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Genentech announces final results from OS analysis of Phase III INAVO120 study

Genentech announces final results from OS analysis of Phase III INAVO120 study

Genentech, a member of the Roche (RHHBY) Group, announced positive final results from the overall survival, OS, analysis of the Phase III INAVO120 study. These data showed Itovebi, in combination with palbociclib and fulvestrant, reduced the risk of death by more than 30% compared with palbociclib and fulvestrant alone. This represents a statistically significant and clinically meaningful improvement in overall survival for people with PIK3CA-mutated, hormone receptor-positive, human epidermal growth factor receptor 2-negative, endocrine-resistant, locally advanced or metastatic breast cancer. The results are being presented in an oral session at the 2025 American Society of Clinical Oncology, ASCO, Annual Meeting and simultaneously published in the New England Journal of Medicine, NEJM. The Itovebi-based regimen demonstrated a meaningful OS benefit compared with palbociclib and fulvestrant alone. The median OS was 34.0 months for people in the Itovebi arm, compared with 27.0 months in the palbociclib and fulvestrant arm. The benefit seen in delaying cancer progression was maintained in the updated analysis, with the Itovebi-based regimen showing a consistent improvement in median progression free survival of 17.2 months versus 7.3 months in the comparator arm.
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SergeFerrari Group: Revenue of €178.7 Million in the First Half of 2025
SergeFerrari Group: Revenue of €178.7 Million in the First Half of 2025

Yahoo

time11 minutes ago

  • Yahoo

SergeFerrari Group: Revenue of €178.7 Million in the First Half of 2025

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SergeFerrari Group: Revenue of €178.7 Million in the First Half of 2025
SergeFerrari Group: Revenue of €178.7 Million in the First Half of 2025

Business Wire

time43 minutes ago

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SergeFerrari Group: Revenue of €178.7 Million in the First Half of 2025

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Tech's New Marketing Edge: Empowering Hispanic Voices In STEM
Tech's New Marketing Edge: Empowering Hispanic Voices In STEM

Forbes

timean hour ago

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Tech's New Marketing Edge: Empowering Hispanic Voices In STEM

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The study sheds light on how representation, role models, and targeted initiatives could help bridge this gap and build a more inclusive future. I discussed this topic with Lilli Gil Valletta, an industry leader, Co-Founder and CEO of Culture+ Group, who expressed that: 'The future of the American workforce is already here, and it is Hispanic. This is not about quotas or representation; it is about maintaining our competitiveness as a nation. Today, one in three public school students is from Hispanic origin, and in our largest states—California and Texas—this proportion is one in two. Yet only less than five percent of Silicon Valley's high-tech workforce shares that identity. At a time when Hispanics are driving seventy-eight percent of net U.S. labor force growth, our size and growth still far outpace our presence as creators and innovators in STEM. Bridging this gap isn't just about 'equity'—it's about unlocking America's full economic and innovative potential. There is simply no growing talent pipeline if we don't tap into the segment driving most of the workforce growth.' Below are some initial thoughts on how marketers can leverage some of the conclusions of this study in their day-to-day strategies. 1. The Need for Representation in STEM Seventy-seven percent of Hispanic adults believe that increased representation of Hispanics in STEM would encourage more young people from their community to pursue these careers. Brands in tech, science, and education have an opportunity to feature Hispanic professionals in their marketing campaigns. Showcasing Hispanic engineers, scientists, or tech leaders can inspire the next generation while positioning the brand as a champion of diversity. 2. Addressing Stereotypes and Barriers The study also highlights the persistence of stereotypes and systemic barriers that discourage Hispanic participation in STEM. Many respondents noted that cultural expectations, financial challenges, and a lack of mentorship often deter young Hispanics from pursuing STEM degrees or careers. Brands can use their platforms to tell authentic stories that counteract stereotypes and celebrate Hispanic contributions to STEM fields. Financial barriers remain a significant hurdle for many Hispanic students. Brands that provide scholarships, grants, or paid internships can make a tangible impact. 3. The Role of Media and Marketing in Shaping Perceptions The Pew study report underscores the power of media representation in shaping aspirations. When young Hispanics see themselves represented as innovators, leaders, and problem-solvers, it can spark a sense of possibility and belonging. Representation in advertising is key. Brands should feature Hispanics in STEM-related contexts, whether in commercials, digital ads, or social media campaigns. Partnering with Hispanic influencers who advocate for education and STEM can expand a brand's reach and credibility. 4. Building Trust with Hispanic Communities The report highlights the importance of trust in fostering relationships with Hispanic communities. Authenticity and long-term commitment are essential for brands looking to make a meaningful impact. Brands need to go beyond performative gestures and demonstrate genuine commitment to improving representation and access to STEM opportunities. Transparency is key to building trust. Brands should track the success of their STEM initiatives and share the results with their audiences. 5. The Business Case for Diversity in STEM Diversity is not just a social imperative—it's a business advantage. Research consistently shows that diverse teams drive innovation and improve problem-solving, making the case for greater Hispanic representation in STEM a strategic one. Companies that prioritize diversity in their STEM workforce will attract top Hispanic talent, who are increasingly seeking employers that align with their values. Hispanic consumers are more likely to support brands that demonstrate a commitment to their community. Investing in STEM initiatives is a powerful way to build long-term loyalty. The Pew Research Center study makes it clear that representation matters. For brands and marketers, the call to action is equally clear. By investing in initiatives that promote Hispanic representation in STEM, brands can inspire the next generation of innovators while building trust and loyalty within the Hispanic community. In a world increasingly driven by technology and innovation, the future belongs to those who understand how the demographic changes in America are shaping the labor and consumer markets.

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