
My sober assessment of the fat jabs
He explained he was on Mounjaro, the slimming drug, and one of its side effects was to suppress his desire for alcohol. He'd had a couple of glasses earlier in the evening, but had then lost interest. 'You should try it,' he said, eyeing my unsteady gait.
After a particularly heavy night a few weeks ago, I decided to follow his advice. He'd given me the name of a website that could prescribe Mounjaro following an online consultation, but when I entered my details it told me I was ineligible. Not fat enough, apparently. I was initially quite flattered, but then realised that couldn't possibly be true. I weighed myself and, sure enough, I'd understated my weight on the application form by 10lb. I found a second website offering the same service, entered my correct weight and, bingo, the wonder drug arrived 24 hours later.
I felt a bit squeamish about injecting myself, but the needle is so tiny you can barely feel it. Would it have any effect? I was dubious because the initial dose is only 2.5mg, which you're supposed to give yourself once a week for a month before upping it to 5mg. And I was right to be sceptical because it didn't do much to curb my appetite for food. Would it help me moderate my drinking? I went to a posh dinner that night where the host was serving good mature claret – my first test.
To begin with, I noticed no change. It tasted as good as it always does and after I'd polished off the first glass I signalled for the waiter to refill it. But then something odd happened. Instead of that familiar warm glow, I began to feel slightly dizzy. It could just be because I'm drinking on an empty stomach, I thought, and got stuck into the second glass. Still no euphoric effect. On the contrary, the dizziness increased, accompanied by a mild headache. It was as if my dopamine receptors were malfunctioning and sending a negative signal to my brain rather than a positive one. It was like licking a battery instead of using it to generate heat. For the first time in about 40 years, I stopped drinking after the second glass.
OK, so the drug passed its initial trial. But that was a dinner. Would it be strong enough to stop me drinking at a party? Last week came the ultimate challenge – The Spectator summer party. Would I be able to stagger out at 10.30 p.m. without being supported on either side by a couple of interns? (The magazine hires an army of interns every summer whose only job is to put the writers in taxis after the annual shindig.)
I decided to pace myself by drinking white wine spritzers and that seemed to do the trick. I got through two without any discernible effect, neither a pleasant buzz nor a feeling of vertigo. I ploughed on, more interested in observing my experiment than talking to the big hitters around me. After the third spritzer the dizziness returned, and after a fourth so did the headache. I didn't feel drunk so much as disorientated. Instead of getting another, I just decided to keep diluting what remained in my glass with soda water until, by 10.30 p.m., that's all I was drinking.
Being sober at the end of the Spectator summer party was a novel sensation. I felt like a first responder surveying the aftermath of a natural disaster. Bodies lay sprawled in hedges; young women clutched on to each other, make-up smudged and hair in disarray, as they stumbled towards the exit; Rod Liddle howled like a mastodon bellowing across a primeval swamp. Was it always like this, I wondered? I felt a tinge of regret, as if I'd missed all the fun. Then again, how much fun is it if you can recall nothing the following morning? If no one can remember a pack of shadow cabinet ministers baying for broken glass, did they really make a sound?
The next morning I felt quite smug. I must have been the only person in the Westminster village not to have a hangover. Yes, the sober life isn't very exciting, but at least you don't live in dread of a colleague gleefully informing you of something incredibly embarrassing you did the night before. Now that I'm 61 and a peer of the realm, that's probably a bargain I should accept. Mounjaro, you are my Man Friday. And to cap it all, when the dosage goes up I might even lose a little weight.

Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles

South Wales Argus
16 hours ago
- South Wales Argus
Newport pays final respects to Dr Graeme Yule at funeral
The death of the much-loved GP, who served at St Julians Medical Centre for more than 30 years, left patients and colleagues stunned. By 1pm the pavements along Durham Road had filled with mourners seeking shade, while the junction with Stafford Road overflowed with those waiting to witness the cortege. Emotion filled the streets, with many quietly crying as they stood shoulder to shoulder with fellow mourners. The Union Flag of the St Julian's Conservative Club flew at half-mast, fluttering above the emotional scene. The hearse carrying Dr Yule stopped outside the medical centre, which is now synonymous with the good doctor to allow the community to pay its respect. Mourners queued behind the hearse to put one hand on the coffin, as a final gesture to a treasured servant of the community. As the vehicle climbed Stafford Road, one voice rang out above the hush: 'Three cheers for Dr Yule.' The crowd responded and then applause followed as the hearse slowly took Dr Yule to his final appointment. Dr Graeme Yule of St Julians Medical Centre (Image: Facebook image of St Julians Medical Centre) Among those gathered to pay last respects were patients whose lives had been shaped by the doctor's care. Alex Harris said, 'He was an amazing guy. He could help you with darker things that others ignored. He just had a way to communicate with you. Even the way he would sit in his chair as he listened helped bring out your troubles to him. He sat there relaxed, and it made you relaxed.' Alex smiled sadly as he recalled how Dr Yule never forgot personal details, made Alex understand himself better and often asked after family members. 'One in a million,' he added. Sharon Prowse, a military veteran, shared similar memories. 'When I left the army, he treated me, and I can't express how grateful I am to him. His understanding of my needs was incredible.' She and Alex both warmly demonstrated the quiet authority of the doctor's signature seated style—leaning back, open and composed, a posture that made patients feel truly heard and put them at their ease. Newport said farewell today not just to a physician, but to a comforter and a friend.


