
Switzerland approves first malaria drug for infants
Coartem Baby is a reformulation of the existing Coartem (artemether-lumefantrine) combination therapy. The new formulation was developed through a collaboration between Novartis and the Medicines for Malaria Venture (MMV), with support from the PAMAfrica consortium.
The clinical development program was co-funded by the European & Developing Countries Clinical Trials Partnership and the Swedish International Development Cooperation Agency. The approval was based on positive data from the Phase II/III CALINA study, which demonstrated that Coartem Baby has a pharmacokinetic profile suitable for infants under 5 kilograms and exhibits good efficacy and safety.
Global Health Impact
Malaria remains one of the world's deadliest diseases, particularly among children under five years old in Africa. In 2023, there were an estimated 36 million pregnancies in 33 African countries where malaria is widespread, with about one in three mothers infected with malaria during pregnancy, raising the risk of transmission to their newborns.

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News18
a day ago
- News18
Police bust illegal kidney transplant network in Pakistans Punjab; 8 arrested
Lahore, Jul 29 (PTI) Eight members of an illegal kidney transplant network, including doctors and nurses, have been arrested in Pakistan's Punjab province, an official said on Tuesday. According to a spokesperson of the Punjab Human Organ Transplantation Authority, a network involved in illegal kidney transplants has been uncovered in Sheikhupura, some 50-km from Lahore. He said the illegal kidney transplant procedures were conducted at a private hospital. 'During the raid, a kidney was being removed from a resident of Sheikhupura to be transplanted into an African national," the spokesperson said. Eight people, including doctors and nurses, have been arrested, he added. He said the network would charge at least PKR 7 million from a person for the illegal transplant. Usually, the kidneys are sold for up to PKR 10 million to the recipient, but donors hardly get 10 per cent of the total amount. Raids are being conducted to arrest more people involved in the illegal network, he said. The commercial trade of human organs was made illegal in Pakistan in 2010. The punishment for those caught includes a decade-long jail term and a huge fine. There has been a rise in organ trafficking in Pakistan as people struggle with low wages and poor enforcement of the law. A couple of years ago, the Punjab government had arrested the ring leader of such a network for extracting the kidneys of more than 300 people and transplanting them into rich clients. PTI MZ ZH ZH (This story has not been edited by News18 staff and is published from a syndicated news agency feed - PTI) view comments First Published: July 29, 2025, 19:45 IST Disclaimer: Comments reflect users' views, not News18's. Please keep discussions respectful and constructive. Abusive, defamatory, or illegal comments will be removed. News18 may disable any comment at its discretion. By posting, you agree to our Terms of Use and Privacy Policy.


Hindustan Times
2 days ago
- Hindustan Times
Bladder cancer explained: Symptoms, causes, and recovery as Deion Sanders reveals diagnosis
NFL Hall of Famer and Colorado football coach Deion Sanders has gone public with a major health update: he was recently diagnosed with bladder cancer and has undergone a complete bladder removal surgery. Though now cancer-free, Sanders has urged others to prioritise their health. During a press conference held on Monday, he revealed that he had known about his condition during the NFL draft weekend but kept it private, even from his family, saying it was an issue with his foot. Deion Sanders updated the public on his illness, revealing an aggressive bladder cancer diagnosis.(Getty Images via AFP) Since 2021, he has undergone 14 surgeries, with the latest one being among the most difficult, per ESPN. Sanders said he was cancer-free after the surgery, but still faces post-operative challenges like urinary incontinence. He said many deal with it, but few talk about it. 