logo
Scientists Are Learning to Rewrite the Code of Life

Scientists Are Learning to Rewrite the Code of Life

New York Times2 days ago
At the heart of all life is a code. Our cells use it to turn the information in our DNA into proteins. So do maple trees. So do hammerhead sharks. So do shiitake mushrooms. Except for some minor variations, the genetic code is universal.
It's also redundant. DNA can code for the same building block of proteins in more than one way. Researchers have long debated what purpose this redundancy serves — or whether it's just an accident of history.
Thanks to advances in genetic engineering, they can now do more than just argue. Over the past decade, scientists have built microbes with smaller codes that lack some of that redundancy. A new study, published Thursday in the journal Science, describes a microbe with the most streamlined genetic code yet.
Remarkably, the engineered bacteria can run on an abridged code, making it clear that a full genetic code isn't required for life.
'Life still works,' said Wesley Robertson, a synthetic biologist at the Medical Research Council Laboratory of Molecular Biology in Cambridge, England, and an author of the new study.
Our DNA is built from four different molecular building blocks, called bases: adenine, thymine, guanine and cytosine. A sequence of hundreds or thousands of these bases — known in brief as A, T, C and G — forms a gene. Our cells translate the sequence of bases in genes to make proteins.
Want all of The Times? Subscribe.
Orange background

Try Our AI Features

Explore what Daily8 AI can do for you:

Comments

No comments yet...

Related Articles

Ancient Rivers Under Antarctica Could Slow Down Melting
Ancient Rivers Under Antarctica Could Slow Down Melting

Yahoo

time8 hours ago

  • Yahoo

Ancient Rivers Under Antarctica Could Slow Down Melting

The ice caps which cover our planet's poles are key to understanding global weather patterns and changing climate. But we still don't have a complete understanding of how they work, and what goes on beneath the frozen surface. A group led by researchers at the UK's University of Durham used radar to glimpse beneath the coast of East Antarctica. In a new study, they announced their findings: Ancient riverbeds beneath Antarctica control the behavior of the ice sheet above them. Reconstructing ancient landscapes It is crucial to understand how much, and how quickly, the East Antarctic Ice Sheet is going to melt as temperatures continue to rise. It's the largest of Antarctica's three ice sheets, and it contains enough water to raise the sea level by over 50 meters. The behavior of an ice sheet depends on more than just surface conditions. The landmass hidden beneath the ice impacts how quickly it melts and where it collapses. To get an idea of what that hidden landscape looks like, researchers analyzed a series of radar scans covering 3,500km of East Antarctica. The scans found what was once a coastal plain formed by fluvial erosion. Between 80 million years ago, when Antarctica divorced Australia, and 34 million years ago when it became covered in ice, rivers flowed across East Antarctica and into the sea. Those rivers carved out a smooth, flat floodplain all along the coast. Breaking up the plain are deep narrow troughs in the rock. These plains covered about 40% of the area they scanned. This find confirms previous, fragmentary evidence for a very flat, even plain beneath the icy expanse. Hopeful findings This is good news for those of us who enjoy not being underwater. Computer programs modeling future climate behavior now have more data to work on. Before, as the study's lead author, Dr. Guy Paxton, said in a Durham press release, "The landscape hidden beneath the East Antarctic Ice Sheet is one of the most mysterious not just on Earth, but on any terrestrial planet in the solar system." Understanding the terrain beneath the ice makes it much easier to understand how and where the ice will move. 'This in turn will help make it easier to predict how the East Antarctic Ice Sheet could affect sea levels.' More than that, however, the ancient fluvial plains may be slowing down the melt. The study suggests that the flat plains may be acting as barriers to ice flow. Fast-moving glaciers pass through the deep channels, but the bulk of the ice, atop the plains, is moving much more slowly. Ultimately (as they always do), researchers stressed the need for more investigation. Further studies would involve drilling all the way through the ice and taking samples of the rock below. So look forward to that. Solve the daily Crossword

What's the Difference Between a Gene and a Chromosome?
What's the Difference Between a Gene and a Chromosome?

Health Line

time14 hours ago

  • Health Line

What's the Difference Between a Gene and a Chromosome?

Genes are segments of DNA (deoxyribonucleic acid) that are located inside every human cell. The DNA inside each cell is tightly coiled in structures called chromosomes. Each chromosome contains a single thread of DNA with many different genes. The genes provide instructions for different traits, such as eye or hair color, or male or female sex. Chromosomes come in pairs. Humans have 46 chromosomes, in 23 pairs. People inherit chromosomes from their parents. A child gets one of each pair of chromosomes from their mother and one of each pair of chromosomes from their father. The term ' genetic inheritance ' is the passing down of DNA from parents to children. What is a genetic disorder? Genetic disorders, such as Down syndrome or cystic fibrosis, occur when: there's a change (mutation) in a gene on a chromosome a chromosome is missing a part (called a deletion) when genes move from one chromosome to another (called a translocation) when a cell has extra chromosomes or missing chromosomes A worldwide gene research project, called the Human Genome Project, is creating a map of all human genes and their location on chromosomes. Doctors hope to use this map to find and treat genetic disorders. What do genes and chromosomes have to do with your health? Genes are involved in almost every human trait and disease. They influence how your body responds to: certain health conditions, such as infections medications treatments for health conditions certain behaviors, such as smoking or alcohol use The more we understand how genes affect our health or are linked to disease, the earlier doctors can respond to diseases and provide more effective targeted treatments.

