logo
Researchers try new ways of preserving more hearts for transplants

Researchers try new ways of preserving more hearts for transplants

Washington Post17 hours ago
WASHINGTON — Two university hospitals are pioneering new ways to expand lifesaving heart transplants for adults and babies — advances that could help recover would-be heart donations that too often go unused.
The new research aims to overcome barriers for using organs from someone who dies when their heart stops. Called DCD, or donation after circulatory death , it involves a controversial recovery technique or the use of expensive machines.
Orange background

Try Our AI Features

Explore what Daily8 AI can do for you:

Comments

No comments yet...

Related Articles

High-Protein Food Market Size to Hit USD 117.44 Billion by 2034, Fueled by U.S. and Asia Growth
High-Protein Food Market Size to Hit USD 117.44 Billion by 2034, Fueled by U.S. and Asia Growth

Yahoo

time22 minutes ago

  • Yahoo

High-Protein Food Market Size to Hit USD 117.44 Billion by 2034, Fueled by U.S. and Asia Growth

According to Towards FnB, the global high-protein food market size is calculated at USD 56.69 billion in 2025 and is projected to surpass around USD 117.44 billion by 2034, representing a healthy CAGR of 8.43% during the forecast period from 2025 to 2034. Ottawa, July 17, 2025 (GLOBE NEWSWIRE) -- The global high-protein food market size was valued at USD 52.28 billion in 2024 and is expected to grow from USD 56.69 billion in 2025 to around USD 117.44 billion by 2034, expanding at a CAGR of 8.43% from 2025 to 2034, according to study published by Towards FnB, a sister firm of Precedence Research. The high-protein food market has grown substantially in recent years due to consumer awareness about the rising importance of high-protein foods and their benefits for weight management and overall health nutrition. The increasing fad for plant-based protein food options is also helping the market to grow as it is supported by the huge consumer base formed by vegans and consumers with dairy intolerance. Access the Full Study Instantly | Download Sample Pages of the Report Now@ Market Overview The high-protein food market has grown substantially in recent years due to rising awareness among consumers about the benefits of high protein foods consumption for overall health. Consumers today prefer protein-rich food options for better weight management and to maintain general health as well. Such health conscious attitude has given rise to a high demand for protein-rich food items such as dairy products and lentils. Veganism and dairy intolerance have also led to the growth of the plant-based protein industry. Consumers with such health concerns are inclined towards plant-based protein to meet their nutritional requirements. Plant-based protein is also gaining huge popularity as people prefer to intake sustainable food options and also are aware of the health risks related to fatty dairy and meat products rich in fat and bad cholesterol. The high-protein food market is also observing growth due to factors such as rapid urbanization, improving standard of living, and consumer awareness about adequate protein intake. Hence, the food industry has also incorporated protein-rich snacks and drink options for consumers to maintain their protein intake on the go. Consumers can also find plant-based protein food and snack options for vegans and people with dairy intolerance. Such options help people to maintain their nutritional intake during busy schedules as well. Innovation in Protein Foods: Market's Largest Opportunity Innovation in high-protein foods can help the high-protein food market grow in the foreseen period. The availability of protein-rich snacks and drinks allows consumers to consume them on the go while traveling or when outdoors. It is essential for consumers who have busy schedules and are unable to maintain their protein intake by having and cooking proper meals. A significant portion of this demand comes from millennials and Gen Z, who prioritize functional nutrition and healthy snacking. According to a 2024 NielsenIQ survey, over 60% of Gen Z consumers actively seek foods with added protein, and nearly 70% of millennials report consuming protein snacks daily. Key Highlights of High-Protein Food Market By region, North America dominated the high-protein food market due to high consumer demand for plant-based protein in the region. By region, Asia Pacific is expected to be the fastest growing region due to high awareness about high-protein foods and enhancing urbanization. According to product insights, the