
SlimFast on the block as dieters turn to jabs
SlimFast has been put up for sale as dieters increasingly shun meal replacements in favour of weight-loss jabs.
Glanbia, the brand's owner, is looking to offload SlimFast after a recent drop in sales – prompted by heightened demand for blockbuster drugs such as Wegovy.
Mark Garvey, the chief financial officer of Glanbia, said: 'We've decided to move on because we believe there is a significant change in how weight management is being managed by our consumers.'
Founded in Florida in 1977, SlimFast's low-calorie meal replacements soared to prominence in the 1980s and 1990s as diet culture gripped the US and UK – turning it into one of the world's best-known weight-loss brands.
However, in recent years sales have fallen as dieters swapped traditional meal replacements and dieting for new drugs.
In 2023, SlimFast lost 33pc of its sales in three months as the jabs exploded in popularity.
Sold under brands like Wegovy and Mounjaro, weight loss jabs slow the emptying of users' stomachs following meals, making them feel fuller for longer.
Ozempic, arguably the best known, is designed to treat people with type 2 diabetes but is commonly used off-prescription for weight loss.
Around 12pc of American adults were reported to have tried weight loss drugs last year, according to a KFF Health Tracker survey.
Around 500,000 people have also taken them in the UK, according to Simple Online Pharmacy.
This includes high-profile figures such as Boris Johnson, who admitted to using weight-loss jabs two years ago.
As well as traditional weight-loss companies, other large food and drink businesses are also seeing an impact from the jabs – with the chief executive of Walmart previously blaming them for shoppers buying fewer items.
Terry Smith, the British fund manager, ditched his entire stake in Guinness-owner Diageo last year because of fears over the impact of the drugs – which have been shown to reduce alcohol as well as food cravings.
Morgan Stanley has estimated that the global market for obesity drugs could reach as much as $105bn (£83bn) by 2030. The Wall Street bank predicts this will trigger a 3pc fall in Americans' consumption of soft drinks, bakery products and snacks by 2035.
As well as announcing the proposed sale, Glanbia also told investors on Wednesday it had written $91.4m off the value of SlimFast in the Americas because of 'continuing challenges in the weight management category'.
Headquartered in Kilkenny, Ireland, Glanbia sells a range of food supplements and ingredients.
Shares in the company fell by more than 14pc on Wednesday, hitting their lowest point since 2007 as it posted revenues below analysts' estimates and warned over the rising cost of whey.
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Telegraph
an hour ago
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Weight-loss jabs can stop HRT working, doctors warn
Weight-loss drugs could stop hormone replacement therapy from working and increase the associated risks, guidance has warned. The British Menopause Society has told doctors to closely monitor any women who are on hormone replacement therapy (HRT) for the menopause and are also taking a weight-loss jab. The injections, such as Mounjaro and Wegovy, also sold as Ozempic for diabetes, have revolutionised obesity treatment and are increasingly taken by people who are not obese but looking to lose a few pounds. But the drug's ability to delay the transit of food through the gut can slow the absorption of pills taken orally. It is one theory behind the so-called ' Ozempic baby boom '. Earlier this week, the medicines regulator issued a warning about the impact of weight-loss drugs on contraception after receiving more than 40 reports relating to pregnancies from women on the jabs. The Medicines and Healthcare products Regulatory Agency said women should 'not rely on oral contraception' and warned them not to use the injections if pregnant or trying to get pregnant because of a lack of safety evidence. Guidance has now suggested women taking HRT orally may also be at risk. There were 2.6 million women taking HRT in 2023-24 in England to help with symptoms of the menopause, which can include hot flushes, night sweats, difficulty sleeping, mood changes, and muscle aches. It typically onsets between age 45 and 55 and can last for a number of years. The most common form of HRT is a progesterone pill alongside a skin patch or gel to deliver oestrogen, although some women will be on a combined pill. The progesterone is important to balance out the effects of oestrogen, which on its own stimulates the growth of the womb lining, and can cause ' abnormal cells and cancer ' to grow. The loss of the protective effect of progesterone on the womb was the primary concern for the British Menopause Society, which recommended doctors move women to an intrauterine device, such as a Mirena coil, or increase the dose of progesterone. Prof Annice Mukherjee, a consultant endocrinologist and member of the society's medical advisory council, who led on the guidance, said an imbalance in the hormones, particularly among women with obesity, would put them 'at increased risk of womb cancer '. 'Oestrogen is almost always given through the skin for HRT in women living with obesity, but progesterone is frequently given as a tablet, and that formulation is thought to be the safest route for women who have complicated health issues,' she said. 'If we then start one of these injectable weight-loss drugs, then you're preferentially stopping absorption of the progestogen that's coming in orally, but you're allowing plenty of the oestrogen through the skin. 'The rules are very clear that if you give a very high dose of oestrogen and you don't give enough progesterone, however that happens, you're putting that woman at risk of womb cancer,' she said. Prof Mukherjee said there was currently a 'culture of putting women on very high doses of oestrogen', which can make the womb lining thicken. 'It's like having a lawn in a woman's womb. Oestrogen makes the lawn grow. Progestogen cuts the lawn. But if it's not being cut, it grows thicker, and then you can get abnormal cells and cancer.' But she also stressed that the biggest risk factor for womb cancer was obesity and so on the whole the weight-loss injections were a positive tool to reduce weight and cancer risk. 'These drugs reduce the risk of cancer,' she said. 'But if they are prescribed to a woman who's on oestrogen through the skin, and she might already have womb thickening because she's living with obesity, and she's not absorbing the progesterone because she's been put on a weight-loss injection, she's potentially getting loads of oestrogen on top of her thickened womb lining, and that could potentially unmask cancers that are there or drive an early cancer to a more advanced stage.' More than 1.5 million people in the UK are now taking weight-loss jabs, with demand doubling in the last six months. The overwhelming majority are accessing them privately from pharmacies at a cost of around £200 per month. It is not known how many people are on both drugs, but the British Menopause Society has created guidelines after calls from GPs for advice to give to patients. Dr Janet Barter, the president of the Faculty of Sexual and Reproductive Healthcare, said there was 'a small but growing body of evidence that the new diabetes and weight loss drugs, which can bring really positive improvements to people's health, can also cause vomiting and severe diarrhoea in some patients'. 'Obviously this could render any medication, such as HRT tablets or oral contraception, ineffective if there hasn't been enough time for them to be fully absorbed,' she said. 'If these side-effects are occurring, then people should discuss the matter with their doctor or specialist clinician to find the combination of drugs that's right for them.'


