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Daughter to run 10km in memory of 'loving dad'

Daughter to run 10km in memory of 'loving dad'

Yahoo03-05-2025

A woman will be lacing up her running shoes to take part in a 10k (6.21mile) race to raise money for charity after losing her father to an incurable brain tumour.
Maisie Ball will be taking part in the Great Bristol Run on 11 May in memory of her father Nick Ball who died on 3 August, three-years after being diagnosed.
The money raised will be donated to Brain Tumour Research to help fund research towards finding new treatments for patients and a cure.
Ms Ball said: "I still can't fully put into words how much I miss him, but I know I want to help raise awareness, so others don't have to go through the same pain we did."
In August 2021, Mr Ball, 47, suddenly became confused and went to bed to rest after returning from a routine run.
Upon failing to wake him, his wife Rachel called an ambulance and he was rushed to intensive care at Southmead Hospital after suffering a seizure.
A scan confirmed he had a glioblastoma - an aggressive and incurable brain tumour.
The devastating news fell on the same day the family was celebrating Ms Ball's 16th birthday.
"I remember how brave both my mum and dad were in trying to make things feel normal for me. It's something I will never forget," recalled Ms Ball.
"Losing my dad to a brain tumour was like having the ground pulled out from under me. One minute, he was a strong, steady person, and the next, he was slipping away.
"It was heart-breaking to watch him change so quickly, and I felt so powerless."
Over the course of treatment, her father under went an awake brain surgery, an operation on his spine, nine rounds of chemotherapy and 45 sessions of radiotherapy.
On her fundraising page, Ms Ball wrote: "When we said our final goodbyes, I wrote a speech to read at his funeral and in this I promised dad I'd never take for granted my ability to move. So what better way to honour him by this 10k?
"I just know if he was here now for my training and my run I wouldn't hear him shut up about it and he'd be so proud".
Louise Aubrey, community development manager at Brain Tumour Research, said, "We are deeply moved by Maisie's dedication to raising funds and awareness in memory of her dad, Nick.
"Brain tumours have one of the lowest survival rates of any cancer, and more funding is desperately needed to change that.
"Maisie's participation in the Great Bristol 10K is an important step towards increasing awareness and vital funding."
Follow BBC Bristol on Facebook, X and Instagram. Send your story ideas to us on email or via WhatsApp on 0800 313 4630.
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Wildfire smoke can harm your brain, not just your lungs
Wildfire smoke can harm your brain, not just your lungs

