FINANCIAL ADVISORY & RESTRUCTURING EXPERT ANDREW COWIE JOINS PALADIN MANAGEMENT AS MANAGING DIRECTOR
Cowie draws on 25+ years of experience in complex financial matters to help organizations unlock value and navigate critical transitions
NEW YORK, May 29, 2025 /PRNewswire/ -- Paladin Management, a middle-market advisory firm driving value creation through financial, strategic and operational consulting services, is pleased to announce that Andrew Cowie has joined the firm as Managing Director. Based in New York, Cowie will serve Paladin clients globally.
"Andrew brings deep expertise to his role at Paladin, providing senior-level advice, innovative solutions, and tailored strategies to clients navigating complex situations," said Scott Avila, Founder of Paladin. "He also excels at building consensus, aligning stakeholders, and crafting strategic plans that drive value - qualities our clients rely on when facing turnarounds, bankruptcy, and complicated stakeholder dynamics."
Andrew is a seasoned professional with more than 25 years of experience providing in and out-of-court financial restructuring advisory and crisis management services to clients. He has worked across a broad range of industries including entertainment and media, retail and consumer, and infrastructure and energy in providing value added leadership to address complex business challenges.
"The firm's reputation for making smart moves under pressure and staying focused on maximizing outcomes is what drew me to join Scott and the Paladin team," said Andrew Cowie. "Paladin's collaborative, hands-on approach aligns perfectly with my belief in closely partnering with stakeholders, to deliver practical solutions with sustainable results."
Prior to joining Paladin, Cowie held senior positions at Berkeley Research Group (BRG), Capstone Advisory Group, and FTI Consulting, advising clients in a range of distressed situations.
Cowie holds a B.A. in Economics from Western University and an MBA from York University, Schulich School of Business. He is a Certified Public Accountant (CPA), a Certified Insolvency & Restructuring Advisor (CIRA) and a Chartered Financial Analyst (CFA).
About Paladin Management
Founded in 2019, Paladin Management provides a range of middle-market services across restructuring, transaction advisory, performance improvement, strategic communications and strategic advisory. The firm has offices in New York, Chicago, Dallas, Houston and Los Angeles.
For more information on Paladin, visit http://www.paladinmgmt.com/.
Media ContactTisha Kreslerpress@paladinmgmt.com
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PLS PROJECT WINTER DRILLING DELIVERS POSITIVE RESULTS AT SALOON EAST
PERTH, Australia, June 2, 2025 /CNW/ - Paladin Energy Ltd (ASX: PDN) (TSX: PDN) (OTCQX: PALAF) ("Paladin" or the "Company") is pleased to advise it has successfully completed a winter exploration program at the Patterson Lake South (PLS) high-grade uranium project in the Athabasca Basin region of Saskatchewan, Canada. The winter program was carried out in line with the Company's strategic objective to identify additional uranium mineralization outside of the Triple R deposit within the largely underexplored 31,039-hectare PLS project. The results represent the strongest radioactivity identified outside of the Triple R Deposit at PLS. Twenty drillholes totalling 7,102.9m were completed between February and May 2025, with eleven drillholes targeting the Saloon East area, 3.5km southeast of the Triple R deposit (Figure 1 and Table 1). All eleven drillholes at Saloon East intersected highly elevated radioactivity in multiple zones and over significant widths with downhole gamma probe peaks up to 51,303 counts per second (cps). Radioactivity across the Saloon East area has been defined by drilling in two areas separated by 550m (Figure 2), between 200m and 420m vertically from surface within a consistent package of steeply southeast dipping, hydrothermally altered and structurally deformed basement rocks. Drilling Highlights Twenty exploration drillholes between February and May, totalling 7,102.9m Drilling was primarily focused at Saloon East to target elevated radioactivity intersected in 2024 Saloon East – Eleven drillholes completed, encountering highly elevated radioactivity associated with strong hydrothermal alteration, including: PLS25-688A – 41.2m of total composite radioactivity, including 12.3m of continuous radioactivity averaging 3,582 cps with a maximum of 13,657 cps PLS25-693 – 51.0m of total composite radioactivity, including 37.2m of continuous radioactivity averaging 4,761 cps with a maximum of 34,636 cps PLS25-696 – 56.7m of total composite radioactivity, including 11.5m of continuous radioactivity averaging 8,957 cps with a maximum of 51,303 cps PLS25-698 – 25.2m of total composite radioactivity, including 12.5m of continuous radioactivity averaging 4,198 cps with a maximum of 27,730 cps PLG-3 – one reconnaissance drillhole 100m west of the R1515W orebody intersected intensely altered basement rocks with anomalous radioactivity: PLS25-704 – 53.5m of total composite radioactivity, including 32.6m averaging 2,116.7 cps with a maximum of 5,133.3 cps Paladin CEO, Ian Purdy said: "Our Canadian team are very encouraged by the initial results we are seeing at Saloon East. The drilling results at Saloon East represent the strongest radioactivity intersected on the PLS property to date outside of the Triple R deposit. All eleven Saloon East drillholes completed to date