logo
Scientists just designed the perfect cacio e pepe recipe

Scientists just designed the perfect cacio e pepe recipe

Fast Company06-05-2025

Chances are, if you're not an Italian grandma or a skilled home chef from Rome, you've probably messed up while trying to make cacio e pepe. At least, that's the thesis underpinning the scientific study ' Phase behavior of Cacio e Pepe sauce,' published on April 29 in the journal Physics of Fluids.
The study—conducted by a group of scientists from the University of Barcelona, the Max Planck Institute for the Physics of Complex Systems in Germany, the University of Padova in Italy, and the Institute of Science and Technology Austria—is pretty much what its title suggests: a full-on scientific investigation into the most 'optimized recipe' for the creamy, peppery pasta dish.
'We're Italians living abroad, and we often get together for dinner to enjoy traditional recipes from home,' says Ivan Di Terlizzi, the study's lead author and a postdoctoral researcher at the Max Planck Institute. 'Among the dishes we've cooked, cacio e pepe came up several times, and every time, we were struck by how hard it is to get the sauce right. That's when we realized it might actually be an interesting physical system to study. And of course, there was also the very practical motivation of avoiding the heartbreak of wasting good pecorino!'
A very brief history of pasta-based physics experiments
This isn't the first time that pasta has been used as inspiration for physicists. Probably the most famous example of 'pasta as experiment,' Di Terlizzi says, is the observation that spaghetti almost never breaks cleanly in half, tending to snap into three or more fragments instead. This fact originally puzzled renowned physicist Richard Feynman (who died in 1988) and wasn't fully explained until 2005, when a team of French physicists showed that it's caused by cascading cracks traveling along the pasta.
Another example, Di Terlizzi adds, is the physics of ring-shaped polymers, which are 'notoriously hard to understand.' A study in 2014 used a type of circular pasta, which the researchers called 'anelloni,' to explain why these looped polymers behave so strangely in experiments. With cacio e pepe, the physics question of interest has to do with the sauce's unusual behavior under heat.
'The main goal of our work wasn't just culinary; it was to explore the physics of this system,' Di Terlizzi says. 'The sauce's behavior under heat shares features with many physical and biological phenomena, like phase transitions or the formation of membrane-less organelles inside cells. The recipe is, in a sense, the practical byproduct of everything we learned.'
The most optimal cacio e pepe recipe, according to scientists
Cacio e pepe traditionally only includes three ingredients: pasta, pecorino Romano cheese, and black pepper. While it seems like a simple enough concoction, the sauce's creamy smoothness (the backbone of the dish) can be quite finicky to achieve. When the temperature gets too high or the mixing of cheese and pasta water isn't done carefully, the cheese proteins will denature—essentially 'unfolding' and losing their normal 3D structure.
In the unfolded state, the proteins then stick together and the emulsion breaks. 'Instead of a creamy consistency, you get a gooey mess, which we call salsa impazzita. . . that is, crazy sauce,' Di Terlizzi says. The physics-based solution to 'crazy sauce'? It's all about starch.
It turns out that, by perfecting the ratio of starch in the pasta water to cheese mass, the cacio e pepe sauce becomes far more resistant to heat, which stabilizes the emulsion and prevents clumping.
'Without starch, the so-called 'mozzarella phase' kicks in at around 65°C, where the proteins start forming large aggregates,' Di Terlizzi says. 'But if the starch concentration is above 1% relative to the cheese mass, the clumps stay small, and temperature becomes much less critical, making it much easier to get a good result.' This is similar to using polymers to stabilize emulsions in soft matter physics, he adds.
'Phase behavior of cacio e pepe sauce' contains ultra-detailed steps to a foolproof cacio e pepe, but here are the instructions in condensed terms:
Step 1: For a pasta dish for 'two hungry people,' start with 300 grams of the preferred tonnarelli pasta—or opt for spaghetti or rigatoni, if you must. From there, you'll need 200 grams of cheese. 'Traditionalists would insist on using only pecorino Romano DOP [protected designation of origin], but some argue that up to 30% parmigiano Reggiano DOP is acceptable; though this remains a point of debate,' the recipe notes. Proceed based on your own personally held cheese preferences.
Step 2: To prepare the sauce, dissolve 5 grams of starch—like potato or corn starch—in 50 grams of water. Heat this mixture gently until it thickens and turns from cloudy to nearly clear. This is your starch gel.
Step 3: Add 100 grams of water to the starch gel. Instead of manually grating the cheese into the resulting liquid, blend the two together to achieve a homogeneous sauce. Finish the sauce by adding black pepper to taste (for best results, toast the pepper in a pan before adding).
Step 4: To prepare the pasta, cook in slightly salted water until it is al dente. Save some of the pasta cooking water before draining. Once the pasta has been drained, let it cool down for up to a minute to prevent the excessive heat from destabilizing the sauce. Finally, mix the pasta with the sauce, ensuring even coating, and adjust the consistency by gradually adding reserved pasta water as needed.

