logo
Hospital superbug ‘eating' medical plastics, devices & implants: Study

Hospital superbug ‘eating' medical plastics, devices & implants: Study

Time of India18-05-2025

Representative photo
NEW DELHI:
Pseudomonas aeruginosa
, a bacteria known for causing 10%-30% of
hospital-acquired infections
in India, has been shown to break down plastic used in sutures, stents, wound dressings and implants. The 'world-first discovery' published in the journal Cell Reports challenges the widely held belief that pathogens cannot degrade medical plastics.
It also means any medical device or treatment that contains plastic could be susceptible to degradation by bacteria, the study said.
Professor Ronan McCarthy, who led the study, said, 'It means we need to reconsider how pathogens exist in the hospital environment.' Plastics, including plastic surfaces, could potentially be food for these bacteria. Pathogens with this ability could survive for longer in the hospital environment, he added. McCarthy and his team isolated the enzyme Pap1 from a strain of pseudomonas aeruginosa that was originally sampled from a patient's wound. Tested in a lab, the enzyme degraded 78% of a plastic sample in just seven days. Crucially, the bacteria could also use plastic as its only carbon source — effectively eating it.
Pseudomonas aeruginosa is among a bacteria group responsible for most hospital infections that can resist antibiotics.

Orange background

Try Our AI Features

Explore what Daily8 AI can do for you:

Comments

No comments yet...

Related Articles

Can hospital superbugs chew up stents and implants? Here's what a new study says
Can hospital superbugs chew up stents and implants? Here's what a new study says

Indian Express

time22-05-2025

  • Indian Express

Can hospital superbugs chew up stents and implants? Here's what a new study says

A dangerous hospital-acquired bacteria can digest and live on plastics present in sutures, stents, wound dressings and implants in your body. Researchers from UK's Brunel University also found that when the bacteria used plastics as its food source, it led to the formation of more biofilms — barriers that can protect the pathogen from attacks by the immune system and antibiotics. The finding means that bacteria, such as the one they studied, could degrade medical implants, lead to infections at the site of the implant and cause infections that are harder to treat. What did the researchers find? There are bacteria in the environment that have developed the capacity to break down different types of plastics. So researchers wanted to see whether bacteria that cause infections in humans could also lead to such degradation within the body. For the study, scientists looked for different pathogens with genes that could potentially produce enzymes similar to the ones that environmental bacteria use to degrade plastics. While they found several hits, they selected a Pseudomonas aeruginosa sample that came from a patient's wound. They isolated an enzyme — which they named Pap1— that could digest a type of bio-degradable plastic frequently used in medical devices called polycaprolactone (PCL) plastic. The researchers found that the enzyme degraded 78 per cent of the plastic sample in just seven days. Importantly, the researchers found that the bacteria were not only degrading the plastic, they were also using it as their carbon source — effectively eating it. 'This means we need to reconsider how pathogens exist in the hospital environment. Plastics, including plastic surfaces, could potentially be food for these bacteria. Pathogens with this ability could survive for longer in hospitals,' Dr Ronan McCarthy, author and professor of biomedical sciences at Brunel University, said in a release. Why is this concerning? This is concerning for several reasons: One, bacteria could live on in hospitals or within a patient even when there aren't any other nutrients present. Two, they could degrade medical devices that use plastics, leading to their failure. This could lead to a rethink of materials that should be used for medical devices. Three, researchers found that the plastic-digesting bacteria could cause more severe infections. The researchers further found that the bacteria were using the broken down plastic molecules to create biofilms (a matrix made of sugars, proteins, fats and DNA) that make pathogens more resistant and difficult to treat. Four, degrading medical devices would also mean that the pathogens would be able to create pits and niches within the human body, where it could be shielded from the immune system and antibiotics, again causing difficult-to-treat infections. Are there other pathogens that could have this ability? Researchers found that other pathogens like Streptococcus pneumoniae, Klebsiella pneumoniae and Acinetobacter baumannii, too, carried genes that could potentially create plastic-digesting enzymes. More studies are needed. Importantly, the researchers found that Pap1 enzyme was structurally similar to known enzymes that can degrade even more hardy plastics such as PET bottles.

Hospital superbug ‘eating' medical plastics, devices & implants: Study
Hospital superbug ‘eating' medical plastics, devices & implants: Study

Time of India

time18-05-2025

  • Time of India

Hospital superbug ‘eating' medical plastics, devices & implants: Study

Representative photo NEW DELHI: Pseudomonas aeruginosa , a bacteria known for causing 10%-30% of hospital-acquired infections in India, has been shown to break down plastic used in sutures, stents, wound dressings and implants. The 'world-first discovery' published in the journal Cell Reports challenges the widely held belief that pathogens cannot degrade medical plastics. It also means any medical device or treatment that contains plastic could be susceptible to degradation by bacteria, the study said. Professor Ronan McCarthy, who led the study, said, 'It means we need to reconsider how pathogens exist in the hospital environment.' Plastics, including plastic surfaces, could potentially be food for these bacteria. Pathogens with this ability could survive for longer in the hospital environment, he added. McCarthy and his team isolated the enzyme Pap1 from a strain of pseudomonas aeruginosa that was originally sampled from a patient's wound. Tested in a lab, the enzyme degraded 78% of a plastic sample in just seven days. Crucially, the bacteria could also use plastic as its only carbon source — effectively eating it. Pseudomonas aeruginosa is among a bacteria group responsible for most hospital infections that can resist antibiotics.

Woman Who Didn't Eat Food For First 10 Years Of Her Life, Dies Aged 26
Woman Who Didn't Eat Food For First 10 Years Of Her Life, Dies Aged 26

NDTV

time13-05-2025

  • NDTV

Woman Who Didn't Eat Food For First 10 Years Of Her Life, Dies Aged 26

A British woman who did not eat food for the first decade of her life and was fed through a tube has died at the age of 26, her family announced, as per a report in The Telegraph. Tia-Mae McCarthy's mother, Sue McCarthy, found her unresponsive in her bed on April 28. The cause of her death remains unknown, but more tests are being carried out to ascertain how she died. "There was nothing abnormal. She had a bit of a cough, but was otherwise well," said her brother, Din, 22. "Her mindset was a lot younger than her physical age, so she couldn't live independently or have a job but she had a very full life. She loved horse riding and she was really into her arts and crafts." Ms Mae McCarthy's case baffled scientists across the globe as she received nutrients, vital to the human body's sustenance, through a tube while she slept for the first 10 years of her life. Born 12 weeks premature and weighing just under a kilogram, Tia-Mae had a rare congenital disorder called oesophageal atresia, which affects just one in 40,000 children. Since Tia-Mae's oesophagus and stomach were unconnected, she had to undergo a life-saving operation as a three-month-old toddler, where the two body parts were connected. For the first year of her life, Ms McCarthy recounts, her daughter spent most of the time in hospitals. Doctors baffled Despite having other disabilities, doctors could not pinpoint any medical reason for her refusal to food. Ms McCarthy suspected that it was a psychological problem that stemmed from the early months of her life when Tia stopped breathing multiple times and had to be resuscitated. Her case even featured in a 2006 documentary called The Girl Who Never Ate. As a desperate attempt, her mother took her to a specialist in Austria who ran a controversial research programme, which included periods of controlled starvation. Tia-Mae showed interest in food for the first time when she was 10. The tube keeping her alive was subsequently removed in December 2012, and by the age of 15, she had a normal diet. However, she was never able to live independently due to her disabilities.

DOWNLOAD THE APP

Get Started Now: Download the App

Ready to dive into the world of global news and events? Download our app today from your preferred app store and start exploring.
app-storeplay-store