Baby girl becomes first child in UK to be born from womb transplant
A baby girl has become the first child in the UK to be born from a womb transplant.
Grace Davidson, who received the transplant in 2023, said the birth of her daughter Amy Isabel was the "greatest gift we could ever have asked for".
The 36-year-old, from north London, received the donated womb from her older sister, Amy.
It was the first time the procedure had taken place in the UK, and the birth will give hope to thousands of women born without a womb - like those with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome - or whose womb fails to function.
Amy Isabel was named after her aunt, and a surgeon who helped perfect the technique, and was born by planned caesarean section on 27 February at Queen Charlotte's and Chelsea Hospital in London.
Mrs Davidson, an NHS dietitian, said she felt "shock" when she first held her daughter, adding: "We have been given the greatest gift we could ever have asked for.
"It was just hard to believe she was real. I knew she was ours, but it's just hard to believe.
"It sort of feels like there's a completeness now where there maybe wasn't before."
Her husband Angus, 37, said: "The moment we saw her was incredible, and both of us just broke down in emotional tears - it's hard to describe, it was elation.
"It had been such a long wait. We'd been intending to have a family somehow since we were married, and we've kind of been on this journey for such a long time."
Womb transplantation is on the way to becoming an acceptable, life-giving procedure
Science and technology editor
@t0mclark3
The birth of Amy Isabel is not just a first for the UK, but an important step towards womb transplantation becoming an established medical procedure.
It was little more than a decade ago that the world's first baby was born following a womb transplant in Sweden.
And not without eyebrows being raised by some in the world of medical ethics.
Not all womb transplants, whether from a living relative or from a deceased donor, are successful. And not all result in successful or uncomplicated pregnancies.
But the surgical team behind this UK success have achieved a one-for-one: a healthy baby born from the first womb transplant ever performed here.
Amy Isabel joins an estimated 50 other babies and children worldwide now born via a womb transplant.
And she won't be the last.
Around 100 women in at least 10 countries have undergone the procedure – three transplants have taken place in the UK since Amy's mother became the first in 2023.
A study of 33 womb transplants in the US found 74% of the transplants remained healthy after a year and 80% of those resulted in a successful birth.
But a womb transplant is unlikely to ever become "routine".
While the number of eligible women – those lacking a functioning uterus but having healthy ovaries – might number in the low thousands in a country the size of the UK, not all would meet the strict medical criteria needed to maximise the chance of a successful transplant and subsequent birth.
And not all might choose it.
A successful birth following a womb transplant involves three major operations. The first to receive the transplanted womb, a caesarean section to deliver the baby, then a hysterectomy to remove the womb once the recipient mother decides to have no more children.
Given a womb transplant isn't "life-saving", ethics guidelines require the procedure to be temporary. The long-term risks of organ rejection, and the drugs needed to prevent it, are considered too great once the womb has served its miraculous function.
Some medical ethicists still question the procedure as a whole, arguing it is unnecessarily risky for both the mother and baby, especially babies are born seriously pre-term and at low birth weight.
However, this latest success, and the increasing number of healthy babies born via the procedure worldwide may change that.
Womb transplantation is on the way to becoming an acceptable, life-giving procedure for women who previously had no hope of carrying a baby of their own.
Mrs Davidson was born with Mayer-Rokitansky-Kuster-Hauser, a rare condition that affects around one in every 5,000 women. It means they have an underdeveloped or missing womb.
However, the ovaries are intact and still function to produce eggs and female hormones, making conceiving via fertility treatment a possibility.
Before receiving the donated womb, Mrs Davidson and her husband underwent fertility treatment to create seven embryos, which were frozen for In Vitro Fertilisation (IVF) in central London.
Mrs Davidson had surgery in February 2023 to receive the womb from her 42-year-old sister, who is a mother to two girls aged 10 and six, and who called the birth of her niece "worth every moment".
Several months later, one of the stored embryos was transferred via IVF to Mrs Davidson.
The baby weighed 4.5lbs and was delivered several weeks early to ensure a safe, hospital-based delivery.
Professor Richard Smith and Isabel Quiroga were the lead surgeons for the womb transplant and both were in the operating theatre when Amy was delivered, with her parents choosing her middle name in honour of Ms Quiroga.
Prof Smith, clinical lead at the charity Womb Transplant UK and consultant gynaecological surgeon at Imperial College Healthcare NHS Trust, told Sky News that being in the operating theatre when Amy was delivered was "really quite remarkable".
The medic said: "We've waited a very, very long time for this, and there's been quite a lot of tears shed. Ironically the scariest bit of the day for me was when [Amy's] mum and dad asked me to hold their baby, which was incredible."
Ms Quiroga, consultant surgeon at the Oxford Transplant Centre, part of Oxford University Hospitals, told Sky News it was "quite a complex procedure" and "the pressure was immense when we did the transplant".
Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles
The Independent
an hour ago
- The Independent
Chancellor unveils £6bn NHS funding after health-centred spending review
Some £6 billion will be spent on speeding up testing and treatment in the NHS, Rachel Reeves has announced, after she placed the health service at the heart of Government spending plans. The Chancellor unveiled the investment, which includes new scanners, ambulances and urgent treatment centres aimed at providing an extra four million appointments in England over the next five years, after Wednesday's spending review. The funding is aimed at reducing waiting lists and reaching Labour's 'milestone' of ensuring the health service carries out 92% of routine operations within 18 weeks. In the review, Ms Reeves set out day-to-day spending across Government for the next three years, as well as plans for capital investment over the next four years. The NHS and defence were seen as the winners from the settlement, as both will see higher than average rises in public spending. This comes at cost of squeezing the budgets of other Whitehall departments and experts have warned tax rises may be needed later this year. The Chancellor and Sir Keir Starmer both sought to portray the review as a 'new phase' for the Government, following the criticism Labour has faced during its first year in power, including over cuts to winter fuel allowance. Ms Reeves claimed the NHS had been 'put on its knees' as a result of under-investment by the previous government, adding: 'We are investing in Britain's renewal, and we will turn that around.' The new £6 billion investment will come from the capital settlement for the NHS and will also help to speed up diagnoses with scans and treatment available in places such as shopping centres and high streets. The scale of day-to-day spending for the NHS is akin to an extra £29 billion a year. In a broadcast interview on Wednesday evening, Ms Reeves said the Government was 'confident' it could meet its pledge to reduce waiting lists after the boost to NHS spending. But while health and defence have benefited from the review, the Home Office, Ministry of Housing, Communities and Local Government, Department for Culture, Media and Sport, Department for Transport and Department for the Environment, Food and Rural Affairs are all in line for real-terms cuts in day-to-day spending. The Foreign Office is also in line for real-terms cuts, mainly as a result of a reduction in the overseas aid budget, which was slashed as part of the commitment to boost defence spending to 2.6% of gross domestic product – including the intelligence agencies – from 2027. Ms Reeves acknowledged 'not everyone has been able to get exactly what they want' following Cabinet squabbling over departmental budgets. She said 'every penny' of the spending increases had been funded through the tax and borrowing changes she had announced in her first budget. The Chancellor also insisted she would not need to mount another tax raid to pay for her plans, but experts warned the money for the NHS might still not be enough and the Government is under international pressure to boost defence funding further. Paul Johnson, of the Institute for Fiscal Studies, described the hospital waiting times target as 'enormously ambitious', adding: 'And on defence, it's entirely possible that an increase in the Nato spending target will mean that maintaining defence spending at 2.6% of GDP no longer cuts the mustard.' At a summit later this month Nato members will consider calls to increase spending to 3.5% on defence, with a future 1.5% on defence-related measures. Steven Millard, interim director of the NIESR economic research institute, said the Chancellor's non-negotiable fiscal rules, coupled with the 'small amount of headroom' in her spending plans, meant 'it is now almost inevitable that if she is to keep to her fiscal rules, she will have to raise taxes in the autumn budget'. Elsewhere, policing leaders warned forces may need to make deep cuts after their settlement was announced. The spending review provides more than £2 billion for forces, but ministers have acknowledged some of that 'spending power' will come from council tax hikes.
Scottish Sun
an hour ago
- Scottish Sun
Addiction to ketamine rises eight-fold in a decade as powerful tranquiliser becomes popular with Gen Z
Doctors say heavy use can cause liver disease and permanently damage the bladder and kidneys GENERATION K Addiction to ketamine rises eight-fold in a decade as powerful tranquiliser becomes popular with Gen Z DOCTORS have sounded the alarm over an eight-fold rise in ketamine addiction in a decade. The powerful tranquilliser is popular with Generation Z because of its relatively low cost, experts say. Advertisement 1 Addiction to ketamine has risen eight-fold in a decade, experts have warned Credit: Getty Clinics in England treated 3,609 people of all ages for addiction last year, eight times more than 426 in 2014, figures reveal. Ketamine, also referred to as 'K' or 'Ket', numbs pain and can cause a trippy high. Dealers sell it in powder form for around £20 to £40 a gram compared with £40 to £60 a gram for low-quality cocaine. Doctors say heavy use can cause liver disease and permanently damage the bladder and kidneys. It is linked to constipation, depression and loss of mental sharpness. Advertisement Many medics fail to understand how addictive it can be, an NHS report said. Led by Dr Irene Guerrini of the South London and Maudsley NHS Trust, it called the drug's prevalence 'concerning'. It said: 'As ketamine use increases, more individuals are seeking treatment for addiction. 'Long-term use can seriously harm both physical and mental health, diminishing quality of life, affecting personal relationships and impairing academic or professional performance.' Advertisement Dr Guerrini called for stricter guidelines on how the NHS uses the drug and more funds for treatment and prevention. Ministers are considering uprating 34878330from a Class B to Class A drug.
The Sun
an hour ago
- The Sun
Addiction to ketamine rises eight-fold in a decade as powerful tranquiliser becomes popular with Gen Z
DOCTORS have sounded the alarm over an eight-fold rise in ketamine addiction in a decade. The powerful tranquilliser is popular with Generation Z because of its relatively low cost, experts say. Clinics in England treated 3,609 people of all ages for addiction last year, eight times more than 426 in 2014, figures reveal. Ketamine, also referred to as 'K' or 'Ket', numbs pain and can cause a trippy high. Dealers sell it in powder form for around £20 to £40 a gram compared with £40 to £60 a gram for low-quality cocaine. Doctors say heavy use can cause liver disease and permanently damage the bladder and kidneys. It is linked to constipation, depression and loss of mental sharpness. Many medics fail to understand how addictive it can be, an NHS report said. Led by Dr Irene Guerrini of the South London and Maudsley NHS Trust, it called the drug's prevalence 'concerning'. It said: 'As ketamine use increases, more individuals are seeking treatment for addiction. 'Long-term use can seriously harm both physical and mental health, diminishing quality of life, affecting personal relationships and impairing academic or professional performance.' Dr Guerrini called for stricter guidelines on how the NHS uses the drug and more funds for treatment and prevention. Ministers are considering uprating 34878330from a Class B to Class A drug.