The Sun
2 days ago
- The Sun
I can't go to work & am scared to move from the loo because of Mounjaro… but people say it's down to WHERE I'm injecting
A MOUNJARO user has claimed that after 19 weeks of injecting, she is 'too scared to move away from the toilet' as a result of her side effects. Maddy, who has lost 40lbs [2 stone 8lbs] since using the weight loss jabs, is now unable to go to work as a result of suffering from diarrhoea. 3 3 Posting on social media, the content creator got candid on her Mounjaro side effects, leaving many open-mouthed. As she stood in her bathroom, she confirmed that after injecting herself with Mounjaro, which is known as the King Kong of jabs, in her arm, she was very 'poorly.' Not only did she feel sick, but she also had diarrhoea and sulphur burps too. Despite this, Maddy confirmed that last Tuesday, she decided to inject in her arm again. But by Wednesday afternoon, she noticed the re-emergence of sulphur burps - which have been described by many as foul-tasting burps that taste like eggs. And that wasn't all, as Maddy continued: 'And I know what comes hand-in-hand with sulphur burps - it's the s***s.' So it didn't come as a surprise when Maddy woke up the following morning with an upset stomach, as she admitted: 'I felt rough, but not too bad - I still went to work and then towards the end of the day at work, I felt like s**t, I literally went and slept in my car for half an hour because I just felt rough.' Upon returning home from work, Maddy then slept from 5:30pm until 11pm. After waking up, the brunette beauty had some dinner and went back to bed, but it wasn't long before more side effects started, as she confessed: 'My belly felt so bubbly and gassy…Woke up two or three times in the night with the s***s and I actually did s**t myself. 'If you're on Mounjaro, then you know, if you're not, you won't understand, so after that I thought, I'm not going to work today, I'm not even going to risk it. It's not worth it at work.' Sun Health Explainer: Fat jabs Not only this, but she also revealed: 'I've been too scared to move away from the toilet all morning because I still feel like s**t.' The TikTok clip, which was posted under the username @ mjwithmad, has clearly left many open-mouthed, as it has quickly racked up 56,100 views, 892 likes and 118 comments. But Maddy isn't the only Mounjaro user to be experiencing such horrendous side effects, as many others flocked to the comments to share their similar experiences. One person said: 'These sulphur burps are something else! I'm week three and I jabbed my arm yesterday. I feel dreadful!' Another added: 'Did my first injection in my belly last week was fine, did my arm yesterday and today I feel so tired and sluggish, lost half a stone in a week though!' A third commented: 'Not me seeing this video one day after I decided to jab in my arm for the first time. Now I'm scared.' Whilst one woman claimed: 'Girl, this is so so common on Mounjaro!! More common than I'd like to admit.' Meanwhile, someone else wrote: 'I was looking forward to trying my arm but now I'm not so sure.' Everything you need to know about fat jabs Weight loss jabs are all the rage as studies and patient stories reveal they help people shed flab at almost unbelievable rates, as well as appearing to reduce the risk of serious diseases. Wegovy – a modified version of type 2 diabetes drug Ozempic – and Mounjaro are the leading weight loss injections used in the UK. Wegovy, real name semaglutide, has been used on the NHS for years while Mounjaro (tirzepatide) is a newer and more powerful addition to the market. Mounjaro accounts for most private prescriptions for weight loss and is set to join Wegovy as an NHS staple this year. How do they work? The jabs work by suppressing your appetite, making you eat less so your body burns fat for energy instead and you lose weight. They do this my mimicking a hormone called GLP-1, which signals to the brain when the stomach is full, so the drugs are officially called GLP-1 receptor agonists. They slow down digestion and increase insulin production, lowering blood sugar, which is why they were first developed to treat type 2 diabetes in which patients' sugar levels are too high. Can I get them? NHS prescriptions of weight loss drugs, mainly Wegovy and an older version called Saxenda (chemical name liraglutide), are controlled through specialist weight loss clinics. Typically a patient will have to have a body mass index (BMI) of 30 or higher, classifying them as medically obese, and also have a weight-related health condition such as high blood pressure. GPs generally do not prescribe the drugs for weight loss. Private prescribers offer the jabs, most commonly Mounjaro, to anyone who is obese (BMI of 30+) or overweight (BMI 25-30) with a weight-related health risk. Private pharmacies have been rapped for handing them out too easily