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Move over Mediterranean food. Experts say this East African diet could be key to better health

Move over Mediterranean food. Experts say this East African diet could be key to better health

Yahoo06-04-2025
The Mediterranean diet may be a favourite among nutritionists, but a new study suggests that sticking to a diet local to a community in East Africa could be another key to good health.
The new study, which included 77 men and was published in the journal Nature Medicine, focused on the diet of the Chagga people, who live in northern Tanzania in the foothills of Mount Kilimanjaro.
It's rich in plants and fibres, featuring lots of whole grains, beans, and green vegetables.
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For two weeks, men living in rural areas who usually followed the traditional diet switched to a Western-style diet full of processed foods and salt, such as sausages, white bread, and fried chicken.
Meanwhile, town-dwelling men whose diets were more Western either switched to traditional foods for two weeks or added Mbege, a fermented banana drink with an alcohol content of 1 to 3 per cent, to their diets for a week.
The researchers then measured inflammation-related biomarkers in the men's blood, as well as changes to their gut microbiomes.
Switching from a traditional to a Western diet led to more inflammation, they found – but replacing a Western diet with traditional foods or drinking Mbege helped bring down inflammation, which is tied to health issues like heart disease, type 2 diabetes, and autoimmune diseases.
Some of these changes were still apparent a month after the experiment, the study found.
The results suggest that preserving traditional diets in sub-Saharan Africa – and adopting a similar diet for those further afield – could help reduce people's risk factors for chronic conditions linked to inflammation.
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"What people eat has a large impact on the immune and metabolic system," Dr Quirijn de Mast, the study's senior author and an associate professor at Radboud University Medical Centre in the Netherlands, told Euronews Health.
"It was quite unexpected that many of these effects really persisted," he added.
The researchers said that the benefits of the Chagga people's diet are likely due to how the key foods interact with each other, rather than any single superfood – similar to the Mediterranean diet, which emphasises fruits, vegetables, olive oil, and moderate amounts of fish and dairy.
"It's probably not one thing," de Mast said. "I think it's the entire diet".
Meanwhile, the fermentation process appears to enrich banana drink Mbege with microbes and chemical compounds that are good for the gut – but the researchers warned that the health benefits of the drink should be weighed against the alcohol content and possible contamination.
For people looking to incorporate the benefits of Mbege, de Mast recommends eating more fermented foods in general.
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Notably, the findings might not hold for diets across the East African region. There are more than 100 tribes in Tanzania, the study said, each with their own eating habits.
The researchers called for more studies on how various traditional diets across Africa affect people's health – especially because international nutrition guidelines don't always consider regional differences in food, culture, and genetics.
Timing is key. The rapid urbanisation of sub-Saharan Africa has come with dietary changes and less physical activity, and the region is now grappling with rising rates of obesity and related health problems.
"These heritage diets and their diversity really deserve more attention before they disappear, because I think we can really learn a lot," de Mast said.
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This is what happens to your body if your shoes don't fit right
This is what happens to your body if your shoes don't fit right

