Quest Diagnostics to Offer FDA-Cleared Fujirebio Blood Test for Alzheimer's Disease
SECAUCUS, N.J., July 9, 2025 /PRNewswire/ -- Quest Diagnostics (NYSE: DGX), a leader in diagnostic information services, including advanced diagnostics for brain health, today announced it plans to offer laboratory testing based on the Lumipulse® G pTau 217/β-Amyloid 1-42 Plasma Ratio in-vitro diagnostic (IVD) test from Fujirebio, a global leader in the field of high-quality IVD testing.
Quest plans to make the test available to physicians and biopharmaceutical collaborators later this summer. The test is the first blood-based IVD test cleared by the U.S. Food and Drug Administration (FDA) to aid in identifying patients with amyloid pathology associated with Alzheimer's disease. It is designed to aid the clinical assessment of Alzheimer's disease in adult patients aged 50 years and older presenting at a specialized care setting with signs and symptoms of cognitive decline.
Through its AD-Detect™ portfolio, Quest provides a suite of advanced lab-developed blood tests regulated under CLIA for assessing patients with cognitive impairment for Alzheimer's disease. The Fujirebio test offering extends this portfolio to include an FDA-cleared option for use in specialized care settings.
"Our goal is to advance access to quality and innovative blood-based tests for Alzheimer's disease. Adding the Fujirebio test to our existing blood-based tests provides the many physicians we serve with another powerful option for assessing patients for Alzheimer's disease," said Kathleen Valentine, Vice President and General Manager, Neurology, Quest Diagnostics. "Blood-based testing can be less invasive and more convenient than traditional test methods. We are excited to leverage our expansive network of patient service centers to broaden access to the Fujirebio innovation to help more at-risk individuals gain access to the insights they need sooner."
In a clinical study population of 499 patients, which closely mirrors US demographics, and when applying a dual cut point, the FDA-cleared test demonstrated a positive predictive value (PPV) of 92% and a negative predictive value (NPV) of 97%, with 20% of patients uncertain to have amyloid pathology, thus requiring further testing.
Quest will showcase its complete line up of Alzheimer's and other neurological test innovations at this year's Alzheimer's Association International Conference (AAIC) in Toronto from July 27-31.
"As brain health and Alzheimer's disease interventions continue to evolve, diagnosing patients earlier, when interventions can be most effective, is critical," said Michael Racke, MD, a board-certified neurologist and Medical Director of Neurology, Quest Diagnostics. "We are constantly looking for ways to help physicians and patients make the most informed decisions, and this new addition to our test menu will aid that goal."
While amyloid PET imaging and cerebral spinal fluid testing are established methods for aiding the diagnosis of Alzheimer's disease, they are significantly more expensive, invasive and specialist-dependent than blood-based tests. With a physician's order, patients can conveniently provide a blood draw for testing for the Fujirebio test and any of the AD-Detect™ tests through Quest's network of patient sites. Quest maintains approximately 8,000 patient access points, including an extensive patient service center network of approximately 2,000 locations in the U.S., as well as phlebotomists in physician offices and mobile phlebotomy services. Specimens will be transported for testing to Quest's state-of-the-art laboratory in San Juan Capistrano, California.
Nearly 7 million Americans have Alzheimer's, the most prevalent dementia, a number projected to reach 14 million by 2060. Approximately 12-18% of adults over the age of sixty are living with mild cognitive impairment, a potential sign of AD. Seventy-seven percent of physicians say new therapies will transform Alzheimer's into a chronic, manageable disease, and 94% of physicians say blood tests would be more cost effective for the healthcare system compared to more invasive methods of detection (e.g., lumbar puncture, imaging studies) according to a special report from Quest.
Quest is committed to developing and offering innovative advanced diagnostics to aid in evaluating Alzheimer's disease and other brain diseases. For more information, visit www.QuestForTheCure.com.