in 2025 intersected radioactivity and have provided exciting results over significant core lengths. The widespread presence of elevated radioactivity and hydrothermal alteration suggests that we are exploring a significant mineralised system." Overview of the Saloon Trend The Saloon Trend is a linear, multi-kilometre long, southwest-northeast trending structural zone up to 1km in width, that is parallel to and located 3.5km south of the shear zones that host the Triple R deposit within the Patterson Lake Conductive Corridor. The Saloon Trend has been a major focus of the 2024 and 2025 exploration drilling, with 27 drillholes completed along 8.8km of its strike length. Drilling in August 2024 in the eastern portion of the Saloon Trend intersected anomalous radioactivity in three drillholes, PLS24-680, 682 and 684B, in what was subsequently termed Saloon East. Drilling in the first half of 2025 followed up on the August 2024 results at Saloon East and intersected highly elevated radioactivity, with notable intercepts in drillholes PLS25-696 and 698. Drilling along trend to the northeast intersected a thick zone of elevated radioactivity in PLS25-693, leaving a highly prospective 550m long untested zone between the two established zones of radioactivity. Figure 1: 2025 Regional Drillhole Plan Map Figure 2: Saloon East drilling to date Table 1: 2025 Regional Exploration Drill Hole Summary Collar Basement depth (m) Totaldepth (m) 2PGA-1000 Gamma probe (≥500 cps / ≥0.5 m minimum) ExplorationArea Hole ID Easting(UTM NAD83) Northing(UTMNAD83) Elevation(masl) Azimuth(deg) Dip(deg) From To Interval Average cps Max cps Saloon East PLS25-685 601774.8 6388784.0 498.3 128 -70 44.4 558.0 263.6 272.1 8.5 694 2,009 279.2 289.2 10.0 2,576 14,772 291.7 294.0 2.3 1,140 2,916 299.7 303.2 3.5 641 1,715 319.1 324.5 5.4 1,177 3,346 333.4 333.9 0.5 578 672 342.9 343.7 0.8 1,406 2,422 387.8 390.5 2.7 2,641 7,413 394.2 396.7 2.5 2,566 10,010 428.5 429.1 0.6 3,713 6,165 PLS25-688A 601789.1 6388769.2 498.0 129 -71 51.0 552.0 108.7 109.8 1.1 589 800 204.6 205.1 0.5 598 687 210.2 215.4 5.2 1,115 3,962 223.1 223.8 0.7 576 637 225.8 236.1 10.3 2,474 11,660 289.7 290.8 1.1 1,377 2,152 312.0 312.5 0.5 1,402 2,002 365.4 365.9 0.5 1,151 1,665 370.4 371.7 1.3 6,133 14,862 416.3 419.8 3.5 4,030 11,964 424.0 426.5 2.5 3,443 11,280 433.2 445.5 12.3 3,582 13,657 497.0 498.7 1.7 773 1,046 PLS25-690 602270.6 6389053.9 498.2 321 -75 51.0 387.0 243.0 246.0 3.0 533 1,092 283.6 290.3 6.7 764 2,122 295.8 297.5 1.7 1,403 2,250 PLS25-691 601800.2 6388759.9 498.2 129 -71 50.6 492.1 180.9 184.3 3.4 682 919 227.3 227.9 0.6 778 961 251.4 254.7 3.3 531 802 268.1 272.0 3.9 960 1,951 418.3 424.8 6.5 627 1,847 427.8 431.2 3.4 1,057 2,625 443.0 443.8 0.8 536 647 PLS25-692 602270.4 6389065.4 498.0 305 -73 53.5 330.0 190.8 192.0 1.2 669 793 195.6 199.1 3.5 639 2,849 202.7 212.4 9.7 1,314 5,423 234.0 234.8 0.8 612 803 249.7 252.3 2.6 623 944 256.8 267.5 10.7 1,172 4,988 273.5 277.9 4.4 1,650 4,837 317.0 317.6 0.6 1,360 2,015 PLS25-693 602270.4 6389065.4 498.0 310 -68 60.8 318.0 164.8 166.4 1.6 515 726 180.1 181.1 1.0 782 1,271 204.1 210.1 6.0 923 3,976 213.4 217.9 4.5 634 1,908 220.5 257.7 37.2 4,761 34,636 294.4 295.1 0.7 809 1,373 PLS25-694A 601841.6 6388784.0 498.0 129 -75 46.8 348.0 185.7 190.1 4.4 1,418 3,856 195.9 196.4 0.5 867 1,208 198.5 205.5 7.0 1,548 3,010 222.0 223.3 1.3 831 1,190 226.7 228.1 1.4 1,209 1,752 241.6 246.5 4.9 1,079 1,913 250.5 251.2 0.7 824 1,179 264.0 273.7 9.7 928 2,466 288.4 294.1 5.7 871 1,783 PLS25-695 602270.4 6389065.4 498.0 305 -60 56.4 213.0 Drillhole lost, not gamma probed PLS25-696 601895.9 6388750.8 498.3 335 -80 64.9 351.0 161.5 164.8 3.3 652 1,185 185.3 218.3 33.0 1,101 6,723 222.9 224.3 1.4 703 896 227.6 232.3 4.7 738 2,057 241.9 253.4 11.5 8,957 51,303 258.8 260.9 2.1 1,750 4,473 306.5 307.2 0.7 662 943 PLS25-697 602252.2 6389079.1 498.2 304 -66.25 74.4 250.1 120.5 125.8 5.3 563 1,099 138.6 139.5 0.9 604 798 141.0 141.5 0.5 675 793 152.4 161.5 9.1 611 1,960 172.7 173.6 0.9 618 677 177.1 178.1 1.0 608 679 184.2 188.8 4.6 1,377 4,104 193.9 195.7 1.8 925 1,446 PLS25-698 602019.0 6388634.2 510.7 316 -49 92.5 357.0 134.9 135.5 0.6 717 763 259.2 265.7 6.5 1,513 4,702 276.2 281.8 5.6 954 2,999 291.6 304.1 12.5 4,198 27,730 Saloon PLS25-700A 602083.8 6388022.1 527.1 313 -77 83.6 537.0 183.8 187.9 4.1 554 1,258 436.6 437.3 0.7 806 1,107 446.7 447.3 0.6 947 1,232 PLS25-703 598710.0 6386314.0 565.0 320 -75 126.0 198.3 Drillhole lost South Patterson PLS25-686A 599131.0 6388680.0 498.1 0 -90 51.0 201.0 129.0 131.0 2.0 624 1,038 134.5 135.5 1.0 568 721 142.7 147.3 4.6 536 821 149.3 152.1 2.8 589 1,145 163.9 164.6 0.7 545 643 174.3 179.1 4.8 692 1,041 181.3 182.8 1.5 666 848 Far East PLS25-687 600112.8 6390497.2 498.3 348 -70 47.8 204.4 No anomalous radioactivity PLS25-689 600359.3 6390575.5 501.9 158 -79 54.2 372.0 No anomalous radioactivity PLG Main PLS25-699 597359.7 6389781.8 536.4 157 -77 95.7 558.0 120.9 124.1 3.2 633 856 128.5 130.5 2.0 501 581 132.6 134.8 2.2 778 1,196 PLS25-701 596345.0 6389136.0 548.3 347 -77 111.0 270.0 104.4 124.5 20.1 1,796 4,076 PLS25-702 596058.2 6389209.5 554.4 155 -60 143.4 288.0 No anomalous radioactivity PLS25-704 596189.5 6389089.4 552.1 335 -78 110.3 318.0 105.0 137.6 32.6 2,117 5,133 138.3 141.2 2.9 634 866 142.8 152.4 9.6 1,036 6,415 170.8 171.4 0.6 795 980 173.0 174.8 1.8 828 1,476 177.8 183.8 6.0 589 1,505 Competent Person's Statement / Qualified Person and Technical Information The drilling and exploration results contained