Orange background

Try Our AI Features

Explore what Daily8 AI can do for you:

Comments

No comments yet...

Related Articles

Étienne-Émile Baulieu, ‘father of the abortion pill,' dies at 98
Étienne-Émile Baulieu, ‘father of the abortion pill,' dies at 98

Boston Globe

time4 hours ago

  • Boston Globe

Étienne-Émile Baulieu, ‘father of the abortion pill,' dies at 98

'I do not like abortion,' Dr. Baulieu wrote in his 1991 book, 'The Abortion Pill,' written with journalist Mort Rosenblum. 'But neither do I believe that women should be deprived of their most fundamental rights.' Dr. Baulieu, who specialized in hormone research at a French government lab, had already by the 1970s made one breakthrough discovery relating to a hormone and certain health risks. He next sought to explore new birth control methods, nearly two decades after the first oral contraceptive, Enovid, was approved for use in the United States in 1960. Get Starting Point A guide through the most important stories of the morning, delivered Monday through Friday. Enter Email Sign Up Dr. Baulieu narrowed his research to sex hormones, particularly progesterone, which is essential to pregnancy because it prepares the uterus for a newly fertilized egg. Advertisement He knew that the French drug company Roussel-Uclaf — where he was a consultant on drug development — would not invest in a sex-hormone drug linked to birth control. Instead, he nudged the company to support work on a molecular compound to block cortisone, a hormone involved in blood sugar regulation, metabolism, and suppressing inflammation. Advertisement The key for Dr. Baulieu was that cortisone had a chemical structure similar to that of progesterone. Dr. Baulieu suggested that a cortisone-blocking agent, called an anti-glucocorticoid, could be useful for the treatment of burns, wounds, and glaucoma. Privately, he also hoped it would act as an anti-progesterone and prove effective in terminating early pregnancies without the need for surgery. In 1980, Roussel-Uclaf chemist Georges Teutsch synthesized RU-38486, or the 38,486th compound created at the company's labs. The compound — its molecular name shortened to RU-486 — was found to block the function of progesterone and cortisone, as Dr. Baulieu anticipated. He ultimately persuaded the company to pursue human abortion trials. He first, however, had to make the case that RU-486 was safe. Toxicity tests had caused three monkeys to become so ill that they had to be euthanized. Dr. Baulieu argued that the drug was working as it should, but that the monkeys were given doses that were too high. He told the Observer, a British newspaper, that he had 'rescued RU-486 from oblivion.' After clinical trials — first in Switzerland, then in Hungary and Sweden — Roussel-Uclaf received French approval in 1988 to market the drug to end pregnancies up to 10 weeks after a missed menstrual period. RU-486 (whose generic name is mifepristone and which was marketed as mifeprex in the United States) is followed within 48 hours by a drug known as misoprostol to induce uterine contractions. The two drugs are supposed to be prescribed by a physician and can be taken at home without medical supervision. RU-486 was the product of a team effort, but Dr. Baulieu was seen as the drug's key architect and advocate. He became known as 'the father of the abortion pill' and was a reviled target of antiabortion activists and others. Advertisement The Vatican in 1997 denounced RU-486 as 'the pill of Cain: the monster that cynically kills its brothers.' In Canada, a billboard once displayed Dr. Baulieu's picture and the words, 'Wanted for genocide.' In 1988, he was protected by bodyguards during a trip to the United States. But he also said he received messages of thanks from women who were able to end their pregnancies without a surgical procedure. In France, the antiabortion sentiment was so strong that Roussel-Uclaf halted production of the drug soon after it was approved for distribution. Protests raged outside Roussel-Uclaf headquarters in Paris. 'You are turning the uterus into a crematory oven,' demonstrators yelled, alluding to the production of poison gas for Nazi Germany by a predecessor of Hoechst, the holding company that owned Roussel-Uclaf. With drug production on hold, Dr. Baulieu traveled to Brazil for a medical conference that turned into a 'pep rally' for RU-486, the New York Times reported. By the end of the conference, the drug was reinstated by Roussel-Uclaf. Claude Évin, then health minister of France, had declared that RU-486 was 'the moral property of women.' 'Before we left Rio,' Dr. Baulieu wrote in his book, 'we opened the champagne.' The FDA approved mifepristone (pronounced mi-fuh-PRI-stone) in 2000, more than a decade after it became available in China and in Russia and other parts of Europe. (U.S. research into the drug as an abortion medication had been banned, but it was studied as a treatment for hormonal disorders including Cushing's syndrome.) The drug's delay in the United States came from fear of boycotts against Hoechst and a heavily politicized climate around the approval process. Advertisement Since Roe v. Wade and its protection of U.S. abortion rights were overturned in 2022, mifepristone has been at the center of legal questions over whether antiabortion states can block the Postal Service from delivering the drug. Mifepristone is used in more than 60 percent of abortions in the United States, according to the Guttmacher Institute, a research and policy group focusing on reproductive health. 'Ideology and machismo, alas, weigh more heavily than rationality and scientific proof,' Dr. Baulieu told the New Yorker in 2022. 'A method that makes the termination of pregnancy less physically traumatic for women and less risky to their health has always been rejected by pro-lifers: What they really seek is to harm and punish women.' He often recounted an incident from his medical residency in Paris in the 1950s. A surgeon, scraping the uterus of a woman who had self-administered an abortion, refused to render her unconscious with general anesthesia, remarking that it would 'teach her a lesson she will remember,' he said. As an authority on reproduction, Dr. Baulieu became part of a government committee that helped change French law in 1967 to allow the birth control pill. Later, during a visit to India in 1970, Dr. Baulieu was shaken when a woman begging for money shoved the body of her dead child at him. 'During that trip,' Dr. Baulieu recalled, 'I decided to aim my life's work toward finding some way to ease this sort of suffering.'

