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Anti-obesity drug war heats up as Wegovy and Mounjaro boost sales
Sanket Koul New Delhi
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The battle between two global majors vying for a larger pie of the Rs 628-crore Indian anti-obesity market is set to intensify, even as demand and sales for weight-loss drugs rise in a country with the third-highest number of people living with obesity.
India has 254 million people with generalised obesity and 351 million with abdominal obesity, according to the Indian Council of Medical Research–INDIAB (India Diabetes) study.
This segment has been in demand with the India launch of Eli Lilly's Mounjaro (tirzepatide) in March and Novo Nordisk's Wegovy (semaglutide) last month. While the former is currently priced between Rs
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News18
3 hours ago
- News18
Hormonal Imbalance: Why So Many Indian Women Are Feeling ‘Off'
Last Updated: Hormonal imbalances are no longer rare or limited to a certain age group, they are a growing concern for Indian women across generations and regions. More and more Indian women today are experiencing signs that something's just not right—irregular periods, unexpected weight gain, constant tiredness, mood swings, and more. These symptoms often point to hormonal imbalances, a growing yet under-discussed health issue. Despite how common these problems are, awareness is still lacking, especially in rural areas, and many women go undiagnosed for years. What Is Hormonal Imbalance? Hormones are your body's messengers. Produced by glands like the thyroid, ovaries, and adrenal glands, they help control everything from mood and metabolism to sleep and reproduction. A hormonal imbalance occurs when these messengers are produced in too little or too much quantity, or when their signals get disrupted. The result? A ripple effect that can throw off your body's normal functions. Some of the most common hormone-related conditions among Indian women include PCOS (Polycystic Ovary Syndrome), thyroid disorders, and menopausal transitions. Each comes with its own set of challenges and affects women differently based on age, genetics, and lifestyle. How Common Are Hormonal Imbalances in India? From PCOS in young adults to thyroid issues and menopause-related struggles, data reveals that these aren't isolated health problems; they are affecting millions across age groups and geographies. Here's a closer look at the key conditions and what the numbers say. PCOS tops the list when it comes to hormonal disorders among Indian women aged 15–45. A 2023 study in the Indian Journal of Endocrinology and Metabolism estimates that 9–22% of women in this age group are affected, with urban areas seeing rates as high as 26%. The condition is marked by excess androgens (male hormones), irregular periods, and ovarian cysts. It can lead to infertility, acne, and hirsutism (excessive facial/body hair). The same study also highlights that 30–40% of women with PCOS in India have insulin resistance, making them more vulnerable to type 2 diabetes and heart issues. Worth noting: While genetics are involved, poor diet, lack of physical activity, and exposure to environmental triggers like pollution may be increasing the risk. However, more India-specific research is still needed. Thyroid Disorders Thyroid issues, especially hypothyroidism (when the thyroid gland doesn't make enough thyroid hormones to meet your body's needs), are another widespread concern. According to a 2021 study in the Journal of Clinical and Diagnostic Research, about 10–15% of Indian women face thyroid dysfunction, with hypothyroidism being more common than an overactive thyroid. Fatigue, depression, and unexplained weight gain are often brushed off as lifestyle problems but can signal deeper hormonal issues. The study also notes higher prevalence in coastal and iodine-deficient regions like parts of North India. Important detail: Autoimmune thyroid disorders like Hashimoto's are on the rise too, possibly due to urban stress and lifestyle shifts. Menopause And Perimenopause Menopause is a natural hormonal shift that happens between the ages of 45 and 55, but the symptoms often start earlier, during perimenopause. A 2022 study in the Journal of Mid-Life Health found that 60–70% of Indian women experience noticeable symptoms like hot flashes, disturbed sleep, and mood changes during this transition. Unfortunately, due to cultural silence around menopause, many suffer without proper help, especially in rural areas where awareness and access to treatment are limited. Key issue: Hormone therapy (HRT), which can ease severe symptoms, is rarely used in India due to its cost and stigma. Other Hormonal Disorders Less frequent, but still impactful, are conditions like Cushing's syndrome or Addison's disease. A 2020 review in the Indian Journal of Medical Research estimates that about 1–2% of Indian women are affected by such adrenal disorders, which can cause major fatigue, blood