Common pain medication could reduce cancer spread, study finds
That's according to a new study from the University of Cambridge, which found that aspirin could reduce cancer metastatis (spread) by stimulating participants' immune systems.
The findings were published in the journal Nature on March 5.
In mouse models, scientists discovered that a certain protein called ARHGEF1 suppresses T-cells, which are immune cells that can pinpoint and attack individual cancer cells that break away from original tumors, according to a press release.
ARHGEF1 was "switched on" when T cells were exposed to thromboxane A2 (TXA2), a chemical produced by platelets that helps with blood clotting. Too much of TXA2 can increase the risk of heart attacks and strokes.
That's where aspirin comes in — it is already known to stop the production of TXA2 and prevent clotting, which is why it may be recommended to prevent cardiac events in some people.
"Aspirin, or other drugs that could target this pathway, have the potential to be less expensive than antibody-based therapies."
"This new research found that aspirin prevents cancers from spreading by decreasing TXA2 and releasing T cells from suppression," the press release stated.
In mice with melanoma, the ones that were given aspirin had less frequent metastases of the cancer compared to those who were not given the medication.
"It was a 'eureka' moment when we found TXA2 was the molecular signal that activates this suppressive effect on T cells," stated first author Dr. Jie Yang from the Department of Pathology at the University of Cambridge in the release.
"Before this, we had not been aware of the implication of our findings in understanding the anti-metastatic activity of aspirin," he went on.
"Aspirin, or other drugs that could target this pathway, have the potential to be less expensive than antibody-based therapies, and therefore more accessible globally."
Previous studies have suggested that daily aspirin treatment is associated with reduced cancer spread in humans with the disease and with reduced cancer mortality in patients without metastasis, noted senior researcher Dr. Rahul Roychoudhuri, professor of cancer immunology at the University of Cambridge.
In one randomized controlled trial, taking 600 milligrams of aspirin daily for an average of 25 months substantially reduced cancer incidence in carriers of hereditary colorectal cancer.
Pashtoon Kasi, MD, medical director of gastrointestinal medical oncology at City of Hope Orange County in California, reiterated that previous research has linked aspirin use with a reduced risk of cancer, particularly gastrointestinal tract cancers.
"It has been identified in numerous studies with mixed results on reducing the risk of recurrence and/or improving outcomes in patients with metastatic cancer," Kasi, who was not involved in the research, told Fox News Digital.
"This new study further demonstrates how aspirin and other inhibitors of this pathway could be used in new treatments to prevent the cancer from metastasizing or spreading."
Roychoudhuri, the senior researcher, encouraged caution in applying the findings.
While aspirin is low-cost and widely available, its long-term use is not without "significant risks," he said, including stomach bleeding and haemorrhagic stroke, particularly in older individuals.
"This is why we emphasize that patients should not start taking aspirin for cancer prevention without specific medical advice from their doctor," he said in a statement to Fox News Digital.
"The risk-benefit calculation varies substantially between individuals based on age, comorbidities and concurrent medications," the doctor noted. "Patients interested in aspirin therapy should discuss it with their oncologist or family practitioner, who can evaluate the potential benefits against the risks."
Kasi pointed out the study's potential limitations, primarily that the research was conducted on mice models rather than humans.
"The study also did not take into account complications that some people who use aspirin regularly experience, such as bleeding or interactions with other medications," he noted.
"However, it builds upon the growing body of evidence … and provides mechanistic insights into how this effect might occur from an immune perspective."
Kasi agreed that patients should talk to their doctor to discuss the benefits and health risks associated with regular aspirin use.
"In some cases, low-dose aspirin or other anti-inflammatory drugs are already being considered in clinical use, as well as in additional trials – for example, for individuals born with Lynch syndrome who have a higher predisposition to developing colorectal, endometrial and other cancers," he noted.
The scientists are planning to conduct more research — through the Add-Aspirin clinical trial, which will recruit more than 10,000 patients with early-stage breast, colorectal, gastroesophageal and prostate cancers across the U.K. and India — to determine whether aspirin can stop or delay the recurrence of these cancers.
"Patients interested in aspirin therapy should discuss it with their oncologist or family practitioner, who can evaluate the potential benefits against the risks."
"Our research suggests aspirin could potentially be most beneficial for patients with early-stage cancers who have been treated with curative intent but might harbor undetected micrometastases," Roychoudhuri said.
