
Quince Enters the Beauty Marketplace
The Beauty Atelier by Quince opens with an assortment of skincare best-sellers from Augustinus Bader, 111Skin and Irene Forte, with price points between $180 and $305. Shoppers earn 30 percent of their purchases back as Quince store credit.
The Atelier will live as a shop on Quince's website, and opens with a selection of 11 products comprising a selection of each brand's heroes, like Bader's Rich Cream ($305) or 111Skin's Repair Serum ($180), focussed on facial skincare. De Chatellus indicated more categories, brands and products will launch in the coming months. Purchases on The Beauty Atelier are fulfilled by the brands themselves, not Quince.
The company's objective 'is really to be the consumer destination for thoughtfully curated, high quality essentials offered up at the best value,' Daphne de Chatellus, Quince's head of emerging categories, told The Business of Beauty. 'Beauty is one of those essentials.' (The name Quince comes from 'quintessentials.')
The push into skincare is part of Quince's bigger beauty and wellness strategy. In February, the retailer released supplements; in March, it launched fine fragrances. Since its establishment in 2018, Quince has become known not only for its wide assortment of accessible luxuries but also its dupes of pricier products. The company's choice to move into boutique beauty reads as a departure.
'We did explore what it would look like if we launched our own products, and that's not to say we never will,' said Antonieta Moreland, Quince's head of brand. 'But we wanted to be really thoughtful. It helps the consumer to show them that we're partnering with people who really understand the space, which is unique compared to a cashmere sweater or linen bedding.' The Beauty Atelier by Quince will launch with skincare from three brands including Augustinus Bader and Irene Forté, with price points between $180 and $305. (Quince) Marketplace Matters
Quince is the latest retailer of its kind to turn to the marketplace model, a third-party environment where brands can reach shoppers without the fuss of wholesale.
From department stores and big box chains to specialty beauty, nearly all categories of retailers have added online marketplaces to compete with Amazon. Beauty retailers have been the latest to acknowledge the threat after the e-commerce behemoth became the US' biggest beauty retailer last year, overtaking incumbent Walmart.
The free-for-all of the marketplace model means one can reliably find third-party seller listings of classic luxuries like La Mer or new ones from Augustinus Bader on Target or Walmart. While mass retailers were the first to get in on the marketplace model, higher-end stores are increasingly following suit: Nordstrom added a marketplace in 2024, following Macy's in 2022. After losing market share last year, Ulta Beauty will be launching its own marketplace in the fall.
Retailers have recognized the model's scaling advantages, as it gives them the ability to add an unlimited number of brands without having to buy inventory or handle storage and fulfilment. Fashion e-tailers have especially struggled with managing beauty inventory — last year, Net-a-Porter scrapped its beauty wholesaling business in favor of editorial affiliate links fulfilled by the brands themselves.
'There's only so much physical real estate space in our stores,' said Ulta Beauty's chief retail officer Aimee Bayer-Thomas in an interview with Business of Beauty earlier this year, adding that the aim was an 'amplified extension' of the in-store selection.
Of course, a marketplace model also brings about issues of brand equity: Retailers trusted for their curation risk opening themselves up to unknown third-party resellers and counterfeits. Ulta Beauty's marketplace will not be an Amazon-style situation, but rather a closed platform requiring approval from the retailer to sell on it.
'We are going to take great care with our brands and thought around who is invited to participate in the marketplace. It's not just an open marketplace,' said Bayer-Thomas.
The same is true of Quince's curated marketplace, as the DTC e-tailer has sought out marketplace partners for their luxury positioning and significantly higher price points — Augustinus Bader has some products that go for just a fraction of the cost of a clothing piece from the label.
'As we look ahead to the Atelier throughout the year, we plan to expand thoughtfully into premium or prestige price points,' de Chatellus said, as the retailer expands its existing brand selection and launches new categories, including hair and body. 'This is really just the beginning.'