in this document have been prepared in accordance with National Instrument 43-101 Standards of Disclosure for Mineral Projects ("NI 43-101"). The information in this document as it relates to drilling and exploration results was provided by Kanan Sarioglu, a Competent Person and "qualified person" under NI 43-101, who is a registered Professional Geoscientist ( with the Engineers and Geoscientists of British Columbia (EGBC), the Association of Professional Geoscientists and Engineers of Alberta (APEGA) and the Association of Professional Geoscientists and Engineers of Saskatchewan (APEGS). Kanan Sarioglu is the VP Exploration for Paladin Canada and has sufficient experience which is relevant to the style of mineralisation and type of deposit under consideration and to the activity which he is undertaking, to qualify as a Competent Person as defined in the 2012 Edition of the 'Australasian Code for Reporting of Exploration Results, Mineral Resources and Ore Reserves'. Mr. Sarioglu consents to the inclusion in this document of the matters based on the information in the form and context in which it appears. The drilling and exploration results including verification of the data disclosed, has been completed by Kanan Sarioglu following NI 43-101. Mr. Sarioglu has reviewed and approved the contents of this news release. The design of the drilling programs and interpretation of results is under the control of Paladin Canada's geological staff, including qualified persons employing strict protocols consistent with NI 43-101 and industry best practices. Natural gamma radiation that is reported in this news release was measured in counts per second every 10cm throughout the length of each drillhole, in the up and down direction, using a Mount Sopris 2PGA-1000 single gamma probe. Results presented were derived from the up-hole data only. Prior to drilling, the accuracy of the 2PGA-1000 gamma probe was confirmed using a historical calibration drillhole on the PLS property. The reader is cautioned that gamma probe readings are not directly or uniformly related to uranium grades of the rock sample measured and should be used only as a preliminary indication of the presence of radioactive materials. All intersections are down-hole depths. All depths reported of core interval measurements including radioactivity and mineralization intervals widths are not always representative of true thickness. Forward-looking statements This announcement includes forward-looking information (forward-looking statements) that can generally be identified by words such as "anticipate", "expect", "likely", "propose", will", "intend", "should", "could", "may", "believe", "forecast", "estimate", "target", "outlook", "guidance" and similar expressions. Forward-looking statements involve subjective judgment and are subject to significant uncertainties and contingencies (including risk factors associated with the mining industry), many of which are outside the control of the Company. Although at the date of this announcement Paladin believes the forward-looking statements contained herein are based on reasonable assumptions, such statements are not guarantees of future performance. Actual results or developments may differ materially from the Company's expectations due to a range of factors including fluctuations in commodity prices and exchange rates, exploitation and exploration successes, permitting and development issues, political risks, First Nation engagement, climate risk, natural disasters, regulatory concerns, continued availability of capital and financing, general economic and market conditions, general uranium industry factors, and other factors. The Company makes no representation, warranty, guarantee or assurance (express or implied) that any forward-looking statements will prove to be correct. Except for statutory liability, which cannot be excluded, the Company, its officers, employees and advisers expressly disclaim any responsibility for the accuracy or completeness of the material contained in this announcement and exclude all liability whatsoever (including in negligence) for any loss or damage which may be suffered by any person as a consequence of any information in this announcement or any error or omission therefrom. The Company accepts no responsibility to update any person regarding any inaccuracy, omission or change in information in this announcement or any other information made available to a person nor any obligation to furnish the person with any further information. JORC Code, 2012 Edition – Table 1 Section 1 Sampling Techniques and Data (Criteria in this section apply to all succeeding sections.) Criteria JORC Code explanation Commentary Sampling techniques Nature and quality of sampling (eg cut channels, random chips, or specific specialised industry standard measurement tools appropriate to the minerals under investigation, such as down hole gamma sondes, or handheld XRF instruments, etc). These examples should not be taken as limiting the broad meaning of sampling. Include reference to measures taken to ensure sample representivity and the appropriate calibration of any measurement tools or systems used. Aspects of the determination of mineralisation that are Material to the Public Report. In cases where 'industry standard' work has been done this would be relatively simple (eg 'reverse circulation drilling was used to obtain 1 m samples from which 3 kg was pulverised to produce a 30 g charge for fire assay'). In other cases more