Cloud Gaming Market Outlook to 2029 with Microsoft Xbox Cloud Gaming Dominating the $35 Billion Market by Ruling More Than Half of the Market Share
Global Cloud Gaming Market: In 2023, valued at USD 3.8 Bn, is projected to reach USD 35 Bn by 2029, driven by 5G connectivity, consumer adoption, and social features. Dominated by Microsoft Xbox Cloud Gaming, key players include Nvidia GeForce Now, Sony, and Amazon Luna. APAC leads due to China, Japan, and South Korea's influence. The market thrives on rising subscription services, mobile gaming trends, and cross-platform compatibility. Challenges include content licensing and scalability issues.
Dublin, June 09, 2025 (GLOBE NEWSWIRE) -- The "Cloud Gaming Market Outlook to 2029" report has been added to ResearchAndMarkets.com's offering.In 2023, the Global Cloud Gaming Market was valued at USD 3.8 Bn and is forecasted to reach a market size of USD 35 Bn driven by enhancing 5G connectivity, increasing adoption of cloud gaming among consumers, the emergence of Cloud Gaming, and focus on game streaming and social features.The market is highly consolidated with Microsoft Xbox Cloud Gaming dominating the market by ruling more than half of the market share. Other key players in the market include Nvidia GeForce Now, Sony PlayStation Cloud, and Amazon Luna.In 2021, Microsoft introduced a Clarity Boost feature for Windows users, improving the visual quality of streamed content. The service's performance is contingent on internet speed, with recommendations for optimal experiences set at 9 Mbps download speeds and latency below 60 ms.Global Cloud Gaming Current Market AnalysisAPAC as dominant region: The Asia Pacific region is dominating the global cloud gaming market owing to the presence of countries like China, Japan, and South Korea, driven by a large and growing gaming population, advanced infrastructure and technology, and high internet penetration and technological adoption. In 2023, the global number of gaming players reached 3.38 billion, APAC region accounts for more than half of all players worldwide.North America as emerging region: North America is the second largest market for cloud gaming globally driven by its popularity of gaming, increasing penetration of high-speed internet, partnerships and collaborations, and advancements in technology. In 2023, the internet penetration rate in the United States was 93.79%. This figure indicates that out of a population of about 331.9 million, around 311.3 million individuals were internet users.China as the dominant country: China is the leading country in the Asia-Pacific cloud gaming market ruling more than half of the market share followed by Japan, and South Korea. The market in China is driven by government support and investment, high penetration of mobile devices, and strong technology infrastructure. In 2023, nearly 99.9% of internet users in China accessed the web via mobile phones. By 2023, the number of mobile internet users in China had reached 1.09 billion.Global Cloud Gaming Market SegmentationBy Consumer Type: The global cloud gaming market segmentation by consumer type includes enthusiasts and casual gamers. In 2023, casual gamers dominated the market due to their demand for high-quality experiences, such as high-resolution graphics and low latency. They are more likely to invest in premium cloud gaming services and are attracted to exclusive content and advanced features.by Technology: The global cloud gaming market segmentation by technology is classified into video streaming and virtual machines/file streaming. In 2023, video streaming was the dominant technology in the market due to its ability to deliver real-time gaming experiences across various devices, including smartphones, tablets, and smart TVs. Its popularity is driven by advancements in streaming technology that improve performance and reduce latency.Global Cloud Gaming Market Growth Drivers:
Increasing Adoption of Cloud Gaming Among Consumers: Consumers are increasingly adopting and experimenting with cloud gaming services, lured by the capabilities provided by this new technology. By 2029, the number of cloud gaming consumers is anticipated to reach 501.1 Mn users globally. The growth in cloud gaming is attributed to factors such as the proliferation of high-speed internet, the convenience of accessing games without the need for expensive hardware, and the ability to play on various devicesEmergence of Cloud Gaming: The emergence of Cloud Gaming is a significant driver for the growth of the cloud gaming market. By processing data closer to the end-users, Cloud Gaming helps reduce latency, a critical factor for an optimal cloud gaming experience. In 2015, Google Scholar indexed just 720 new papers on Cloud Gaming. By 2023, this number had surged to over 42,700. With the increasing demand for high-performance and low-latency gaming, the adoption of Cloud Gaming