"However, further clinical validation is needed before specific recommendations can be made."
For more Health articles, visit www.foxnews.com/health
The research received funding from the Medical Research Council, the Wellcome Trust and the European Research Council.
The Add-Aspirin clinical trial is funded by Cancer Research UK, the National Institute for Health and Care Research, the Medical Research Council and the Tata Memorial Foundation of India.
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Fossils show two types of ancient human ancestors lived at the same place and time. One was possibly an unknown species
Ancient, fossilized teeth, uncovered during a decades-long archaeology project in northeastern Ethiopia, indicate that two different kinds of hominins, or human ancestors, lived in the same place between 2.6 million and 2.8 million years ago — and one of them may be a previously unknown species. The discovery provides a new glimpse into the complex web of human evolution. Ten of the teeth, found between 2018 and 2020, belong to the genus Australopithecus, an ancient human relative. Meanwhile, three teeth, found in 2015, belong to the genus Homo, which includes modern humans, or Homo sapiens. The results were published Wednesday in the journal Nature. Such an overlapping of two hominins in the fossil record is rare, which had previously led scientists to believe that Homo appeared after Australopithecus, rather than the two being contemporaries. Australopithecus species walked upright much like modern humans, but had relatively small brains, closer in size to those of apes. The emergence of Homo species, with their larger brains, is easy for people today to view as some sort of evolutionary upgrade on a path to modern humanity. But the coexistence of the two demonstrates that hominins developed, and lived, in multiple varieties at once. 'This new research shows that the image many of us have in our minds of an ape to a Neanderthal to a modern human is not correct — evolution doesn't work like that,' said study coauthor Kaye Reed, research scientist and president's professor emerita at the Institute of Human Origins and emeritus professor at the School of Human Evolution and Social Change at Arizona State University, via email. 'Here we have two hominin species that are together. And human evolution is not linear, it's a bushy tree, there are life forms that go extinct.' Since 2002, Reed has been a codirector of the Ledi-Geraru Research Project, which is focused, in part, on searching for evidence of early Homo species. In 2015, the team announced the discovery of the oldest known Homo jawbone at 2.8 million years old. It has also searched for later evidence of Australopithecus afarensis, which first appeared 3.9 million years ago, but there is no sign of these ancient human relatives in the fossil record after 2.95 million years ago — suggesting they went extinct before Homo's first appearance. Australopithecus afarensis is best represented by the famed fossilized remains of Lucy, discovered in 1974 in Ethiopia. Lucy was shorter than an average human, reaching about 3.3 feet (1 meter) in height, had an apelike face and a brain about one-third the size of a human brain. Her fossil showcased a mixture of humanlike and apelike traits and provided proof that ancient human relatives walked upright 3.2 million years ago. When the team discovered the Australopithecus teeth during two separate digs in 2018 and 2020, it compared them with species such as afarensis and another hominin group known as garhi, but they didn't match up. Instead, the scientists believe the teeth belong to a previously unknown species of Australopithecus that walked the Earth after Lucy — and alongside an early Homo species. 'Once we found Homo, I thought that was all we would find, and then one day on survey, we found the Australopithecus teeth,' Reed said. 'What is most important, is that it shows again, that human evolution is not linear. There were species that went extinct; some were better adapted than others, and others interbred with us — we know this for Neanderthals for sure. So anytime that we have another piece to the puzzle of where we came from, it is important.' Cracks in Earth's surface The teeth were found in Ethiopia's Afar region, a key place for researchers seeking answers about human evolution. A variety of preserved fossils have been found there as well as some of the earliest stone tools, Reed said. The Afar region is an active rifting environment — the tectonic plates beneath its earth are actively pulling apart and exposing older layers of sediment that shed light on almost 5 million years of evolution, Reed said. 'The continent is quite literally unzipping there, which creates a lot of volcanism and tectonics,' said study coauthor Christopher Campisano, associate director and associate professor at the Institute of Human Origins and associate professor at the School of Human Evolution and Social Change at Arizona State, in a video the school released. 