New Data Show Delve Bio's Metagenomic Platform Accurately Identifies Viruses and Their Subtypes With a Single Test
BOSTON--(BUSINESS WIRE)--May 7, 2025--
Delve Bio, a pioneer in metagenomic next-generation sequencing (mNGS) for infectious diseases, today announced data showing that its groundbreaking infectious disease test, Delve Detect, is also capable of viral subtyping for select pathogens from sequence data analyzed through its proprietary bioinformatics pipeline, Delve Decide. The data will be presented at the Pan American Society for Clinical Virology (PASCV) Annual Meeting on May 8, 2025, in Clearwater, Florida.
'Identifying a pathogen is only the first part of the story. Knowing detailed information about the virus can signal to a physician whether a patient's infection is linked to an outbreak, carries unusual risks, or requires a change in management – crucial information when treating a patient with serious infections,' said Brian O'Donovan, Ph.D., head of bioinformatics at Delve Bio. 'Our study demonstrates mNGS has the potential to provide this information as part of routine testing, eliminating the need for sequential testing and subtyping that may delay patient care.'
In the study, sequencing data generated by Delve Detect were compared to a specialized database of reference genomes. The study determined viral subtypes and phylogenetic classifications delivered by the Delve Decide bioinformatics platform across a number of viruses, including St. Louis encephalitis virus, enterovirus, West Nile virus, varicella-zoster virus and HIV, and described concordance with independent testing methods.
'Metagenomics is a game-changer for diagnosing infectious diseases, delivering meaningful, detailed information about the cause of a patient's infection through a single, straightforward test,' added Steve Miller, M.D., Ph.D., chief medical officer at Delve Bio. 'This study demonstrates that Delve Detect can deliver information that can impact management based on viral subtyping information and improve patient care.'
The data will be presented at the meeting in poster No. 31, Rapid, Simultaneous Viral Pathogen Detection, Subtyping and Strain Differentiation Through Unbiased Metagenomic Sequencing With Delve Detect CSF on May 8 at 2:45 p.m. The study is part of the company's overall presence at the meeting, which also includes a presentation titled Metagenomic Next Generation Sequencing for CNS Infection by Delve co-founder Charles Chiu, M.D., Ph.D., professor of laboratory medicine and medicine/infectious diseases at University of California San Francisco (UCSF) today, Wednesday, May 7, at 6 p.m. Delve Detect was built on technology developed at UCSF, which is exclusively licensed to Delve Bio.
Delve Detect is Delve Bio's flagship metagenomic testing service, providing comprehensive pathogen detection with a 48-hour turnaround time after sample receipt and including access to Delve's Clinical Microbial Sequencing Board, an on-call team of infectious disease experts who review results in clinical context.
About Delve Bio, Inc.
Delve Bio is a metagenomic next-generation sequencing (mNGS) company that empowers laboratories and clinicians with the insights they need to confidently diagnose routine and rare infectious diseases, thereby minimizing the impact of harmful pathogens on humanity. By leveraging its unbiased, pathogen-agnostic mNGS platform, Delve Bio is able to identify a wide range of pathogens with a single test. Founded by world leaders in genomics and infectious disease Drs. Charles Chiu, Joe DeRisi, Michael Wilson, Pardis Sabeti, and Matthew Meyerson, the company is backed by top institutional investors including Perceptive Xontogeny Venture Fund II, Section 32, and GV, along with leading individual investors. For more information, visit www.delve.bio.
View source version on businesswire.com:https://www.businesswire.com/news/home/20250507554197/en/
CONTACT: Company ContactAmy Wong
Senior Director of Marketing and Business Development, Delve Bio
Email:[email protected] ContactJulie McKeough
42 North for Delve Bio
Email:[email protected]
KEYWORD: UNITED STATES NORTH AMERICA FLORIDA MASSACHUSETTS
INDUSTRY KEYWORD: AIDS HEALTH INFECTIOUS DISEASES GENETICS HEALTH TECHNOLOGY BIOTECHNOLOGY
SOURCE: Delve Bio, Inc.
Copyright Business Wire 2025.
