logo
Mirum Pharmaceuticals Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

Mirum Pharmaceuticals Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

Yahooa day ago

FOSTER CITY, Calif., June 11, 2025--(BUSINESS WIRE)--Mirum Pharmaceuticals, Inc. (Nasdaq: MIRM) today announced that on June 10, 2025, the Compensation Committee of Mirum's Board of Directors granted inducement awards consisting of non-qualified stock options to purchase 115,620 shares of common stock and 57,740 restricted stock units ("RSUs") to 10 new employees under Mirum's 2020 Inducement Plan. The Compensation Committee of Mirum's Board of Directors approved the awards as an inducement material to the new employees' employment in accordance with Nasdaq Listing Rule 5635(c)(4).
Each stock option has an exercise price per share equal to $48.98 per share, Mirum's closing trading price on June 10, 2025, and will vest over four years, with 25% of the underlying shares vesting on the one-year anniversary of the applicable vesting commencement date and the balance of the underlying shares vesting monthly thereafter over 36 months, subject to the new employees' continued service relationship with Mirum through the applicable vesting dates. The RSUs will vest over three years, with 33% of the underlying shares vesting on each anniversary of the applicable vesting commencement date, subject to the new employees' continued service relationship with Mirum through the applicable vesting dates. The awards are subject to the terms and conditions of Mirum's 2020 Inducement Plan and the terms and conditions of an applicable award agreement covering the grant.
About Mirum Pharmaceuticals, Inc.
Mirum Pharmaceuticals, Inc. is a biopharmaceutical company dedicated to transforming the treatment of rare diseases affecting children and adults. Mirum has three approved medications: LIVMARLI® (maralixibat), CHOLBAM® (cholic acid) capsules, and CTEXLI™ (chenodiol) tablets.
LIVMARLI, an IBAT inhibitor, is approved for the treatment of two rare liver diseases affecting children and adults. It is approved for the treatment of cholestatic pruritus in patients with Alagille syndrome in the U.S. (three months and older), in Europe (two months and older), and in other regions globally. It is also approved in the U.S. in cholestatic pruritus in PFIC patients 12 months of age and older; in Europe, it is approved for patients with PFIC three months of age and older. Mirum is also initiating the Phase 3 EXPAND study, a label expansion opportunity for LIVMARLI in additional settings of cholestatic pruritus. CHOLBAM is FDA-approved for the treatment of bile acid synthesis disorders due to single enzyme deficiencies and adjunctive treatment of peroxisomal disorders in patients who show signs or symptoms of liver disease. CTEXLI is FDA-approved for the treatment of cerebrotendinous xanthomatosis (CTX) in adults.
Mirum's late-stage pipeline includes two investigational treatments for several rare diseases. Volixibat, an IBAT inhibitor, is being evaluated in two potentially registrational studies including the Phase 2 VISTAS study for primary sclerosing cholangitis (PSC) and Phase 2b VANTAGE study for primary biliary cholangitis (PBC). Volixibat has been granted Breakthrough Therapy Designation for the treatment of cholestatic pruritus in patients with PBC. Mirum is also planning for a Phase 2 study evaluating MRM-3379, a PDE4D inhibitor for the treatment of Fragile X syndrome, a rare genetic neurocognitive disorder.
To learn more about Mirum, visit mirumpharma.com and follow Mirum on Facebook, LinkedIn, Instagram and X.
View source version on businesswire.com: https://www.businesswire.com/news/home/20250610559917/en/
Contacts
Investor Contact: Andrew McKibbenir@mirumpharma.com
Media Contact: Erin Murphymedia@mirumpharma.com

Orange background

Try Our AI Features

Explore what Daily8 AI can do for you:

Comments

No comments yet...

Related Articles

NewHydrogen's Plan to Win the Green Hydrogen Race
NewHydrogen's Plan to Win the Green Hydrogen Race