'At 2 1⁄2, 3 million years ago, these volcanoes spewed out ash that contain crystals called feldspars that allow us to date the eruptions that were happening on the landscape when they're deposited.' The Australopithecus teeth documented in the new study were dated to 2.63 million years ago, while the Homo teeth are from 2.59 million and 2.78 million years ago. But the team is cautious about identifying a species for any of the teeth until it has more data and more fossils. 'We know what the teeth and mandible of the earliest Homo look like, but that's it,' said Brian Villmoare, lead study author and associate professor in the department of anthropology at the University of Nevada, Las Vegas, in a statement. 'This emphasizes the critical importance of finding additional fossils to understand the differences between Australopithecus and Homo, and potentially how they were able to overlap in the fossil record at the same location.' The Australopithecus teeth broadly resembled those of the afarensis species in contour and the size of the molars, but features of the cusps and canine teeth had not been previously seen in afarensis or garhi teeth, Villmoare said. The teeth were also different in shape than those of any Homo species, or of the ancient human relative Paranthropus, known for its large teeth and chewing muscles. 'Obviously these are only teeth,' Villmoare said, 'but we are continuing field work in the hopes of recovering other parts of the anatomy that might increase resolution on the taxonomy.' Even just finding the teeth was a complicated task, according to Campisano. 'You're looking at little teeth, quite literally, individual teeth that look just like a lot of other of the little pebbles spread on the landscape,' he said in the video. 'And so, we have a great team of local Afars that are excellent fossil hunters. They've seen these things their entire lives walking around the landscape.' A blip for evolution The new study is important because it provides insight into a time frame from 3 million to 2 million years ago, a mysterious period in human evolutionary studies, said Dr. Stephanie Melillo, paleoanthropologist and assistant professor at Mercyhurst University in Pennsylvania. Melillo was not involved in this research, but she has participated in the Woranso-Mille Paleontological Research Project in the Afar Triangle of Ethiopia. Part of the problem in learning about this stretch of prehistory is how ancient layers of dirt were deposited over the course of history in eastern Africa. 'Erosion in rivers and lakes were at a low level and only a little bit of dirt was deposited in the Afar,' Melillo wrote in an email. 'That deposited dirt contains the fossils — of our ancestors and all the animals that lived with us. When there is little deposition, there are few fossils.' A key feature helping archaeologists to understand humanity's evolution are structural basins, or 'bowls' on Earth's surface that naturally collect layers of sediment better than the surrounding landscape does — like the Turkana Basin stretching across southern Ethiopia and northern Kenya, Melillo said. Previous research has found evidence to suggest that Homo and Paranthropus coexisted there 1.5 million years ago. The new study focuses on the Afar Depression, a basin to the north of the Turkana. 'This contribution by Villmoare and colleagues demonstrates that in the Afar there was also some other species around with Homo — but it isn't Paranthropus,' Melillo said. 'Instead, they identify this 'non-Homo' genus as Australopithecus. They do a very convincing job of demonstrating why the new fossils are not Paranthropus.' The study adds to growing evidence that Australopithecus was not roaming the Afar Depression alone, she said. A mysterious coexistence When Australopithecus and Homo were alive, the Afar Region, now mostly a semidesert, had much more seasonal variation in rainfall than it does today, Reed said. Millions of years ago, the environment there was still dominated by a dry season, but it was interrupted by a brief wet season. Rivers that carried water across the landscape existed for only part of the year. Few trees grew near the river, and the environment nearby was largely wetlands and grasslands. 'We have a fossil giraffe species that was eating grass, which probably indicates they were stressed as they eat trees and bushes almost every place else,' Reed said. 'Were the hominins eating the same thing? We are trying to find out by examining isotopes in their teeth and microscopic scratches on their teeth.' Understanding whether or not Homo and Australopithecus had the same food sources could paint a portrait of how our ancient ancestors shared or competed for resources, Reed said. The team also wants to try to identify which hominin made the stone tools found at the site. At the moment it's impossible to tell exactly how the two hominins coexisted, but Reed said she is hoping that future findings will provide more answers. 'Whenever you have an exciting discovery, if you're a paleontologist, you always know that you need more information,' Reed said. 'You need more fossils. More fossils will help us tell the story of what happened to our ancestors a long time ago — but because we're the survivors we know that it happened to us.' Sign up for CNN's Wonder Theory science newsletter. Explore the universe with news on fascinating discoveries, scientific advancements and more.