high-protein packed foods segment dominated the market in 2024 due to the ease and convenience provided to consumers with hectic schedules. According to product insights, the high-protein drinks segment is expected to be the fastest growing as it is the easiest form of high protein consumption. By distribution channel insights, the offline segment dominated the market in 2024 due to the fad of high-protein foods for overall well-being. By distribution channel segment, the online segment is observed to be the fastest-growing segment because of the easy availability of such foods on different e-commerce platforms. Key Innovations & Instances in Production Innovation High-protein Food Market: Ready-to-drink (RTD) protein shakes and protein bars are dominating retail shelves. Brands like Premier Protein and RXBAR have seen double-digit sales growth due to rising demand for clean-label, high-protein options. Plant-based protein innovations, using pea, chickpea, and rice proteins, have expanded the market to vegan and flexitarian consumers. Companies like No Cow and Orgain are leveraging this shift. Protein-enhanced everyday foods such as pasta, chips, yogurt, and even ice cream (e.g., Halo Top) are allowing consumers to integrate more protein into their routine without changing eating habits drastically. The rise of high-protein breakfast options like Greek yogurt, protein pancakes, and fortified cereals has addressed the nutritional gap for busy mornings. Major Product Types in High-Protein Food Market: Protein-Rich Dairy Products Greek yogurt Protein-fortified milk Cheese and cottage cheese High-Protein Snacks Protein bars Trail mixes with added protein Roasted chickpeas, nuts, and seeds Ready-to-Drink (RTD) Protein Beverages Protein shakes Protein smoothies Meal replacement drinks Protein-Rich Meat & Poultry Products Jerky (beef, turkey, chicken) Processed meat with added protein Lean cuts with high protein claims Egg & Egg-Based Products Hard-boiled eggs (pre-packaged) Liquid egg whites Protein omelets and wraps High-Protein Bakery & Breakfast Items Protein muffins, pancakes, and waffles Fortified cereals and granola Protein bagels and breads Plant-Based Protein Products Tofu and tempeh Plant-based meat alternatives Lentil, pea, or chickpea-based items Gain Comprehensive Market Insights – Download the Full Databook Today: What are Latest Trends in High-Protein Food Market? Innovation in protein foods is helping the growth of the high-protein food market. Today consumers can buy protein-rich snacks, drinks, food options, and other similar options to manage their protein intake on the go even after a busy schedule. Increased muscle mass due to high protein consumption helps in strength training encouraging the growth of the high-protein food market. Protein consumption helps one to stay fuller for a longer time and avoid unhealthy snacking. Hence, it leads to the growth of high-protein snacks and beverage consumption as well. Consumption of protein also helps in multiple health benefits such as healthier bones and managing blood pressure as it helps in lowering bad cholesterol levels. Market Dynamics What are the Growth Drivers of the High-Protein Food Market? One of the biggest growth drivers of the high-protein food market is consumer awareness about the benefits of protein intake. It helps in increasing muscle mass, keeping one fuller to control unhealthy cravings, strengthen bones, and manage blood pressure. Hence, consumers today prefer the intake of protein-rich snacks and beverages rather than oily, fried, and sugary snacks. Hence, the availability of protein-rich snacks and food options easily in online and offline stores is another major driver of growth of the market. The availability of plant-based protein options helps vegans to maintain their protein even while traveling or outdoors. Plant-based protein snacks such as protein bars, chips, crisps, dips, and drinks help the segment lead the market. How Does Consumer Skepticism Cause Challenge for High-protein Food Market? A high amount of protein consumption can cause multiple health issues. High amounts of protein foods involve full-fat dairy foods and fatty cuts. Excess consumption of such foods may increase cholesterol in the body causing blood pressure issues, heart problems, and various similar health risks. Intake of more than required protein and less fibre also causes constipation and stomach disorders. Hence, such obstructions can be barriers to the growth of the high-protein food market. High-Protein Food Market Regional Analysis Which Region Dominated the High-protein Food