is expected to drive substantial growth in the cloud gaming market.Increasing Price of Gaming Hardware: The increasing price of gaming hardware is a significant driver for the growth of the global cloud gaming market, as it offers a more cost-effective alternative for gamers. The average selling price (ASP) of gaming PCs increased by 14.3% in 2022, reaching USD 1,093, compared to USD 956 in 2021. The report attributes this price hike to factors such as higher component costs, supply chain disruptions, and increased demand for high-end gaming rigs.Global Cloud Gaming Market Challenges:Content Licensing and Availability: The limited game library and content availability on cloud gaming platforms compared to traditional gaming platforms can be a significant restraint for the growth of the global cloud gaming market. This lack of content variety stems from the fact that the availability of games on cloud gaming services is contingent upon licensing agreements with game developers and publishers. Exclusive licensing deals or a restricted selection of titles can deter gamers from adopting cloud gaming services due to the reduced appeal caused by the limited content offerings.Lack of Economies of Scale: Currently, cloud gaming providers are focusing on improving scalability, as data processing and transmission requirements can be highly demanding. This is because there is almost a 1 to 1 relationship between the resources required to provide an appropriate cloud gaming service and the number of players subscribed to a service. Unless innovative content delivery software is developed, or data center capabilities substantially improve, cloud gaming companies will have to keep investing massive amounts of capital as userbases keep increasing.Future Market TrendsRise of Subscription Services: The cloud gaming market witnesses a surge in subscription services, exemplified by Xbox Game Pass exceeding 33 million subscribers by the end of 2023 and PlayStation Now surpassing 47 million subscribers in 2023. These platforms offer extensive game libraries for a monthly fee, indicating a shift towards subscription-based gaming models. This trend reflects consumer preference for cost-effective access to diverse gaming content, further driving the adoption of subscription services in the cloud gaming market.Mobile Cloud Gaming and Demand for Cross-Platform Compatibility: The proliferation of smartphones and the rollout of 5G networks drive the surge in mobile cloud gaming, a significant trend in the global market. Users enjoy high-quality gaming without powerful hardware, leveraging cloud gaming platforms. Concurrently, cross-platform compatibility gains traction as providers ensure seamless integration across devices. This convergence enhances convenience and accessibility, allowing gamers to transition effortlessly between devices.Key Topics Covered: 1. Executive Summary1.1 Global Cloud Gaming Market2. Global Overview2.1 Overview of Global Economics2.2 Overview of Global Cloud Gaming Industry2.3 Global Plastics Market3. Global Cloud Gaming Market Overview3.1 Global Cloud Gaming Market Ecosystem3.2 Global Cloud Gaming Market Value Chain4.Global Cloud Gaming Market Size (in USD Bn), 2018-20235. Global Cloud Gaming Market (in value %), 2018-20235.1 Global Cloud Gaming Market Segmentation by Region (in value %), 2018-20235.2 Global Cloud Gaming Market Segmentation by Consumer Type (in value%), 2018-20235.3 Global Cloud Gaming Market Segmentation by Technology Type (in value %), 2018-2023
6.Global Cloud Gaming Market Competition Landscape6.1 Global Cloud Gaming Market Share Analysis6.2 Global Cloud Gaming Market Heat Map Analysis6.3 Global Cloud Gaming Market Cross Comparison6.4 Global Cloud Gaming Market Comparison Matrix
7.Global Cloud Gaming Market Dynamics7.1 Global Cloud Gaming Market Growth Drivers7.2 Global Cloud Gaming Market Challenges7.3 Global Cloud Gaming Market Trends7.4 Global Cloud Gaming Market Case Studies7.5 Global Cloud Gaming Market Strategic Initiatives8. Global Cloud Gaming Future Market Size (in value %), 2023-20288.1 Global Cloud Gaming Future Market Segmentation by Region (in value %), 2023-20288.2 Global Cloud Gaming Future Market Segmentation by Consumer Type (in value%), 2023-20288.3 Global Cloud Gaming Future Market Segmentation by Technology Type (in value %), 2023-20289. Analyst RecommendationsA selection of companies mentioned in this report includes, but is not limited to:
Nvidia
Microsoft
Boosteroid
Amazon Luna
Blacknut
Playstation Now
Shadow Play
For more information about this report visit https://www.researchandmarkets.com/r/6sy0zq