and video calls or face-to-face appointments are now mandatory to check a patient is being truthful about their size and health. Are there any risks? Yes – side effects are common but most are relatively mild. Around half of people taking the drug experience gut issues, including sickness, bloating, acid reflux, constipation and diarrhoea. Dr Sarah Jarvis, GP and clinical consultant at said: 'One of the more uncommon side effects is severe acute pancreatitis, which is extremely painful and happens to one in 500 people.' Other uncommon side effects include altered taste, kidney problems, allergic reactions, gallbladder problems and hypoglycemia. Evidence has so far been inconclusive about whether the injections are damaging to patients' mental health. Figures obtained by The Sun show that, up to January 2025, 85 patient deaths in the UK were suspected to be linked to the medicines. What do the experts say? After numerous fat jab users complaining of similar side effects following injecting Mounjaro, which is said to suppress the appetite, into their arms, we spoke to the experts to get their thoughts on why this might be happening. Jason Murphy, Head of Pharmacy at Chemist4U told Fabulous: 'Your choice of injection site can affect the side effects that you can experience when taking Mounjaro. 'In a clinical trial, it was revealed that the overall percentage of participants who experienced side effects varied considerably - abdomen: 68.52%, upper arm: 57.41% and thigh: 43.40%.' Not only this, but Roj Helin Parlakyildiz, a Clinician and Clinical Content Lead at Voy, shared: 'While the pharmacokinetics of subcutaneous injections like Mounjaro are generally consistent across approved sites (abdomen, thigh, upper arm), local absorption can still vary slightly based on factors like blood flow, fat distribution, and muscular activity in those areas. This may influence how quickly the medication is absorbed. 'For example, the upper arm may have less subcutaneous fat and more variable injection depth compared to the abdomen or thigh, especially if the injection technique is less controlled, as the upper arm can be an awkward site. 'This might lead to faster absorption, potentially triggering more acute gastrointestinal side effects like sulphur burps or diarrhoea in sensitive individuals.' Meanwhile, Clinical pharmacist Kiran Jones of Oxford Online Pharmacy also said to us: 'While the injection site doesn't theoretically have much influence on side effects experienced, some users consistently report more nausea with stomach injections. What are the other side effects of weight loss jabs? Like any medication, weight loss jabs can have side effects. Common side effects of injections such as Ozempic include: Nausea: This is the most commonly reported side effect, especially when first starting the medication. It often decreases over time as your body adjusts. Vomiting: Can occur, often in conjunction with nausea. Diarrhea: Some people experience gastrointestinal upset. Constipation: Some individuals may also experience constipation. Stomach pain or discomfort: Some people may experience abdominal pain or discomfort. Reduced appetite: This is often a desired effect for people using Ozempic for weight loss. Indigestion: Can cause a feeling of bloating or discomfort after eating. Serious side effects can also include: Pancreatitis: In rare cases, Ozempic may increase the risk of inflammation of the pancreas, known as pancreatitis, which can cause severe stomach pain, nausea, and vomiting. Kidney problems: There have been reports of kidney issues, including kidney failure, though this is uncommon. Thyroid tumors: There's a potential increased risk of thyroid cancer, although this risk is based on animal studies. It is not confirmed in humans, but people with a history of thyroid cancer should avoid Ozempic. Vision problems: Rapid changes in blood sugar levels may affect vision, and some people have reported blurry vision when taking Ozempic. Hypoglycemia (low blood sugar): Especially if used with other medications like sulfonylureas or insulin. 'We've heard similar things from our patients, though we think this feedback is due to small individual differences like body fat distribution, blood flow, skin thickness and personal sensitivity. These can all subtly affect how your body responds, even if the absorption is technically the same. 'At the moment, science hasn't quite caught up with this phenomenon. But just because it isn't fully explained doesn't mean it isn't happening.' As a result, this pharmacist stressed the importance of rotating injection sites, as he added: 'If you notice more side effects in one area, try a different site next time. Keep a log of your symptoms and discuss any patterns with your pharmacist or healthcare provider. 'There's no universally 'best' site to inject - just the one that works best for you.'