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Business Wire
2 days ago
- Business Wire
Quince Therapeutics Provides Business Update and Reports Second Quarter 2025 Financial Results
SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Quince Therapeutics, Inc. (Nasdaq: QNCX), a late-stage biotechnology company dedicated to unlocking the power of a patient's own biology for the treatment of rare diseases, today provided an update on the company's development pipeline and reported financial results for the second quarter ended June 30, 2025. Dirk Thye, M.D., Quince's Chief Executive Officer and Chief Medical Officer, said, 'We achieved many critical milestones over the last quarter that significantly advance our research programs and strengthen our business model. Specifically, we completed enrollment in our pivotal Phase 3 NEAT clinical trial, secured additional financing to extend our operating runway sufficiently beyond topline results, and solidified our commercial development planning through our strategic partnership with Option Care Health. Quince remains confident in our ability to deliver topline results in the first quarter of 2026 and subsequent NDA submission in the second half of 2026, assuming positive study results.' Pivotal Phase 3 NEAT Clinical Trial Quince completed enrollment in its pivotal Phase 3 NEAT (N eurological E ffects of eDSP on Subjects with A - T; NCT06193200 / IEDAT-04-2022) clinical trial with a total of 105 participants, including 83 participants in the six to nine year-old primary analysis population and 22 participants aged 10 years and older. Quince expects to report topline results from its Phase 3 NEAT clinical trial in the first quarter of 2026. Concluding the NEAT study with 83 enrolled participants in the six to nine year-old primary analysis population reflects powering of approximately 90% to determine statistical significance of the primary endpoint. All 50 NEAT participants to date have elected to transition to the open label extension (OLE) study (NCT06664853 / IEDAT-04-2022). Participants who complete the full treatment period, complete study assessments, and provide informed consent are eligible to transition to the OLE study. The Phase 3 NEAT clinical trial is being conducted under a Special Protocol Assessment (SPA) agreement with the U.S. Food and Drug Administration (FDA). Assuming positive study results, the company plans to submit a New Drug Application (NDA) to the FDA in the second half of 2026. Quince was granted FDA Fast Track designation for the company's eDSP System for the treatment of patients with A-T based on the potential to address a high unmet medical need. NEAT is an international, multicenter, randomized, double-blind, placebo-controlled clinical trial to evaluate the neurological effects of Quince's lead asset, eDSP (dexamethasone sodium phosphate [DSP] encapsulated in autologous red blood cells; previously referred to as EryDex) in patients with A-T. Participants are randomized (1:1) between eDSP or placebo and treatment consists of six infusions scheduled once every 21 to 30 days. The primary efficacy endpoint will be measured by the change from baseline to last efficacy visit using the Rescored modified International Cooperative Ataxia Rating Scale (RmICARS) compared to placebo. Pipeline and Corporate Updates Announced a strategic relationship with Option Care Health, Inc. (Nasdaq: OPCH), the nation's largest independent provider of home and ambulatory infusion services, to support the commercial development and efficient launch of Quince's lead asset, eDSP, in the U.S. The strategic relationship will leverage Option Care's robust network of specialty pharmacy and ambulatory infusion suites to provide for the administration of eDSP in an effective and efficient way while delivering this innovative treatment to patients with greater geographic flexibility. Closed a private placement of common stock and accompanying warrants in June 2025 led by healthcare-focused institutional investor Nantahala Capital with participation from existing Quince stockholders including ADAR1 Capital Management, Legend Capital Partners, and Lagfin S.C.A., new stockholder Second Line Capital, along with members of Quince's senior management. Priced at a more than a 10% premium to the market price of Quince's common stock, the financing resulted in approximately $11.5 million in upfront proceeds and potential additional proceeds of up to $10.4 million, if the accompanying warrants are exercised in full, before deducting placement agent fees and other private placement expenses. Finalized Phase 2 clinical trial study designs to evaluate eDSP for the potential treatment of patients with Duchenne muscular dystrophy (DMD), the company's second targeted indication for its lead asset, eDSP. Quince plans to prioritize capital efficient study approaches, including potential investigator-initiated trials (IITs), to advance the evaluation of DMD as a second targeted eDSP indication. Initiated Study #3 in the company's European Union pediatric investigational plan (PIP) – named the P ediatric E ncapsulated D examethasone Sodium Phosphate (PeD) study – to evaluate the safety and pharmacokinetics of eDSP in younger patients with A-T who weigh between nine and 15 kilograms. Participated at the 2025 A-T Clinical Research Conference organized by the A-T Society, a leading A-T patient advocacy group based in the United Kingdom, where key opinion leaders (KOLs) presented post hoc data analyses from the company's prior Phase 