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Instagram and TikTok may launch apps for TVs.

Instagram and TikTok may launch apps for TVs.

The Verge10 hours ago

Instagram and TikTok may launch apps for TVs.
YouTube is a hit on TVs, and Meta and TikTok are looking to get in on that battleground, The Information reports. What will launch first: Instagram for TV or Instagram for iPad?

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Why the best leaders embrace both ‘agile' and ‘waterfall' thinking
Why the best leaders embrace both ‘agile' and ‘waterfall' thinking

Fast Company

time13 minutes ago

  • Fast Company

Why the best leaders embrace both ‘agile' and ‘waterfall' thinking

Have you ever admired a leader so dialed into their long-term mission that it seems nothing can shake their focus? Every move appears premeditated, every milestone perfectly timed. Now think about a leader who seems to always be in step with the moment. Their company launches timely features, aligns instantly with market shifts, and always feels fresh. For every leader who succeeds through single-minded focus, there are others whose obstinacy has led them and their organizations to arrive at a destination that is no longer desirable. And while adaptability can be a gift, it also leads many organizations to shift strategies with each change in the winds without ever hitting on a true contribution. This tension between structure and adaptability isn't just theoretical; it's a foundational dynamic that has shaped industries for decades. Approaches to enterprise software development provide a useful way to gauge whether you're leaning too far in either direction. Balancing Your Leadership Approaches Early on in the history of the software industry, a 'waterfall' strategy reigned supreme. Road maps guided development, with possible major platform releases happening every one to two years, version releases quarterly, feature sets monthly, and bug fixes weekly. Teams operated with near-military precision towards long-term goals, broken down into shorter term deliverables. But as the pace of change accelerated, that model began to break down. Agile software development emerged, favoring speed, iteration, and real-time user feedback. Short sprints (often 60 to 90 days) determined what was going to be released. Each sprint on a project added features, fixed bugs, and adapted to feedback from the previous release. Unlike with waterfall, employees from across agile teams were empowered to fix things and make many changes without going through their chain of command to get approval. In our coaching work, we've seen that the same push and pull between waterfall and agile playing out in leadership styles and company cultures. Some leaders operate like agile systems: adaptive, fast-moving, iterative, and with a distributed decision structure. They respond quickly to new data and aren't afraid to pivot when the market shifts. Others take a waterfall-inspired approach: structured, methodical, deeply focused on long-term outcomes, and more rigidly hierarchical. They chart a course and stick to it, often prioritizing consistency over speed. Neither mindset is wrong, but over-indexing on either one can create serious blind spots. Agile thinkers risk spinning in circles when they follow the tides. Waterfall thinkers risk charging toward goals that become outdated or foundering on unsolvable problems. For executives, the ability to integrate both approaches is no longer optional—it's essential. Here's how to strike that balance—and why your team's future may depend on it. 1. Assess your own leadership style In our coaching conversations with leaders, we often start by asking them to reflect on whether they naturally lean toward structure or spontaneity. We can expand on their natural preference by administering a personality profile survey as well. Are they more likely to build a road map and stick to it, or pivot at the first sign of change? Developing this self-awareness isn't about labeling or even changing your style—it's about recognizing where you need balance. If you default to agile thinking, ask yourself: Are we making measurable progress? Or changing directions without setting a course? Are we building anything lasting? If you favor waterfall thinking, ask: Is our goal still relevant? What feedback are we ignoring? Which market changes do we need to take into account? During a recent coaching conversation a senior marketing leader at large hospitality company expressed frustrations about her proposed product launch, a new menu item, being challenged by her colleague who runs operations. He thought a different item would be faster, easier, and aligned to what customers recently told him they wanted. Her team had spent the last six months toward brand alignment, market research, product iterations, testing, launch planning, and marketing planning and were now finally ready to do something. Her waterfall approach and his agile approach were in conflict. Both made great points. In the end, they struck a balance between both proposals and management styles. 2. Understand when culture amplifies leadership style As a leader, you have to ask whether your company culture reflects your style or balances it. A culture determines how people behave naturally, on average, even when a leader is 'not in the room.' Do people tend to work in a structured manner, with long-term goals in mind, always talking about progress against objectives? Or, does it feel like people question the current state, proposing new ideas and take initiative without seeking executive approval. Crucially, if the culture leans in a particular direction, how easy and safe is it for people who lean the other way to challenge the others. A lot of can depend on whether the company typically hires and promotes a 'type' that matches the leader's biases or whether it embraces individuals who bring unique perspectives and skills to the workplace. When you build a corporate ethos in your image, you magnify your own tendencies in ways that create a harmonious work environment. People are not likely to argue with your decisions, because they reflect their own opinions as well. Day-to-day, that can be pleasant. In the long-run, though, it