explanation may be required, such as where there is coarse gold that has inherent sampling problems. Unusual commodities or mineralisation types (eg submarine nodules) may warrant disclosure of detailed information. Results reported in this announcement consist of downhole radioactivity measured using a 2PGA-1000 gamma probe The 2PGA-1000 gamma probe records radioactivity in counts per second (cps) every 10 cm throughout the entire length of the drillhole in both the up and down directions, at a speed of approximately 6 m/minute Gamma probe measurements are made within the drill rods The 2PGA-1000 gamma probe comes calibrated from the manufacturer and is checked on site at Patterson Lake South using a historical calibration drillhole Drilling techniques Drill type (eg core, reverse circulation, open-hole hammer, rotary air blast, auger, Bangka, sonic, etc) and details (eg core diameter, triple or standard tube, depth of diamond tails, face-sampling bit or other type, whether core is oriented and if so, by what method, etc). All drilling reported in this release was completed using a Zinex A5 core drill In select drillholes with poor ground conditions at the top of bedrock HQ (63.5 mm) diameter coring was performed, but drillholes are primarily NQ (47.6 mm) diameter, standard tube Drill core is orientated by the logging geologist, with orientation marks provided by a REFLEX ACTIII Drill sample recovery Method of recording and assessing core and chip sample recoveries and results assessed. Measures taken to maximise sample recovery and ensure representative nature of the samples. Whether a relationship exists between sample recovery and grade and whether sample bias may have occurred due to preferential loss/gain of fine/coarse material. Drill core recovery is not relevant to this release as it pertains to in-situ gamma probe results Logging Whether core and chip samples have been geologically and geotechnically logged to a level of detail to support appropriate Mineral Resource estimation, mining studies and metallurgical studies. Whether logging is qualitative or quantitative in nature. Core (or costean, channel, etc) photography. The total length and percentage of the relevant intersections logged. All core drilled at the PLS project has been geologically and geotechnically logged in detail Drill core relevant to this news release has not been logged in a level of detail to support resource estimation or mining studies as these are exploration drillholes Logging is qualitative in nature core photos have been collected for all drill core Sub-sampling techniques and sample preparation If core, whether cut or sawn and whether quarter, half or all core taken. If non-core, whether riffled, tube sampled, rotary split, etc and whether sampled wet or dry. For all sample types, the nature, quality and appropriateness of the sample preparation technique. Quality control procedures adopted for all sub-sampling stages to maximise representivity of samples. Measures taken to ensure that the sampling is representative of the in situ material collected, including for instance results for field duplicate/second-half sampling. Whether sample sizes are appropriate to the grain size of the material being sampled. Not relevant to this release Quality of assay data and laboratory tests The nature, quality and appropriateness of the assaying and laboratory procedures used and whether the technique is considered partial or total. For geophysical tools, spectrometers, handheld XRF instruments, etc, the parameters used in determining the analysis including instrument make and model, reading times, calibrations factors applied and their derivation, etc. Nature of quality control procedures adopted (eg standards, blanks, duplicates, external laboratory checks) and whether acceptable levels of accuracy (ie lack of bias) and precision have been established. Radioactivity measurements in this release were recorded using a 2PGA-1000 single gamma probe manufactured by Mount Sopris The gamma probe comes calibrated from the manufacturer, and Paladin has an on-site check drillhole which is used to confirm the probe accuracy prior to the start of every drill campaign Radioactivity measurements were recorded every 10 cm Drillholes are surveyed in the down and up directions, effectively duplicating the results, which are compared for any discrepancies after surveying Verification of sampling and assaying The verification of significant intersections by either independent or alternative company personnel. The use of twinned holes. Documentation of primary data, data entry procedures, data verification, data storage (physical and electronic) protocols. Discuss any adjustment to assay data. Significant intersections have not been verified by independent or alterative company personnel No holes have been twinned Gamma probe data was collected at the drill by Paladin contactors, then the raw data was directly issued to the Paladin technical team All probe data is converted to Excel format and stored in Paladin's drillhole database Location of data points Accuracy and quality of surveys used to locate drill holes (collar and down-hole surveys), trenches, mine workings and other locations used in Mineral Resource estimation. Specification of the grid system used. Quality and adequacy of topographic control. All drillhole collars are positioned using a Trimble real time kinematic GPS system All coordinates are in UTM NAD83 Drillholes are aligned to the planned azimuth and dip