'Let's stop being ashamed of it, and let's deal with it head-on,' he said during the press conference. Also read: Will Deion Sanders step away from Colorado Buffaloes after cancer battle? Doctors say 'We'll keep him on…' What is bladder cancer, and common symptoms? Bladder cancer is a rather rare but serious disease that develops in the lining of the bladder, the organ that stores urine. If diagnosed early, sometimes it is possible to cure this type of cancer; however, about 75 per cent of early-stage cases eventually recur, and therefore constant watch is needed. Signs of bladder cancer include hematuria, a burning sensation when passing urine, frequent urination, difficulty in urination or a weak urine stream, and persistent bladder infections. Early symptoms are frequently mistaken for something less threatening, which can delay diagnosis, especially in women, the Cleveland Clinic report said. Who is more prone to contracting bladder cancer? Bladder cancer is listed as the fourth most common cancer in males, particularly affecting men aged 55 years and above. The Cleveland Clinic report further said that white men are twice as likely to be diagnosed with bladder cancer when compared to men of African descent. Some key reasons that might cause bladder cancer include: smoking, prolonged bladder infections, chronic use of catheters, exposure to industrial chemicals such as dyes, rubber, textiles, etc. Diagnosis and treatment options Physicians usually resort to tests such as urinalysis, cytology, and cystoscopy to diagnose a person. If the diagnosis is positive for cancer, then it gets staged by other imaging investigations such as MRI, CT, and even bone scans. Treatment options for bladder cancer include chemotherapy, radiation therapy, immunotherapy such as BCG or PD L-1 inhibitors, or targeted therapy, depending on genetic mutations. Treatment can also include surgery, depending on severity, including TURBT for early cases or radical cystectomy for invasive cancers. Prognosis and outlook for bladder cancer Bladder cancer can be fatal if untreated because it metastasizes into different parts of the body. Early diagnosis and treatment greatly increase the survival rate, with a 96% five-year survival rate after diagnosis in early stages. For those who have been diagnosed, it is self-care that becomes top priority; regular checkups, eating a heart-healthy and high-fibre diet, engaging in bodily exercises, and reaching out to supportive networks. For a select population, it might also mean going through surgery with urinary diversion and then adjusting to a different way of managing urine, according to another report from Cancer Research. FAQs Q: Is bladder cancer fatal? A: If left untreated, bladder cancer can spread and become life-threatening. Early treatment greatly improves survival rates. Q: What was Deion Sanders' treatment for bladder cancer? A: Sanders underwent complete bladder removal surgery and is now cancer-free. Q: What causes bladder cancer? A: Risk factors include smoking, exposure to industrial chemicals, chronic bladder infections, and certain cancer treatments. Q: What is the first symptom of bladder cancer? A: Blood in the urine (hematuria), either visible or microscopic, is usually the first sign. Q: Is Deion Sanders still coaching? A: Yes. Despite his health challenges, Sanders remains active and is continuing his coaching career at the University of Colorado.


The Print
2 days ago
- The Print
Merck Foundation Together with African and Asian First Ladies Mark ‘World Assisted Reproductive Technology Day' 2025
Banjul [The Gambia] / Mumbai (Maharashtra) [India], July 28: Merck Foundation, the philanthropic arm of Merck KGaA Germany, marks 'World ART (Assisted Reproductive Technology) Day 2025' together with African and Asian First Ladies, who are also the Ambassadors of 'Merck Foundation More Than a Mother' Campaign, by building and advancing fertility care capacity in Africa and Asia. Senator, Dr. Rasha Kelej, CEO of Merck Foundation and President of 'More Than a Mother' emphasized, 'At Merck Foundation we mark World Assisted Reproductive Technology Day by building Fertility and Reproductive Care capacity and empowering infertile women by improving their access to information, change of mindset and quality & equitable fertility care across Africa & Asia as part of our 'More than a Mother' campaign. I am very proud to share that we have provided till today 716 scholarships of Embryology, Fertility and Sexual & Reproductive care to young doctors from 41 countries in Africa and Asia to be the local Embryologists, Fertility & Reproductive care experts in their countries. Moreover, many of our Alumni were trained to be the first local experts in their countries where they never had even a single local embryologist or fertility specialist before our program such as; The Gambia, Burundi, Guinea, Chad, Niger, Sierra Leone, Liberia, Malawi, Congo, Mozambique and more. Together with African First Ladies, and other important partners, we are making history and reshaping the landscape of fertility & Reproductive care across Africa and beyond,' added Dr. Kelej. Merck Foundation 'More Than a Mother' is a powerful campaign that defines interventions to build quality and equitable Reproductive and Fertility Care Capacity, Break Infertility Stigma and Raise Awareness about Infertility Prevention and Male Infertility. Merck Foundation has provided 2280 scholarships for doctors from 52 countries in 44 critical and underserved medical specialties. 