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Fewer wrinkles in one WEEK: The potent serum that works 11 times faster than standard retinol (and it's gentle, too)

Fewer wrinkles in one WEEK: The potent serum that works 11 times faster than standard retinol (and it's gentle, too)

Daily Mail​21 hours ago

You're constantly fine-tuning your beauty routine. If one of your primary goals is to reduce visible lines and wrinkles, you may have your work cut out for you. But if you're tired of that song and dance, it's time to turn your attention to Medik8.
The brand's Crystal Retinal Age Defying Night Serum could well be considered the end-all, be-all of anti-aging treatments — because it's available in multiple progressive strengths to help your skin become more tolerant over time.
Medik8 Crystal Retinal Age Defying Night Serum
Take control of aging skin once and for all with the serum clinically proven to reveal skin that both looks and feels younger in just a week.
It's available in six progressive strengths, making it easy for anyone — even those with sensitive skin — to take advantage of retinal's efficacy.
Used regularly, it virtually erases fine lines, wrinkles, and age spots while firming skin and leaving your complexion firm and glowing.
$85 Shop
Its key ingredient is retinal, a derivative of vitamin A that works 11 times faster than standard retinol to visibly reduce those signs of aging you've tried so desperately to erase. Fine lines? Deep-set creases? They're no match for this system.
It's really quite genius. Medik8 offers six different Crystal Retinal formulas. The first in the range is specifically designed to meet the needs of sensitive skin, which means even those who've never been able to use standard retinol can finally reap the rewards and see results — without the risk of those unwelcome side effects.
As your skin grows accustomed to the treatment, you can ladder up to beginner level 3 before advancing to levels 6, 10, and 20. The final formula in the range, 24, is for experts whose skin can tolerate the higher concentration.
The results are truly astonishing at every level. A whopping 100 percent of people felt the serum was 'gentle,' while 97 percent noted their skin looked more youthful.
Impressively, in a clinical trial participants experienced a 20 percent reduction in both wrinkles and dark spots, along with an 11 percent improvement in firmness.
Those are exactly the kinds of results you expert of an anti-aging product — but very few deliver the way that Medik8's game-changing solution does. In fact, it's clinically proven to smooth away wrinkles in just one week, with improved elasticity in four.
The benefits are the same no matter which formula you choose: a smoother, more radiant, more refined complexion that is free of stubborn wrinkles, dark spots, and congestion.
Medik8 stabilizes its formulas to ensure that they remain potent to the very end of the tube, so you never have to worry about them losing their efficacy. In other words, you truly get your money's worth — making this advanced skin care worth every penny.
Thousands of reviewers agree that it's made all the difference. 'Beautiful results with no side effects,' praised one shopper. 'My skin has never looked better, it's smooth and clear and starting to feel much firmer.'
'Really see a different in fine lines and skin texture using this! The texture is beautiful, a lovely silky formula that absorbs well and doesn't feel like it just sits on the skin,' raved another customer.
What more could you ask for than an anti-aging treatment that is both gentle and widely regarded for delivering visible results? Pick up the Medik8 Crystal Retinal Age Defying Night Serum and get set for a more youthful complexion!

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What's you REAL hearing age? Take this 30-second test to see
What's you REAL hearing age? Take this 30-second test to see