Yahoo

time24 minutes ago

  • Yahoo

Wildfire smoke can harm your brain, not just your lungs

Wildfires are already burning in parts of Canada, and as they do, many communities are already facing the familiar thick haze as smoke drifts in. Smoke from wildfires has already led Environment Canada to issue air quality warnings for much of Ontario. In Toronto, smoke led to the city briefly having the worst air quality in the world. Anyone who has experienced wildfire smoke knows how it can leave you with a scratchy throat, stinging eyes and impact your lungs. However, smoke can also affect your brain. Tiny airborne pollutants found in smoke have been linked to increased risk of stroke, dementia and flare-ups in neurological diseases like multiple sclerosis (MS). These effects can disproportionately impact older adults, people with disabilities, Indigenous Peoples and those living in low-income communities. This isn't just about climate. It's about equity, and health systems need to catch up. Canada's 2023 wildfire season was the worst on record, and as climate change worsens wildfires, it may be a sign of what's to come. Alongside harmful gases and heavy metals, wildfire smoke contains fine particulate matter, also known as PM2.5. These tiny particles can travel deep into your lungs, slip into your bloodstream and even reach your brain. Some even bypass the lungs entirely, entering the brain directly through the nose. After entering the brain, these toxins can cause inflammation and stress, damage nerve cells and even accelerate cognitive decline. Studies have linked exposure to air pollution to an increased risk of stroke and dementia. Even short-term spikes in smoke exposure, like those during wildfires, lead to a surge in emergency visits for strokes, especially among people over 65. A 2022 experiment had thousands of adults participate in an online attention task under smoky conditions. It found that just a three-hour spike in fine particulate matter, typical of a heavy smoke episode, led to measurably worse attention scores. This fits other evidence that breathing smoke makes people mentally foggy, forgetful or fatigued. In 2024, a study found that chronic exposure to wildfire-related air pollution significantly increased the likelihood of someone being diagnosed with dementia. The risk was most pronounced in low-income communities, where people often have less access to clean air, health care and protective measures. For people already living with neurological conditions like MS or Parkinson's disease, the stakes are even higher. Exposure to fine particulate pollution has been linked with increased hospital admissions for MS relapses, particularly in young patients. Other research points to worsening symptoms of epilepsy and cognitive decline under extreme heat and polluted air conditions. Despite these mounting risks, neurological health considerations have been largely absent from wildfire preparedness initiatives and public health responses. That needs to change. If you want to stay informed about local smoke exposure, tools like AQmap can help you track PM2.5 levels in real time across Canada. Some face far greater risk from wildfire smoke than others, including older adults, those with pre-existing health conditions, people with lower socio-economic status, Indigenous populations, people residing in remote areas and children. This is a health equity issue as much as a medical one. Each of these groups faces unique and compounding challenges during smoke events. For example, older adults are more vulnerable to the cardiovascular and neurological effects of smoke. They also face greater barriers to accessing filtered environments. People with disabilities or chronic illnesses, including those with neurological conditions, often can't relocate during smoke events and may rely on power-dependent medical devices that can fail during climate emergencies. Low-income families are more likely to live in housing without proper air filtration or cooling. These same communities often face higher baseline rates of neurological disease. Indigenous communities, more than 80 per cent of which are located near fire-prone areas, face recurring displacement, interruptions to care and disproportionate exposure to smoke each summer. Children and adolescents are particularly susceptible to the harmful neurological effects of wildfires. Because their brains are still developing and they breathe more air per body weight than adults, children are especially vulnerable to harmful pollutants. Studies have linked early-life exposure to fine particulate matter with an increased risk of neuro-developmental disorders, lower cognitive function and structural brain changes. These populations aren't just more exposed, they also have fewer resources to respond. Recognizing these inequities, we are developing a climate-health equity framework for Canada, with a specific focus on neurological health. Our interdisciplinary team is asking: how can we build health systems that protect vulnerable brains during climate emergencies? Health-care workers in Alberta Health Services have designed the Climate-Resilient Acute Care Clinical Operations Framework. This framework supports hospitals in becoming both greener and more resilient, ensuring care can continue during wildfires, floods and extreme heat events. Importantly, it also centres the needs of equity-deserving populations, integrating climate adaptation into emergency care, supply chains, staffing and patient communication. What needs to change? Public awareness must expand beyond respiratory health. Neurological effects of smoke should be included in public health messaging, especially for high-risk groups. Health systems must be climate-ready, with clean air shelters, evacuation protocols and services tailored to meet the needs of neurological patients. Communities need support, from funding for air filtration to co-ordinated outreach during smoke events. Indigenous-led fire stewardship and community health initiatives should be part of national planning. Supporting Indigenous-led fire stewardship not only strengthens wildfire response but also respects Indigenous sovereignty and traditional ecological knowledge. Clinicians must be empowered to address climate-related health risks. Training in environmental health, including its impact on the brain, is increasingly essential. Wildfire season is back, and with it, an urgent need to protect more than just our lungs. The science is clear: breathing smoky air affects our minds, especially for those already facing health and social vulnerabilities. Climate change is a brain health issue. Building a healthier, more equitable future requires us to treat it that way, starting now. This article is republished from The Conversation, a nonprofit, independent news organisation bringing you facts and trustworthy analysis to help you make sense of our complex world. It was written by: Dr Bhavini Gohel, University of Calgary and Muskaan Muse Laroyia, University of Calgary Read more: Managing forests and other ecosystems under rising threats requires thinking across wide-ranging scenarios As wildfires become more frequent and intense, how will persistent smoke exposure affect long-term health? Wildfire season is changing in Canada — posing even greater risks to the nation's communities and ecosystems Dr Bhavini Gohel works for the Canadian Coalition for Green Healthcare. Muskaan Muse Laroyia does not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

Demyelinating Diseases Therapeutics Market to Reach USD 45 Billion by 2034, Growing at 6.3% CAGR
Demyelinating Diseases Therapeutics Market to Reach USD 45 Billion by 2034, Growing at 6.3% CAGR

Yahoo

time3 days ago

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Demyelinating Diseases Therapeutics Market to Reach USD 45 Billion by 2034, Growing at 6.3% CAGR