Nearby super-Earth K2-18 b may be a water-rich ocean planet: 'This has certainly increased the chances of habitability'
Nearby super-Earth K2-18 b may be a water-rich ocean planet: 'This has certainly increased the chances of habitability'

Yahoo

time16 hours ago

  • Yahoo

Nearby super-Earth K2-18 b may be a water-rich ocean planet: 'This has certainly increased the chances of habitability'

When you buy through links on our articles, Future and its syndication partners may earn a commission. The saga surrounding Neptune-size "super-Earth" exoplanet K2-18 b just got a whole lot more interesting. For a quick recap, this is the world a team of scientists recently suggested could host life — to the dismay of other scientists in the community, who felt the announcement failed to include necessary caution. While signs of life on the world have failed to conclusively present themselves to the James Webb Space Telescope (JWST), the powerful space telescope has discovered that this planet is so rich in liquid water that it could be an ocean, or "Hycean" world. "This has certainly increased the chances of habitability on K2-18 b" Nikku Madhusudhan, the University of Cambridge scientist behind the original K2-18b discovery as well as the new study, told "This is a very important development and further increases the chance of a Hycean environment in K2-18 b. It confirms K2-18 b to be our best chance to study a potential habitable environment beyond the solar system at the present time." The story regarding the habitability of K2-18 b began back in April 2025, when Madhusudhan and fellow researchers from the University of Cambridge announced they had found what they called the "strongest evidence yet" of life beyond the solar system around this distant super-Earth (it's around nine times as massive as our planet). The evidence came from the tentative detection of molecules that, when found in the atmosphere of Earth, are typically the result of biological processes of living things. The pressure was then on to confirm these potential biosignatures: dimethyl sulfide and dimethyl disulfide. The team set about this by observing four separate instances of K2-18 b crossing, or "transiting," the face of its parent red dwarf star, located about 124 light-years away, during its roughly 33-Earth-day orbit. Because chemicals absorb and emit light at characteristic wavelengths, when light from a parent star passes through a planet's atmosphere, the molecules in that atmosphere leave their telltale fingerprints in the spectrum of starlight. "With four additional transit observations using JWST, we have measured the spectrum of K2-18 b's atmosphere with unprecedented precision," Renyu Hu, the new study's team leader and a NASA Jet Propulsion Lab scientist, told "The spectrum allowed us to conclusively detect both methane and carbon dioxide in the planet's atmosphere and to constrain their abundances. This information points to a planet with a water-rich interior." Hu explained that the team searched for signals of dimethyl sulfide and other organic sulfur molecules in the spectrum using several independent models, but did not find conclusive evidence for their presence. "This was not necessarily disappointing," Hu continued. "We're excited about establishing the planet's water-rich nature." Is K2-18 b a ocean world? Saying it's now confirmed that K2-18 b is water-rich, Hu explained that the next step is to discover if the planet possesses a global liquid water ocean. Ironically, one of the most positive signs of such an ocean is the fact that the atmosphere of this super-Earth appears to lack water vapor. "The spectrum we obtained does not show signs of water vapor. If the atmosphere truly lacks water, this suggests that water has been depleted — most likely through condensation," Hu said. "On Earth, this process is known as the 'cold trap,' and geoscientists consider it essential for retaining water over billions of years by preventing it from escaping to space. "Observing a similar process on an exoplanet would be very exciting. Rigorously confirming the absence of water can by itself be a scientifically important goal for future observations," Hu said. However, Hu cautioned that the spectrum detected by the JWST could also be explained by an alternative model in which the atmosphere actually contains abundant water vapor. Establishing whether K2-18 b and other similar temperate, sub-Neptune-sized planets possess liquid water oceans, Hu says, will also require detecting the presence of a broader set of atmospheric gases beyond methane and carbon dioxide. It would also require an absence of molecules like ammonia, carbon monoxide and sulfur dioxide, which, as of yet, have indeed not been detected in the atmosphere of K2-18 b "This conclusion is based on theoretical work by my group and several others," Hu added. "With the new observations providing valuable context, we've summarized these insights into a roadmap to help guide future observations and studies." Meanwhile, the search for the biosignatures, dimethyl sulfide and dimethyl disulfide, is far from done; while not hitting the significance level required for a confirmation, this research did provide a stronger signal from these molecules than were provided by previous examinations. "The evidence for dimethyl sulfide in the present work is significantly higher than what we had with our previous observations in the same near-infrared wavelength range," Madhusudhan said. "However, this evidence is still not high enough to claim a conclusive detection. "We also need to be able to distinguish dimethyl sulfide from other possible contributors, such as methyl mercaptan, which is also a biosignature on Earth." Related Stories: — The mystery of how strange cosmic objects called 'JuMBOs' went rogue — These mysterious objects born in violent clashes between young star systems aren't stars or planets — James Webb Space Telescope dives into the atmosphere of a mystery rogue planet or failed star It looks certain that K2-18 b will continue to hold the interest of astronomers for some time. "It is great that we are able to infer tentative signs of potential biosignatures with current JWST observations, but significantly more time is needed for conclusive detections. A key question is whether the atmosphere contains one or more biosignatures," Madhusudhan said. "At the same time, extensive theoretical and experimental efforts are needed to robustly identify biological and non-biological pathways for candidate biosignature molecules." One thing the team is sure of, though, is the progress made thus far in the study of K2-18 b wouldn't have been possible without the JWST. And, the $10 billion space telescope is set to play a key role in the future investigation of this super-Earth. "Our observations and analyses add to the growing list of exciting discoveries that highlight the truly transformative science enabled by JWST," Hu concluded. "While we found its Near-Infrared Spectrograph [NIRSpec] particularly well suited to address the goals of our study, other JWST instruments or observational modes could provide complementary and highly valuable information to further enhance our understanding of this planet." The team's research is available as a preprint on the paper repository arXiv. Solve the daily Crossword

DOWNLOAD THE APP

Get Started Now: Download the App

Ready to dive into a world of global content with local flavor? Download Daily8 app today from your preferred app store and start exploring.
app-storeplay-store