using a TN-14 azimuth aligner A final collar position is collected using the Trimble GPS once the drill has moved off the site Drillhole azimuth and dip information is measured every 50 m during drilling using a REFLEX EZ-Trac The PLS property has a detailed digital terrane model to provide topographic control Data spacing and distribution Data spacing for reporting of Exploration Results. Whether the data spacing and distribution is sufficient to establish the degree of geological and grade continuity appropriate for the Mineral Resource and Ore Reserve estimation procedure(s) and classifications applied. Whether sample compositing has been applied. Pierce point spacing for exploration drilling can vary between 15 to 50 m depending on the geology and level of radioactivity encountered Drillhole pierce point spacing is considered appropriate for the current exploration stage of drillholes in this release Orientation of data in relation to geological structure Whether the orientation of sampling achieves unbiased sampling of possible structures and the extent to which this is known, considering the deposit type. If the relationship between the drilling orientation and the orientation of key mineralised structures is considered to have introduced a sampling bias, this should be assessed and reported if material. Drilling orientations are generally sub-perpendicular to the interpreted dip of the geology, but there is limited knowledge of the geology in exploration areas Occasional drillholes will be orientated parallel to features of interest to test their depth extent It is noted within the release that all radioactive intervals are core lengths and not true widths Sample security The measures taken to ensure sample security. Not relevant to this release Audits or reviews The results of any audits or reviews of sampling techniques and data. No audits or reviews of the data presented in this release have occurred Section 2 Reporting of Exploration Results (Criteria listed in the preceding section also apply to this section.) Criteria JORC Code explanation Commentary Mineral tenement and land tenure status Type, reference name/number, location and ownership including agreements or material issues with third parties such as joint ventures, partnerships, overriding royalties, native title interests, historical sites, wilderness or national park and environmental settings. The security of the tenure held at the time of reporting along with any known impediments to obtaining a licence to operate in the area. Drilling presented in this release was completed on mineral claim S-111376 which is 100% owned by Fission Uranium Corp a subsidiary of Paladin Energy Ltd. All claims are in good standing and all necessary permits for drilling and geophysical surveys have been received Exploration done by other parties Acknowledgment and appraisal of exploration by other parties. The PLS project has been explored by a number of historical exploration companies including Uranerz Exploration and Mining Ltd., Hudson Bay Exploration and Development and Canadian Occidental Petroleum Ltd. There are historical drillholes on the property, none of which have tested the areas presented in this announcement Geology Deposit type, geological setting and style of mineralisation. The target deposit type is unconformity-associated high-grade uranium, hosted at the base of the Athabasca Basin or underlying metamorphic basement rocks Drill hole Information A summary of all information material to the understanding of the exploration results including a tabulation of the following information for all Material drill holes: easting and northing of the drill hole collar elevation or RL (Reduced Level – elevation above sea level in metres) of the drill hole collar dip and azimuth of the hole down hole length and interception depth hole length. If the exclusion of this information is justified on the basis that the information is not Material and this exclusion does not detract from the understanding of the report, the Competent Person should clearly explain why this is the case. This information is included in Table 1 of the announcement No material information has been excluded Data aggregation methods In reporting Exploration Results, weighting averaging techniques, maximum and/or minimum grade truncations (eg cutting of high grades) and cut-off grades are usually Material and should be stated. Where aggregate intercepts incorporate short lengths of high grade results and longer lengths of low grade results, the procedure used for such aggregation should be stated and some typical examples of such aggregations should be shown in detail. The assumptions used for any reporting of metal equivalent values should be clearly stated. Radioactivity measurements are recorded every 10 cm throughout the drillhole length, no weighting is applied Relationship between mineralisation widths and intercept lengths These relationships are particularly important in the reporting of Exploration Results. If the geometry of the mineralisation with respect to the drill hole angle is known, its nature should be reported. If it is not known and only the down hole lengths are reported, there should be a clear statement to this effect (eg 'down hole length, true width not known'). All intervals are down hole lengths Due to the early-stage nature of these results, true widths are not known at this time Diagrams Appropriate maps and sections (with scales) and tabulations of intercepts should be included