Red Sox at Astros prediction: Odds, expert picks, starting pitchers, betting trends, and stats for August 13
Walker Buehler is slated to take the mound for Boston against Hunter Brown for Houston.
The series is now tied at one game apiece following Boston's shellacking of the Astros, 14-1, last night. Alex Bregman homered again against his former team as part of the 13-hit onslaught. Dustin May had his best outing of the season throwing six innings of five-hit shutout ball for the Sox.
Lets dive into the series finale and find a sweat or two.
We've got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.
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Game details & how to watch Red Sox at Astros
Date: Wednesday, August 13, 2025
Time: 7:10PM EST
Site: Minute Maid Park
City: Houston, TX
Network/Streaming: NESN, SCHN
Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.
Odds for the Red Sox at the Astros
The latest odds as of Wednesday:
Moneyline: Red Sox (+141), Astros (-167)
Spread: Astros -1.5
Total: 8.0 runs
Probable starting pitchers for Red Sox at Astros
Pitching matchup for August 13, 2025: Walker Buehler vs. Hunter Brown
Red Sox: Walker Buehler (7-6, 5.40 ERA)
Last outing: August 8 at San Diego - 0.00 ERA, 0 Earned Runs Allowed, 4 Hits Allowed, 2 Walks, and 4 StrikeoutsAstros: Hunter Brown (9-5, 2.51 ERA)
Last outing: August 8 at Yankees - 3.38 ERA, 2 Earned Runs Allowed, 4 Hits Allowed, 1 Walks, and 5 Strikeouts
Red Sox: Walker Buehler (7-6, 5.40 ERA)
Last outing: August 8 at San Diego - 0.00 ERA, 0 Earned Runs Allowed, 4 Hits Allowed, 2 Walks, and 4 Strikeouts
Astros: Hunter Brown (9-5, 2.51 ERA)
Last outing: August 8 at Yankees - 3.38 ERA, 2 Earned Runs Allowed, 4 Hits Allowed, 1 Walks, and 5 Strikeouts
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Top betting trends & insights to know ahead of Red Sox at Astros
The Red Sox have won 4 of their last 5 games against AL West teams
The Under has cashed in 10 of the Astros' last 12 home games with Hunter Brown on the mound
Hunter Brown has struck out at least 5 in each of his last 5 starts and in 7 of his last 8 outings
Rookie Roman Anthony has hit in 5 straight games (7-19)
If you're looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!
Expert picks & predictions for tonight's game between the Red Sox and the Astros
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for Wednesday's game between the Red Sox and the Astros:
Moneyline: NBC Sports Bet is staying away from a play on the Moneyline.
Spread: NBC Sports Bet is leaning towards a play ATS on the Boston Red Sox at +1.5.
Total: NBC Sports Bet is recommending a play on the over on the Game Total of 8.0.
Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC
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