her in a position where it is extremely hard to regain the weight she has lost, with regards to muscle and bone strength. 'If you are too frail, it is hard to do the necessary exercises to boost strength.' 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