French scientist Etienne-Emile Baulieu, inventor of the abortion pill, dies at 98

time5 hours ago

French scientist Etienne-Emile Baulieu, inventor of the abortion pill, dies at 98

ROME -- French scientist Etienne-Emile Baulieu, best known as the inventor of the abortion pill, died on Friday aged 98 at his home in Paris, his institute said in a statement. Both a doctor and a researcher, Baulieu was known around the world for the scientific, medical and social significance of his work on steroid hormones. 'His research was guided by his attachment to the progress made possible by science, his commitment to women's freedom, and his desire to enable everyone to live better, longer lives,' the Institut Baulieu said in the statement posted on its website. Born Etienne Blum in Strasbourg on Dec. 12, 1926, he took the name 'Émile Baulieu' when he joined the French Resistance against the Nazi occupation at the age of 15. An endocrinologist with a doctorate in medicine completed in 1955 and one in science eight years later, in 1963 Baulieu founded a pioneering research unit working on hormones at INSERM, the French institute for health and medical research. He remained as head of the unit until 1997. He is best known for his development, in 1982, of RU 486, the so-called 'abortion pill' that changed the lives of millions of women throughout the world, offering them the possibility of voluntary medical termination of pregnancy, in physical and psychological safety. The Institut Baulieu said it was 'a non-invasive method, less aggressive and less delayed than surgery,' noting that following his discovery the researcher faced fierce criticism and even threats from opponents of women's abortion rights. 'Even today, access to this method is opposed, banned in some countries, and is currently being challenged in the United States, where it is the most widely used abortion method,' the institute added. Baulieu's research into DHEA, a hormone whose secretion and anti-aging activity he had discovered, led him to work on neurosteroids -- or steroids of the nervous system. He also developed an original treatment to combat depression, for which a clinical trial is currently underway in several university hospitals. In 2008, he founded the Institut Baulieu to understand, prevent and treat neurodegenerative diseases such as Alzheimer's. Honored with the grand crosses of the Légion d'honneur (legion of honor) and the Ordre national du Mérite (national order of merit), he was elected to the French Academy of Sciences in 1982, which he chaired in 2003 and 2004. He was a member of the national advisory committee on life sciences and health (1996-2002) and received numerous awards, both in France and abroad. French President Emmanuel Macron paid tribute to Baulieu in a post on X, calling him 'a beacon of courage' and 'a progressive mind who enabled women to win their freedom.' 'Few French people have changed the world to such an extent,' he added. After the death of his first wife, Yolande Compagnon, he remarried, to Simone Harari Baulieu. He is survived by three children, eight grandchildren and nine great-grandchildren, his institute said.