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13 hours ago
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Fossils show two types of ancient human ancestors lived at the same place and time. One was possibly an unknown species
Ancient, fossilized teeth, uncovered during a decades-long archaeology project in northeastern Ethiopia, indicate that two different kinds of hominins, or human ancestors, lived in the same place between 2.6 million and 2.8 million years ago — and one of them may be a previously unknown species. The discovery provides a new glimpse into the complex web of human evolution. Ten of the teeth, found between 2018 and 2020, belong to the genus Australopithecus, an ancient human relative. Meanwhile, three teeth, found in 2015, belong to the genus Homo, which includes modern humans, or Homo sapiens. The results were published Wednesday in the journal Nature. Such an overlapping of two hominins in the fossil record is rare, which had previously led scientists to believe that Homo appeared after Australopithecus, rather than the two being contemporaries. Australopithecus species walked upright much like modern humans, but had relatively small brains, closer in size to those of apes. The emergence of Homo species, with their larger brains, is easy for people today to view as some sort of evolutionary upgrade on a path to modern humanity. But the coexistence of the two demonstrates that hominins developed, and lived, in multiple varieties at once. 'This new research shows that the image many of us have in our minds of an ape to a Neanderthal to a modern human is not correct — evolution doesn't work like that,' said study coauthor Kaye Reed, research scientist and president's professor emerita at the Institute of Human Origins and emeritus professor at the School of Human Evolution and Social Change at Arizona State University, via email. 'Here we have two hominin species that are together. And human evolution is not linear, it's a bushy tree, there are life forms that go extinct.' Since 2002, Reed has been a codirector of the Ledi-Geraru Research Project, which is focused, in part, on searching for evidence of early Homo species. In 2015, the team announced the discovery of the oldest known Homo jawbone at 2.8 million years old. It has also searched for later evidence of Australopithecus afarensis, which first appeared 3.9 million years ago, but there is no sign of these ancient human relatives in the fossil record after 2.95 million years ago — suggesting they went extinct before Homo's first appearance. Australopithecus afarensis is best represented by the famed fossilized remains of Lucy, discovered in 1974 in Ethiopia. Lucy was shorter than an average human, reaching about 3.3 feet (1 meter) in height, had an apelike face and a brain about one-third the size of a human brain. Her fossil showcased a mixture of humanlike and apelike traits and provided proof that ancient human relatives walked upright 3.2 million years ago. When the team discovered the Australopithecus teeth during two separate digs in 2018 and 2020, it compared them with species such as afarensis and another hominin group known as garhi, but they didn't match up. Instead, the scientists believe the teeth belong to a previously unknown species of Australopithecus that walked the Earth after Lucy — and alongside an early Homo species. 'Once we found Homo, I thought that was all we would find, and then one day on survey, we found the Australopithecus teeth,' Reed said. 'What is most important, is that it shows again, that human evolution is not linear. There were species that went extinct; some were better adapted than others, and others interbred with us — we know this for Neanderthals for sure. So anytime that we have another piece to the puzzle of where we came from, it is important.' Cracks in Earth's surface The teeth were found in Ethiopia's Afar region, a key place for researchers seeking answers about human evolution. A variety of preserved fossils have been found there as well as some of the earliest stone tools, Reed said. The Afar region is an active rifting environment — the tectonic plates beneath its earth are actively pulling apart and exposing older layers of sediment that shed light on almost 5 million years of evolution, Reed said. 'The continent is quite literally unzipping there, which creates a lot of volcanism and tectonics,' said study coauthor Christopher Campisano, associate director and associate professor at the Institute of Human Origins and associate professor at the School of Human Evolution and Social Change at Arizona State, in a video the school released. 'At 2 1⁄2, 3 million years ago, these volcanoes spewed out ash that contain crystals called feldspars that allow us to date the eruptions that were happening on the landscape when they're deposited.' The Australopithecus teeth documented in the new study were dated to 2.63 million years ago, while the Homo teeth are from 2.59 million and 2.78 million years ago. But the team is cautious about identifying a species for any of the teeth until it has more data and more fossils. 'We know what the teeth and mandible of the earliest Homo look like, but that's it,' said Brian Villmoare, lead study author and associate professor in the department of anthropology at the University of Nevada, Las Vegas, in a statement. 