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Provide supportive care and/or corticosteroids as and Guillain-Barré syndrome (GBS) and their associated complications resulting in fatal or life-threatening reactions have occurred following treatment with CARVYKTI ®.Hemophagocytic Lymphohistiocytosis/Macrophage Activation Syndrome (HLH/MAS), including fatal and life-threatening reactions, occurred in patients following treatment with CARVYKTI ®. HLH/MAS can occur with CRS or neurologic and/or recurrent cytopenias with bleeding and infection and requirement for stem cell transplantation for hematopoietic recovery occurred following treatment with CARVYKTI ®.Secondary hematological malignancies, including myelodysplastic syndrome and acute myeloid leukemia, have occurred in patients following treatment with CARVYKTI ®. 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Parkinsonism: Neurologic toxicity with parkinsonism has been reported in clinical trials of CARVYKTI®. Among patients receiving CARVYKTI® in the CARTITUDE-1 & 4 studies, parkinsonism occurred in 3% (8/285), including Grade ≥ 3 in 2% (5/285) of the patients. Median time to onset of parkinsonism was 56 days (range: 14 to 914 days). Parkinsonism resolved in 1 of 8 (13%) of patients with a median time to resolution of 523 days. Median duration of parkinsonism was 243.5 days (range: 62 to 720 days) in all patients including those with ongoing neurologic events at the time of death or data cut-off. The onset of parkinsonism occurred after CRS for all patients and after ICANS for 6 patients. Parkinsonism occurred in 1% of patients in CARTITUDE-4 (no Grade 3 to 4) and in 6% of patients in CARTITUDE-1 (4% Grade 3 to 4). Manifestations of parkinsonism included movement disorders, cognitive impairment, and personality changes. Monitor patients for signs and symptoms of parkinsonism that may be delayed in onset and managed with supportive care measures. There is limited efficacy information with medications used for the treatment of Parkinson's disease for the improvement or resolution of parkinsonism symptoms following CARVYKTI® treatment. Guillain-Barré Syndrome: A fatal outcome following GBS occurred following treatment with CARVYKTI® despite treatment with intravenous immunoglobulins. Symptoms reported include those consistent with Miller-Fisher variant of GBS, encephalopathy, motor weakness, speech disturbances, and polyradiculoneuritis. Monitor for GBS. Evaluate patients presenting with peripheral neuropathy for GBS. Consider treatment of GBS with supportive care measures and in conjunction with immunoglobulins and plasma exchange, depending on severity of GBS. Immune Mediated Myelitis: Grade 3 myelitis occurred 25 days following treatment with CARVYKTI® in CARTITUDE-4 in a patient who received CARVYKTI® as subsequent therapy. Symptoms reported included hypoesthesia of the lower extremities and the lower abdomen with impaired sphincter control. Symptoms improved with the use of corticosteroids and intravenous immune globulin. Myelitis was ongoing at the time of death from other cause. Peripheral Neuropathy occurred following treatment with CARVYKTI®. Among patients receiving CARVYKTI® in the CARTITUDE-1 & 4 studies, peripheral neuropathy occurred in 7% (21/285), including Grade ≥3 in 1% (3/285) of the patients. Median time to onset of peripheral neuropathy was 57 days (range: 1 to 914 days). Peripheral neuropathy resolved in 11 of 21 (52%) of patients with a median time to resolution of 58 days (range: 1 to 215 days). Median duration of peripheral neuropathy was 149.5 days (range: 1 to 692 days) in all patients including those with ongoing neurologic events at the time of death or data cut-off. Peripheral neuropathies occurred in 7% of patients in CARTITUDE-4 (0.5% Grade 3 to 4) and in 7% of patients in CARTITUDE-1 (2% Grade 3 to 4). Monitor patients for signs and symptoms of peripheral neuropathies. Patients who experience peripheral neuropathy may also experience cranial nerve palsies or GBS. Cranial Nerve Palsies occurred following treatment with CARVYKTI®. Among patients receiving CARVYKTI® in the CARTITUDE-1 & 4 studies, cranial nerve palsies occurred in 7% (19/285), including Grade ≥3 in 1% (1/285) of the patients. Median time to onset of cranial nerve palsies was 21 days (range: 17 to 101 days). Cranial nerve palsies resolved in 17 of 19 (89%) of patients with a median time to resolution of 66 days (range: 1 to 209 days). Median duration of cranial nerve palsies was 70 days (range: 1 to 262 days) in all patients including those with ongoing neurologic events at the time of death or data cut-off. Cranial nerve palsies occurred in 9% of patients in CARTITUDE-4 (1% Grade 3 to 4) and in 3% of patients in CARTITUDE-1 (1% Grade 3 to 4). The most frequent cranial nerve affected was the 7th cranial nerve. Additionally, cranial nerves III, V, and VI have been reported to be affected. Monitor patients for signs and symptoms of cranial nerve palsies. Consider management with systemic corticosteroids, depending on the severity and progression of signs and symptoms. HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS (HLH)/MACROPHAGE ACTIVATION SYNDROME (MAS): Among patients receiving CARVYKTI® in the CARTITUDE-1 & 4 studies, HLH/MAS occurred in 1% (3/285) of patients. All events of HLH/MAS had onset within 99 days of receiving CARVYKTI®, with a median onset of 10 days (range: 8 to 99 days) and all occurred in the setting of ongoing or worsening CRS. The manifestations of HLH/MAS included hyperferritinemia, hypotension, hypoxia with diffuse alveolar damage, coagulopathy and hemorrhage, cytopenia, and multi-organ dysfunction, including renal dysfunction and respiratory failure. Patients who develop HLH/MAS have an increased risk of severe bleeding. Monitor hematologic parameters in patients with HLH/MAS and transfuse per institutional guidelines. Fatal cases of HLH/MAS occurred following treatment with CARVYKTI®. HLH is a life-threatening condition with a high mortality rate if not recognized and treated early. Treatment of HLH/MAS should be administered per institutional standards. CARVYKTI® REMS: Because of the risk of CRS and neurologic toxicities, CARVYKTI® is available only through a restricted program under a Risk Evaluation and Mitigation Strategy (REMS) called the CARVYKTI® REMS. Further information is available at or 1-844-672-0067. PROLONGED AND RECURRENT CYTOPENIAS: Patients may exhibit prolonged and recurrent cytopenias following lymphodepleting chemotherapy and CARVYKTI® infusion. Among patients receiving CARVYKTI® in the CARTITUDE-1 & 4 studies, Grade 3 or higher cytopenias not resolved by day 30 following CARVYKTI® infusion occurred in 62% (176/285) of the patients and included thrombocytopenia 33% (94/285), neutropenia 27% (76/285), lymphopenia 24% (67/285) and anemia 2% (6/285). After Day 60 following CARVYKTI® infusion 22%, 20%, 5%, and 6% of patients had a recurrence of Grade 3 or 4 lymphopenia, neutropenia, thrombocytopenia, and anemia respectively, after initial recovery of their Grade 3 or 4 cytopenia. Seventy-seven percent (219/285) of patients had one, two, or three or more recurrences of Grade 3 or 4 cytopenias after initial recovery of Grade 3 or 4 cytopenia. Sixteen and 25 patients had Grade 3 or 4 neutropenia and thrombocytopenia, respectively, at the time of death. Monitor blood counts prior to and after CARVYKTI® infusion. Manage cytopenias with growth factors and blood product transfusion support according to local institutional guidelines. INFECTIONS: CARVYKTI® should not be administered to patients with active infection or inflammatory disorders. Severe, life-threatening, or fatal infections, occurred in patients after CARVYKTI® infusion. Among patients receiving CARVYKTI® in the CARTITUDE-1 & 4 studies, infections occurred in 57% (163/285), including ≥Grade 3 in 24% (69/285) of patients. Grade 3 or 4 infections with an unspecified pathogen occurred in 12%, viral infections in 6%, bacterial infections in 5%, and fungal infections in 1% of patients. Overall, 5% (13/285) of patients had Grade 5 infections, 2.5% of which were due to COVID-19. Patients treated with CARVYKTI® had an increased rate of fatal COVID-19 infections compared to the standard therapy arm. Monitor patients for signs and symptoms of infection before and after CARVYKTI® infusion and treat patients appropriately. Administer prophylactic, pre-emptive, and/or therapeutic antimicrobials according to the standard institutional guidelines. Febrile neutropenia was observed in 5% of patients after CARVYKTI® infusion and may be concurrent with CRS. In the event of febrile neutropenia, evaluate for infection and manage with broad-spectrum antibiotics, fluids, and other supportive care, as medically indicated. Counsel patients on the importance of prevention measures. Follow institutional guidelines for the vaccination and management of immunocompromised patients with COVID-19. Viral Reactivation: Hepatitis B virus (HBV) reactivation, in some cases resulting in fulminant hepatitis, hepatic failure, and death, can occur in patients with hypogammaglobulinemia. Perform screening for Cytomegalovirus (CMV), HBV, hepatitis C virus (HCV), human immunodeficiency virus (HIV), or any other infectious agents if clinically indicated in accordance with clinical guidelines before collection of cells for manufacturing. Consider antiviral therapy to prevent viral reactivation per local institutional guidelines/clinical practice. HYPOGAMMAGLOBULINEMIA: can occur in patients receiving treatment with CARVYKTI®. Among patients receiving CARVYKTI® in the CARTITUDE-1 & 4 studies, hypogammaglobulinemia adverse event was reported in 36% (102/285) of patients; laboratory IgG levels fell below 500mg/dl after infusion in 93% (265/285) of patients. Hypogammaglobulinemia either as an adverse reaction or laboratory IgG level below 500mg/dl, after infusion occurred in 94% (267/285) of patients treated. Fifty-six percent (161/285) of patients received intravenous immunoglobulin (IVIG) post CARVYKTI® for either an adverse reaction