PUB: 05/07/2025 07:32 AM/DISC: 05/07/2025 07:31 AM
http://www.businesswire.com/news/home/20250507554197/en
Hashtags
Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles
Fox News
5 hours ago
- Fox News
Medical professionals say schools have gotten too political, citing ‘unscientific modes of thinking'
Two medical professionals argued in a new report that "medical school has gotten too political," citing "unscientific modes of thinking." "Medical students are now immersed in the notion that undertaking political advocacy is as important as learning gross anatomy, physiology, and pharmacology," the authors wrote in The Chronicle of Higher Education. Sally Satel, a lecturer in psychiatry at Yale University School of Medicine, and Thomas S. Huddle, a professor at the University of Alabama at Birmingham's Heersink School of Medicine, cited several instances of political sentiments affecting the medical school industry. They noted that researchers are "promoting unscientific modes of thinking about group-based disparities in health access and status." "The University of Minnesota's Center for Antiracism Research for Health Equity decrees 'structural racism as a fundamental cause of health inequities,' despite the fact that this is at best an arguable thesis, not a fact. (The center was shut down last month.) The Kaiser Family Foundation states that health differentials 'stem from broader social and economic inequities,'" the authors write. Satel and Huddle pushed further by detailing an incident that occurred at the University of California, San Francisco, Medical Center. The institution not only called for a ceasefire in the Gaza war between Israel and Hamas, the authors wrote that staff chanted "intifada, intifada, long live intifada!" which "echoed into patients' rooms." The New York Times reported last summer that the protesters at the University of California, San Francisco, chanting "intifada" consisted of medical students and doctors. Such an incident lays out more deeply the consequences of medical schools prioritizing politics over instruction on professional imperatives, according to the authors. "These doctors were not putting patients first — if anything, they were offending and intimidating patients. They were putting their notion of social justice first," they wrote. The two medical professionals cite other instances where medical schools are steeped in politics, such as endorsing "racial reparations" and instituting "antiracism" training in order to qualify for a medical license in the wake of George Floyd's death. Satel and Huddle offer medical professionals "guidelines" for how to "responsibly" meet patients' needs while leveraging their "professional standing to effect change", including advocating for policies that "directly help patients and are rooted in professional expertise while ensuring that their advocacy does not interfere with their relationships with their colleagues, students, and patients." Satel, a practicing psychiatrist, told Fox News Digital that she is the medical director of a methadone clinic that represents a clinical setting. In response to Fox News Digital's request for comment, Huddle said that his "academic career has been as a clinician teaching how to care for patients while caring for them."
Yahoo
6 hours ago
- Yahoo
2 Michigan residents with measles exposed others to virus in Kent, Oakland counties
Two new measles cases were reported in Michigan on the evening of June 6 — one in an Allegan County resident who exposed others to the highly contagious virus at three sites in Kent County from June 2-4, and a Macomb County resident who exposed others June 3 at a medical office building in Rochester Hills. Because measles can remain infectious in the air for up to two hours after an infected person leaves the room, the Allegan County Health Department said anyone who was at the following locations at these dates and times may have been exposed: Coachmen Strength & Conditioning, 7780 Clyde Park Ave. SW, Byron Center: 6:30-9:30 p.m. June 2. University of Michigan Health West, 5900 Byron Center Ave. SW, Wyoming: 2:18-5:02 a.m. June 4. University of Michigan Health West, Southwest Health Center, 2215 44th St. SW, Wyoming: 11:46 a.m. to 3:45 p.m. June 4. The Macomb County resident exposed others to measles 8 a.m.-7:30 p.m. June 3 at a medical office building at 3950 S. Rochester Road in Rochester Hills, according to the Oakland County Health Division. Several business list 3950 S. Rochester Road as their address. Among them are: Henry Ford Reproductive Medicine — Rochester Hills Michigan Rheumatology and Wellness Center Superior Oral & Maxillofacial Surgery Oakland-Macomb Cancer Specialists Integrative Family Care Zetu Periodontics Abaris Behavioral Health Oakland County spokesperson Bill Mullan said anyone who visited any of the offices within the building during the exposure times on June 3 should "err on the side of caution" and consider themselves exposed. State and county health leaders say anyone who may have been exposed to measles should monitor for symptoms for 21 days. If they develop symptoms, call ahead before seeking medical attention to avoid exposing others. For people who were exposed and are at high-risk for severe illness from a measles infection, immune globulin (IG) treatment may be an option. However, it is effective in preventing or reducing severe disease only if it is given within the first six days after exposure to the virus. Call your medical provider, pharmacy or the county health department if you believe you were exposed and might be eligible for IG treatment. The Allegan County Health Department can be reached 8 a.m.-5 p.m. Mondays through Fridays at 269-673-5411. If it is after office hours, Kent County residents also can call 2-1-1. The Oakland County Health Division's Nurse on Call can be reached 8:30 a.m.