'This emphasizes the critical importance of finding additional fossils to understand the differences between Australopithecus and Homo, and potentially how they were able to overlap in the fossil record at the same location.' The Australopithecus teeth broadly resembled those of the afarensis species in contour and the size of the molars, but features of the cusps and canine teeth had not been previously seen in afarensis or garhi teeth, Villmoare said. The teeth were also different in shape than those of any Homo species, or of the ancient human relative Paranthropus, known for its large teeth and chewing muscles. 'Obviously these are only teeth,' Villmoare said, 'but we are continuing field work in the hopes of recovering other parts of the anatomy that might increase resolution on the taxonomy.' Even just finding the teeth was a complicated task, according to Campisano. 'You're looking at little teeth, quite literally, individual teeth that look just like a lot of other of the little pebbles spread on the landscape,' he said in the video. 'And so, we have a great team of local Afars that are excellent fossil hunters. They've seen these things their entire lives walking around the landscape.' A blip for evolution The new study is important because it provides insight into a time frame from 3 million to 2 million years ago, a mysterious period in human evolutionary studies, said Dr. Stephanie Melillo, paleoanthropologist and assistant professor at Mercyhurst University in Pennsylvania. Melillo was not involved in this research, but she has participated in the Woranso-Mille Paleontological Research Project in the Afar Triangle of Ethiopia. Part of the problem in learning about this stretch of prehistory is how ancient layers of dirt were deposited over the course of history in eastern Africa. 'Erosion in rivers and lakes were at a low level and only a little bit of dirt was deposited in the Afar,' Melillo wrote in an email. 'That deposited dirt contains the fossils — of our ancestors and all the animals that lived with us. When there is little deposition, there are few fossils.' A key feature helping archaeologists to understand humanity's evolution are structural basins, or 'bowls' on Earth's surface that naturally collect layers of sediment better than the surrounding landscape does — like the Turkana Basin stretching across southern Ethiopia and northern Kenya, Melillo said. Previous research has found evidence to suggest that Homo and Paranthropus coexisted there 1.5 million years ago. The new study focuses on the Afar Depression, a basin to the north of the Turkana. 'This contribution by Villmoare and colleagues demonstrates that in the Afar there was also some other species around with Homo — but it isn't Paranthropus,' Melillo said. 'Instead, they identify this 'non-Homo' genus as Australopithecus. They do a very convincing job of demonstrating why the new fossils are not Paranthropus.' The study adds to growing evidence that Australopithecus was not roaming the Afar Depression alone, she said. A mysterious coexistence When Australopithecus and Homo were alive, the Afar Region, now mostly a semidesert, had much more seasonal variation in rainfall than it does today, Reed said. Millions of years ago, the environment there was still dominated by a dry season, but it was interrupted by a brief wet season. Rivers that carried water across the landscape existed for only part of the year. Few trees grew near the river, and the environment nearby was largely wetlands and grasslands. 'We have a fossil giraffe species that was eating grass, which probably indicates they were stressed as they eat trees and bushes almost every place else,' Reed said. 'Were the hominins eating the same thing? We are trying to find out by examining isotopes in their teeth and microscopic scratches on their teeth.' Understanding whether or not Homo and Australopithecus had the same food sources could paint a portrait of how our ancient ancestors shared or competed for resources, Reed said. The team also wants to try to identify which hominin made the stone tools found at the site. At the moment it's impossible to tell exactly how the two hominins coexisted, but Reed said she is hoping that future findings will provide more answers. 'Whenever you have an exciting discovery, if you're a paleontologist, you always know that you need more information,' Reed said. 'You need more fossils. More fossils will help us tell the story of what happened to our ancestors a long time ago — but because we're the survivors we know that it happened to us.' Sign up for CNN's Wonder Theory science newsletter. Explore the universe with news on fascinating discoveries, scientific advancements and more. Solve the daily Crossword
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a day ago
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Never-before-seen cousin of Lucy might have lived at the same site as the oldest known human species, new study suggests