Yahoo

time2 hours ago

  • Yahoo

NewHydrogen's Plan to Win the Green Hydrogen Race

SANTA CLARITA, Calif., June 12, 2025 (GLOBE NEWSWIRE) -- NewHydrogen, Inc. (OTCQB: NEWH), developer of ThermoLoop™, a technology that uses water and heat to produce the world's cheapest green hydrogen, today described its plan to replace expensive electrolyzers and win the renewable hydrogen race. NewHydrogen CEO Steve Hill said, 'Today, using electrolyzers is the only commercially available way to split water to produce renewable hydrogen. Electrolyzers have dominated the headlines, but their reign may be coming to an end. The time has come to kill electrolyzers!' 'The renewable hydrogen industry's heavy bet on electrolysis is holding it back,' Mr. Hill continued. 'Why? Because electrolyzers are old tech—expensive, inefficient, and fundamentally flawed. These 200-year-old systems still depend on large amounts of electricity and face major cost and scaling challenges. Despite massive investment, they've struggled to deliver the cost reductions and reliability needed to help unlock the global hydrogen economy.' ThermoLoop is being developed to change that. Instead of electricity, ThermoLoop can use any source of heat to split water into hydrogen and oxygen, making it a fundamentally different, and a more promising approach. By addressing key limitations that have dogged electrolyzers for decades, ThermoLoop has the potential to leapfrog the current state of the art and win the green hydrogen race. At the heart of ThermoLoop is its novel materials and novel reactions that keep the process running at nearly the same temperature—eliminating the energy losses of traditional thermochemical heating and cooling cycles. The Company believes this can overcome a long-standing thermochemical challenge: how to scale without wasting energy. This approach enables continuous, 24/7 hydrogen production wherever there's heat and water. Even when using large industrial heaters powered by electricity, ThermoLoop's theoretical heat-based thermodynamic efficiency suggests it can outperform electrolyzers on a cost-per-kilogram basis. That can make ThermoLoop technology not only an alternative, but a direct threat to the electrolysis-first strategy dominating today's hydrogen buildout. Mr. Hill concluded, 'Relying on inefficient electrolyzer technology won't get us to the projected $12 trillion hydrogen economy. Other horses in the race that rely on massive tracts of land and part-time sunlight won't get us there either. In my opinion, it's ThermoLoop or bust. We believe ThermoLoop can offer a smarter path forward and has the potential to be the key to finally delivering on green hydrogen's global promise.' To watch a short explainer video about ThermoLoop™ or to learn more about NewHydrogen's mission to produce the world's cheapest green hydrogen, visit About NewHydrogen, Inc. NewHydrogen is developing ThermoLoop™ – a breakthrough technology that uses water and heat to produce the world's lowest cost green hydrogen. Hydrogen is the cleanest and most abundant element in the universe, and we can't live without it. Hydrogen is the key ingredient in making fertilizers needed to grow food for the world. It is also used for transportation, refining oil and making steel, glass, pharmaceuticals and more. Nearly all the hydrogen today is made from hydrocarbons like coal, oil, and natural gas, which are dirty and limited resources. Water, on the other hand, is an infinite and renewable worldwide resource. Currently, the most common method of making green hydrogen is to split water into oxygen and hydrogen with an electrolyzer using green electricity produced from solar or wind. However, green electricity is and always will be very expensive. It currently accounts for 73% of the cost of green hydrogen. By using heat directly, we can skip the expensive process of making electricity and fundamentally lower the cost of green hydrogen. Inexpensive heat can be obtained from concentrated solar, geothermal, nuclear reactors and industrial waste heat for use in our novel low-cost thermochemical water splitting process. Working with a world class research team at UC Santa Barbara, our goal is to help usher in the green hydrogen economy that Goldman Sachs estimated to have a future market value of $12 trillion. Safe Harbor Statement Matters discussed in this press release contain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. When used in this press release, the words "anticipate," "believe," "estimate," "may," "intend," "expect" and similar expressions identify such forward-looking statements. Actual results, performance or achievements could differ materially from those contemplated, expressed or implied by the forward-looking statements contained herein. These forward-looking statements are based largely on the expectations of the Company and are subject to a number of risks and uncertainties. These include, but are not limited to, risks and uncertainties associated with: the impact of economic, competitive and other factors affecting the Company and its operations, markets, the impact on the national and local economies resulting from terrorist actions, the impact of public health epidemics on the global economy and other factors detailed in reports filed by the Company with the United States Securities and Exchange Commission. Any forward-looking statement made by us in this press release is based only on information currently available to us and speaks only as of the date on which it is made. We undertake no obligation to publicly update any forward-looking statement, whether written or oral, that may be made from time to time, whether as a result of new information, future developments or otherwise. Investor Relations Contact: NewHydrogen, in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data

Solix Technologies launches Solix ECS AI to enhance enterprise content services
Solix Technologies launches Solix ECS AI to enhance enterprise content services

Business Upturn

time3 hours ago

  • Business Upturn

Solix Technologies launches Solix ECS AI to enhance enterprise content services

By Aman Shukla Published on June 12, 2025, 12:12 IST Solix Technologies, Inc. has announced the release of Solix ECS AI, an upgrade to its existing Enterprise Content Services (Solix ECS) platform. This enhancement integrates large language model (LLM) capabilities, aimed at helping organizations extract actionable insights from unstructured data while maintaining governance and compliance. Solix ECS AI offers several key features, including multi-document Q&A, content summarization, intelligent data extraction, and AI-generated content creation. The platform also supports AI-driven workflows that automate approvals, escalations, and retention policies based on document context. Deployment options include public and private SaaS or on-premises, with flexibility to choose between LLM providers to meet specific performance and security needs. The solution is built using IBM and is now available via SolixCloud or through a license upgrade for existing ECS customers. Aman Shukla is a post-graduate in mass communication . A media enthusiast who has a strong hold on communication ,content writing and copy writing. Aman is currently working as journalist at

DOWNLOAD THE APP

Get Started Now: Download the App

Ready to dive into the world of global news and events? Download our app today from your preferred app store and start exploring.
app-storeplay-store