National Geographic

time7 hours ago

  • National Geographic

This is what happens to your body if your shoes don't fit right

Even comfortable shoes can throw your body out of alignment. Experts reveal how everyday footwear can trigger pain in your back, hips, knees, and more—and what to wear instead. Colored MRI-style X-ray shows a lace-up boot enclosing the foot and directing pressure along the arch and ankle. By shaping how the foot moves and bears weight, footwear like this can influence posture, gait, and pain throughout the body. Photograph By Nick Veasey,Science Photo Library You might not think much about your shoes when running errands—dropping the kids off, picking up groceries, swinging by the pharmacy. But the footwear you choose for these everyday moments could be shaping your health more than you realize. Ill-fitting footwear can worsen or cause foot ailments like bunions, corns, calluses, and toenail issues. 'Your feet are the foundation of your body,' says Miguel Cunha, a podiatrist and owner of Gotham Footcare. 'Having improper footwear, or shoes that are not supporting you, is going to have an impact on the rest of your body, whether it's from the standpoint of fatigue or creating imbalance in anatomical alignment.' Understanding what's behind these changes is the first step to preventing pain that can spread beyond your feet. How your shoes cause pain To move efficiently and without pain, your feet need footwear that supports their natural motion. 'Every time we walk, our feet need to be able to change shape,' says Otto Lam, a physical therapist at Good Reps Therapy. The heel should strike first, the foot should roll forward, and the toes should spread before pushing off—but the wrong shoe can disrupt this sequence. 'If someone with wider feet is in a narrow shoe, perhaps they won't be able to get their foot to fully conform to the ground, or, as we call it, pronate,' Lam says. That restriction can shorten steps and force the hips and lower back to work harder to move forward. Over time, these small compensations can lead to persistent pain, throw off your gait, strain your joints, and exacerbate balance issues. Colored MRI-style X-ray shows a stiletto shoe elevating the heel and forcing the foot into a downward angle. This altered position shifts body weight forward, changing gait mechanics and increasing strain on the knees, hips, and lower back. Photograph By Nick Veasey, Science Photo Library Certain shoe styles create their own problems. Flip-flops, for instance, 'can cause us to grip or claw our toes to keep [the shoes] on,' Lam says. The gripping prevents the toes from relaxing or spreading out, which is necessary for standard walking mechanics. Not only can it create tension in the arches, but it may also cause pain in the calf muscles. Flatter or worn shoes with little arch support can also cause inner knee pain. High heels shift body weight forward, straining the forefoot and lower back. Slip-ons, minimalist shoes, and platforms can limit stability or natural motion, causing muscles to overwork. (Why walking barefoot can actually help your feet.) Even a single uncomfortable shoe can change how you walk. 'Let's say my right foot is uncomfortable and not my left in that shoe that I choose for whatever reason,' Lam says. 'I'm going to shorten my stride and put more weight on the other leg putting more stress on that side's knee, hip, and lower back.' Whether it's a bad fit, worn-out cushioning, or a mismatch between shoe design and foot shape, the wrong footwear can quietly set off a chain reaction of discomfort throughout the body. How to identify shoe-related pain One of the first things Cunha asks his patients to do is place their shoes on the exam table—because the wear patterns tell a story. 'We all pronate when we walk, which is when our arch collapses. But if you overpronate then, you're obviously going to have more wear and tear on the inside of the shoe and on the heel.' This causes your foot to roll inward, followed by your leg, which can lead to various issues, including plantar fasciitis on the foot, Achilles tendonitis in the ankle, inner knee pain, hip pain, and lower back pain. (The overlooked key to fitness? Strengthening your joints and tendons.) To pinpoint the cause, Cunha often performs a gait analysis. Sometimes it's done in the office, but even a simple video of a patient walking toward and away from the camera can reveal abnormalities in stride or posture. These clues help determine whether pain stems from the body's mechanics or from footwear that doesn't match the wearer's needs. 'Even if you don't have foot problems, if you have back problems, I'd recommend custom orthotics,' Cunha says. While over-the-counter inserts can help in mild cases, custom orthotics are molded to your foot's unique shape and movement pattern, making them more effective for correcting imbalances that lead to chronic pain. How to find the proper footwear for you Once you know what's causing the pain, focus on finding shoes that match your foot shape and movement. Flat feet may benefit from stability shoes with firm midsoles, while high arches often need extra cushioning to absorb shock. Wide feet require shoes with a roomier toe box, while narrow feet may need a snugger fit to avoid slipping. Both Cunha and Lam recommend shopping for shoes in person. Not only can you test the fit for yourself, but you can also get your foot measured with a Brannock Device by someone who knows how to interpret the measurements. The device measures length, width, and arch length to determine the best shoe size. 'I always tell patients to buy their shoes at the end of the day when their feet are most swollen and they're in their worst shape due to the cumulative effect of effects of gravity,' Cunha says. Putting on a shoe that fits properly should provide some relief to your body. 'You can feel it in your back. You'll feel lighter. Even walking around the store, you'll feel your back pain ease up a little bit.' For durability and anatomical support, Cunha recommends choosing shoes approved by the American Board of Podiatric Medicine. 'The shoe brands I recommend are Hoka, Brooks, Saucony, New Balance, and ASICS,' he says. 'They're fit over fashion.' (The definitive list of running shoes for every kind of runner, according to pros.) It's also important to remember that even the best shoes have a lifespan. Walking or running shoes often last 300–500 miles, or about 6–12 months of regular wear. Everyday sneakers may last longer, but should be replaced when the tread wears down, the midsole feels flat, or new aches develop. Inspect them regularly for worn soles, compressed cushioning, or changes in support, and pay attention to any new aches in your feet or ankles that a shift in activity can't explain, Lam says. Ultimately, the right shoe is the one that feels good on both feet and supports the way you naturally move. 'Our bodies are interconnected,' Cunha says. 'You have to treat the whole body and treat its individual components.'

Off-the-shelf vaccine shows success against deadly cancers
Off-the-shelf vaccine shows success against deadly cancers