French scientist Etienne-Emile Baulieu, inventor of the abortion pill, dies at 98
French scientist Etienne-Emile Baulieu, inventor of the abortion pill, dies at 98

Yahoo

time6 hours ago

  • Yahoo

French scientist Etienne-Emile Baulieu, inventor of the abortion pill, dies at 98

ROME (AP) — French scientist Etienne-Emile Baulieu, best known as the inventor of the abortion pill, died on Friday aged 98 at his home in Paris, his institute said in a statement. Both a doctor and a researcher, Baulieu was known around the world for the scientific, medical and social significance of his work on steroid hormones. 'His research was guided by his attachment to the progress made possible by science, his commitment to women's freedom, and his desire to enable everyone to live better, longer lives,' the Institut Baulieu said in the statement posted on its website. Born Etienne Blum in Strasbourg on Dec. 12, 1926, he took the name 'Émile Baulieu' when he joined the French Resistance against the Nazi occupation at the age of 15. An endocrinologist with a doctorate in medicine completed in 1955 and one in science eight years later, in 1963 Baulieu founded a pioneering research unit working on hormones at INSERM, the French institute for health and medical research. He remained as head of the unit until 1997. He is best known for his development, in 1982, of RU 486, the so-called 'abortion pill' that changed the lives of millions of women throughout the world, offering them the possibility of voluntary medical termination of pregnancy, in physical and psychological safety. The Institut Baulieu said it was 'a non-invasive method, less aggressive and less delayed than surgery,' noting that following his discovery the researcher faced fierce criticism and even threats from opponents of women's abortion rights. 'Even today, access to this method is opposed, banned in some countries, and is currently being challenged in the United States, where it is the most widely used abortion method,' the institute added. Baulieu's research into DHEA, a hormone whose secretion and anti-aging activity he had discovered, led him to work on neurosteroids -- or steroids of the nervous system. He also developed an original treatment to combat depression, for which a clinical trial is currently underway in several university hospitals. In 2008, he founded the Institut Baulieu to understand, prevent and treat neurodegenerative diseases such as Alzheimer's. Honored with the grand crosses of the Légion d'honneur (legion of honor) and the Ordre national du Mérite (national order of merit), he was elected to the French Academy of Sciences in 1982, which he chaired in 2003 and 2004. He was a member of the national advisory committee on life sciences and health (1996-2002) and received numerous awards, both in France and abroad. French President Emmanuel Macron paid tribute to Baulieu in a post on X, calling him 'a beacon of courage' and 'a progressive mind who enabled women to win their freedom.' 'Few French people have changed the world to such an extent,' he added. After the death of his first wife, Yolande Compagnon, he remarried, to Simone Harari Baulieu. He is survived by three children, eight grandchildren and nine great-grandchildren, his institute said.

DOWNLOAD THE APP

Get Started Now: Download the App

Ready to dive into the world of global news and events? Download our app today from your preferred app store and start exploring.
app-storeplay-store