for any significant discovery being reported These should include, but not be limited to a plan view of drill hole collar locations and appropriate sectional views. Refer to the figures in the announcement Balanced reporting Where comprehensive reporting of all Exploration Results is not practicable, representative reporting of both low and high grades and/or widths should be practiced to avoid misleading reporting of Exploration Results. All relevant exploration data has been reported Other substantive exploration data Other exploration data, if meaningful and material, should be reported including (but not limited to): geological observations; geophysical survey results; geochemical survey results; bulk samples – size and method of treatment; metallurgical test results; bulk density, groundwater, geotechnical and rock characteristics; potential deleterious or contaminating substances. All relevant exploration data has been reported Further work The nature and scale of planned further work (eg tests for lateral extensions or depth extensions or large-scale step-out drilling). Diagrams clearly highlighting the areas of possible extensions, including the main geological interpretations and future drilling areas, provided this information is not commercially sensitive. Next steps are outlined within the release SOURCE Paladin Energy Ltd View original content to download multimedia: Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
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CARsgen Presents Research Results on Satri-cel in The Lancet and at the 2025 ASCO Annual Meeting
SHANGHAI, June 1, 2025 /PRNewswire/ -- CARsgen Therapeutics Holdings Limited (Stock Code: a company focused on developing innovative CAR T-cell therapies, announces that the results of the pivotal Phase II clinical trial in China (CT041-ST-01, NCT04581473) investigating satricabtagene autoleucel ("satri-cel", CT041) (a Claudin18.2-specific autologous CAR T-cell product candidate) in patients with Claudin18.2-positive, advanced gastric/gastroesophageal junction cancer refractory to at least two prior lines of treatment, have been published in The Lancet and were orally presented at the 2025 ASCO Annual Meeting. Further details have been posted on the corporate website The article in The Lancet was titled "Claudin-18 isoform 2-specific CAR T-cell therapy (satri-cel) versus treatment of physician's choice for previously treated advanced gastric or gastro-oesophageal junction cancer (CT041-ST-01): a randomised, open-label, phase 2 trial". Full article available at: The oral presentation at the 2025 ASCO Annual Meeting (Abstract 4003) was titled "Claudin18.2-specific CAR T cells (Satri-cel) versus treatment of physician's choice (TPC) for previously treated advanced gastric or gastroesophageal junction cancer (G/GEJC): Primary results from a randomized, open-label, phase II trial (CT041-ST-01)". Professor Lin Shen from Beijing Cancer Hospital, the principal investigator of this study, said, "The CT041-ST-01 trial represents the world's first randomized controlled clinical study of CAR-T cell therapy for solid tumors. In patients with heavily pretreated, advanced gastric/gastroesophageal junction cancer who have extremely limited treatment options and poor prognosis, satri-cel has demonstrated breakthrough efficacy with significant clinical benefits, including much improved progression-free survival (PFS), overall survival (OS), and tumor response rates. This brings new hope to patients with otherwise medically untreatable conditions. We are further exploring satri-cel's potential in adjuvant settings and as first-line sequential therapies, aiming to intervene earlier in the disease course, extend patients' survival, and ultimately pursue potential cures." Dr. Zonghai Li, Founder, Chairman of the Board, Chief Executive Officer, and Chief Scientific Officer of CARsgen Therapeutics, said, "We are honored that the CT041-ST-01 study results were published in The Lancet—a premier, global medical journal—and presented at the 2025 ASCO Annual Meeting. The positive result of this randomized controlled trial marks a major milestone in solid tumor CAR-T therapy. These achievements are a testament to the whole research team's years of dedication, and we extend our deepest gratitude to patients and their families for their trust and participation. This year, satri-cel has been granted Breakthrough Therapy Designation and Priority Review by the Center for Drug Evaluation (CDE) of China's National Medical Products Administration (NMPA) for the treatment of Claudin18.2-positive advanced gastric/gastroesophageal junction adenocarcinoma (G/GEJA) in patients who have failed at least two prior lines of therapy. We plan to submit a New Drug Application (NDA) for satri-cel to the NMPA this month and anticipate its approval as the world's first commercially available CAR-T product for solid tumors, bringing benefits to patients." About Satri-cel Satri-cel is an autologous CAR T-cell product candidate against the protein Claudin18.2 that has the potential to be the first-in-class globally. Satri-cel targets the treatment of Claudin18.2-positive solid tumors with a primary focus on G/GEJA and pancreatic cancer (PC). Initiated trials include investigator-initiated trials (CT041-CG4006, NCT03874897), a confirmatory Phase II clinical trial for advanced G/GEJA in China (CT041-ST-01, NCT04581473), a Phase Ib clinical trial for PC adjuvant therapy in China (CT041-ST-05, NCT05911217), an