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Glasgow Times
19 hours ago
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D-Day landings boosted by import of ‘wonder drug' to Britain, archives reveal
Production of the antibiotic penicillin had struggled to take hold at a large scale in Britain, despite being discovered in 1928 in London by Sir Alexander Fleming. Attempts to produce substantial quantities of medicine from the bacteria-killing mould had not been achieved by the start of the Second World War. Then prime minister Sir Winston Churchill became increasingly frustrated that Britain had not been able to produce enough penicillin in the preparations for the Normandy landings in 1944. Official papers released by the National Archive – containing handwritten notes by Sir Winston – highlight efforts to boost quantities of the antibiotic, with Britain eventually forced to import it from America. The documents were released ahead of the 81st anniversary of D-Day, the Allied invasion of Normandy on June 6, 1944. Official papers highlight the efforts to boost quantities of penicillin (The National Archives/PA) In one report on February 19, after the issue had been raised in the House of Commons, Sir Winston scrawled in red ink on a Ministry of Supply report noting the Americans were producing greater quantities: 'I am sorry we can't produce more.' On another paper, he complained: 'Your report on penicillin showing that we are only to get about one tenth of the expected output this year, is very disappointing.' Elsewhere in the same file he instructs: 'Let me have proposals for a more abundant supply from Great Britain.' With preparations for D-Day ramped up, efforts to deliver enough American-made penicillin for frontline military personnel soon became a matter of urgency. Decisions needed to be made on the quantities of antibiotic imported, how much to administer to individual patients, and how to get medical staff trained in time. Most British doctors did not know how to issue penicillin – until this point, doctors had nothing available to treat infections like pneumonia and many people died of blood poisoning after minor injuries because no drug existed that could cure them. Royal Navy D-Day veteran John Dennett, 101, at the British Normandy Memorial in Ver-sur-Mer to mark the 81st anniversary of the landings (Gareth Fuller/PA) Early in January 1944, Prof FR Fraser, the Ministry of Health's adviser on the organisation of wartime hospitals, wrote that 50,000-100,000 wounded could be expected from the Second Front. He proposed the Emergency Medical Services might need as many as five billion units of penicillin per month for this. Further documents show discussions on whether the antibiotic should be supplied as calcium or sodium salts, or in tablet form. Ultimately, it was agreed powdered calcium salts would be issued for superficial wounds and sodium salts for use in deep wounds. On May 24 1944, less than a fortnight before D-Day, Prof Fraser reported: 'Sufficient supplies of penicillin are now available for the treatment of battle casualties in EMS hospitals, but not for ordinary civilian patients.' Plans were made for casualties from the frontline in France to be brought back to coastal hospitals in Britain for treatment. A week before D-Day, on May 30 1944, hospitals were instructed to treat battlefield patients en route: 'In an endeavour to prevent the development of gas gangrene and sepsis in wounds the War Office have arranged for the treatment of selected cases by penicillin to be commenced as soon after injury as possible.' Military reenactors watch the sunrise over Gold Beach in Arromanches-les-Bains, Normandy, on the 81st anniversary of the D-Day landings (Gareth Fuller/PA) Injections of penicillin were to be given to them at intervals of not more than five hours and patients would be wearing a yellow label with the letters 'PEN'. The time and size of penicillin doses should be written on it, they were told. Dr Jessamy Carlson, modern records specialist at the National Archives, said: 'File MH 76/184 gives a glimpse into the extraordinary levels of preparation undertaken in advance of the D-Day landings. 'Only six weeks before, penicillin is just reaching our shores in quantities which will allow it to play a major role in improving the outcomes for service personnel wounded in action.' As Allied forces made inroads into Europe, restrictions on the use of penicillin for civilians began to relax, but only in special cases. In July 1944, Ronald Christie, professor of medicine, wrote to Prof Fraser to tell him: 'The War Office approves of American penicillin being used for medical conditions in service patients and for air raid casualties among civilians.' On the home front, demand for the new 'wonder' drug began to increase, according the National Archives. It was decided that penicillin for civilians should only be supplied to larger hospitals where the staff had been properly trained to administer it. Only in 1946 did it become fully available for the general public.