Scottish Sun
2 days ago
- Scottish Sun
I can't go to work & am scared to move from the loo because of Mounjaro… but people say it's down to WHERE I'm injecting
Click to share on X/Twitter (Opens in new window) Click to share on Facebook (Opens in new window) A MOUNJARO user has claimed that after 19 weeks of injecting, she is 'too scared to move away from the toilet' as a result of her side effects. Maddy, who has lost 40lbs [2 stone 8lbs] since using the weight loss jabs, is now unable to go to work as a result of suffering from diarrhoea. 3 A young woman has revealed that she has been unable to go to work and is "too scared" to leave her toilet, after suffering severe side effects on Mounjaro Credit: tiktok/@mjwithmad 3 Maddy has lost over two stone since using the fat jabs, but has been experiencing sickness, diarrhoea and sulphur burps Credit: tiktok/@mjwithmad 3 Mounjaro is typically used to treat type 2 diabetes Credit: Getty Posting on social media, the content creator got candid on her Mounjaro side effects, leaving many open-mouthed. As she stood in her bathroom, she confirmed that after injecting herself with Mounjaro, which is known as the King Kong of jabs, in her arm, she was very 'poorly.' Not only did she feel sick, but she also had diarrhoea and sulphur burps too. Despite this, Maddy confirmed that last Tuesday, she decided to inject in her arm again. But by Wednesday afternoon, she noticed the re-emergence of sulphur burps - which have been described by many as foul-tasting burps that taste like eggs. And that wasn't all, as Maddy continued: 'And I know what comes hand-in-hand with sulphur burps - it's the s***s.' So it didn't come as a surprise when Maddy woke up the following morning with an upset stomach, as she admitted: 'I felt rough, but not too bad - I still went to work and then towards the end of the day at work, I felt like s**t, I literally went and slept in my car for half an hour because I just felt rough.' Upon returning home from work, Maddy then slept from 5:30pm until 11pm. After waking up, the brunette beauty had some dinner and went back to bed, but it wasn't long before more side effects started, as she confessed: 'My belly felt so bubbly and gassy…Woke up two or three times in the night with the s***s and I actually did s**t myself. 'If you're on Mounjaro, then you know, if you're not, you won't understand, so after that I thought, I'm not going to work today, I'm not even going to risk it. It's not worth it at work.' Sun Health Explainer: Fat jabs Not only this, but she also revealed: 'I've been too scared to move away from the toilet all morning because I still feel like s**t.' The TikTok clip, which was posted under the username @mjwithmad, has clearly left many open-mouthed, as it has quickly racked up 56,100 views, 892 likes and 118 comments. My belly felt so bubbly and gassy Maddy But Maddy isn't the only Mounjaro user to be experiencing such horrendous side effects, as many others flocked to the comments to share their similar experiences. One person said: 'These sulphur burps are something else! I'm week three and I jabbed my arm yesterday. I feel dreadful!' Another added: 'Did my first injection in my belly last week was fine, did my arm yesterday and today I feel so tired and sluggish, lost half a stone in a week though!' A third commented: 'Not me seeing this video one day after I decided to jab in my arm for the first time. Now I'm scared.' Your choice of injection site can affect the side effects that you can experience when taking Mounjaro Jason Murphy Whilst one woman claimed: 'Girl, this is so so common on Mounjaro!! More common than I'd like to admit.' Meanwhile, someone else wrote: 'I was looking forward to trying my arm but now I'm not so sure.' Everything you need to know about fat jabs Weight loss jabs are all the rage as studies and patient stories reveal they help people shed flab at almost unbelievable rates, as well as appearing to reduce the risk of serious diseases. Wegovy – a modified version of type 2 diabetes drug Ozempic – and Mounjaro are the leading weight loss injections used in the UK. Wegovy, real name semaglutide, has been used on the NHS for years while Mounjaro (tirzepatide) is a newer and more powerful addition to the market. Mounjaro accounts for most private prescriptions for weight loss and is set to join Wegovy as an NHS staple this year. How do they work? The jabs work by suppressing your appetite, making you eat less so your body burns fat for energy instead and you lose weight. They do this my mimicking a hormone called GLP-1, which signals to the brain when the stomach is full, so the drugs are officially called GLP-1 receptor agonists. They slow down digestion and increase insulin production, lowering blood sugar, which is why they were first developed to treat type 2 diabetes in which patients' sugar levels are too high. Can I get them? NHS prescriptions of weight loss drugs, mainly Wegovy and an older version called Saxenda (chemical name liraglutide), are controlled through specialist weight loss clinics. Typically a patient will have to have a body mass index (BMI) of 30 or higher, classifying them as medically obese, and also have a weight-related health condition such as high blood pressure. GPs generally do not prescribe the drugs for weight