Market in 2024? North America led the high-protein food market in 2024, consumers in the U.S. and Canada drove demand for both animal- and plant-based protein snacks, powders, and beverages. Protein-rich foods align with strong fitness-focused wellness trends and widespread innovation in clean-label product lines. This shift is also evident in consumer behavior: between 2023 and 2024, online searches for "high protein" surged 39%, demonstrating deep and rising demand for protein-rich foods What to Expect from United States in High-protein Food Market? The U.S. protein landscape is rapidly evolving with expectations for further growth. Protein-enriched dairy products, notably cottage cheese reached USD 1.75 billion in sales, rising 18% year-over-year, fueled by TikTok-led recipe trends. Overall U.S. protein consumer behavior reflects escalation: 61% of U.S. consumers increased protein intake in 2024, up from 48% in 2019. Meat proteins remain essential, but protein-fortified snacks, functional foods, and plant-alternatives are rapidly expanding, offering broad category opportunities. How are Asian Countries Expanding in High-protein Food Market? Asia Pacific is seen to grow at the fastest rate during the forecast period, with countries like India, China, and Japan leading the charge. India accounted for a substantial share in region's whey protein market, while China followed closely with a notable one supported by the booming e-commerce sector and increasing demand for fortified foods. Additionally, plant-based proteins dominate nearly 60% of the APAC market, particularly in China and Southeast Asia, due to a strong cultural inclination toward vegetarian diets and sustainability. Innovations in algae, insect-based, and microbial proteins are also gaining traction. The region's expanding fitness culture, coupled with convenient high-protein snacks and beverages, is fueling demand especially among millennials and Gen Z consumers. With government-backed nutrition initiatives and robust product development, Asia Pacific is poised to remain a key driver of growth in the high-protein food landscape. Market Report Scope Report Attribute Key Statistics Base Year 2024 Forecast Period 2025 to 2034 Growth Rate from 2025 to 2034 CAGR of 8.43% Market Size in 2024 USD 52.28 Billion Market Size in 2025 USD 56.69 Billion Market Size by 2034 USD 177.44 Billion Dominated Region North America Fastest Growing Region Asia Pacific Regions Covered North America, Europe, Asia-Pacific, Latin America and Middle East & Africa Have Questions? Let's Talk—Schedule a Meeting with Our Insights Team: High-Protein Food Market Segmental Analysis Product Analysis The high-protein packed foods segment dominated the high-protein food market in 2024 due to the convenience provided by the segment to avoid cooking but still consume protein easily. Such convenient food options help consumers complete their protein intake of the day without the hassle of cooking meals. It is a boon for consumers with busy and hectic schedules. Protein-rich snacks such as protein bars, chips and crisps, dips, and protein drinks are gaining popularity due to their easy consumption and convenience to carry them easily outdoors or while traveling while ensuring health at the same time. It helps consumers to stay fuller for a longer time and avoid oily, fried, and sugary snacks. The high-protein drinks segment is observed to grow notably in the foreseen period as it is the easiest option to consume protein on the go without the hassle of cooking meals or arranging for appropriate ingredients. The segment is also helping the growth of the high-protein food market as consumers are always in search of protein-rich hydration options before and after a workout session. Protein-rich shakes and smoothie are some of the easy beverage options that help consumers maintain their protein intake of the day easily and keep a tap on their weight management options. Distribution Channel Analysis The offline segment of the high-protein food market dominated the market in 2024 through means such as gyms, convenience stores, health shops, and other similar places. It helps consumers to shop for different types of products under one roof and save time. It also allows consumers to get some professional health advice from professionals and clear any health doubts as well. The online segment of the high-protein food market expects notable growth in the expected timeframe as it is a convenient way to order high-protein foods from different e-commerce platforms. At such platforms, consumers can also get to look at some discounted product