pressure changes, and abnormal weight gain or loss. Hormonal issues are rising fast, and it's not just genetics. Urban stress, poor diets, lifestyle shifts, and environmental factors are throwing things off balance. Lifestyle And Urbanisation Urban life has brought convenience but also complications. A 2023 study in The Lancet Regional Health – Southeast Asia found that obesity is rising rapidly among urban Indian women, with 25–30% now classified as overweight or obese. Sedentary routines, processed foods, and chronic stress are major triggers, especially for PCOS and thyroid issues. Genetic And Environmental Factors Genetics does play a big role. A 2021 article in the Indian Journal of Endocrinology and Metabolism pointed out that South Asian women, including Indians, are more genetically prone to insulin resistance and PCOS. On the environmental front, exposure to endocrine-disrupting chemicals in everyday items—like plastic containers and pesticides—may also be influencing hormone health. However, more data is needed in the Indian context. Dietary Shifts We're slowly shifting from traditional Indian meals full of fibre, legumes, and home-cooked veggies to fast foods and sugary snacks. A 2022 study in Nutrition and Diabetes links poor diets and micronutrient deficiencies—like lack of iodine or magnesium—to rising rates of PCOS and thyroid issues. Stress and Mental Health The non-stop pace of urban life is taking its toll. Chronic stress triggers high cortisol levels, which can mess with insulin, thyroid, and reproductive hormones. According to a 2020 survey by the Indian Psychiatric Society, stress and anxiety levels in women—especially during and after the pandemic—are sharply rising, often making hormonal symptoms worse. Limited Healthcare Access In rural India, reaching the right doctor or even getting basic blood tests done is still a challenge. The National Family Health Survey-5 (2019–2021) shows that while 80% of urban women have regular access to healthcare, only 60% in rural areas do. This gap means many cases go undiagnosed and untreated. Symptoms and Impact Hormonal imbalance symptoms are wide-ranging and often overlap with other conditions, making them hard to pinpoint. But some common ones include: These symptoms don't just affect the body—they impact mental health, work, relationships, and quality of life. A 2023 study in Human Reproduction found that 40% of Indian women with PCOS also struggle with anxiety or depression, especially due to fertility-related stress. Diagnosis And Treatment Getting the right diagnosis early can make a huge difference. But many women delay medical help, often due to stigma or assuming their symptoms are 'normal." Standard diagnostic tools include: Blood tests (to check hormone levels, insulin, thyroid function) Ultrasounds (especially for PCOS) Full medical history reviews Treatment depends on the condition, but often includes: PCOS: A mix of lifestyle changes (diet, exercise), medications like metformin, and hormonal pills for period regulation Thyroid Disorders: Thyroid hormone replacements (levothyroxine) or drugs to suppress an overactive thyroid Menopause: In severe cases, hormone replacement therapy (HRT), though often replaced with lifestyle changes like yoga or supplements in India A 2022 review in the Journal of Postgraduate Medicine highlights how powerful simple lifestyle changes—healthy eating, staying active, and managing stress—can be in improving symptoms across the board. Challenges and the Way Forward There's still a lot of stigma around talking about periods, fertility, or menopause. Many symptoms are brushed off as 'just part of being a woman." But this mindset delays diagnosis and treatment. To move forward, experts suggest: Routine screenings: Especially for women with a family history of thyroid or PCOS Lifestyle focus: Encouraging regular activity and traditional balanced diets top videos View all More awareness: Campaigns and open conversations to normalise hormonal health issues Public health programs, like those led by the Indian Ministry of Health and Family Welfare, are trying to close the gap, but there's still a long way to go. About the Author Surbhi Pathak Surbhi Pathak, subeditor, writes on India, world affairs, science, and education. She is currently dabbling with lifestyle content. Follow her on X: @S_Pathak_11. The News18 Lifestyle section brings you the latest on health, fashion, travel, food, and culture — with wellness tips, celebrity style, travel inspiration, and recipes. Also Download the News18 App to stay updated! tags : hormonal imbalance view comments Location : New Delhi, India, India First Published: July 13, 2025, 09:44 IST News lifestyle Hormonal Imbalance: Why So Many Indian Women Are Feeling 'Off' Disclaimer: Comments reflect users' views, not News18's. Please keep discussions respectful and constructive. Abusive, defamatory, or illegal comments will be removed. News18 may disable any comment at its discretion. By posting, you agree to our Terms of Use and Privacy Policy.
