Latest news with #GLP-1
Scottish Sun
2 hours ago
- Health
- Scottish Sun
Ozempic-like fat jabs ‘boost men's sex lives – reversing testosterone drops'
Click to share on X/Twitter (Opens in new window) Click to share on Facebook (Opens in new window) WEIGHT loss jabs could boost men's sex lives, a study suggests. Research found injections like Wegovy and Mounjaro can raise blokes' low testosterone levels. Sign up for Scottish Sun newsletter Sign up 1 More than a million people in the UK use weight loss injections (stock image) Credit: Getty The hormone is a big factor in the male sex drive, known as libido, as well as a driver of strength, muscle gain and fat loss. Testosterone levels commonly decline with age or when someone is obese or has type 2 diabetes – amounting to millions of men in the UK. A study by the St Louis University Hospital in Missouri, USA, tracked 110 men in their 40s, 50s and 60s who were being treated with semaglutide – aka Ozempic or Wegovy – or tirzepatide, known as Mounjaro. At the start of their treatment just 53 per cent of the men had normal testosterone levels. Symptoms of low testosterone can include tiredness, weakness and fat gain, feeling depressed, brain fog, and a lack of desire or inability to perform in the bedroom. Treatment increased rate of healthy testosterone After 18 months of treatment with the fat jabs, the proportion of men with healthy hormone levels increased to 77 per cent. Study author Dr Shellsea Portillo Canales said: 'Our study is among the first to provide compelling evidence that low testosterone can be reversed with the use of commonly prescribed anti-obesity medications. 'Doctors and their patients can now consider this class of medications not only for the treatment of obesity and to control blood sugar, but also to benefit men's reproductive health.' More than 1.5million Brits are thought to be taking weight loss injections, known as GLP-1 receptor agonists. NHS prescriptions have rocketed from 1.4million in 2023 to 2.7million in 2024, and more than a million people are paying for them privately. I went from 27 lbs in six weeks with Mounjaro after 15 years of trying to lose weight it has completely changed my life As well as rapid weight loss and treatment for type 2 diabetes, research suggests the jabs may also reduce the risk of some cancers, heart diseases and dementia.
NBC News
3 hours ago
- Health
- NBC News
Weight loss drugs can boost testosterone in men, study finds
Popular weight loss medications like Ozempic can help reverse low testosterone levels in men with obesity or Type 2 diabetes, according to new research. Building on previous studies that show weight loss surgery or lifestyle changes can increase testosterone levels in the body, researchers at SSM Health St. Louis University Hospital analyzed the electronic health records of 110 men with obesity or Type 2 diabetes to monitor changes in the hormone while taking GLP-1 receptor agonists, such as semgalutide and tirzepatide. They measured testosterone levels before taking the medications and for 18 months after starting the treatment. Roughly half of the men had low to low-normal testosterone at the start of the study and most reached normal levels after treatment. 'The increases we observed were more modest than what you would typically see with testosterone replacement therapy,' said lead author Dr. Shellsea Portillo Canales, endocrinologist at SSM Health St. Louis University Hospital, via email. 'However, they occurred naturally, without testosterone replacement therapy (TRT), and likely reflect the body recovering its normal hormone production as weight and insulin resistance improved.' The study highlights the need for men already on testosterone therapies to closely monitor their levels after starting weight loss medications, Portillo said. In some cases, men may need to have their testosterone supplement doses lowered or discontinued, especially if their testosterone normalizes while on weight loss medications. There are limitations to the new study. The findings don't prove the increase in testosterone levels was caused by the drugs semaglutide or tirzepatide. It was a retrospective study, meaning the researchers analyzed existing medical records over time, rather than conducting a randomized clinical trial. And they didn't check testosterone levels after the men stopped the drugs. 'If weight is regained, testosterone levels could potentially drop again,' Portillo said. The study findings were presented this Monday at ENDO 2025, the Endocrine Society's annual meeting in San Francisco. The researchers are planning to submit it to a medical journal for peer review. Dr. Susan Spratt, professor of medicine at Duke University School of Medicine, said many men are overtreated with testosterone therapy when they have levels on the lower normal side. 'It would be better to treat obesity or diabetes and naturally increase testosterone than to prescribe testosterone — which has known risks,' said Spratt, who was not part of the study. Some risks of testosterone therapy include worsening sleep apnea, acne, enlarging the prostate or breasts, increasing growth of prostate cancer, reducing sperm counts, causing the testicles to shrink and increasing the risk of clots, according to Mayo Clinic. The study shows the dual benefit of weight loss medications in men, said Dr. Fatima Cody Stanford, obesity medicine physician scientist at Massachusetts General Hospital and Harvard Medical School. 'The findings from this study highlight an important intersection between metabolic health and hormonal balance,' Stanford said. 