creates problems. If the leadership and organization are all Agile, then chaos may manifest. A slow-moving Waterfall culture may stall innovation. Take Boeing as an example; it continued reliance on a hierarchical, Waterfall-style of leadership and development culture has been widely criticized for contributing to recent crises. The rigid, top-down approach delayed necessary changes in engineering and quality control, despite repeated warnings from employees and whistleblowers. The 2024 mid-air panel blowout on an Alaska Airlines 737 MAX reignited scrutiny, and internal documents revealed slow, structured processes that resisted fast adaptation or real-time feedback. The Waterfall mindset—prioritizing schedules, approvals, and internal reporting lines—led to safety risks, brand damage, and regulatory backlash. In contrast, consider Netflix. In the late 1990s, they recognized an inefficiency in the movie rental business. Leaders in this space had significant overhead costs from the physical stores from which people rented and returned movies. By allowing customers to select movies online and have then delivered, they created an economy of scale. Building this business required attention to detail and customer service. Yet, the company remained sensitive to technology trends. They realized that they were essentially sending computer files through a low-bandwidth connection (the U.S. Mail) and disrupted their own business model by pivoting to streaming. Further realizing that many companies could develop streaming models, they pivoted again to content creation. Becoming a content creator requires a lot of expertise, and so they had to implement this model using a more traditional Waterfall approach. This balance between Agile and Waterfall approaches has enabled Netflix to remain a significant force in the market. The takeaway? While a particular cultural and leadership disposition around Waterfall or Agile may be the natural to the organization and may have served it well for many years, great leaders are aware of those tendencies, and build a culture that can challenge the status quote and balance, when needed, Agile and Waterfall approaches to yield healthy (if sometimes uncomfortable) debate. 3. Combine long-term vision with real-time feedback A 2024 meta-analysis in the Journal of Entrepreneurship, Management and Innovation found that agile leadership has a significant impact on organizational outcomes, team effectiveness, collaboration, and innovation. But the key isn't to replace long-term thinking entirely—it's to layer agility on top of it. That's why the most successful leaders use both mindsets. They know when to zoom out—building toward five-year goals—and when to zoom in, listening to customer feedback or shifting based on real-time performance indicators. New Balance has done this exceptionally well, maintaining its long-term manufacturing commitments in the U.S. while evolving its brand to meet changing consumer tastes—a move that helped drive a record $6.5 billion in sales in 2023. A CMO we coached recently calls her approach 'glocal marketing'—the balance between local and global marketing, which includes honoring the long term brand promise (Waterfall) while still connecting, through customization, at the local level to what is relevant and popular at that moment in a particular area (Agile). At the team level, this looks like maintaining a steady mission while adapting tactics. At the leadership level, it means pairing clarity of purpose with the humility to course correct. 4. Build balanced teams that challenge your defaults There's a method in psychology to measure individual tendencies known as need for cognitive closure, and it provides a useful way to think about your own leadership approach. People high in need for closure prefer action to thinking, so they tend to react to situations and engage with available information, which is characteristic of an agile approach. People low in need for closure prefer thinking to action and typically mull over information, which often leads to the focus on long-term goals characteristic of a waterfall style. Understanding your own tendencies as a leader as well as those of your trusted associates is valuable, because it gives you the opportunity to balance your team to include those with a range of levels of need for closure to ensure your team isn't heavily biased toward either the agile or waterfall style. You can measure these tendencies with the Need for Closure scale. It will help you to see whether the people you work with tend toward High (i.e., Agile) or Low (i.e., Waterfall) Need for Closure. If you find that your team tends to be biased more toward reaction or more toward deep thought, you can use timelines to help overcome those tendencies. For example, if your team tends to react quickly, set a deadline for finalizing a decision that's far enough out to allow your team the time and space to slow down and proceed carefully and thoughtfully. In contrast, if your team often deliberates too long and gets stuck in long-term patterns, an earlier deadline can push them to make decisions more quickly. Don't surround yourself with people who think exactly like you. Instead, build teams that stretch your instincts, pressure-test your assumptions, and help you operate at both 30,000 feet and ground level. Often, people's preferences reflect hidden assumptions that they themselves may not be aware of. Being forced to justify your strategic decisions explicitly in conversations brings those assumptions to the forefront. In addition, these strategic choices may sometimes reflect reasoning gaps that these conversations will also bring to light. Navigate with intention The best leaders don't choose between agile and waterfall—they learn to navigate the tension and switch gears with intention. Agility without direction leads to burnout. Direction without agility leads to obsolescence. So, ask yourself: Are you leaning too far in one direction? What conversations, feedback loops, or partners could help you rebalance? Because real leadership isn't about having a single style—it's about learning when to move fast, when to slow down, and how to bring your team with you, every step of the way.