options and order the right product at the right prices. Such platforms help consumers order protein-rich foods at the convenience of sitting at home. Feel Free to Get in Touch with Us for Orders or Any Questions at: sales@ Additional Topics Worth Exploring: Gluten Free Food Market: The global gluten free food market size is increasing from USD 14.25 billion in 2025 and is expected to surpass USD 33.59 billion by 2034, with a projected CAGR of 10% during the forecast period from 2025 to 2034. Canned Food Market: The global canned food market size was reached at USD 122.72 billion in 2024 and is anticipated to reach USD 181.66 billion by 2034, growing at a CAGR of 4% over the next decade. Organic Food Market: The global organic food market size is expected to grow from USD 253.96 billion in 2025 to USD 660.25 billion by 2034, with a compound annual growth rate (CAGR) of 11.20% during the forecast period from 2025 to 2034. Frozen Food Market: The global frozen food market size is expected to grow from USD 214.32 billion in 2025 to USD 347.01 billion by 2034, at a CAGR of 5.50% over the forecast period. Sugar-Free Food Market: The global sugar-free food market size is expected to grow from USD 48.14 billion in 2025 to USD 83.2 billion by 2034, growing at a CAGR of 6.27% during the forecast period from 2025 to 2034. Vegan Food Market: The global vegan food market size is anticipated to grow from USD 22.38 billion in 2025 to USD 55.88 billion by 2034, with a CAGR of 10.7% during the forecast period from 2025 to 2034. Snack Food Market: The global snack food market size is expected to increase from USD 265.95 billion in 2025 to USD 468.76 billion by 2034, growing at a CAGR of 6.50% throughout the forecast period from 2025 to 2034. Food Additives Market: The global food additives market size is on a growth trajectory, with its valuation expected to nearly double over the next decade rising from USD 128.14 billion in 2025 to USD 214.66 billion by 2034. Key players in the High-Protein Food Market Nestlé S.A. (Switzerland) Danone S.A. (France) Glanbia plc (Ireland) Archer Daniels Midland Company (ADM) (U.S.) PepsiCo, Inc. (through its brand Quaker Oats) (U.S.) Cargill, Incorporated (U.S.) Hormel Foods Corporation (U.S.) Tyson Foods, Inc. (U.S.) The Kraft Heinz Company (U.S.) Unilever PLC (U.K.) Kerry Group plc (Ireland) General Mills, Inc. (U.S.) Recent Developments in High-Protein Food Market In April 2025, India's biggest FMCG brand, Amul, launched the world's first high-protein kulfi. The low-fat, prebiotic kulfi, has no added sugar and is healthy for consumers of all age groups. (Source- In April 2025, Nestle launched its new protein drink to support weight loss for GLP-1 medication consumers. The science-backed protein drink helps manage appetite, build muscle mass, and control sugar levels. (Source- Segments Covered in the Report By Product High-Protein Packed Foods High-Protein Drinks Protein Supplements By Distribution Channel Online Offline By Region North America U.S. Canada Asia Pacific China Japan India South Korea Thailand Europe Germany UK France Italy Spain Sweden Denmark Norway Latin America Brazil Mexico Argentina Middle East and Africa (MEA) South Africa UAE Saudi Arabia Kuwait Thank you for exploring our insights. For more targeted information, customized chapter-wise sections and region-specific editions such as North America, Europe, or Asia Pacific—are also available upon request For Detailed Pricing and Tailored Market Report Options, Click Here: Feel Free to Get in Touch with Us for Orders or Any Questions at: sales@ Unlock expert insights, custom research, and premium support with the Towards FnB Annual Membership. For USD 495/month (billed annually), get full access to exclusive F&B market data and personalized guidance. It's your strategic edge in the food and beverage industry: About Us Towards FnB is a global consulting firm specializing in the food and beverage industry, providing innovative solutions and expert guidance to elevate businesses. With an in-depth understanding of the dynamic F&B sector, we deliver customized market analysis and strategic insights. Our team of seasoned professionals is committed to empowering clients with the knowledge needed to make informed decisions, ensuring they stay ahead of market trends. Partner with us as we redefine success in the rapidly evolving food and beverage landscape, and together, we'll navigate this transformative journey. Our Trusted Data Partners Precedence Research | Statifacts | Towards Packaging | Towards Chemical and Materials| Nova One Advisor For Latest Update Follow Us:

Elevance Health Hit By Medicaid Troubles, Trims Outlook
Elevance Health Hit By Medicaid Troubles, Trims Outlook

Yahoo

time22 minutes ago

  • Yahoo

Elevance Health Hit By Medicaid Troubles, Trims Outlook

Elevance Health Inc. (NYSE:ELV) shares plummeted nearly 12% on Thursday after the health insurer reported second-quarter 2025 adjusted earnings that missed analyst expectations and significantly lowered its full-year guidance, overshadowing strong revenue growth. The company reported second-quarter 2025 revenues of $49.42 billion, up 14.3% year over year, higher than the consensus of $48.34 billion. The increase was driven by higher premium yields in the Health Benefits segment, recently closed acquisitions, and growth in Medicare Advantage membership, partially offset by membership attrition in the Medicaid Health reported adjusted earnings of $8.84 per share, missing the consensus of $9.20. The benefit expense ratio was 88.9%, an increase of 260 basis points year over year, reflecting higher medical cost trend primarily in Medicaid business and ACA health plans. The operating expense ratio was 10.1 percent, an improvement of 160 basis points. The adjusted operating expense ratio was 10%, an improvement of 140 basis points, primarily driven by expense leverage associated with growth in operating revenue and ongoing expense discipline as the company prioritizes investments to support long-term strategy. View more earnings on ELV Health Benefits segment operating revenue was $41.6 billion in the second quarter of 2025, up 12% compared to the prior year quarter, driven primarily by higher premium yields, recently closed acquisitions, and growth in Medicare Advantage membership, partially offset by lower Medicaid membership. Medical membership totaled approximately 45.6 million, a decline of 212 thousand from the first quarter of 2025, driven by lower Medicaid membership and attrition resulting from lower effectuation rates in Individual ACA business. Operating revenue for Carelon was $18.1 billion, up 36%, driven by recent acquisitions in home health and pharmacy services, growth in CarelonRx product revenue, and the scaling of risk-based capabilities in Carelon Services. Guidance Elevance Health lowered its fiscal year 2025 adjusted earnings guidance from $34.15-$34.85 per share to approximately $30, versus the consensus of $34.40. 'We are updating our outlook to reflect elevated medical cost trends in ACA and slower rate alignment in Medicaid. While the external environment continues to evolve, we are focused on the areas within our control – managing healthcare costs, deploying targeted investments in advanced technology and value-based care delivery, and reinforcing the operational foundation that supports long-term value creation,' said Gail Boudreaux, President and CEO, in a statement on Thursday. Industry Context and Peer Impact This guidance shock from Elevance Health follows a similar move by Centene Corp (NYSE:CNC). Centene recently withdrew its entire 2025 GAAP and adjusted diluted EPS guidance. This decision by Centene was prompted by its initial review of 2025 industry data from Wakely, an independent actuarial firm. Centene's analysis indicated lower-than-anticipated market growth and significantly higher implied market morbidity (prevalence of illness) in their Health Insurance Marketplace states, leading to a substantial reduction in their expected risk adjustment revenue transfer. These events highlight a broader industry concern among health insurers regarding elevated medical costs and challenges in accurately predicting risk and pricing in government-sponsored programs like Medicaid and the ACA. Price Action: ELV stock is trading lower by 11.8% to $303.92 at last check Thursday. Read Next:Photo by Jonathan Weiss via Shutterstock UNLOCKED: 5 NEW TRADES EVERY WEEK. Click now to get top trade ideas daily, plus unlimited access to cutting-edge tools and strategies to gain an edge in the markets. Get the latest stock analysis from Benzinga? This article Elevance Health Hit By Medicaid Troubles, Trims Outlook originally appeared on © 2025 Benzinga does not provide investment advice. All rights reserved.

Which IV Iron Formulation Is Right for Your Patient?
Which IV Iron Formulation Is Right for Your Patient?