or prophylaxis. Monitor immunoglobulin levels after treatment with CARVYKTI® and administer IVIG for IgG <400 mg/dL. Manage per local institutional guidelines, including infection precautions and antibiotic or antiviral prophylaxis. Use of Live Vaccines: The safety of immunization with live viral vaccines during or following CARVYKTI® treatment has not been studied. Vaccination with live virus vaccines is not recommended for at least 6 weeks prior to the start of lymphodepleting chemotherapy, during CARVYKTI® treatment, and until immune recovery following treatment with CARVYKTI®. HYPERSENSITIVITY REACTIONS occurred following treatment with CARVYKTI®. Among patients receiving CARVYKTI® in the CARTITUDE-1 & 4 studies, hypersensitivity reactions occurred in 5% (13/285), all of which were ≤ Grade 2. Manifestations of hypersensitivity reactions included flushing, chest discomfort, tachycardia, wheezing, tremor, burning sensation, non-cardiac chest pain, and pyrexia. Serious hypersensitivity reactions, including anaphylaxis, may be due to the dimethyl sulfoxide (DMSO) in CARVYKTI®. Patients should be carefully monitored for 2 hours after infusion for signs and symptoms of severe reaction. Treat promptly and manage patients appropriately according to the severity of the hypersensitivity reaction. SECONDARY MALIGNANCIES: Patients treated with CARVYKTI® may develop secondary malignancies. Among patients receiving CARVYKTI® in the CARTITUDE-1 & 4 studies, myeloid neoplasms occurred in 5% (13/285) of patients (9 cases of myelodysplastic syndrome, 3 cases of acute myeloid leukemia, and 1 case of myelodysplastic syndrome followed by acute myeloid leukemia). The median time to onset of myeloid neoplasms was 447 days (range: 56 to 870 days) after treatment with CARVYKTI®. Ten of these 13 patients died following the development of myeloid neoplasms; 2 of the 13 cases of myeloid neoplasm occurred after initiation of subsequent antimyeloma therapy. Cases of myelodysplastic syndrome and acute myeloid leukemia have also been reported in the post-marketing setting. T-cell malignancies have occurred following treatment of hematologic malignancies with BCMA- and CD19-directed genetically modified autologous T-cell immunotherapies, including CARVYKTI®. Mature T-cell malignancies, including CAR-positive tumors, may present as soon as weeks following infusions and may include fatal outcomes. Monitor life-long for secondary malignancies. In the event that a secondary malignancy occurs, contact Janssen Biotech, Inc. at 1-800-526-7736 for reporting and to obtain instructions on collection of patient samples. EFFECTS ON ABILITY TO DRIVE AND USE MACHINES: Due to the potential for neurologic events, including altered mental status, seizures, neurocognitive decline, or neuropathy, patients receiving CARVYKTI® are at risk for altered or decreased consciousness or coordination in the 8 weeks following CARVYKTI® infusion. Advise patients to refrain from driving and engaging in hazardous occupations or activities, such as operating heavy or potentially dangerous machinery during this initial period, and in the event of new onset of any neurologic REACTIONS The most common nonlaboratory adverse reactions (incidence greater than 20%) are pyrexia, cytokine release syndrome, hypogammaglobulinemia, hypotension, musculoskeletal pain, fatigue, infections-pathogen unspecified, cough, chills, diarrhea, nausea, encephalopathy, decreased appetite, upper respiratory tract infection, headache, tachycardia, dizziness, dyspnea, edema, viral infections, coagulopathy, constipation, and vomiting. The most common Grade 3 or 4 laboratory adverse reactions (incidence greater than or equal to 50%) include lymphopenia, neutropenia, white blood cell decreased, thrombocytopenia, and anemia. Please read full Prescribing Information, including Boxed Warning, for CARVYKTI®. ABOUT CARVYKTI® (CILTACABTAGENE AUTOLEUCEL; CILTA-CEL) Ciltacabtagene autoleucel is a BCMA-directed, genetically modified autologous T-cell immunotherapy, which involves reprogramming a patient's own T-cells with a transgene encoding a chimeric antigen receptor (CAR) that identifies and eliminates cells that express BCMA. The cilta-cel CAR protein features two BCMA-targeting single domain antibodies designed to confer high avidity against human BCMA. Upon binding to BCMA-expressing cells, the CAR promotes T-cell activation, expansion, and elimination of target cells.1 In December 2017, Legend Biotech entered into an exclusive worldwide license and collaboration agreement with Janssen Biotech, Inc. (Janssen), a Johnson & Johnson company, to develop and commercialize cilta-cel. In February 2022, cilta-cel was approved by the U.S. Food and Drug Administration (FDA) under the brand name CARVYKTI® for the treatment of adults with relapsed or refractory multiple myeloma. In April 2024, cilta-cel was approved for the second-line