Time of India
5 hours ago
- Time of India
Most truckers suffer hearing loss: Study
Lucknow: The constant hum of engines, blaring horns, and relentless traffic noise is quietly damaging the hearing of long-distance truck drivers. A new study found that over half of the drivers tested showed signs of hearing loss—even in their better-hearing ear. Published in the Jan–Feb 2025 issue of Noise & Health, the study was conducted by Anupam Mehrotra (AKTU), Sheo P. Shukla (Rajkiya Engineering College Banda), and Prof Manish K. Manar (KGMU). The team tested the hearing of 200 male long-distance truck drivers from Lucknow using pure tone audiometry. Results showed 50.5% had hearing loss in their better ear. The right ear was more affected in 73.5% of cases (147 drivers), 14% (28) had loss in both ears, and 12.5% (25) in the left ear. "This may be because the right ear is closer to the window while driving," said Prof Manar of KGMU's community medicine department. At 4000 Hz—typically the first frequency affected by Noise-Induced Hearing Loss (NIHL)—abnormal thresholds were found in 84% of right ears. Lead author Anupam Mehrotra explained that normal hearing ranges from 0 to 25 decibels (dB). Lead author Anupam Mehrotra explained that normal hearing ranges from 0 to 25 decibels (dB). "The average threshold was 32.61 dB in the right ear and 28.66 dB in the left—both above the normal range," Prof Manar added. Risk factors included poor sleep, longer driving experience, and age. Drivers sleeping less than six hours or with over 10 years of experience had more damage. Those above 40 had age-related compounding effects. "Lifestyle habits like poor sleep and alcohol use increase vulnerability," said researcher Arvind K Shukla. While past Indian studies focused on car or auto-rickshaw drivers, truckers—who endure prolonged noise—remain under-researched. "This is among the first major studies on hearing loss in Indian truck drivers," said Mehrotra. "We hope it encourages action from transport companies and health authorities." The team recommended regular hearing check-ups, use of earplugs or noise-cancelling devices, awareness drives, and better working conditions to reduce fatigue. "Our truck drivers are the backbone of the economy," Mehrotra added. "Protecting their hearing is vital for their well-being and the nation's functioning."
Time of India
6 hours ago
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Olive oil trend vs mustard oil tradition: Which is better for Indian kitchens? Nutritional value, health benefits
Cooking oils play an essential role not just in the flavor of our meals but also in supporting our health. Among the most widely used and debated options are mustard oil, a staple in Indian kitchens, and olive oil, which has gained favor due to its association with Mediterranean diets and global health trends. While both offer valuable nutrients and benefits, understanding their differences can help individuals make informed choices. Dr. Hansaji Yogendra, Director of The Yoga Institute has shed light on this. Nutritional Composition and Health Impact Mustard oil is a rich source of monounsaturated fatty acids (MUFA), known for improving heart health by lowering bad cholesterol (LDL) and enhancing good cholesterol (HDL). It also contains omega-3 and omega-6 fatty acids, which are vital for brain function and cardiovascular health. In addition, its high content of vitamin E and antioxidants supports immunity and skin health. Similarly, olive oil is packed with monounsaturated fats and contains vitamins E and K. The presence of powerful antioxidants like oleocanthal and oleuropein gives it anti-inflammatory and protective qualities against chronic diseases. Health Benefits at a Glance Mustard oil has traditionally been praised for promoting heart health and reducing inflammation. It supports digestion, increases appetite, and even exhibits antimicrobial properties that are useful for skin and scalp care. On the other hand, olive oil has been found to help lower the risk of cardiovascular diseases, improve brain health, and act as a natural skin moisturizer. Both oils offer significant health-promoting properties, but their suitability depends on individual health needs and dietary preferences. Usage in Cooking Mustard oil remains a favorite in Indian households due to its pungent aroma and versatility. It is commonly used for frying, sautéing, and especially pickling, owing to its natural preservative properties. In contrast, olive oil is more suited to drizzling on salads, preparing dressings, and cooking at low to medium temperatures. Extra virgin olive oil is particularly favored for its nutritional density and flavor. Points to Consider Despite its benefits, mustard oil contains erucic acid, which may pose health concerns if consumed excessively. Choosing cold-pressed variants is recommended to mitigate this risk. Additionally, its sharp flavor may not appeal to all palates. Olive oil, although rich in nutrients, comes with a higher price tag and a lower smoke point, making it unsuitable for high-heat Indian cooking styles. While olive oil aligns with modern health trends and offers several protective benefits, mustard oil continues to be deeply rooted in Indian culinary traditions. Its ideal balance of fatty acids helps in managing blood pressure and preventing hypertension. Regardless of the oil chosen, moderation and purity are crucial. Limiting intake to about two tablespoons a day and opting for cold-pressed or extra virgin variants ensures maximum health benefits. Both oils can complement a balanced diet when used mindfully and according to one's cooking needs.