Medscape

time23 minutes ago

  • Medscape

Which IV Iron Formulation Is Right for Your Patient?

This transcript has been edited for clarity. Matthew F. Watto, MD: Welcome back to The Curbsiders . I'm Dr Matthew Frank Watto here with my great friend and America's primary care physician, Dr Paul Nelson Williams. Paul, are you a fan of iron? Paul N. Williams, MD: You know it! That's why we've done about 12 episodes on iron at this point. Watto: As in, pumping iron? Williams: Sure, look at me — I'm jacked! Watto: Paul, we had a great guest on this episode, Dr Tom DeLoughery (@Bloodman). He was a great guest and a hilarious guy. Let's talk about it, Paul: microcytic anemia. I know iron deficiency can cause that, but what else can cause microcytic anemia? Williams: I appreciated the breakdown of this episode. Our guest says that there are four big things that can cause microcytic anemia that you need to know about. One is iron deficiency; that is far and away probably the most common one. Then there is anemia of chronic disease, which I don't think we think about as much. If the mean corpuscular volume (MCV) is less than 70 fL, it's probably not anemia of chronic disease, but anemia of chronic disease can cause microcytic anemia. The next is thalassemia, which is probably more common than we give it credit for. The last one is sideroblastic anemia, which is something you're probably not going to be diagnosing in adulthood and is an uncommon cause. So really, if you consider those first three causes — especially with the framework that he gives — it can be pretty easy to distinguish between iron deficiency, anemia of chronic disease, and thalassemia. That's what you need to figure out before we start just giving iron willy-nilly. Watto: I don't think I've ever even seen sideroblastic anemia in a chart outside of an exam setting. I feel like you're more likely to see consumption written in the chart than sideroblastic anemia! Williams: Yeah, I feel like it's the type of disorder I would've been quizzed about during floors a million years ago but not something I've actually seen — ever, I don't think. Watto: Now, Paul, when I'm working up anemia, I like to look at all the things: red cell distribution width (RDW), total iron binding capacity (TIBC), iron. Is that a waste of my time, Paul? Williams: I would never call it a waste of your time. I'm sure it's of academic interest, but both our guest and I, in my own practice, don't spend too much time dwelling on those when we're chasing down microcytic anemia. Dr DeLoughery does not look at the TIBC all that often. It really is the ferritin, the MCV, and the hemoglobin that are the big-ticket items when you're working up iron deficiency anemia. The rest is all largely window dressing, according to him. I feel good about that, because I don't like sweating out equations and working through those things. Watto: Okay, so we're looking for low hemoglobin. An MCV of less than 80 fL or so is usually considered microcytic in most labs. Now, the ferritin cutoff was an interesting one. Some labs might say 15 ug/dL or less. Some labs say 30 ug/dL or less. Dr DeLoughery recommends a ferritin cutoff of 30 ug/dL or less. But for most patients, we're usually going to treat to at least a ferritin of 50 ug/dL, because if patients are fatigued from iron efficiency, they usually feel better once we achieve a ferritin level of 50 ug/dL or higher. But we should remember that the reason why the lab cutoffs are lower is because they're looking at population average. And because iron deficiency anemia is so common and a large portion of our population has iron deficiency, the average ferritin values are lower than what ideal, healthy levels should be. If you just measured ferritin among patients with normal iron stores, the ferritin cutoff would be much higher. Paul, what do you think about these specific ferritin cutoffs that he recommended? Have you heard about that before? Because when I was prepping for this, I was unfamiliar with those cutoff values and what values we should consider when determining treatment. Williams: Do you mean in terms of when symptoms actually occur? Watto: Yes. For example, he said that for patients experiencing fatigue, you want to get the ferritin to 50 ug/dL or higher. And then he mentioned two other symptoms: restless legs and hair loss. Williams: Yeah, and for restless legs, you need to get ferritin above 75 ug/dL to actually achieve adequate iron levels in the brain. And then for hair loss, your goal is to get to at least 100 ug/dL to reverse the hair loss, if iron deficiency