'To give an overview, out of our total 716 scholarships for Fertility and Reproductive care, we have provided more than 324 Scholarships for clinical and practical training to Fertility Specialists and Embryologists, and more than 392 Scholarships for PG Diploma and Master Degree in Sexual and Reproductive Medicine, Clinical Psychiatry, Women's Health, Biotechnology of Human Assisted Reproduction & Embryology, Urology, Laparoscopic Surgical skills and Family Medicine to doctors from 41 countries across Africa and Asia. We are proud of this achievement,' added Dr. Rasha Kelej. According to WHO data, more than 180 million couples in developing countries – that is 1 in every 4 couple, suffer from infertility. In many cultures in Africa, infertility is a huge stigma. Women are solely blamed for failing to conceive and the social stigma of childlessness, especially for women leads to isolation and stigmatization and results in discrimination and ostracism. This mostly also leads to divorce or physical or psychological violence. As a part of 'More Than a Mother' Campaign, Merck Foundation has launched many initiatives to break this stigma and create a culture shift. Merck Foundation has also been empowering childless and infertile women through their 'Empowering Berna' initiative under their 'More Than a Mother' movement. This initiative helps women who cannot be treated for infertility anymore by helping them get trained to establish small businesses so that they can be independent and rebuild their lives. Through 'Empowering Berna', the lives of many infertile women have been transformed in many African countries like Kenya, Uganda, Nigeria, Central African Republic, Niger, Malawi, and many more. 'It's all about giving every woman the respect and the help she deserves to lead a fulfilling life, with or without a child,' added Dr. Kelej. Moreover, Merck Foundation has trained more than 3700 media representatives from more than 35 countries to raise community awareness and break the stigma around infertility and infertile and childless women. Merck Foundation in partnership with Africa's First Ladies, has also launched 'More Than Mother' Children's storybook to emphasize strong family values of love and respect from a young age which will reflect on eliminating the stigma of infertility and the resulted domestic violence in the future. The storybooks have been localized for each country and in three languages, English, French and Portuguese to better connect with the young readers. The book has also been adapted to an animation film. Watch More Than a Mother Animation Film here: Merck Foundation's pan African TV program 'Our Africa', that is conceptualized, produced, directed, and co-hosted by Senator, Dr. Rasha Kelej, CEO of Merck Foundation and features African Fashion Designers, Singers, and prominent experts from various domains with the aim to raise awareness and create a culture shift across Africa, has many episodes dedicated to raise awareness about infertility and breaking infertility stigma. Watch the episodes here: Episode 3: Episode 5: Episode 10: Merck Foundation has also released about 30 songs, many of these songs have been created with the aim to break the infertility stigma, as a part of their 'More Than a Mother' campaign. Listen to some of the songs here: 1. Watch, share & subscribe to the 'Plus qu'une MERE' composed and sung by Ms. Lucky-Lou, the daughter of The President and The First Lady of Burundi: 2. Watch, share & subscribe to the 'More Than a Mother' song by Cwesi Oteng and Adina from Ghana: 3. Watch, share & subscribe to the 'More Than a Mother' song by Zambian Soul Singer Wezi: 4. Watch, share & subscribe to the 'More Than a Mother' song by Sunita Daffeh from the Gambia: Listen to all 'More than a Mother' songs here: 'To address this important issue of breaking infertility stigma and also a wide range of other social issues, we annually launch Merck Foundation 'More Than a Mother' Awards in partnership with African First Ladies. I would also like to invite the African Community of Media, Fashion, Filmmaking, and Musicians, students, and potential talents in these fields to apply for the awards this year by sharing their creative work on submit@ concluded Senator, Dr. Rasha Kelej. Click on the link below to Download Merck Foundation App Join the conversation on our social media platforms below and let your voice be heard! Facebook: Merck Foundation X: @MerckFoundation YouTube: MerckFoundation Instagram: Merck Foundation Threads: Merck Foundation Flickr: Merck Foundation Website: (ADVERTORIAL DISCLAIMER: The above press release has been provided by BusinessWire India. ANI will not be responsible in any way for the content of the same) This story is auto-generated from a syndicated feed. ThePrint holds no responsibility for its content.