treatment of patients with relapsed/refractory myeloma who have received at least one prior line of therapy including a proteasome inhibitor, an immunomodulatory agent, and are refractory to lenalidomide. In May 2022, the European Commission (EC) granted conditional marketing authorization of CARVYKTI® for the treatment of adults with relapsed and refractory multiple myeloma. In September 2022, Japan's Ministry of Health, Labour and Welfare (MHLW) approved CARVYKTI®. Cilta-cel was granted Breakthrough Therapy Designation in the U.S. in December 2019 and in China in August 2020. In addition, cilta-cel received a PRIority MEdicines (PRIME) designation from the European Commission in April 2019. Cilta-cel also received Orphan Drug Designation from the U.S. FDA in February 2019, from the European Commission in February 2020, and from the Pharmaceuticals and Medicinal Devices Agency (PMDA) in Japan in June 2020. In March 2022, the European Medicines Agency's Committee for Orphan Medicinal Products recommended by consensus that the orphan designation for cilta-cel be maintained on the basis of clinical data demonstrating improved and sustained complete response rates following treatment. ABOUT CARTITUDE-1 CARTITUDE-1 (NCT03548207) is a Phase 1b/2, open-label, multicenter study evaluating the safety and efficacy of cilta-cel in adults with relapsed and/or refractory with multiple myeloma who have received at least 3 prior lines of therapy or are double refractory to a PI and IMiD, received a PI, an IMiD, and anti-CD38 antibody and documented disease progression within 12 months of starting the most recent therapy. The primary objective of the Phase 1b portion of the study was to characterize the safety and confirm the recommended Phase 2 dose of cilta-cel, informed by the first-in-human study with LCAR-B38M CAR-T cells (LEGEND-2). The Phase 2 portion further evaluated the efficacy of cilta-cel with overall response rate as the primary endpoint.2 ABOUT CARTITUDE-4 CARTITUDE-4 (NCT04181827) is an ongoing, international, randomized, open-label Phase 3 study evaluating the efficacy and safety of cilta-cel versus pomalidomide, bortezomib and dexamethasone (PVd) or daratumumab, pomalidomide and dexamethasone (DPd) in adult patients with relapsed and lenalidomide-refractory multiple myeloma who received one to three prior lines of therapy, including a PI and an IMiD.3 ABOUT LB1908 NCT05539430 is a Phase 1, open label, dose escalation, multicenter study to evaluate Claudin 18.2-targeting CAR-T cells (LB1908) in adult patients with unresectable, locally advanced or metastatic gastric, gastroesophageal junction, esophageal, or pancreatic adenocarcinoma.4 ABOUT LB2102 NCT05680922 is a Phase 1, first-in-human, open-label, multicenter, dose escalation and expansion study of DLL3-targeted chimeric antigen receptor T-cells (LB2102) in patients with extensive stage small cell lung cancer or large cell neuroendocrine lung cancer.5 ABOUT MULTIPLE MYELOMA Multiple myeloma is an incurable blood cancer that starts in the bone marrow and is characterized by an excessive proliferation of plasma cells.6 In 2024, it is estimated that more than 35,000 people will be diagnosed with multiple myeloma, and more than 12,000 people will die from the disease in the U.S.7 While some patients with multiple myeloma initially have no symptoms, most patients are diagnosed due to symptoms that can include bone problems, low blood counts, calcium elevation, kidney problems or infections.8 ABOUT GASTRIC, ESOPHAGEAL AND PANCREATIC CANCERS Stomach, esophageal and pancreatic cancers affect the tissue or glands lining these organs. They are often diagnosed when the diseases have progressed to advanced stages. In the U.S., there are an estimated 123,920 people living with stomach cancer and 49,084 living with esophageal cancers.9,10 An estimated 89,248 people in the U.S. live with pancreatic cancer. While all three cancers are treatable, the five-year survival rate is just 32% for gastric cancer; 20% for esophageal cancer; and 11.5% for pancreatic cancer, with definitive treatment at all stages of progression.11,12,13 ABOUT SMALL CELL LUNG CANCER Lung cancer is a leading cause of cancer deaths, contributing to 25 percent of all cancer-related fatalities annually in the United States.14 Small cell lung cancer (SCLC) is the most aggressive, and accounts for roughly 10-15 percent of lung cancer cases in the United States.15,16 An estimated 30,000 to 35,000 people are newly diagnosed with the disease each year.16 This cancer becomes more difficult to treat once it has spread and becomes extensive stage SCLC. Approximately 60 to 70 percent of SCLC patients are diagnosed with metastatic SCLC.15,17 ABOUT LEGEND BIOTECH With over 2,600 employees, Legend Biotech is the largest standalone cell therapy company and a pioneer in treatments that change cancer care forever. The company is at the forefront