About Quest DiagnosticsQuest Diagnostics works across the healthcare ecosystem to create a healthier world, one life at a time. We provide diagnostic insights from the results of our laboratory testing to empower people, physicians and organizations to take action to improve health outcomes. Derived from one of the world's largest databases of de-identifiable clinical lab results, Quest's diagnostic insights reveal new avenues to identify and treat disease, inspire healthy behaviors and improve healthcare management. Quest Diagnostics annually serves one in three adult Americans and half the physicians and hospitals in the United States, and our nearly 55,000 employees understand that, in the right hands and with the right context, our diagnostic insights can inspire actions that transform lives and create a healthier world. www.QuestDiagnostics.com.
View original content to download multimedia:https://www.prnewswire.com/news-releases/quest-diagnostics-to-offer-fda-cleared-fujirebio-blood-test-for-alzheimers-disease-302500634.html
SOURCE Quest Diagnostics
Hashtags
Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles
Yahoo
21 minutes ago
- Yahoo
Build better balance and serious leg strength with this six-move bench workout
When you buy through links on our articles, Future and its syndication partners may earn a commission. If you want to build serious leg strength, then you need to include unilateral exercises – movements that work on one side of your body at a time. This six-move workout from Fitness Trainer Joe Bronston focuses on just that to help improve your lower body stability, balance, and unlock serious single-leg strength. No squat racks or leg machines needed, just a workout bench and a set of heavyish dumbbells. 'Most people have a dominant side that does more work without them even realizing it,' he writes on his Instagram post. 'Over time, that can lead to poor movement patterns and nagging pain—especially in the knees, hips, or low back. Single-leg exercises help correct that. They force your body to activate stabilizing muscles, improve joint alignment, and fire up your glutes in a way most bilateral movements just can't.' For this workout, perform three sets of each of the exercises below for the required reps, on each leg. Rest for 1-2 minutes between each exercise round and opt for a medium to heavy weight, where the last couple of reps feel like a challenge, without your form being compromised. If you're not sure how to perform any of the exercises, then just take a quick watch of the short video above. Here's the workout: Bulgarian split squats – 8-10 reps Single leg hip thrusts – 10 reps Supported single leg Romanian deadlift – 10 reps Goblet lateral lunge butt taps – 10 reps Alternating step-ups – 10 reps Goblet box squats – 15 reps Now it's time to hit the upper half. We've got plenty of bench-focused workouts, and this upper body session is perfect to save for later in the week. It targets your arms, chest, shoulders, and back, and with a bit of grit, you can knock it out in just 35–40 minutes. Then, if you're looking to round out your week with one final push, try this superset full-body workout – it's efficient, effective, and designed to save you time without sacrificing results.
Yahoo
25 minutes ago
- Yahoo
Dermatologists Say This One Trick Is A Surefire Way To Treat Visible Leg Veins
"Hearst Magazines and Yahoo may earn commission or revenue on some items through these links." As a child, I'd always noticed the veins on my mom's legs. In the summertime, when she'd wear shorts or sit with her feet up on the couch, I'd see the web of tiny red and purple lines weaving across her calves and ankles. They were just part of her legs, like freckles or tan lines, but they stuck with me. And by the time I hit my mid twenties, I started spotting those same patterns on my own body. The web-like marks, which I later learned are called spider veins, are incredibly common, especially in women. While harmless, they can be bothersome to some, but acting early can prevent and minimize their appearance significantly. 'The earlier you start intervention, the better,' says Rachel Nazarian, MD, a board-certified dermatologist in New York City. 'If you recognize that visible veins run in your family, and you see early signs of on your own legs, be diligent about wearing compression stockings regularly.' Meet the experts: Rachel Nazarian, MD, is a board-certified dermatologist in New York City. Marisa Garshick, MD, is a board-certified dermatologist in NYC. Todd Harris Wolf is a celebrity and editorial makeup artist in New York City. But stockings are just the beginning: If you're in the early stages of seeing spider veins or wondering what to do about the larger, bumpier kind (those are called varicose veins), I talked to doctors about what causes them, how to treat them, and how to prevent them. Plus, find out what to do when you want a quick (read: instant) fix. Most often, our veins go undetected underneath the skin, shuttling nutrient-rich blood from our heart