'This dual benefit underscores the potential of these medications to enhance overall health outcomes, including reproductive health, in this population.' Normal testosterone levels are between 300 to 1,000 nanograms per deciliter. Testosterone tends to decline gradually with age, starting around the late 30s to early 40s. By age 75, the average male testosterone level drops to about 65% of the average level seen in young adults, Portillo said. 'Improving testosterone can enhance quality of life and possibly reduce health risks associated with low levels,' Portillo said. Spratt said it's important to distinguish between normal testosterone levels that increase but remain in the normal range, versus low testosterone levels that increase to normal. Testosterone levels that are truly low are most concerning because low testosterone can lower bone density (which increases the risk of fracture), reduce muscle mass, lower hemoglobin (red blood cells) levels and decrease libido, experts say. 'However, treating low normal testosterone without a known cause is controversial and has increased in the past decade likely due to direct-to-consumer marketing,' Spratt said. The researchers only included men in the study, because they didn't expect weight loss drugs to raise testosterone levels in women. 'In general, we don't routinely measure testosterone in women, unless there are signs of a hormonal imbalance, like excess facial hair (hirsutism), irregular periods, infertility or signs of masculinization,' Portillo said. In those cases, testosterone testing can help diagnose conditions like polycystic ovary syndrome, or PCOS, adrenal disorders or rare tumors. Some studies in women with PCOS, a condition which raises testosterone levels, suggest GLP-1 therapies may help slightly lower testosterone by improving metabolism and reducing insulin resistance. Certain conditions are well known to decrease testosterone in men, including excess fat, especially around the abdomen, which interferes with hormone signals from the brain to the testicle, experts say.
New York Post
3 hours ago
- Health
- New York Post
Weight loss drugs like Ozempic can raise low testosterone — what that means for men
Big gland energy! Testosterone fuels male sex drive and erectile function and influences everything from bone density and muscle mass to fat distribution, red blood cell production, mood and energy levels. Unfortunately, testosterone levels naturally decline with age. Older men may feel more tired and grouchy and less interested in sex. Not to mention the hair loss, bone fractures and weight gain around the waist that often accompany low T. Advertisement 3 Testosterone levels significantly affect a man's physical, sexual and mental well-being. AntonioDiaz – Luckily, there are ways to naturally boost testosterone. Exercise, especially strength training, a healthy diet, stress reduction, adequate sleep and weight management, particularly for those who are overweight, are just a few. A new study highlights another tool that may help elevate these levels — Ozempic and other GLP-1 drugs. Advertisement Research indicates that weight loss can enhance testosterone levels because excess body fat contains the enzyme aromatase, which converts testosterone into estrogen. 'While it is well-known that weight loss from lifestyle changes or bariatric surgery increases testosterone levels, the impact that anti-obesity medications may also have on these levels has not been widely studied,' said Dr. Shellsea Portillo Canales, an endocrinology fellow at SSM Health St. Louis University Hospital in Missouri. 'Our study is among the first to provide compelling evidence that low testosterone can be reversed with the use of commonly prescribed anti-obesity medications.' 3 Ozempic and other GLP-1 drugs may help elevate testosterone levels through weight loss. mbruxelle – Advertisement Portillo Canales' team analyzed the records of 110 adult men with obesity or Type 2 diabetes taking the weight-loss medications semaglutide (Wegovy), dulaglutide (Trulicity) or tirzepatide (Zepbound) but not participating in testosterone or hormonal therapy. These three drugs mimic the effects of GLP-1, a natural hormone in the body that regulates blood sugar and appetite, often leading to lower blood sugar and weight loss. On average, the participants experienced 10% weight loss and saw their testosterone levels rise from 53% to 77% over 18 months. Advertisement Weight loss improves insulin sensitivity, reduces inflammation and lowers aromatase activity, which contribute to increased testosterone production. The findings were presented Monday at ENDO 2025, the Endocrine Society's meeting in San Francisco. 'Results from this study show that there is a direct correlation between the use of anti-obesity medications and testosterone levels,' said Portillo Canales. 'Doctors and their patients can now consider this class of medications not only for the treatment of obesity and to control blood sugar, but also to benefit men's reproductive health.' 3 It's important to keep an eye on testosterone levels, which naturally decline with age. Larisa – GLP-1 drugs are not without risks, though. Nausea, vomiting and diarrhea are among the most commonly reported side effects. Inflammation of the pancreas, vision changes, stomach paralysis and even death are rare but serious concerns. Advertisement In the 20 years since the first GLP-1 drug was approved to treat diabetes, researchers have been exploring other uses for these popular meds. Research continues on their potential to slow the progression of Alzheimer's disease, improve sleep apnea, reduce alcohol cravings and treat liver disease, among other conditions.