When you buy through links on our articles, Future and its syndication partners may earn a commission. Roughly 2.6 million-year-old fossilized teeth found in Ethiopia might belong to a previously unknown early human relative, researchers say. The teeth are from a species of Australopithecus, the genus that includes Lucy (A. afarensis). But these newly discovered teeth don't appear to belong to any known species of Australopithecus, according to a new study published in the journal Nature on Wednesday (Aug. 13). What's more, at the same site the researchers found extremely old teeth from Homo, the genus that includes modern humans (Homo sapiens). These teeth may belong to the oldest known Homo species on record, which scientists haven't yet named, the study found. These new discoveries show that at least two lineages of early hominins — a group that includes humans and our closest relatives — coexisted in the same region around 2.6 million years ago, the researchers said. Discoveries at Ledi-Geraru archaeological site The researchers found the teeth at the Ledi-Geraru archaeological site in northeastern Ethiopia, which is known for earlier groundbreaking discoveries: a 2.8 million-year-old jawbone that's the oldest known human specimen, as well as some of the oldest known stone tools made by hominins, which date to 2.6 million years ago. Paleontologists and archaeologists hypothesize that the region was an open and arid grassy plain during this period, based on grass-eating animal fossils from that time. The area offered resources Homo and Australopithecus could use, Frances Forrest, an archaeologist at Fairfield University in Connecticut who was not involved with the new research, told Live Science in an email. Grasslands and rivers would have provided water to drink, plants to eat and large animals to hunt. Related: 'Huge surprise' reveals how some humans left Africa 50,000 years ago But the unusually rich fossil record in this area could also be because of excellent preservation of remains, due to volcanic eruptions, for example — not necessarily that this was a hominin hotspot, Forrest said. Australopithecus and Homo teeth In the new study, the researchers used layers of volcanic ash above and below the newly discovered fossils to determine their age. Of the 13 teeth discovered, the team found 10 are 2.63 million years old and belonged to an unidentified species of Australopithecus, which for now the researchers are calling the Ledi-Geraru Australopithecus. Previously, researchers had found remains in the region from A. afarensis and Australopithecus garhi. But the newfound teeth look different from the teeth of those species. "It doesn't match any of these, so it could be a new species," study co-author Kaye Reed, a paleoecologist at Arizona State University, told Live Science. However, the research team hasn't officially named it as a newly identified species because the teeth don't have any especially unique features. "In the fossil record, researchers usually define a new species by finding anatomical traits that consistently differ from those of known species," Forrest said, adding that the evidence from this discovery is too limited to define a new species. The researchers also identified two teeth that are 2.59 million years old, and one that is 2.78 million years old, all belonging to the genus Homo, which Reed believes are from the same species as the oldest known Homo specimen — the jawbone discovered in Ledi-Geraru — although this hasn't been confirmed. Image 1 of 2 Study authors J. Ramón Arrowsmith and Christopher J. Campisano examine the geology of the area near the new fossils. Image 2 of 2 An aerial view of the Ledi-Geraru excavation site, home of the newly discovered fossilized teeth, and where the oldest known Homo specimen has been uncovered. The new discovery means at least three hominin species were living in this region of Ethiopia before 2.5 million years ago: the Homo and Australopithecus species these teeth belong to, as well as A. garhi. At the same time, A. africanus lived in South Africa, and Paranthropus, another hominin genus, lived in what is now Kenya, Tanzania and southern Ethiopia. This evolutionary trial-and-error within the extended hominin family is why humans' evolutionary tree is considered "bushy" rather than linear. "It has become clear over the last decade or so that during most of our evolutionary history … there have been multiple species of human relatives that existed at the same time," John Hawks, an anthropologist at the University of Wisconsin-Madison who was not involved in the new research, told Live Science. "The new paper tells us this is happening in Ethiopia … [in] a really interesting time frame, because it's maybe the earliest population of our genus Homo." Next steps The research team is now studying the enamel on the newfound teeth, as their chemistry can reveal what these species were eating. This may shed light on whether these hominins were eating the same things and competing for similar resources. "Right now, we can say very little with certainty about direct interaction between Australopithecus and Homo," Forrest said. "We know that both genera sometimes overlapped in time and space, but there is no behavioral evidence linking the two." RELATED STORIES —300,000-year-old teeth from China may be evidence that humans and Homo erectus interbred, according to new study —78,000-year-old footprints from Neanderthal man, child and toddler discovered on beach in Portugal —Stunning facial reconstructions of 'hobbit,' Neanderthal and Homo erectus bring human relatives to life Chimpanzees and gorillas live in some of the same forests, Hawks pointed out, but they're mostly geographically separated from each other, not living side by side. The fact these early hominins may have lived closer together than primates typically do now is interesting, Hawks said. "They probably weren't eating the same things," Reed noted. "But right now we don't really know." The researchers are also searching for more information and fossils at the site. "Everything we find is a piece in the puzzle of human evolution," Reed said. Human evolution quiz: What do you know about Homo sapiens?