to our other organs. When they become damaged, they start showing up—usually on the legs, but they can also appear on the face. Both spider and varicose veins are essentially damaged blood vessels. Spider veins are broken capillaries (so they're not technically veins) that can look red, blue, or purple. Varicose veins are larger, bulging veins that may appear twisted or raised, and oftentimes symptoms like aching or swelling can accompany their appearance. While spider veins are mostly cosmetic, varicose veins can sometimes point to a more serious issue, such as chronic venous insufficiency (when your leg veins can't send blood to your heart). There's a strong genetic component—thanks, Mom—when it comes to developing spider or varicose veins. So, if your relatives had them, chances are you might too. But lifestyle and environmental factors can also play a role. Sitting or standing for long hours, pregnancy, and even just the normal aging process can all raise your risk for spider or varicose veins. Hormonal fluctuations (like those during pregnancy or menopause) can increase your risk as well. Other overlooked causes include trauma or injury and even 'certain types of exercise that put extra pressure on the legs, such as heavy weightlifting,' says Marisa Garshick, MD, a board-certified dermatologist in NYC. There are a few different ways you can zap leg veins away, and they're usually done at a dermatologist's office. These treatments offer permanent results, but 'occasionally new veins can form nearby or in other areas,' Dr. Nazarian says. Lasers are the go-to for small, superficial spider veins. Both Drs. Nazarian and Garshick recommend Nd:YAG lasers for leg veins. These lasers emit a specific wavelength of light that targets the blood in the vein. 'The blood absorbs the energy from the laser, heating up, which then causes the veins to either collapse and scar down or to rupture and break,' Dr. Nazarian says. The treatment can be very quick, with minimal discomfort, and the small veins tend to respond well. However, each vein has to be treated individually, which can be tedious, and there's a risk of your skin staining brown, which may linger for months or longer. I visited Dr. Nazarian's New York City office to try the YAG laser on a cluster of spider veins around my ankle and a couple of others behind my knee and on my shin. While it wasn't exactly a spa day, the process was quicker and less painful than I expected. The zap feels like a rubber band snap, and there's a bit of redness afterward, but the veins disappeared in real time. There's no downtime with laser, and Dr. Nazarian said to wait about four weeks to see if I noticed any tell-tale skin staining and if I need another round to fully get rid of the veins. For medium to larger spider veins or clusters, sclerotherapy tends to be more effective. 'Sclerotherapy involves injecting a sclerosant—either a liquid or foam—into the vein,' which causes it to shut down and fade over time, Dr. Garshick says. After injecting, your dermatologist may massage the area and monitor you for a bit after. Most people have to wear compression socks for up to 3 weeks after getting treated with sclerotherapy, according to the American Academy of Dermatology Association (AAD). When it comes to choosing between sclerotherapy and laser to treat veins, it's important to factor in the number, location, and exact size of the veins. Larger veins or clusters do better with injections, while tiny telangiectasias (spider veins) may respond to YAG laser, Dr. Nazarian says. For larger varicose veins or those with underlying venous insufficiency, endovenous laser therapy (EVLT) may be the way to go. 'EVLT is reserved for larger varicose veins stemming from underlying venous insufficiency,' Dr. Garshick says. This is a more invasive procedure that requires making a small incision under local anesthesia to allow a thin laser fiber to seal off affected veins, redirected blood flow to other healthier veins. Laser or sclerotherapy sessions can range from $300 to $1,000, depending on the extent of treatment. And while cosmetic cases are typically not covered by insurance, 'in some cases, if the veins are causing pain or swelling, treatments may be covered,' Dr. Garshick says. While veins treated by one of the above procedures typically don't come back, they're a chronic conditioner and new ones can form over time, Dr. Nazarian says. That makes it extra important to do what you can to prevent them from forming in the first place. And if you're genetically prone to visible veins: 'The earlier you start intervention, the better,' Dr. Nazarian says. Wear compression stockings, especially if you stand or sit for long periods. (Both Dr. Nazarian and Dr. Garshick recommend wearing them regularly to help prevent blood pooling in the legs.) Elevate your legs when resting. Avoid prolonged sitting or crossing your legs. Exercise regularly to improve circulation. Protect your legs from injury or trauma. Maintain a healthy weight.