of the CAR-T cell therapy revolution with CARVYKTI®, a one-time treatment for relapsed or refractory multiple myeloma, which it develops and markets with collaborator Johnson & Johnson. Centered in the US, Legend is building an end-to-end cell therapy company by expanding its leadership to maximize CARVYKTI's patient access and therapeutic potential. From this platform, the company plans to drive future innovation across its pipeline of cutting-edge cell therapy modalities. Learn more at and follow us on X (formerly Twitter) and LinkedIn. CAUTIONARY NOTE REGARDING FORWARD-LOOKING STATEMENTS Statements in this press release about future expectations, plans, and prospects, as well as any other statements regarding matters that are not historical facts, constitute 'forward-looking statements' within the meaning of The Private Securities Litigation Reform Act of 1995. These statements include, but are not limited to, statements relating to Legend Biotech's strategies and objectives; statements relating to CARVYKTI®, including Legend Biotech's expectations for CARVYKTI® and its therapeutic potential; statements related to the potential results from ongoing studies in the CARTITUDE clinical development program; and the potential benefits of Legend Biotech's product candidates. The words 'anticipate,' 'believe,' 'continue,' 'could,' 'estimate,' 'expect,' 'intend,' 'may,' 'plan,' 'potential,' 'predict,' 'project,' 'should,' 'target,' 'will,' 'would' and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Actual results may differ materially from those indicated by such forward-looking statements as a result of various important factors. Legend Biotech's expectations could be affected by, among other things, uncertainties involved in the development of new pharmaceutical products; unexpected clinical trial results, including as a result of additional analysis of existing clinical data or unexpected new clinical data; unexpected regulatory actions or delays, including requests for additional safety and/or efficacy data or analysis of data, or government regulation generally; unexpected delays as a result of actions undertaken, or failures to act, by our third party partners; uncertainties arising from challenges to Legend Biotech's patent or other proprietary intellectual property protection, including the uncertainties involved in the U.S. litigation process; government, industry, and general product pricing and other political pressures; as well as the other factors discussed in the 'Risk Factors' section of Legend Biotech's Annual Report on Form 20-F filed with the Securities and Exchange Commission on March 11, 2025. Should one or more of these risks or uncertainties materialize, or should underlying assumptions prove incorrect, actual results may vary materially from those described in this press release as anticipated, believed, estimated or expected. Any forward-looking statements contained in this press release speak only as of the date of this press release. Legend Biotech specifically disclaims any obligation to update any forward-looking statement, whether as a result of new information, future events or otherwise. ‡ Sundar Jagannath, M.D., Network Director, Multiple Myeloma Center of Excellence for Multiple Myeloma at The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, has provided consulting, advisory, and speaking services to Legend Biotech; has not been paid for any media work. INVESTOR CONTACT: Jessie YeungTel: (732) 956-8271 PRESS CONTACT: MaryAnn OndishTel: (914) 552-4625media@ REFERENCES _____________________ 1 CARVYKTI™ Prescribing Information. Horsham, PA: Janssen Biotech, Inc.2 A Study of JNJ-68284528, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against B-Cell Maturation Antigen (BCMA) in Participants With Relapsed or Refractory Multiple Myeloma (CARTITUDE-1). Available at: Accessed October 2022.3 A Study Comparing JNJ-68284528, a CAR-T Therapy Directed Against B-cell Maturation Antigen (BCMA), Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) or Daratumumab, Pomalidomide and Dexamethasone (DPd) in Participants With Relapsed and Lenalidomide-Refractory Multiple Myeloma (CARTITUDE-4). Accessed March 2024.4 Claudin 18.2-Targeted Chimeric Antigen Receptor T-cells in Subjects With Unresectable, Locally Advanced, or Metastatic Gastric, Gastroesophageal Junction (GEJ), Esophageal, or Pancreatic Adenocarcinoma. Available at: Accessed May 20255 DLL3-Directed Chimeric Antigen Receptor T-cells in Subjects With Extensive Stage Small Cell Lung Cancer. Available at: Accessed May 20256 American Cancer Society. 'What is Multiple Myeloma?'. Available at: Accessed March 2024.7 American Cancer Society. 'Key Statistics About Multiple Myeloma.' Available at: Accessed March 20248 American Cancer Society. Multiple myeloma: early detection, diagnosis, and staging. Available at: Accessed March 2023.9 Surveillance, Epidemiology, and End Results (SEER) Program. Accessed May 2022.10 Surveillance, Epidemiology, and End Results (SEER) Program. Accessed May 2022.11 American Cancer Society. Accessed May 2022.12 American Cancer Society. May 2022.13 Surveillance, Epidemiology, and End Results (SEER) Program. Accessed May 2022.14 American Cancer Society. 'Key Statistics for Lung Cancer.' Accessed November 2022.15 Byers LA, Rudin CM. Small cell lung cancer: where do we go from here? Cancer. 2015;121(5):664-72.16 Rare Diseases. 'Rare Disease Database.' Accessed November 2022.17 Gong J, Salgia R. Managing patients with relapsed small-cell lung cancer. J Oncol Pract. 2018;14(6): in to access your portfolio