India Today
4 hours ago
- Health
- India Today
Dark chocolates vs dates: Which is the healthier sweet for your pantry?
The world today is a paradox. We're glued to our devices, yet determined to hit our daily step count. We aim to cut down on junk food and avoid gluten, but saying no to dessert is easier said than done. Even as sedentary lifestyles become the norm, there's a growing wave of health-conscious choices sweeping course, eating clean and healthy is essential, but it also entails a certain dilemma – what to eat and what not to? Reducing sugar intake becomes the first instinct, along with junk food. And when it comes to indulging in sweet treats, the debate often arises between the health benefits of dark chocolate and dark chocolates and dates offer unique nutritional profiles, but which is truly better for your health?Dark Chocolate vs Dates Sugar ContentDark chocolate is considered a heart-healthy food, and experts agree. Now, the quantity of sugar may vary in different varieties, but when the cocoa percentage is higher, the sugar content is generally lower. Therefore, experts recommend dark chocolate, which is at least 70 to 80 per cent dates are nature's candy with a high glycaemic index. 'Dates have natural sugar, which is approximately 68.84g in 100g, and may also trigger further sugar cravings due to their relatively high glycaemic load,' Vani Krishna, chief nutritionist at Manipal Hospital, Varthur tells India Today. Dark chocolate is rich in antioxidants (Photo: Pexels) Antioxidant-richDark chocolate is not just a treat but an antioxidant powerhouse. It has high flavonoid (plant-based antioxidant) content, especially when it contains over 75 per cent cocoa. This results in several heart health benefits, such as improved vascular function, lower blood pressure, and enhanced insulin sensitivity. These effects are attributed to the presence of compounds like epicatechin and catechin, which have been shown to reduce oxidative stress and inflammation, the nutritionist contrast, dates are rich in potassium, magnesium, and vitamin B6 but their cardiovascular benefits are less pronounced due to their high natural sugar and feeling of fullnessDates are a rich source of dietary fibre, with about 3.3 grams per two medium-sized dates, making them excellent for promoting digestion and chocolate, too, can help keep your appetite in check. How? It contains polyphenols that stimulate the release of satiety hormones such as GLP-1 and PYY, which aid in appetite control and reduce cravings. This makes it a viable option for those looking to maintain a balanced diet without overindulging in sugar. Dates are rich in fibre and minerals (Photo: Pexels) MineralsNow this is one area where both these foods add value of their own. Dates are packed with potassium, magnesium, iron, and fibre, supporting bowel movements and gut health. However, for those monitoring sugar intake, dark chocolate is a preferable option, containing substantially less sugar than dates, especially if consumed in its unsweetened dark chocolate also provides significant amounts of iron, magnesium, and copper, it stands out for its antioxidant-rich profile—which, according to nutritionist Vani Krishna, surpasses that of dates. These antioxidants not only help reduce inflammation but also support overall cardiovascular let's not forget the emotional side - chocolate and feelings share a deep connection. A bite of dark chocolate can lift your mood, but that doesn't mean you should biteOverall, the choice between dark chocolate and dates depends on individual dietary needs and health goals. Dark chocolate appears to have an edge in terms of heart health and antioxidant properties, making it a valuable addition to a balanced diet when consumed in moderation. 'I would suggest dark chocolate is healthy as it contains the richest dietary sources of flavanols, including epicatechin and catechin. It is proven to reduce oxidative stress, improve vascular function, and help to lower inflammatory markers,' says dates, with their high fibre and mineral content, are an excellent choice for digestive health but should be eaten with caution due to their high glycaemic moderation is key when it comes to food, one thing is certain – both options can be healthier alternatives to processed sugary snacks if integrated thoughtfully into one's diet.- EndsTrending Reel
The Irish Sun
5 hours ago
- Health
- The Irish Sun
I lost 6 stone on Mounjaro and here's 6 things I wish I'd known before starting – a 5p drink is essential for the nausea