investigator-initiated trial for satri-cel be used as consolidation treatment following adjuvant therapy in patients with resected G/GEJA (CT041-CG4010, NCT06857786), and a Phase 1b/2 clinical trial for advanced gastric or pancreatic adenocarcinoma in North America (CT041-ST-02, NCT04404595). Satri-cel has been granted Priority Review by the Center for Drug Evaluation (CDE) of China's National Medical Products Administration (NMPA) for the treatment of Claudin18.2-positive advanced G/GEJA in patients who have failed at least two prior lines of therapy in May 2025. Satri-cel has been granted Breakthrough Therapy Designation by the CDE of China's NMPA for the treatment of Claudin18.2-positive advanced G/GEJA in patients who have failed at least two prior lines of therapy in March 2025. Satri-cel was granted Regenerative Medicine Advanced Therapy designation by U.S. FDA for the treatment of advanced G/GEJA with Claudin18.2-positive tumors in January 2022. Satri-cel received Orphan Drug designation from the U.S. FDA in September 2020 for the treatment of G/GEJA. About CARsgen Therapeutics Holdings Limited CARsgen is a biopharmaceutical company focusing on developing innovative CAR T-cell therapies to address the unmet clinical needs including but not limited to hematologic malignancies, solid tumors and autoimmune diseases. CARsgen has established end-to-end capabilities for CAR T-cell research and development covering target discovery, preclinical research, product clinical development, and commercial-scale production. CARsgen has developed novel in-house technologies and a product pipeline with global rights to address challenges faced by existing CAR T-cell therapies. Efforts include improving safety profile, enhancing the efficacy in treating solid tumors, and reducing treatment costs, etc. CARsgen's mission is to be a global biopharmaceutical leader that provides innovative and differentiated cell therapies for patients worldwide and makes cancer and other diseases curable. Forward-looking Statements All statements in this press release that are not historical fact or that do not relate to present facts or current conditions are forward-looking statements. Such forward-looking statements express the Group's current views, projections, beliefs and expectations with respect to future events as of the date of this press release. Such forward-looking statements are based on a number of assumptions and factors beyond the Group's control. As a result, they are subject to significant risks and uncertainties, and actual events or results may differ materially from these forward-looking statements and the forward-looking events discussed in this press release might not occur. Such risks and uncertainties include, but are not limited to, those detailed under the heading "Principal Risks and Uncertainties" in our most recent annual report and interim report and other announcements and reports made available on our corporate website, No representation or warranty is given as to the achievement or reasonableness of, and no reliance should be placed on, any projections, targets, estimates or forecasts contained in this press release. Contact CARsgen For more information, please visit View original content to download multimedia: SOURCE CARsgen Therapeutics
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HORIZON PETROLEUM PROVIDES AN OPERATIONS UPDATE OF ITS PREPARATION FOR FIRST PRODUCTION IN POLAND
CALGARY, AB, June 1, 2025 /PRNewswire/ - Horizon Petroleum Ltd. (the "Company" or "Horizon") (TSXV: HPL) (FRA: HPM) (Tradegate: HPM) is pleased to provide an operations update on progress made towards first production from its cornerstone Lachowice gas development in the Bielsko-Biala concession, southern Poland. David Winter, CEO of the Horizon commented: " We are pleased with the continuing progress in our operations towards first production from the Lachowice 7 well. Board and Management recognise the efforts of our operating team in Poland in ensuring that the initial development program is executed as planned. We also recognise the very positive relationships that we enjoy with our neighbours at Lachowice, and the positive contributions from our contractors, local authorities and government. We look forward to our continuing work with all stakeholders and will update shareholders as the initial development program progresses". Assuming a successful workover result, gas and/or electrical power sales from the Lachowice 7 (L7) well will provide the Company with its first cashflow and will provide a long-term test of the production performance of the naturally fractured, Devonian aged, limestone and dolomite reservoirs in the L7 well. Preparatory work for the L7 workover is progressing on schedule: The Environmental Impact Assessment (EIA) Permit for the L7 workover has been approved by the Ministry of Climate and the Environment (the "Ministry"). With the funds from the recent successful debenture financing, long lead time materials and services have been sourced and ordered with expected deliveries in August and September. These materials include the tubing, wellhead and completion equipment. The Company has received confirmation from its electrical contractor that the local utility company will move the power line that crosses the L7 wellsite by the end of June. Final civil engineering design for the wellsite and access road has been completed and tendering for the construction works to be awarded in the next 3-4 weeks. Wellsite and access