Why Alphabet Stock Crept Higher in Price on Wednesday
Why Alphabet Stock Crept Higher in Price on Wednesday

Yahoo

time14 minutes ago

  • Yahoo

Why Alphabet Stock Crept Higher in Price on Wednesday

The company rolled out a highly popular service in a new city. This extends its lead over a recent arrival to the business. 10 stocks we like better than Alphabet › Like a robotaxi slowly advancing down a street to approach its destination, Alphabet (NASDAQ: GOOG)(NASDAQ: GOOGL) stock advanced on Hump Day. Its two share classes both rose in excess of 2% in price during the trading session, on the back of good news for one of its businesses. That bump higher was good enough to beat the flat S&P 500 (SNPINDEX: ^GSPC) on the day. That Alphabet business posting the positive development was its accelerating robotaxi service, Waymo. On Tuesday, in partnership with ride-sharing incumbent Uber Technologies, the company rolled out Waymo in Atlanta. The Georgia metropolis now becomes the fifth metropolitan area serviced by Waymo (the others are San Francisco and the Bay Area, Los Angeles, Phoenix, and Austin). Alphabet doesn't plan on slamming the brakes on the project anytime soon, as it aims to Waymo Washington, D.C., and Miami next year. The combination of a widening footprint and positive word-of-mouth has boosted Waymo's popularity -- and its ridership. According to recent reporting from Barron's, these days the service is providing over 250,000 rides per week. That's more than double the 100,000 from last year at around this time. With the Atlanta launch, Alphabet extends its lead over ever-ambitious electric vehicle (EV) giant Tesla. That company launched its Robotaxi brand in Austin this past weekend; however, it was limited only to a select group of hand-picked users. Both Alphabet's development and rollout of Waymo feels as if they have been well planned and smoothly executed. In Los Angeles, for example, now it's common to see Waymos ferrying customers around the car-clogged city. While robotaxis aren't yet a massive business for Alphabet, they're looking like they'll become an important revenue generator sooner than many might expect Before you buy stock in Alphabet, consider this: The Motley Fool Stock Advisor analyst team just identified what they believe are the for investors to buy now… and Alphabet wasn't one of them. The 10 stocks that made the cut could produce monster returns in the coming years. Consider when Netflix made this list on December 17, 2004... if you invested $1,000 at the time of our recommendation, you'd have $689,813!* Or when Nvidia made this list on April 15, 2005... if you invested $1,000 at the time of our recommendation, you'd have $906,556!* Now, it's worth noting Stock Advisor's total average return is 809% — a market-crushing outperformance compared to 175% for the S&P 500. Don't miss out on the latest top 10 list, available when you join . See the 10 stocks » *Stock Advisor returns as of June 23, 2025 Suzanne Frey, an executive at Alphabet, is a member of The Motley Fool's board of directors. Eric Volkman has no position in any of the stocks mentioned. The Motley Fool has positions in and recommends Alphabet, Tesla, and Uber Technologies. The Motley Fool has a disclosure policy. Why Alphabet Stock Crept Higher in Price on Wednesday was originally published by The Motley Fool

The Man with the Pig Kidney - Chasing Life with Dr. Sanjay Gupta - Podcast on CNN Podcasts
The Man with the Pig Kidney - Chasing Life with Dr. Sanjay Gupta - Podcast on CNN Podcasts