3 ATTeST clinical trial, in addition to Quince management providing an overview of the Phase 3 NEAT clinical trial. Appointed Dr. Hassan Abolhassani, Assistant Professor of Clinical Immunology and Research Specialists in the Department of Medical Biochemistry and Biophysics at the Karolinska Institutet in Stockholm, Sweden, to the company's Scientific Advisory Board (SAB). Dr. Abolhassani becomes the ninth member to join Quince's SAB, which is comprised of leading experts in A-T, biochemistry, neurology, immunology, genetic, hematology, pharmacology, and clinical practice. Second Quarter 2025 Financial Results Reported cash, cash equivalents, and short-term investments of $34.7 million for the second quarter ended June 30, 2025. Quince expects its existing cash runway to be sufficient to fund the company's capital efficient development plan through Phase 3 NEAT topline results into the second quarter of 2026. If warrants related to the company's recent financing are exercised in full for cash, Quince's cash runway would extend into the second half of 2026. Reported research and development (R&D) expenses of $6.6 million for the second quarter ended June 30, 2025. R&D expenses primarily included costs related to ongoing Phase 3 NEAT clinical trial activities and related manufacturing costs. Reported general and administrative (G&A) expenses of $3.3 million for the second quarter ended June 30, 2025. G&A expenses primarily included personnel-related and stock-based compensation expenses, commercial planning and new product planning expenses, and other professional administrative costs. Reported a net loss of $16.1 million, or a net loss of $0.34 per basic and diluted share, for the second quarter ended June 30, 2025. Weighted average shares outstanding for the year were 46.7 million. Reported net cash used in operating activities of $21.0 million for the six months ended June 30, 2025. Cash used in operating activities was primarily due to net loss of $31.1 million for the period, adjusted for $9.9 million of non-cash items, including $4.5 million change in the fair value of warrants, $2.7 million in stock-based compensation, $2.5 million change in the fair value of contingent consideration liabilities, $0.8 million change in the fair value of the European Investment Bank loan, and a net decrease in operating assets of $0.5 million, offset by a net increase in accounts payable, and accrued expenses, and other current liabilities of $0.3 million. About Quince Therapeutics Quince Therapeutics, Inc. (Nasdaq: QNCX) is a late-stage biotechnology company dedicated to unlocking the power of a patient's own biology for the treatment of rare diseases. For more information on the company and its latest news, visit and follow Quince on social media platforms LinkedIn, Facebook, X, and YouTube. Forward-looking Statements Statements in this news release contain 'forward-looking statements' within the meaning of the Private Securities Litigation Reform Act of 1995 as contained in Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, which are subject to the 'safe harbor' created by those sections. All statements, other than statements of historical facts, may be forward-looking statements. Forward-looking statements contained in this news release may be identified by the use of words such as 'believe,' 'may,' 'should,' 'expect,' 'anticipate,' 'plan,' 'believe,' 'estimated,' 'potential,' 'intend,' 'will,' 'can,' 'seek,' or other similar words. Examples of forward-looking statements include, among others, statements relating to the timing, success, and reporting of results of the clinical trials and related data, including expected timing of Phase 3 NEAT topline results and submission of a related NDA; expected cash position and operating runway, including cash potentially receivable upon the exercise of warrants; current and future clinical development of eDSP, including for the potential treatment of Ataxia-Telangiectasia (A-T), Duchenne muscular dystrophy (DMD), and other potential indications; the strategic development path for eDSP, including the anticipated benefits of the strategic partnership with Option Care Health; planned regulatory agency submissions and clinical trials and timeline, prospects, and milestone expectations; and the potential benefits of eDSP and the company's market opportunity. Forward-looking statements are based on Quince's current expectations and are subject to inherent uncertainties, risks, and assumptions that are difficult to predict and could cause actual results to differ materially from what the company expects. Further, certain forward-looking statements are based on assumptions as to future events that may not prove to be accurate. Factors that could cause actual results to differ include, but are not limited to, the risks and uncertainties described in the section titled 'Risk Factors' in the company's Annual Report on Form 10-K filed with the Securities and Exchange Commission (SEC) on March 24, 2025, Quarterly Report on Form 10-Q filed with the SEC on May 13, 2025, and other reports as filed with the SEC. Forward-looking statements contained in this news release are made as of this date, and Quince undertakes no duty to update such information except as required under applicable law.
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Travel + Leisure
4 days ago
- Travel + Leisure
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Travel + Leisure
6 days ago
- Travel + Leisure
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