Axios

time9 hours ago

  • Axios

Off-the-shelf vaccine shows success against deadly cancers

An experimental vaccine targeting one of the most common genetic drivers of hard-to-treat pancreatic and colorectal cancers prevented their recurrence, raising hopes for an "off the shelf" treatment that can train the immune system to attack malignancies. Why it matters: If shown effective in further trials, the vaccine could become a particularly important tool in staving off the return of pancreatic cancer, which sees roughly 80% of surgically removed tumors recur within five years. What they're saying:"This was a trial all of us in the medical oncology world have been waiting for," said Tracy Proverbs-Singh, an oncologist at Hackensack Meridian's John Theurer Cancer Center. "We see these patients for five years, we see the recurrences, we have to re-treat them, and it's devastating. And after we finish chemo, there's not a lot we can do." Go deeper: The peptide vaccine targets the KRAS mutation that occurs in roughly 90% of pancreatic cancers and half of colorectal cancers. Researchers administered the shot, called ELI-002 2P, to 25 patients who'd received conventional treatments but still had small amounts of cancer left in their bodies and were at high risk of relapse. Half of patients had no relapse by 16.3 months, and median overall survival was 28.9 months — both exceeding historical norms, per the study in Nature Medicine. The greatest benefit was seen in patients who had strong T cell responses. At the 20-month mark, 17 of the 25 patients had strong immune responses with 11 of those patients having no recurrence and six having delayed recurrence. The latter successfully underwent further treatment. "All the 17 were still alive which is why we think there's optimistically, something real going on here, because that's much better than what we might have expected historically," said Zev Wainberg, co-director of the UCLA GI Oncology Program and one of the lead authors. Yes, but: Researchers do not yet understand why eight of the 23 patients did not develop a strong immune response as a result of the vaccine. Between the lines: Much of the enthusiasm around therapeutic cancer vaccines has centered on personalized mRNA technology. It is notable that researchers were able to use a non-personalized vaccine because it can be more easily developed at scale. "It's a big shot in the arm for the pancreatic cancer vaccine, which has been elusive in the context of us being able to get something that's effective in the early stages," said Madappa Kundranda, division chief for cancer medicine at Banner MD Anderson Cancer Center. Reality check: This is still a small Phase 1 trial and will require a more robust randomized controlled trial. Wainberg said the team has already completed such a trial and should have results back in 2026. What to watch: Pancreatic cancer, which has a five-year survival rate of around 13% in the U.S., could be treated very differently within the next two years as multiple new drugs targeting the same mutations are also developed.

A protein researcher shares his easy go-to breakfast for strong muscles and good health
A protein researcher shares his easy go-to breakfast for strong muscles and good health

Business Insider

timea day ago

  • Business Insider

A protein researcher shares his easy go-to breakfast for strong muscles and good health

If nutrition expert Stuart Phillips could pinpoint just one time in your day when you could amp up the protein, he suspects it might be at the breakfast table. As one of the world's leading experts on protein and a nutrition scientist who's been studying this macronutrient for decades, he says the protein craze has gone a little overboard lately, with products like protein water and protein ice cream becoming trendy. "Protein's appearing in places where I don't think it has any business," Phillips, a professor of human physiology and nutrition science at McMaster University, recently told the Zoe nutrition podcast. "Nobody's truly — in our societies — deficient in protein." Instead, he says, some people might be "just a little bit under what I think is the recommended intake" of protein — a problem that can be easily solved without adding any new pricey supplements or ultra-processed products to your day. His own protein-rich go-to breakfast is cheap, sustaining, and flexible. Greek yogurt has more protein and fewer carbs than regular yogurt Phillips is part of a growing chorus of researchers and nutrition buffs who acknowledge that our current recommended dietary allowances of protein are a little bit low for most people. "A meal where people — I don't say under-consume protein — but that tends to be carbohydrate-heavy is breakfast," he said. For decades, our morning meals have been too often steered by ultraprocessed carbs like cereals, pancake mix, muffins, and toast. "Carbohydrates and fats, they're fuel," he says, but "protein is the structural component of everything." For him, the easiest way to make breakfast a more protein-rich meal is to begin with a bed of yogurt, instead of bread. "My superfood at breakfast is Greek-style yogurt," he said. It's a little higher in protein than regular yogurt, and pairs easily with other healthy, nutrient-rich breakfast staples. "Throw some nuts, throw some seeds, throw some fruit in there — it's probably my go-to breakfast just about every day." If you have a cup of whole, plain Greek yogurt (20g) for breakfast, topped with a quarter cup of mixed nuts (5.5g), a teaspoon of chia seeds (1g), and half a cup of mixed berries (0.5g), that's already about 27 grams of protein. No matter who you are or what your muscle-building goals may be, you're well on your way to meeting your daily requirements that way. How much protein do you really need? A quick and dirty formula Nutrition experts don't quite agree on how much protein is too much, but Phillips says that many people have been overdoing it lately, overreacting to the idea that our recommended guidelines lowball us. "The pendulum becomes 'well we need to get protein because we're not getting enough' but that's not the message," he said. "Actually, a lot of people are getting more than enough." His current recommendation? Consume about 1 gram of protein per kilogram of your body weight each day. If you know your weight in pounds, divide that number by 2.2 to find your rough protein target, in grams. For example, someone who weighs 150 lbs should consume around 68 grams of protein. Older people should strive to get a bit more, maybe around 1.2 grams per kilo of body weight, Phillips said. Lots of influencers and wellness gurus are recommending way more than that. Dr. Peter Attia, a popular longevity physician, recommends more than double what Phillips does, at about 2.2 grams per kilo. We've been through this charade with other macronutrients before. First, carbs were touted as the health foods of the 1980s and 90s, then fat had its heyday in the 2000s. Now, it's protein's turn to be the rockstar macronutrient. Don't get caught up in this hype cycle. Researchers generally agree that anything more than 1.6 grams of protein per kilogram each day is overkill. "I do think that the benefits of protein probably stop a lot sooner than a lot of people are making out," Phillips said.

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