CNN

time18 minutes ago

  • CNN

The Man with the Pig Kidney - Chasing Life with Dr. Sanjay Gupta - Podcast on CNN Podcasts

Dr. Sanjay Gupta 00:00:08 On January 25th, 2025 Tim Andrews became a medical pioneer. Dr. Sanjay Gupta 00:00:17 He received a pig kidney transplant. Now, while he was not the first, he does hope that his and the contributions of many others means that he also won't be the last. Tim Andrews 00:00:29 Stepping forward, you're gonna do something for humanity. This is a way that we can bring this forward. And this is the hope for all these people that it's gonna be okay. We're gonna find a way. Dr. Sanjay Gupta 00:00:45 It's been an incredible journey of an incredible man and an incredible scientific achievement. And this may only be the beginning. I'm Dr. Sanjay Gupta, and this is part two of Animal Farm. It's been just seven days since Tim Andrews received a pig kidney. Tim Andrews 00:01:10 I'm a crier. They all know it. Dr. Sanjay Gupta 00:01:12 He's understandably emotional. Once tethered to a dialysis machine for survival, Tim is now free. Tim Andrews 00:01:19 Oh, it's nice Dr. Sanjay Gupta 00:01:25 There's that great shot of you as you're walking out of the hospital and you're fresh air in it. It almost seemed like you were breathing air for the first time. Tim Andrews 00:01:34 Yeah, it kind of felt like it had been a long time since I had been outside, really. Dr. Sanjay Gupta 00:01:43 And by leaving the hospital so soon, Tim was making history. Dr. Sanjay Gupta 00:01:47 You wanted to get out as quickly as possible. Yes. And you wanted to be Towana Tim Andrews 00:01:53 Yeah Dr. Sanjay Gupta 00:02:00 'Tawana is Towana Looney, a 53-year-old Alabama grandmother who underwent a pig kidney transplant two months earlier. So how you feeling? Dr. Robert Montgomery was her surgeon. Towana Looney 00:02:12 You know what the first thing I'm gonna do when I get home? What's that? Cook me some greens. Some greens? Like your wife sent me. Dr. Sanjay Gupta 00:02:21 She had been on dialysis for nine years, waiting for an organ transplant. Dr. Robert Mongtomery 00:02:25 If you're on dialysis for five years, you have a 50% mortality. You start going beyond that and your likelihood of living gets less and less. Alright, and the kidney is right inside this bag. Dr. Sanjay Gupta 00:02:41 Towana volunteered for a Xenotransplant. Dr. Robert Mongtomery 00:02:45 It was exciting. She wants to start a revolution, too, herself. I mean, she really believes in this. Dr. Sanjay Gupta 00:02:52 So much so that Towana helped make Tim Andrews a believer as well. Because along the way, when Tim had had his doubts, he called the only living person in the world who had gone through this. Tim Andrews 00:03:04 Hearing her saying, you know, just trust God, just trust God. It'll be okay. That made me feel easier. Dr. Sanjay Gupta 00:03:15 It has now been 60 days since his transplant, and Tim is settling back into life in Concord, New Hampshire. Today, we decided to bundle up and go for a walk. It's interesting because you say you feel better. Dr. Sanjay Gupta 00:03:28 No question about it, right? Tim Andrews 00:03:29 Absolutely no question about it. Dr. Sanjay Gupta 00:03:31 What does that mean exactly? What feels better? Tim Andrews 00:03:35 Energy. I have energy. Whoop. I'm a little wobbly though. Ha ha ha ha. We got you. But I feel so much better and clearer. Dr. Sanjay Gupta 00:03:49 None of this is easy. Taking 20 milligrams, they're fives. I mean, every day Tim sits at this makeshift mountain of medication guided by this big binder. It's a survival Bible of sorts. Tim Andrews 00:04:01 This is the book. Tells you what you're gonna take. We keep it in pencil because it changes a lot. Dr. Sanjay Gupta 00:04:09 Another reminder of how new this all is, there is a lot of experimentation with the right mix of meds and doses. In all, Tim takes 52 pills a day. Tim Andrews 00:04:19 And this is when it helps to be a 70s child. Ready? Dr. Sanjay Gupta 00:04:25 'And several times a week an anti-rejection infusion directly into his blood. We were there for his two-month checkup as he had a battery of tests to look for any signs of infection, rejection, or reduced function. Doctor 00:04:45 We can actually identify if there's any issues with the kidney. Dr. Sanjay Gupta 00:04:49 'Worried about Tim's heart, the Boston medical team is also monitoring him 24-7 with