$22.37 at If you've spotted drugstore products that promise vein-erasing magic, our experts say not to expect miracles—they're mostly just marketing. 'Topical creams can't reach nearly deep enough to collapse the veins and they don't have enough power to fight blood pressure within the vessels,' Dr. Nazarian says. But there is one product that can make a major difference in the appearance of visible veins: makeup. Certain products can temporarily camouflage spider and varicose veins when you want a bit of an airbrushed finish. Celebrity makeup artist Todd Harris Wolf says to look for body makeup with a 'film former,' which means it's self-setting and won't transfer to clothing or furniture. Typically, these products will be labeled as 'transfer-proof,' 'water-proof,' or 'sweat-resistant.' In 12 adaptable and buildable shades, this high-performance body foundation can fade even the most visible of veins. It's forgiving finish won't draw attention to textured skin and it contains SPF 25 to prevent further damage. $40.00 at product has more of an illuminating finish (so not the best option for varicose veins) but offers incredible coverage, making it ideal for very dark and prominent spider veins. It's sweat-, water-, and transfer-proof for twenty-four hours and comes in 7 buildable shades. $49.00 at veins that require coverage but not major camouflage, this product delivers handily. It has the most natural-looking finish, says Harris Wolf, and is buildable so you can customize how it works on your skin. SPF 15 is the icing on top. $52.00 at These products should be applied to clean, dry skin that hasn't been moisturized with lotions or oils, which can degrade the formula and cause it to break down. To apply, Harris Wolf likes to use a large, dense body brush like the Anisa Pinnacle Face & Brush to buff the product in for a seamless finish. 'This imparts a overall streak-free look, but you can also use your fingers to dab makeup directly onto more prominent veins. Wait about 15 minutes for the makeup to fully set and then blot any excess with a tissue,' he says. For bulging veins that create a textured look on skin, Harris Wolf says it's important to use a matte-finish product rather than one with a more radiant or glowing finish, which will only exacerbate their appearance. So, you may not be able to avoid turning into your mother entirely, but you can certainly keep your legs in the best possible shape. And that's worthy of a high kick. You Might Also Like Jennifer Garner Swears By This Retinol Eye Cream These New Kicks Will Help You Smash Your Cross-Training Goals
Fast Company
26 minutes ago
- Fast Company
Why Walmart just pulled 850,000 water bottles off the shelves
Walmart is recalling hundreds of thousands of reusable water bottles after multiple customers reported injuries, some of them going blind. The Consumer Product Safety Commission (CPSC) announced the recall of Ozark Trail 64 oz Stainless Steel Insulated Water Bottles last week, alerting consumers of the potential hazard and telling them to stop using the products immediately. 'The lid can forcefully eject, posing serious impact and laceration hazards, when a consumer attempts to open the capped bottles after food, carbonated beverages or perishable beverages, such as juice or milk, are stored inside over time,' the recall notice explained. The notice also stated that some of the injuries related to the product have been serious. 'Walmart has received three reports of consumers who were injured when struck in the face by a lid forcefully ejected from these bottles upon opening. Two consumers suffered permanent vision loss after being struck in the eye.' The now-recalled product is not new to Walmart shelves. It's been on the market since 2017. However, it seems injuries have only just been recently reported. The product itself does not contain the model number, however, the number, 83-662, can be found on the packaging. The bottles measure 4.41 by 4.41 by 11.5 inches, the agency noted. In a statement to the Associated Press, Walmart said, 'The health and safety of our customers is always a top priority' and said the brand has 'fully cooperated' with CPSC to take the product off of shelves and alert customers to the danger. The company is offering full refunds for the water bottles and directed customers to return the water bottles to Walmart stores. CPSC directed customers to call Walmart directly at 800-925-6278 or visit or for additional information. Water bottles have become somewhat of a fashion statement, surging in popularity in recent years. But along with the rise in popularity has also come an uptick in safety concerns. Last year, Stanley made headlines after TikTokkers began testing the water bottles for lead, and in some cases, finding it. The company initially said there is no lead in the products, then later, clarified the statement to explain that lead is used in the manufacturing process, but that cups would have to be damaged for the lead to be exposed. A law firm sued the maker of Stanley cups over the concern, and other lawsuits followed.