Daily Mail​

time2 hours ago

  • Daily Mail​

What's you REAL hearing age? Take this 30-second test to see

Life is full of loud noises - from rock concerts to crying babies and noisy football stadiums - so it's not surprising that our ears get weaker the older we get. But just how much should you be able to tune into at your age? Here, you can take a quick, 30-second test to find out. One of the most common types of hearing loss - presbycusis - happens as, while growing up, a person will gradually find it difficult to hear 'high-frequency' sounds, such as the voices of women and young children. According Decibel Hearing Services, this can happen for a number of reasons, including exposure to loudness, genetics and health issues. 'Many things affect our hearing as we age,' the National Institute on Deafness and Other Communication Disorders also explained. 'For example, changes in the inner ear that can affect hearing are common. Age-related changes in the middle ear and complex changes along the nerve pathways from the ear to the brain can also affect hearing.' Humans can typically hear frequencies between 20 Hz - 20,000 Hz. But these upper limits start to dwindle with age, so the average adult is much more likely to be between 15,000–17,000 Hz. Most people will comfortable be able to hear 8,000 Hz. However, those who are aged over 50 may struggle with hearing above 12,000 Hz, while people over 40 will struggle with more than 15,000 Hz. When it gets to around 17,000 Hz - only teenagers can typically hear these frequencies. Eargym have devised a test to see what your 'hearing age' is - starting at low frequencies well into the 200s Hz and going up to 200,000 Hz. At 70, many will be able to hear around 9,000 Hz, with the limit going up to about 10,000 for those in their 60s. At 50, 12,000 Hz is the upper limit, while at 40, it becomes 14,000 Hz. At 30, people will hear into 15,000 Hz, while at 20 it's about 17,000 Hz. Once you get into the teens, people may hear well up until 20,000 Hz. At 50, 12,000 Hz is the upper limit, while at 40, it becomes 14,000 Hz. At 30, people will hear into 15,000 Hz, while at 20 it's about 17,000 Hz One of the most common types of hearing loss - presbycusis - happens as, while growing up, a person will gradually find it difficult to hear 'high-frequency' sounds, such as the voices of women and young children Speaking to MailOnline last year, Andy Shanks, hearing health expert and co-founder at eargym, said: 'The majority of us will experience some form of hearing loss in our lifetimes. 'But if we can spot the signs early and make some small changes, we can take steps to protect our hearing and prevent future avoidable hearing loss.' He suggests using games such as this 30 second test to check your hearing regularly and pick up on any abnormal changes. 'Safe listening practices, such as the use of ear defenders, gigplugs and noise-cancelling headphones, can also make a big difference when it comes to protecting our hearing health long in the future,' he added. 'Hearing loss is one of the biggest modifiable risk factors for dementia and is strongly associated with poor mental health and cognitive decline. 'So taking care of our hearing at all ages is essential to protect not only our ears but also our minds.' Around 12million people in the UK are affected by hearing loss. It is associated with social isolation and cognitive decline, and is one of the biggest modifiable risk factors when it comes to developing dementia. Speaking to MailOnline last year , Andy Shanks, hearing health expert and co-founder at eargym, said: 'The majority of us will experience some form of hearing loss in our lifetimes' WHAT ARE THE SIGNS OF HEARING LOSS? Hearing loss is common, particularly when you get older. Hearing loss can affect a child's speech development and also their progress at school. It can be caused by something that can be easily treated or something more serious, so it is important to visit your GP. Common signs of hearing loss include: Difficulty hearing other people clearly and misunderstanding what they say, especially in noisy places Asking people to repeat themselves Listening to music or watching TV with the volume higher than other people need Difficulty hearing on the phone Finding it hard to keep up with a conversation Feeling tired or stressed from having to concentrate while listening Source: NHS Yet adults wait an average 8.9 years before seeking help. Research suggests hearing loss costs the UK economy £25bn a year in lost productivity and unemployment. Common signs you're suffering from hearing loss include asking people to repeat themselves, difficulty hearing on the phone and listening to music or the TV at a higher volume than other people need, the NHS warns. There are lots of possible causes of hearing loss, such as an ear infection, ear wax or age. But it could also be caused by a perforated eardrum, which causes a sudden hearing loss or Ménière's disease which can affect your balance and hearing. If you notice signs of hearing loss it is important not to self diagnose and visit your GP for a more thorough hearing test. It comes as in December, an American pharmacist has revealed 11 of the common medications that can trigger the uncomfortable sensation known as tinnitus. The condition, which affects more than 50 million people in the US, is a symptom of several medical conditions like ear injuries, earwax blockage or age-related hearing loss. Sometimes the noise is present in one or both ears and it is most commonly described as a ringing, but it can also present itself as a range of sounds including buzzing, roaring, and whistling. While there is no cure, pharmacist Ayesha Gulzar says there are things you can do to reduce its impact, starting with checking what medications you are taking. She explained: 'Certain medications cause tinnitus, which can be temporary or rarely permanent and depends on different factors. 'Common ototoxic drugs (drugs that can have toxic effects on the ears) include antibiotics, analgesics (pain relievers), blood pressure medications, anticonvulsants (anti-seizure drugs), and others.'

Sarepta reports second case of liver failure death after its gene therapy treatment
Sarepta reports second case of liver failure death after its gene therapy treatment

Reuters

time3 hours ago

  • Reuters

Sarepta reports second case of liver failure death after its gene therapy treatment

June 15 (Reuters) - Sarepta Therapeutics (SRPT.O), opens new tab on Sunday said there had been a second reported case of acute liver failure resulting in death after a patient received the company's gene therapy for a rare form of muscular dystrophy. The patient was undergoing treatment with Sarepta's therapy called Elevidys, which is the only gene therapy approved by the U.S. Food and Drug Administration for Duchenne muscular dystrophy patients aged four and above. The first instance of death was reported in March this year, a 16-year-old boy who died from acute liver failure months after receiving Elevidys. Liver damage is a known risk with Elevidys and other gene therapies that use adeno-associated viral vectors to infuse modified genes. Sarepta said it is taking steps to mitigate the risk of acute liver failure in patients by working to convene an independent group of experts in Duchenne and liver health to consider an enhanced immunosuppression regimen for Elevidys. It has also temporarily suspending shipments of the therapy and informed the FDA and global health authorities about the incident. Roche (ROG.S), opens new tab, which partners with Sarepta for commercialization of the gene therapy outside the United States, said in a separate statement on Sunday that it has paused the dosing of Elevidys in patients following the two cases of fatal acute liver failure.