this implanted loop recorder. It measures Tim's cardiac rhythm and warns of any potential abnormalities. Doctor 00:05:01 We're of course being just extra careful and cautious and ensuring things are in the right direction. Tim Andrews 00:05:08 And the little pig is right there so I can pat it. Dr. Sanjay Gupta 00:05:11 Today's visit is all about this moment. Observing this ultrasound, that is an ultrasound of a pig kidney inside Tim. Something that very few people ever get to see. Dr. Leonardo Riella 00:05:21 And it looks exactly like a human kidney, so let me see all the blood flow throughout. Dr. Sanjay Gupta 00:05:27 Is there anything in there that makes. Dr. Sanjay Gupta 00:05:29 It clear that it's a pig kidney? Dr. Leonardo Riella 00:05:30 No, exactly like a human one. Dr. Sanjay Gupta 00:05:32 'And not only does it look like one, eight weeks post-operatively, it's acting like one. Dr. Leonardo Riella 00:05:37 But the level of kidney function is as good as we would expect from a human kidney transplant. We just are amazed every day we look at that blowwork. That's awesome good stuff, isn't it? Tim Andrews 00:05:49 No, no, no. Dr. Sanjay Gupta 00:05:51 Now there is one complication they're watching for very carefully, something that is unique to xenotransplants and could affect not only Tim, but his wife Karen as well, maybe all of us. Dr. Sanjay Gupta 00:06:05 One of the concerns is that if there is some sort of weird or strange virus in the pig and it gets into the human population through one of these transplants, might not only affect the patient, but people around the patient as well. Dr. Leonardo Riella 00:06:16 In all the studies that we're doing, we're not only monitoring the patient, but their close contacts. Tim Andrews 00:06:22 Because we don't know to this day, and we won't know for the rest of my life whether that can happen. So that's always in the background. Dr. Sanjay Gupta 00:06:33 Talking to scientists, this is one of their biggest concerns, accidentally unleashing a pig virus onto a susceptible human population. To avoid that they screen extensively, they even edit the genome of the pigs to inactivate those viruses. But the question is is that enough? Art Kaplan 00:06:53 Genetic engineering is a nice tool, but it's not 100% accurate yet. Dr. Sanjay Gupta 00:06:58 'World-renowned medical ethicist, Art Kaplan. Is it a big enough concern to sort of derail? Art Kaplan 00:07:04 No, I don't think so. I think it's a reason to be cautious, to really detect a problem early and then be able to shut it down or respond. Kathy Guillermo 00:07:14 I think it's a little bit of Russian roulette here. Dr. Sanjay Gupta 00:07:17 Kathy Guillermo is the Senior VP at PETA, People for the Ethical Treatment of Animals, and she thinks this is a big issue. Kathy Guillermo 00:07:25 I think when it comes to viruses and animals, there's so much that we don't know. There are people who, in addition to PETA, are opposed to these experiments for that reason. Dr. Sanjay Gupta 00:07:34 Now to be clear, there is nothing about xenotransplants that sits well with Kathy or anyone else at PETA. Kathy Guillermo 00:07:41 I don't think it could ever be okay to use an animal as a source of spare parts. For that animal, this is a life of deprivation. It's an early death. It's much suffering. And I don't think that's ever okay. Dr. Sanjay Gupta 00:07:56 Even if it means a choice between a pig life or a human death. Kathy Guillermo 00:08:00 'This was a situation my father was presented with, and my father was over 80, so he was not eligible for a transplant. And my father did die of end-stage renal disease, and he would not have taken an organ from a pig for ethical reasons. Art Kaplan 00:08:14 I think what the mainstream position will become among those caring about animals, loving animals, is that we're gonna tolerate this, we're going to look for alternatives to it that they would find more acceptable. Dr. Sanjay Gupta 00:08:31 And then there are the religious concerns. Dr. Sanjay Gupta 00:08:33 You have certain religions, Muslim religion, Jewish religion, who they won't eat pork. They don't eat pigs. Is transplanting a pig organ different in some way than consuming? Art Kaplan 00:08:46 You know, eating it. It's somewhat contentious. I, however, don't think that you're gonna see huge religious opposition. But you may see in some of the Islamic countries is human