is indeed the contributing cause and not just getting old. Watto: For a lot of patients, they might need IV iron to get their levels up that much. Dr DeLoughery checks levels every 3 months or so, for the most part, because you want to give it some time to re-equilibrate after you give the iron. Now, Paul, when I'm trying to get those ferritin levels up, I usually tell my patients to take their iron with coffee and tea. Is that a bad thing to do? Williams: Bad news for us, Matt, and for the rest of the world. But yes, unfortunately coffee and tea can reduce your absorption of iron, so you should probably avoid drinking either of those within an hour of taking your oral iron supplementation. If you want to boost absorption, you can take your supplement with meat protein. So, substitute steak instead of your coffee, I guess? There's also always an ongoing debate and discussion about vitamin C potentially increasing iron absorption. Our guest, Dr DeLoughery, is a fan of it, but I think the jury is still largely out as far as that goes. Watto: And it seems like coffee and tea really impact iron absorption. I think he said it's like 80% or 90% decreased absorption; it was very significant. Williams: I know we have a long history of championing coffee in terms of being good for everything, but this might be the one instance where you don't necessarily have to avoid it; you just have to delay it. Watto: Yeah, exactly. Just make sure to avoid taking your iron within an hour (on either side) of coffee consumption and you're good to go. Williams: That would still be a real problem for me. Watto: When you have a continuous IV of coffee, that doesn't give you much time to get the iron in, Paul! Williams: Yep, and speaking of IVs… Watto: I just wanted to quickly shout out some IV iron formulations. The ones that I've had more experience with are IV iron sucrose and ferric gluconate. The reason I'm most familiar with those are because they are the cheaper formulations and they happen to have been on formulary. However, those are not the best formulations if you have the options, because the newer formulations can be given quicker and in a single dose or two doses compared to the ones I just mentioned, which need 4-8 weeks of weekly IV doses to administer the amount we'd like. Dr DeLoughery liked low-molecular-weight iron dextran because it comes in 1000 mg and you can give it within an hour. This is the formulation we discussed with Dr Auerbach back in 2018. Dr Auerbach told us that when you give low-molecular-weight iron dextran to your classic anemia patient — let's say a young woman with iron deficiency who has a hemoglobin of 7 g/dL — they'll start to feel better before the iron is even done infusing! It's pretty well proven. Williams: Yeah, patients will experience a reduction in ice craving as they're receiving the treatment, which is wild. Watto: Paul, why would it be a bad idea if I gave someone ferumoxytol — which comes in a dose of 510 mg and you have to give it twice — before I was going to, say, send them for an MRI? Williams: In that specific circumstance, it's important to know that ferumoxytol can impact MRIs because it acts like contrast. And that effect can persist for 3 months after the infusion itself, so you can significantly alter the results of your MRI and make the imaging hard to interpret if you don't space those things out. That would be one reason to avoid ferumoxytol, if you're planning on upcoming imaging. Watto: The other IV iron formulation that I was really excited to try out was ferric carboxymaltose. It comes in at 750 mg per dose, so you can give one or two doses depending on the severity of iron deficiency. But why might that be a bad idea? Williams: It's nice of you to ask. So, there's the possibility of symptomatic hypophosphatemia with ferric carboxymaltose, which, again, is wild. It's always a delightful surprise to discover the terrible things you could potentially do — even though they are, by and large, safe. Watto: The hypophosphatemia sounds bad because it sounds like if you try to give the patient phosphate, it gets worse because the body just accelerates how quickly it's getting rid of phosphorus. It's bad, Paul. So, I will not be giving that one. Ever. Williams: Yeah, I don't think I've ever ordered that one happily. I would probably avoid it if I had better options available.

DOWNLOAD THE APP

Get Started Now: Download the App

Ready to dive into a world of global content with local flavor? Download Daily8 app today from your preferred app store and start exploring.
app-storeplay-store