Demyelinating Diseases Therapeutics Market Outlook 2025-2034 Luton, Bedfordshire, United Kingdom, June 06, 2025 (GLOBE NEWSWIRE) -- The global market for demyelinating diseases therapeutics is witnessing notable growth and transformation, fueled by the increasing prevalence of neurological disorders and the introduction of innovative treatment solutions. Valued at approximately USD 25 billion in 2024, the market is projected to reach an estimated USD 45 billion by 2034, progressing at a steady Compound Annual Growth Rate (CAGR) of 6.3% during the forecast period from 2025 to 2034. Download PDF Brochure: A major contributor to this expansion is the rising incidence of multiple sclerosis (MS), along with other related disorders such as neuromyelitis optica (NMO), acute disseminated encephalomyelitis (ADEM), and chronic inflammatory demyelinating polyneuropathy (CIDP). The market is undergoing significant advancements through personalized medicine, biologics, and digital health integrations, shaping the way therapies are developed and delivered. Market Segmentation: A Detailed Breakdown The demyelinating diseases therapeutics market is categorized across several parameters including product type, therapeutic application, disease type, route of administration, distribution channels, therapeutic class, and patient demographics. Among product types, monoclonal antibodies, corticosteroids, and immunomodulators dominate due to their high efficacy and role in managing autoimmune responses central to these diseases. Multiple Sclerosis (MS) remains the largest disease segment due to its global prevalence, impacting nearly 2.8 million individuals worldwide. This segment benefits from a strong drug pipeline and sustained investment in research and development. In contrast, diseases like NMO and CIDP, though less prevalent, are becoming more prominent due to improved diagnostic capabilities and novel drug approvals. When it comes to therapeutic applications, Disease-Modifying Therapies (DMTs) are pivotal. These therapies reduce relapse rates and slow disease progression, particularly in MS, capturing the lion's share of the market. Symptomatic treatments, though secondary in market size, are essential for improving patients' quality of life and remain indispensable in overall disease management strategies. Route of Administration and Distribution Channels The preferred routes of administration in this market include injectable, oral, and infusion-based methods. Injectables lead due to their rapid efficacy and widespread use in administering monoclonal antibodies. However, oral therapies are quickly gaining popularity for their convenience and higher patient adherence, which could shift the administration landscape in coming years. From a distribution perspective, hospital pharmacies remain the dominant channel, especially for therapies requiring medical supervision or administration. Meanwhile, online pharmacies are emerging as strong contenders due to their convenience and role in chronic disease management. This growth is driven by increased internet penetration, telehealth services, and changing consumer behavior. Therapeutic Class and Demographic Insights In terms of therapeutic classification, biologics are leading the charge. These include monoclonal antibodies and recombinant proteins that target specific immune pathways. Biologics offer superior efficacy and fewer side effects, making them the preferred option in many treatment regimens. However, small molecules continue to hold value due to their affordability, oral availability, and ease of production, especially in cost-sensitive markets. Demographically, adult patients comprise the majority due to the typical onset age of MS and related disorders. However, pediatric treatments are on the rise as early diagnosis improves. The geriatric population is another growing segment, supported by the aging global population and increasing incidence of neurological conditions in older adults. These patients often require specialized care due to comorbidities and age-related drug interactions. 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The U.S., in particular, plays a significant role with supportive regulatory policies and well-established pharmaceutical players. Europe follows closely, contributing approximately 30% to the market. Growth in this region is propelled by increasing awareness, government-supported healthcare systems, and a favorable environment for clinical research. Countries like Germany, France, and the UK are key hubs for drug development and patient care. The Asia-Pacific region is the fastest-growing market with a projected CAGR of 8% through 2034. Factors such as economic development, expanding healthcare infrastructure, and rising disease prevalence contribute to this rapid growth. Nations like China, India, and Japan are investing heavily in healthcare, which supports both access and innovation in therapeutic offerings. Latin America and the Middle East & Africa are also emerging as regions with untapped market potential. While they currently hold smaller shares, their projected CAGRs of 7% and 6% respectively reflect strong future growth, particularly in urban centers with improving access to care. Key Market Drivers The momentum in this market is largely attributed to scientific and technological advancements, including the development of next-generation therapies like monoclonal antibodies and targeted biologics. The rise of personalized medicine, where treatments are tailored based on patient-specific genetic and biomarker profiles, is reshaping therapeutic strategies. Regulatory developments are also influential. Accelerated approval pathways, especially for orphan and breakthrough therapies, have reduced time-to-market for promising treatments. In tandem, increased global healthcare spending, particularly in neurological and autoimmune sectors, is bolstering the adoption of advanced therapies. Challenges and Restraints Despite promising growth, the market faces a number of hurdles. 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Perimenopause or MS
Perimenopause or MS