organs first, only go to the animal last resort. I could see that. Dr. Sanjay Gupta 00:09:04 A spiritual man, Tim also had his concerns. It's why he reached out to his church for guidance. Tim Andrews 00:09:10 I contacted the bishop and then the Vatican sent me a paper. They were working animals who were put on earth. God put them on the earth to serve us. And if they're service extends life and makes a better life, so be it. Dr. Sanjay Gupta 00:09:30 So will these new kidneys create a better and longer life? You look really good when we come back. This is the future of transplantation, a heart, a liver, a kidney. These are organs that are grown, not in the body, but in the lab. David Ayeres 00:10:04 They're using a pig organ scaffold and resellularizing that with human cells. Also another group is 3D printing that scaffold, resellicularizing that with human cell, so multiple ways to generate a humanized organ for overcoming the shortage. Dr. Sanjay Gupta 00:10:22 The potential? Organs on demand. Could you get to the point where you could create a personalized organ for somebody? David Ayeres 00:10:30 Absolutely. Dr. Robert Mongtomery 00:10:31 I think that's gonna be the future. Dr. Sanjay Gupta 00:10:34 So an organ that would be designed for Robert Montgomery. David Ayeres 00:10:37 Personalized organs where we don't have to use any immunosuppression. Somebody starts to develop kidney disease. We take some of their stem cells from a piece of skin or some blood and we start to grow them up and then seed that scaffolding with that person's stem cells that then grow and mature, and then you have a designer organ for that person when they need it. Dr. Sanjay Gupta 00:11:09 'Now to be clear, what he's describing is still years away, and that is why the focus is for now on these genetically modified pigs. Since the time we started investigating xenotransplantation about two years ago, things have taken off at a lightning pace, from compassionate use to a pilot study and now an FDA-approved clinical trial. Also, expect to see high-tech pig farms like these pop up in other places around the country and the world. David Ayeres 00:11:43 The next facility will be built, will have an output of about 6,000 organs per year, but that's still less than 10% of the demand for the unlimited supply of organs. Aaron Ortiz 00:11:55 This is a brand new building built specifically for human clinical trials. Dr. Sanjay Gupta 00:11:59 'Aaron Ortiz is in charge of scaling up United Therapeutics pig production. These are the highly specialized, designated pathogen-free buildings, DPF. They're built using FDA guidelines. It's what they call a bio-secure and pathogen free environment. This is not typical pig farm. Aaron Ortiz 00:12:18 Yeah, it looks like a biotech facility, to be honest, and the mechanics behind it. The pigs are drinking cleaner water than the employees that are working here, and they're breathing cleaner air here as well. Dr. Sanjay Gupta 00:12:29 And within this farm, there are also multiple sterile operating rooms. That's where transplant teams from around the country will come starting this summer to procure or harvest the organs. Aaron Ortiz 00:12:41 The reason we do the procurements here is to mitigate any variabilities that could occur during transport of the animal to the actual hospital site. Dr. Sanjay Gupta 00:12:49 So the concern was if you're actually moving the pig, that's a source of potential contamination. Dr. Sanjay Gupta 00:12:59 This is ultimately the biggest concern we heard from so many people that we interviewed for this documentary. They all ask, can the spread of disease from these pigs to humans really be controlled? And that is crucial, after all, to protect the population at large. Do you feel like at this point that is an achievable goal? Aaron Ortiz 00:13:24 We test them at day 30, we test them day 60, we test them a day 90, we tested quarterly. When they put into quarantine, if they're going for transplant, we will test them when they're in quarantine. And then we'll test the animal again, as we do the procurement of the organ. Make sure it's all straight. Dr. Sanjay Gupta 00:13:38 That's the sort of testing that was done on the pig kidney transplanted into Tijuana. And also on Raphael, Tim's kidney donor. Tim Andrews 00:13:48 That'll get everybody moving. Dr. Sanjay Gupta 00:13:51 A transplant that Tim is thankful for