-5 p.m. Mondays through Fridays at 800-848-5533 or by email at noc@ People considered high-risk for servere disease from measles include those who are pregnant, unvaccinated children under age 5 and people who have a weakened immune systems because of such underlying conditions as diabetes, HIV, malnutrition and/or because they take immune-suppressing medications. According to the U.S. Centers for Disease Control and Prevention, measles symptoms typically start within 7-14 days after exposure, but also have been known to appear as long as 21 days post exposure and can include: Fever, which may rise above 104 degrees. Respiratory symptoms such as runny nose, cough. Red, watery eyes that can develop into pink eye or conjunctivitis. Two to three days after symptoms begin, tiny white spots, known as Koplik spots, may develop on the inner cheeks, gums and roof of the mouth. Three to five days after symptoms begin, a rash that is red, raised and blotchy appears. It usually begins on the face and spreads to trunk, arms and legs. Measles can cause serious illness, long-term disability and death in people of all ages. As of June 5, the CDC confirmed 1,168 measles cases in 33 states in 2025. Of them, 137 people — 12% of those infected this year — have been hospitalized, and three people have died. In Michigan this year, there have been 12 confirmed cases of measles in the following counties: Allegan, Oakland, Macomb, Kent, Montcalm, Ingham and Marquette. More: What are the symptoms of measles? And other answers to common questions. More: Born between 1957-1989? You may not be protected from measles outbreak The best way to avoid measles infection is to get vaccinated, health officials say. About 95% of the people who've had confirmed measles cases in the U.S. this year were either unvaccinated or thier vaccination status was unknown, the CDC reported. One dose of the measles, mumps rubella (MMR) vaccine provides about 93% protection against the virus, and two doses offer about 97% coverage, the CDC says. It recommends the following for MMR vaccines: A first dose for children at 12 months-15 months old, with a booster dose administered between ages 4 and 6. Anyone born during or after 1957 without evidence of immunity against measles or documentation of having been vaccinated with two doses of MMR vaccine should get vaccinated. People exposed to measles who cannot document immunity against the virus should get post-exposure prophylaxis — a dose of the vaccine to potentially provide protection within 72 hours of initial exposure, or immunoglobulin within six days of exposure. The CDC changed its recommendations in 1989 from one dose of the MMR vaccine to two doses, which provides longer-lasting and more robust protection. People born between 1957 and 1989 who have had just a single dose of the vaccine may be at a higher risk of contracting the virus in an outbreak setting. Many medical providers and pharmacies have it available. In addition, local health departments often can provide the MMR vaccine. In Oakland County: Health division immunization clinic hours are 8:30 a.m.-5 p.m. Mondays, Wednesdays and Fridays; 9:30 a.m.-6 p.m. Tuesdays, and 7:30 a.m.-5 p.m. Thursdays at the following locations: North Oakland Health Center, 1200 N. Telegraph Road, Building 34 East, Pontiac South Oakland Health Center, 27725 Greenfield Road, Southfield In Allegan County: Call 269-673-5411 for guidance and details about health department vaccinations. Contact Kristen Shamus: kshamus@ Subscribe to the Free Press. This article originally appeared on Detroit Free Press: Michiganders exposed others to measles in Oakland, Kent counties
Yahoo
15 hours ago
- Yahoo
Oakland County issues alert for measles exposure site in Rochester Hills
FOX 2 - The Oakland County Health Division is notifying the public about a Rochester Hills measles exposure site involving a person from another county. The exposure site is a medical office building at 3950 S. Rochester Road at the corner of South Boulevard on Tuesday, June 3, according to a release from the Oakland County Health Division. Anyone there between 8 a.m. and 7:30 p.m. may have been exposed to measles. If you think you were exposed to measles at this location on June 3, Immune Globulin (IG) treatment is effective within six days of exposure for high-risk individuals. Those considered high-risk include women who are pregnant, unvaccinated children under age 5 and those who have a weakened immune system due to illness and disease including diabetes or HIV, malnutrition and/or medications. If you are not eligible for IG, monitor symptoms through June 24. If symptoms develop, call ahead to your health care provider. Individuals born in or before 1957 are considered immune. Measles is a highly contagious, vaccine-preventable disease that is spread by direct person-to-person contact and through the air. The Health Division recommends unvaccinated individuals ages 1 year and older receive a measles vaccination to protect themselves and those around them. Anyone who doesn't have a record of two MMR vaccines, unsure if they've have been vaccinated, or unsure if you've had measles in the past, needs to contact their health care provider. Measles can live for up to two hours in the air where an infected person coughed or sneezed. Symptoms of measles usually begin 7-14 days after exposure, but can appear up to 21 days after exposure, and may include: High fever (may spike to over 104°F Cough Runny nose Red, watery eyes (conjunctivitis) Tiny white spots on the inner cheeks, gums and roof of mouth (Koplik Spots) 2-3 days after symptoms begin. A rash that is red, raised, blotchy; usually starts on face, spreads to trunk, arms and legs 3-5 days after symptoms begin. The MMR vaccine is available through some health care providers, Oakland County Health Division offices in Southfield and Pontiac, and many pharmacies. Health Division offices are located at the following addresses: North Oakland Health Center, 1200 N. Telegraph Road, Building 34 East, Pontiac South Oakland Health Center, 27725 Greenfield Road, Southfield. Health Division clinics hours are Monday, Wednesday and Friday 8:30 a.m. – 5 p.m. Tuesday 9:30 a.m. – 6 p.m. and Thursday 7:30 a.m. – 5 p.m. Visit for more information on measles, or contact Nurse on Call, 8:30 a.m. to 5 p.m. Monday through Friday, at 800-848-5533 or noc@