A WOMAN who lost six stone after taking weight loss jab Mounjaro has revealed the six things she wishes she knew before starting and says a 5p drink made all the difference. Lucy Davies, who shares her journey on TikTok under the name 2 Lucy Davies lost 6 stones on Mounjaro Credit: SWNS 2 She shared her dramatic weight loss journey with followers on Tiktok Credit: SWNS Lucy turned to Mounjaro, a jab that's part of a new generation of weight-loss meds, to help her slim down. It's similar to Ozempic, but packs an even bigger punch when it comes to appetite control. The results were no doubt impressive but Lucy insists there's plenty people don't tell you before starting. Now feeling lighter, healthier and more confident, she's spilling the tea, quite literally, on the real-life hacks that helped her through it. Read more on mounjaro Here are Lucy's top tips for new users. Her number one survival tool was a mug of peppermint tea. The herbal brew, which costs just 5p a bag in some shops, became her go-to remedy for the queasy side effects that came with the jab. She swears it was the only thing that settled her stomach when the Most read in Fabulous She also learned the hard way that fizzy drinks are a no-go. Even one can left her feeling I've lost nearly 6 stone in 9 months on fat jabs - trolls call me 'lazy' & say it's the 'easy way out' but I don't care 'It just wasn't worth it,' she says, and warns others to give the bubbles a miss unless they fancy an upset stomach. Hydration, too, played a big part in her transformation. While most users are told to aim for two litres of water a day, Lucy pushed that up to three and says the benefits were obvious. More energy, fewer headaches, and a much easier ride through the jab's side effects. But while Mounjaro helps shrink your appetite, Lucy warns that doesn't mean you can skip meals. One mistake she made early on was not eating enough and it left her wiped out. She recommends tracking your calories, not to diet harder, but to make sure your body's still getting the fuel it needs to function properly. Another crucial tip is not to fall for the idea that this jab is some kind of magic wand. Fellow user Kathryn, who's dropped three stone herself, says "Mounjaro is a tool, not a miracle. You still need to put the work in". That means eating better, moving more, and listening to your body. Not every vitamin under the sun will help, either. It's about finding what works for you and not overloading your system with unnecessary supplements. One thing Kathryn says is often overlooked was fibre. While everyone's banging on about protein, she found getting enough fibre made a huge difference, keeping her digestion in check and helping her feel fuller for longer. A common misconception among jab users is that they This can lead to unnecessary concerns about whether their current dose is working, especially when they're taking lower doses. One of the ways GLP-1 medications like hunger signals in the brain, helping patients feel satisfied with smaller portions. But they do not and should not eliminate hunger altogether. Kiran Jones, clinical pharmacist at even patients on higher doses like 12.5mg or 15mg should feel hunger at times." He added: 'People think these medicines switch off hunger completely, but that's not how they work. "Being able to eat is normal. Success looks different for everyone, and often, the biggest wins are quiet ones: more energy, less breathlessness, and better sleep. 'Becoming healthier without extreme diets or private clinics is a powerful example of what good, regulated care can achieve. "Patients need safety, not pressure.' What to do if you lose too much weight too quickly whilst on Mounjaro IF you're losing too much weight too quickly while on Mounjaro, it's important to take action to avoid potential health risks like muscle loss, malnutrition, dehydration, and fatigue. Here's what you can do: Evaluate Your Caloric Intake Mounjaro reduces appetite, which can make it easy to eat too little. If you're losing weight too fast (more than two to three lbs per week after the initial adjustment period), try: Tracking your food intake to ensure you're eating enough calories (apps like MyFitnessPal can help). Increasing protein intake to preserve muscle mass (aim for 0.6–1g per pound of body weight). Adding healthy fats and complex carbs (e.g., avocados, nuts, whole grains) for balanced energy. Adjust Your Dosage (With Doctor's Approval) If your weight loss is too rapid or causing side effects, your doctor may: Pause dose increases or lower your dosage. Adjust your treatment plan to stabilise your weight loss. Strength Training & Exercise To prevent muscle loss: Incorporate resistance training at least two to three times per week. Stay active with low-impact exercises like walking or yoga. Hydrate & Manage Electrolytes Drink enough water (Mounjaro can reduce thirst). Electrolytes matter - Consider adding magnesium, sodium, and potassium if you feel weak or fatigued. Monitor for Malnutrition & Deficiencies Rapid weight loss can cause vitamin/mineral deficiencies (especially B12, iron, and electrolytes). If you experience: Fatigue, hair loss, or dizziness, ask your doctor about supplements. Consider Further Medical Guidance If your weight loss is excessive or causing health concerns, speak with your healthcare provider. They might adjust your dosage, diet, or exercise plan to help stabilise your weight loss.