every day. Dr. Sanjay Gupta 00:13:56 Every Wednesday, he signs into this Zoom meeting from his kitchen table in New Hampshire. Dr. Sanjay Gupta 00:14:04 Hundreds of people from all over the country want to talk to him about his transplant. Dr. Sanjay Gupta 00:14:09 And that strikes me that you've done all this, but then you also take the time to do these calls. Tim Andrews 00:14:14 That was my promise. Give me this and I will spend the remainder of my life helping people get hope. Dr. Sanjay Gupta 00:14:26 It is the unspoken promise of pioneers. Pay it forward. Towana Looney 00:14:31 I want you to look at me. If I can do it, the next person can do it. Dr. Sanjay Gupta 00:14:41 Towana was the star at a recent medical conference, the Lake Nona Impact Forum. David Ayeres 00:14:46 The system will never be able to deliver enough organs. This is the promise for the future. And thank you for making that future happen. Towana Looney 00:14:58 You're welcome, thank you. Dr. Sanjay Gupta 00:15:00 'Mm-hmm. I was there and I can tell you the audience loved her. You look really good. You feel as good as you look? Towana Looney 00:15:10 Yeah, I do. Denyce Graves 00:15:11 My husband said, how do you feel about all this attention? She said, I love it. Towana Looney 00:15:17 I want the word to get out. Dr. Sanjay Gupta 00:15:21 But the thing about firsts, about pioneers, is that at any moment, their lives can be suddenly thrown into jeopardy. Tim Andrews 00:15:30 I woke up one morning and I was hurting so bad I couldn't walk or anything. And sure enough I had an infection. You can see the remains of it there. Dr. Sanjay Gupta 00:15:44 Tim was hospitalized for three weeks to treat the infection and prevent his kidney from being rejected. Dr. Leonardo Riella 00:15:50 It was a quite hard few days for him and for us as well, but fortunately we were able to overcome and we're in a better spot now. We hope this kidney continues for a long time. Dr. Sanjay Gupta 00:16:03 Turns out as Tim won his fight to keep his kidney, Towana lost hers. Like Tim, Tawanna got an infection, but she also started to reject her pig kidney. So in April, doctors had to remove it. Towona is back on dialysis. It had been 130 days. At the time, she was the longest survivor with a xenotransplant in history. But now soon, that distinction could belong to Tim. Tim Andrews 00:16:35 I don't want people to look at that and say, well, that's it, it didn't work. It worked. It just wasn't perfected yet. We're gonna have to get there Dr. Sanjay Gupta 00:16:49 Science is like life. There are successes and there are failures, but you learn from both of them. Dr. Robert Mongtomery 00:16:57 We stand on the shoulders of giants for sure. It's extraordinary when you think about it. It took a lot of people doing their part to make this happen. Dr. Leonardo Riella 00:17:09 I think patients like Tim will be remembered as heroes. Tim Andrews 00:17:15 What this pig kidney has given me is freedom from this. And what I hope it gives you is hope. Don't give up. I see way too many people give up. Don't give up. Dr. Sanjay Gupta 00:17:34 Tim's future looks bright, and so does the future of this area of medicine. When do you think this might be available to the average persom? Dr. Robert Mongtomery 00:17:45 I think less than five years. Dr. Sanjay Gupta 00:17:51 Do you imagine the future now? Tim Andrews 00:17:53 Yeah, I do. Dr. Sanjay Gupta 00:17:55 Visiting grandkids. Tim Andrews 00:17:56 Visiting grandkids is going to be so much fun, you know, because they saw me at the lowest and now they'll be able to see me alive and laughing and carrying on like Grandpa does. Dr. Sanjay Gupta 00:18:11 That's great. Tim Andrews 00:18:12 It's gonna be awesome. Dr. Sanjay Gupta 00:18:16 On June 5, Tim Andrews became the longest living human with a pig kidney transplant. It's even given him the chance to fulfill a lifelong dream. Tim Andrews 00:18:26 Well, I knew it was about that ball was going to go. Ha ha ha ha! Dr. Sanjay Gupta 00:18:30 Which was throwing out the first pitch for his favorite team, the Boston Red Sox. And more importantly, finally getting to see his grandkids again. Tim Andrews, we all wish you well. Dr. Sanjay Gupta reports Animal Farm is now available to stream on HBO Max. We'll be back next week with a new episode of Chasing Life. Thanks for listening.

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