WebMD

time4 days ago

  • WebMD

Perimenopause or MS

Get me off this ride already! The hormonal fluctuations during this perimenopause stage I'm going through are driving me nuts. This is the wildest roller coaster of my life. My MS is angry. HELP PLEASE! On previous blogs, I've mentioned that multiple sclerosis and menses are declared public enemies. And sometimes, nature is a little too generous with women. We get our first period when we're little girls. Then, it goes on and on and on for decades. If that's not enough, after we reach a certain age, we enter the infamous transition period called perimenopause. And when you have MS, it hits you like a train. I'm a hot mess! Literally. If I was miserable trying to find balance and peace between my period and multiple sclerosis, now I'm at war with my own body. I feel like I hit the wall at 100 miles per hour, but I'm still alive. I can't wait for menopause! Every time I have my period, my MS symptoms amplify, which is expected. But now, not only are they amplified to the third power, but they're constant. From the entire cycle, I think I have two good days. My hypersensitivity is to the roof. The mood swings are intense. I'm depressed for the first time in my life. Like, I've been through hell and back, and never had depression before. Sometimes, I feel like I'm acting out of character, and I'm not proud of it. But what can I do? I can't control what's happening inside of me. On top of that, the fatigue – the lack of energy – hit me like a ton of bricks. Not to mention the brain fog. Ugh! I'm hot and sweaty. Gross! The temperature intolerance is off the hook. Can anybody hear the sirens? Tornado warning! What makes the perimenopause period exhausting is that it's a gradual transition. It could last several years before you get to menopause. So, while we still have our period, which is already hard enough, we have all these different symptoms lingering around, out of control and making the calls. The irony? We're expected to ride this wave with a smile on our face. Perimenopause could worsen MS symptoms and increase the progression of the disease. Sometimes, it's hard to pinpoint whether it's MS or perimenopause. Neurodegeneration shows brain volume loss and gray matter reduction in perimenopausal women with multiple sclerosis. Sleep disruption could also contribute to cognitive decline, depression, fatigue, and memory issues. No wonder I've been so dysfunctional in all areas. I've always had problems with poor sleep, but now it's worse. I'm in need of more sleep than prior to perimenopause. I'm exhausted! Like Cher said once in an interview when she was asked: 'What do you think of getting old?' And she quickly answered: 'It sucks!' I'm there with her. 'Moving forward in time,' which I prefer to say, really takes you by surprise, and makes you look back and ask, 'Where did time go?' Various symptom management strategies are suggested, like increasing physical and brain exercises, as well as the use of medications like antidepressants or contraceptives. Mommy's little helpers to the rescue! It's so hard to be a woman. I'm starting to feel sorry for the people around me, really. I haven't been the friendliest person lately. I'm so irritable that I can't even live with myself. I mean, they're no saints either, but I definitely take things out of proportion sometimes. It's like their new hobby is to push my buttons. What's hilarious is that when I went to my gynecologist and she tested my hormonal levels, she says that I'm not even close to being in menopause and that all the levels look normal. Really? Then where is this demon inside of me coming from? She also mentioned that this phase that I'm in is like being in limbo. No joke? I could even get pregnant if I wanted to. Hilarious! So, everything looks great, everything is awesome, I'm just feeling completely decompensated and there's nothing tangible to blame. In the midst of all this, I've had to apply to my own life everything that I preach. I've been doing a lot of self-care, showing grace to myself, meditating, disconnecting, walking away, breathwork, etc. This new life challenge requires that I put a lot of work into myself and my needs. I'm trying to be patient with myself and to not be so hard on myself as well. It's hard to be me nowadays. I'm a wreck! But I will survive. There is no misfortune that lasts a hundred years nor a body that can resist it. This too shall pass. I send a hug and my best wishes to all the warriors out there reading this blog that are going through the same thing. My heart goes out to you. If you need a friend, find me on my social media or join me on our Facebook group.

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