Kara Tointon: Why I had a double mastectomy at 39
Kara Tointon: Why I had a double mastectomy at 39

Times

time6 hours ago

  • Times

Kara Tointon: Why I had a double mastectomy at 39

Last year I made one of the biggest decisions of my life. I chose to have a double mastectomy and have my fallopian tubes removed. I didn't have cancer, but my decision was driven by it. Six years ago, my mother, Carol, underwent chemotherapy for ovarian cancer. During that time, she was tested for the BRCA1 and 2 gene alterations, which put you at greater risk of breast and ovarian cancers, because we know they run in our family. It was suggested that my sister, Hannah, and I also take a test. We did so in our own time, when we felt ready. My result came back positive. Hannah's, thankfully, came back negative. She had convinced herself that we would enter the process together and so it took a moment for her to be able to talk about it, but she has been a rock for me and has been with me every step of the way. Finding out about the gene alteration gave us all a clarity and an explanation of the generations of women we'd lost in my family, all too early, to cancer. My mum had lost her mother to cancer at the age of 13. In 2002, my Auntie June died lost a ten-year battle to both ovarian and breast cancer and in 2019, two and a half years after her initial diagnosis and three months after my first son, Frey, was born, cancer claimed Mum's life too. For the next five years after my test I was put under 'surveillance' — I had mammograms and MRIs once per year. Doctors had told me about the option of having a mastectomy when I first took the BRCA alteration test in 2018, but I was hoping to have a second child before I went through any major surgery. The first scan showed a benign lump. When tested, this wasn't cancerous, but the risk suddenly felt a lot more real. When these lumps showed up again in a few more scans, it was enough to convince me that I wanted the double mastectomy. The process was surprisingly straightforward. After attending various meetings where everything was explained to me, I waited for the date of surgery. In April last year, I went into the Royal Marsden hospital for one night and returned home the next day with drainage tubes, two mesh layers under my skin where my breasts used to be, and implants underneath. The procedure usually takes up to three hours. My surgeon told me that, although some patients' are able to use fat from their abdomen and buttocks to reconstruct, this wasn't an option for me at this time, hence us choosing implants. Within a few weeks I was up and about; within two months I was able to lift things. The operation did take a mental toll — I found myself surprisingly tired for about three months, but to a certain extent that was overridden by the overwhelming sense of relief. I still have some procedures to complete but I'm very happy with the results and the decision I've made. Five months later, when I had just turned 40, I had a second surgery to remove my fallopian tubes, which reduced my risk of ovarian cancer without me needing to go into an early menopause. When I am closer to a natural menopause, I will have my ovaries removed to further reduce my risk. The procedure and my recovery was relatively quick, and again I only spent one night in hospital. One of the biggest fears people have around this type of surgery is the physical scars it leaves and, while I do have those, I don't worry about them. How you look becomes far less of a concern when you've seen your body heal from two potentially life-saving operations. I now live a peaceful life in Sogne, southern Norway, with my partner, Marius, and our two sons, but I hope I can use my experience to spread awareness of the tests and operations that can help defend against breast and ovarian cancer. Many people are afraid to speak about cancer; Mum certainly was. My childhood growing up in the picturesque Westcliff-on-Sea in Essex was joyful and I'm lucky to have such a close family, but there was one thing Mum would never speak about: her health. For me, speaking about my procedures with other women and hearing their stories makes me feel less alone. That's why I decided to share my experience on Instagram last month. I'd seen a video on my feed of somebody else sharing theirs and it gave me such comfort. At first I felt nervous posting something so personal, but the kind messages I received from other women, many of them going through the same thing, really moved me. Having the BRCA alteration test and preventive surgery is a personal decision and one with many different considerations, but it was the right one for me. I was able to take back some autonomy — cancer once dominated my family but I feel like I am no longer controlled by it. I will always grieve that more treatment options were not available to my mum, but I know that she would want me to give other women a message: don't ignore your body; confronting your health head-on could save your life. Kara is an ambassador for The Eve Appeal — the leading gynaecological cancers charity, which funds research and raises awareness for the prevention and earlier diagnosis of all gynae cancers. You can find information on BRCA gene alterations, genetic testing and preventive options at

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