loss. Private prescribers offer the jabs, most commonly Mounjaro, to anyone who is obese (BMI of 30+) or overweight (BMI 25-30) with a weight-related health risk. Private pharmacies have been rapped for handing them out too easily and video calls or face-to-face appointments are now mandatory to check a patient is being truthful about their size and health. Are there any risks? Yes – side effects are common but most are relatively mild. Around half of people taking the drug experience gut issues, including sickness, bloating, acid reflux, constipation and diarrhoea. Dr Sarah Jarvis, GP and clinical consultant at said: 'One of the more uncommon side effects is severe acute pancreatitis, which is extremely painful and happens to one in 500 people.' Other uncommon side effects include altered taste, kidney problems, allergic reactions, gallbladder problems and hypoglycemia. Evidence has so far been inconclusive about whether the injections are damaging to patients' mental health. Figures obtained by The Sun show that, up to January 2025, 85 patient deaths in the UK were suspected to be linked to the medicines. What do the experts say? After numerous fat jab users complaining of similar side effects following injecting Mounjaro, which is said to suppress the appetite, into their arms, we spoke to the experts to get their thoughts on why this might be happening. Jason Murphy, Head of Pharmacy at Chemist4U told Fabulous: 'Your choice of injection site can affect the side effects that you can experience when taking Mounjaro. 'In a clinical trial, it was revealed that the overall percentage of participants who experienced side effects varied considerably - abdomen: 68.52%, upper arm: 57.41% and thigh: 43.40%.' There's no universally 'best' site to inject - just the one that works best for you Kiran Jones Not only this, but Roj Helin Parlakyildiz, a Clinician and Clinical Content Lead at Voy, shared: 'While the pharmacokinetics of subcutaneous injections like Mounjaro are generally consistent across approved sites (abdomen, thigh, upper arm), local absorption can still vary slightly based on factors like blood flow, fat distribution, and muscular activity in those areas. This may influence how quickly the medication is absorbed. 'For example, the upper arm may have less subcutaneous fat and more variable injection depth compared to the abdomen or thigh, especially if the injection technique is less controlled, as the upper arm can be an awkward site. 'This might lead to faster absorption, potentially triggering more acute gastrointestinal side effects like sulphur burps or diarrhoea in sensitive individuals.' Meanwhile, Clinical pharmacist Kiran Jones of Oxford Online Pharmacy also said to us: 'While the injection site doesn't theoretically have much influence on side effects experienced, some users consistently report more nausea with stomach injections. What are the other side effects of weight loss jabs? Like any medication, weight loss jabs can have side effects. Common side effects of injections such as Ozempic include: Nausea: This is the most commonly reported side effect, especially when first starting the medication. It often decreases over time as your body adjusts. Vomiting: Can occur, often in conjunction with nausea. Diarrhea: Some people experience gastrointestinal upset. Constipation: Some individuals may also experience constipation. Stomach pain or discomfort: Some people may experience abdominal pain or discomfort. Reduced appetite: This is often a desired effect for people using Ozempic for weight loss. Indigestion: Can cause a feeling of bloating or discomfort after eating. Serious side effects can also include: Pancreatitis: In rare cases, Ozempic may increase the risk of inflammation of the pancreas, known as pancreatitis, which can cause severe stomach pain, nausea, and vomiting. Kidney problems: There have been reports of kidney issues, including kidney failure, though this is uncommon. Thyroid tumors: There's a potential increased risk of thyroid cancer, although this risk is based on animal studies. It is not confirmed in humans, but people with a history of thyroid cancer should avoid Ozempic. Vision problems: Rapid changes in blood sugar levels may affect vision, and some people have reported blurry vision when taking Ozempic. Hypoglycemia (low blood sugar): Especially if used with other medications like sulfonylureas or insulin. 'We've heard similar things from our patients, though we think this feedback is due to small individual differences like body fat distribution, blood flow, skin thickness and personal sensitivity. These can all subtly affect how your body responds, even if the absorption is technically the same. 'At the moment, science hasn't quite caught up with this phenomenon. But just because it isn't fully explained doesn't mean it isn't happening.' As a result, this pharmacist stressed the importance of rotating injection sites, as he added: 'If you notice more side effects in one area, try a different site next time. Keep a log of your symptoms and discuss any patterns with your pharmacist or healthcare provider. 'There's no universally 'best' site to inject - just the one that works best for you.' Unlock even more award-winning articles as The Sun launches brand new membership programme - Sun Club