'Taken aback that it's this far advanced': Medical expert weighs in on Joe Biden's 'most aggressive type' of prostate cancer with bone metastasis
Former President Joe Biden was diagnosed with an "aggressive form" of prostate cancer that has a five-year survival rate of between 30% and 40%.
The former president's prostate cancer is characterized by a Gleason score of 9 and Grade Group 5 with bone metastasis, indicating that it is "pretty far advanced," Fox News senior medical analyst Dr. Marc Siegel said on 'Fox Report.'
"It's the most aggressive type," Siegel said.
"That means it has the highest risk of spread — which obviously he has had."
Biden is also presenting with urinary symptoms, which is another sign that the cancer is advanced.
Prostate cancer often presents as asymptomatic in its early stages, he said.
"This was found by physical examination by a prostate exam," Siegel said.
"A lot of times we find an elevation in prostate-specific antigen, PSA, and then we go after it… I mean, he must have had the best possible care here. I'm a little taken aback that it's this far advanced."
Siegel said he conducts a prostate-specific antigen, or PSA, test on every male over the age of 45 years old. The test measures how much PSA is in the blood and is primarily used to screen for prostate cancer, according to Mayo Clinic.
While the PSA test is not always a perfect indicator of prostate cancer, someone who has a rise in PSA automatically gets an MRI, Siegel said. After the MRI, a decision is made about whether to conduct a biopsy.
More than 80% of men over the age of 80 years old have some prostate cancer cells in their body, according to Siegel.
"It would be really surprising if they weren't doing a very close screening on this because everybody knows in the medical community that this is the one cancer in men you really look out for," he said. "… He doesn't seem to have a lot of risk factors that I would think about other than age, but age is enough and he's 82, so that's a big risk factor."
Doctors will likely treat Biden with hormone therapy, Siegel said.
They may also attempt to radiate the lesion found on the bone or remove the prostate altogether.
"Sometimes they decide to do more than one therapy," Siegel said.
"They might try to take the prostate out, do radiation and the hormone therapy altogether. That's not uncommon."
There are two types of medications used to treat this type of advanced prostate cancer — Lupron, which stops testosterone production, and Casodex, which stops testosterone from binding.
Side effects of the medication can leave people feeling "fatigued and listless", according to Siegel.
"The other thing I'm concerned about is bone pain, because those metastases to the bone can be pretty painful," he said.
If the cancer is caught early while its still localized to the prostate gland, it's curable "most of the time", Siegel said.
"The goal is to get it before it leaves the prostate," Siegel said.
"When it's left the prostate, it becomes much more difficult to cure."
Originally published as 'Taken aback that it's this far advanced': Medical expert weighs in on Joe Biden's 'most aggressive type' of prostate cancer with bone metastasis
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In some ways, she resembles today's self-appointed heroes who reveal their groundbreaking treatment that busts open the orthodoxy. Kenny appears to have been a skilled self-promoter. She became famous in the United States and her story even featured in a 1946 Hollywood movie. But some saw her as a tireless propagandist who manipulated, or even falsified, her results. She claimed to have achieved an astounding 80 per cent recovery rate, but this was based on observation and intuition rather than any scientific study. MORE ASK FUZZY: Her approach was based on a fundamental misconception that the problem was a muscular one that could be corrected through "muscle re-education". As some researchers thought at the time and has subsequently been proven, polio paralysis is actually a neurological condition. As someone with direct experience of RSI (Repetitive Strain Injury) and Frozen Shoulder (adhesive capsulitis), I cannot imagine a worse treatment than to stop a person exercising. Treatment today is more nuanced. As with the Kenny method, it includes hot moist packs and physical therapy. However, institutions such as the Mayo Clinic also include appropriate bed rest and even "splints or other devices to encourage good position of the spine and limbs". The Fuzzy Logic Science Show is at 11am Sundays on 2xx 98.3FM. Send your questions to AskFuzzy@ Podcast: In June 1916, New York officially declared a polio epidemic and, in doing so, instigated a practice that we might find unacceptable today. Newspapers published the names and addresses of sufferers, placards were nailed to doors, and families quarantined. Australians too, were affected. Polio became a notifiable disease in Tasmania and other states by 1922. Despite these measures, polio incidents continued to rise until 1938, when in Australia the number of cases peaked at 39 per 100,000. Polio, sometimes called infantile paralysis, is a devastating disease that causes muscle fatigue and spasms in the limbs, often accompanied by severe pain. When Elizabeth Kenny first encountered the disease, the accepted practice was to immobilise the patient. With splints and plaster body casts to prevent muscle tightening, many paralysed patients lay for months at a time. Unfortunately this would often atrophy both affected and healthy muscles. The Australian Elizabeth Kenny (1880 -1952) became something of a maverick by developing what was then considered a radical treatment. In 1913 Kenny opened a small hospital in Queensland, where her method was reportedly used with success. To ease pain, she lay strips of hot moist cloth over the person's affected areas. And rather than immobilising her patients, she had them do exercises such as bending and flexing joints. Several times a day, they'd move them through a limited range of motion. In doing so, she went directly against the orthodoxy, but her methods are now thought to be a forerunner of modern physiotherapy. However Elizabeth Kenny remains a tricky subject. In some ways, she resembles today's self-appointed heroes who reveal their groundbreaking treatment that busts open the orthodoxy. Kenny appears to have been a skilled self-promoter. She became famous in the United States and her story even featured in a 1946 Hollywood movie. But some saw her as a tireless propagandist who manipulated, or even falsified, her results. She claimed to have achieved an astounding 80 per cent recovery rate, but this was based on observation and intuition rather than any scientific study. MORE ASK FUZZY: Her approach was based on a fundamental misconception that the problem was a muscular one that could be corrected through "muscle re-education". As some researchers thought at the time and has subsequently been proven, polio paralysis is actually a neurological condition. 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