road construction to commence in July once the above-mentioned electricity line has been moved. The Company is working with a local service provider to choose the appropriate rig for the workover, now scheduled to commence in September with long-term production testing of the well in October. Early Production System (EPF) The Company continues the work towards finalizing the early production scheme for the initial development at the L7 well following the workover and testing. As previously disclosed, the Company contracted a local electrical engineering company and a mechanical engineering company to review options to monetize gas production from the initial development at L7 and the full field development Lachowice gas field. The reviews and investigations are largely completed: Gas to Power: The company has identified two access points into the local electricity transmission grids. The first with 2MW capacity is located with 300m of the L7 wellsite. The second with 4MW capacity is located approximately 1km from the L7 wellsite. Horizon has made an application to secure the 2MW capacity that will be the first tie-in point for G2P. The company continues to work towards securing the 4MW at the second location. The preliminary design of the gas processing facility that will be required to separate the liquid condensate and any free water from the L7 gas stream has been completed. The Company has commenced sourcing the required vessels and other process equipment. Work on the EIA for the production facility is underway targeting submission in mid-June. Full Field Development Plan The Company has commenced the preliminary work for the EIA for the planned 100km2 3D seismic survey over the Lachowice gas field. A third-party evaluation has identified a high-pressure gas network tie-in point approximately 14 km northeast of L7, half the distance of the previous plan, which will result in reduced pipeline costs and faster approvals. Takeaway capacities have been confirmed and are consistent with Horizon's short and long-term forecast production volumes. The Company has commenced discussions with pipeline operator and owner to secure access and pipeline capacity. The Company will shortly commence the initial work on the EIA for the full field development facility site and commence the process to rezone the land for industrial use. Lachowice 7 Well Workover Operations Program The L7 workover is scheduled to be conducted in September/October of this year subject to receiving the necessary long lead items, equipment and services as planned. A detailed program has been completed and application to the Polish Mining authority for the program will be submitted shortly. The workover program will consist of: Upgrade the wellhead to execute the workover and eventual production. Drill out a surface cement plug and downhole mechanical plug in the wellbore. Pressure test the existing well casing to ensure wellbore security and integrity Drill and recover an existing packer located above the zone that originally tested up to 8.9mmscf/d gas Reperforate, acid stimulation and production test of this same zone Complete the well for production in anticipation of the EPF to be installed on site in first half 2026. The Company is targeting gas/electricity sales and first cash flow by the first half of 2026. About Horizon Petroleum Ltd. Calgary-based Horizon is focused on the appraisal and development of natural gas and oil reserves in Europe. The Management and Board of Horizon consist of oil & gas professionals with significant international experience. Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release. This press release contains "forward-looking statements" or "forward-looking information" (collectively referred to herein as "forward-looking statements") within the meaning of applicable securities legislation. Such forward-looking statements include, without limitation, forecasts, estimates, expectations and objectives for future operations that are subject to a number of assumptions, risks and uncertainties, many of which are beyond the control of Horizon. Forward-looking statements are statements that are not historical facts and are generally, but not always, identified by the words "expects", "plans", "anticipates", "believes", "intends", "estimates", "projects", "potential" and similar expressions, or that events or conditions "will", "would", "may", "could" or "should" occur or be achieved. This press release contains forward-looking statements pertaining to, among other things the timing of re-entry of the well, the moving of the infrastructure in the area, timing of sales gas, and other operational matters in this news release, all of which are subject to change. Forward-looking information is based on current expectations, estimates and projections that involve a number of risks, which could cause actual results to vary and in some instances to differ materially from those anticipated by Horizon and described in the forward-looking information contained in this press release. Although Horizon believes that the material factors, expectations and assumptions expressed in such forward-looking statements are reasonable based on information available to it on the date such statements were made, no assurances can be given as to future results, levels of activity and achievements and such statements are not guarantees of future performance. View original content to download multimedia: SOURCE Horizon Petroleum Ltd. Sign in to access your portfolio