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Sony Music Publishing Acquires Hipgnosis Songs Group
Sony Music Publishing has acquired Recognition Music Group's publishing and administration company Hipgnosis Songs Group, The Hollywood Reporter has confirmed. The acquisition comes five years after Recognition Music Group — which used to be known as Hipgnosis Songs Fund until the company rebranded three months ago — purchased music publisher Big Deal Music in 2020, rebranding that company as Hipgnosis Songs Group shortly after. Hipgnosis Songs has stakes in hits like Alex Warren's 'Ordinary,' and Sabrina Carpenter's 'Espresso' and 'Bed Chem' among others. The publishing company is the only asset Sony acquired from Recognition. More from The Hollywood Reporter 'Boy George & Culture Club' Review: An Affectionate Look at the '80s Band and Its Flamboyant Frontman That Entertains but Treads Too Carefully Trump's Trade War Will Loom Large Over the Banff World Media Fest HBO's 'Harry Potter' Casts 9 More Roles, Including Draco Malfoy Recognition Music was originally founded by music executive Merck Mercuriadis, with Mercuriadis leaving last year after private equity company Blackstone purchased the company. Recognition had been a major driver in the music acquisition boom of the past six years, with the company buying up catalogs from superstars like Justin Bieber, Neil Young, Mark Ronson, the Red Hot Chili Peppers and Shakira among others. Those were not part of the Sony acquisition, and Recognition still owns those catalogs. The news was first reported by Billboard. In an email addressed to Hipgnosis's songwriters, composers and clients and obtained by THR, Sony said it was acquiring Hipgnosis Songs Group 'effective immediately,' and that 'over the next few months, we will be transitioning the company to SMP's services and systems.' 'With a unique roster of contemporary songwriters and timeless classics, HSG aligns with SMP's mission to elevate and support the work of the world's most impactful songwriters, and we are honored to represent you and your songs,' Sony wrote. As the transition begins, writers' royalty payments will continue to be administered through Hipgnosis for now, Sony said. 'We look forward to working with you in this next chapter,' Sony said. Read the full email below: Dear Hipgnosis Songs Group Songwriters, Composers and Clients:On behalf of Sony Music Publishing ('SMP'), we are pleased to inform you that Sony Music Publishing has entered into an agreement with Recognition Music Group ('RMG') to acquire its subsidiary Hipgnosis Songs Group ('HSG'), effective immediately. With this agreement, Sony Music Publishing now owns and administers the Hipgnosis Songs Group catalog, serving as the full-service publisher for its clients and roster of songwriters globally. With a unique roster of contemporary songwriters and timeless classics, HSG aligns with SMP's mission to elevate and support the work of the world's most impactful songwriters, and we are honored to represent you and your the next few months, we will be transitioning the company to SMP's services and systems. We are working closely with HSG to ensure that all clients will receive the high level of service that you have come to expect. No further action is required from you at this the meantime, your current HSG team remains available to address questions or creative inquiries. You can also reach HSG at HSGcreativeteam@ For the time being, your royalty payments will continue to be processed and distributed through HSG's system and your current account access remains unchanged. We will reach out to you directly with important transition updates as they more information, you may contact our team by emailing SMP_HSGsupport@ or by calling our royalty hotline at 615-726-8326. Additional songwriter resources can also be found at you. We look forward to working with you in this next Sony Music Publishing Team Best of The Hollywood Reporter Most Anticipated Concert Tours of 2025: Beyoncé, Billie Eilish, Kendrick Lamar & SZA, Sabrina Carpenter and More Hollywood's Most Notable Deaths of 2025 Hollywood's Highest-Profile Harris Endorsements: Taylor Swift, George Clooney, Bruce Springsteen and More
