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Reuters
14 minutes ago
- Reuters
Florida reports 21 cases of E.coli infections linked to raw milk
Aug 4 (Reuters) - The Florida Department of Health said on Monday that there have been 21 cases of Campylobacter and E. coli infections linked to drinking raw milk in the state, including six children under 10. The state health department reported seven hospitalizations linked to the consumption of raw milk containing disease-causing bacteria from a particular farm in Northeast/Central Florida. "Sanitation practices in this farm are of particular concern due to the number of cases," the health department said. The Shiga toxin-producing E. coli and Campylobacter infections can cause diarrhea, vomiting and stomach cramps. In severe cases, they can cause kidney failure, which is of particular concern for children, the health department said. In Florida, raw milk is sold only for non-human consumption as pet or animal food, which limits sanitary regulation efforts. Containers must be clearly labeled that the raw milk is for animal consumption only. Federal health officials have warned against consuming raw milk due to the bird flu outbreak in the United States. U.S. Health Secretary Kennedy has been a proponent of raw milk.
Daily Mail
14 minutes ago
- Daily Mail
Dietitian reveals the surprising ingredient cheeseburgers need to slash calories and fat
Burgers are a quintessential summer food and perfect for at-home cookouts. But for those worrying about patties and their potential negative health consequences, a top dietitian has revealed how you can make them better for your body. New York City-based registered dietitian Dr Natalie Rizzo says her top tip for healthy burgers is to add mushrooms into the mix. 'Eating more plants is one of the best things you can do for your health, but that doesn't mean you have to ditch meat entirely,' she explains. The health expert recommends blending finely chopped mushrooms into ground beef to make a burger mix. She says the texture of mushrooms mimics meat and they also have a good umami (savory) flavor. This umami flavor in mushrooms can contribute to feelings of fullness and satisfaction, potentially aiding in weight management. On top of having a good flavor profile, Dr Rizzo said in a piece for that mushrooms are a nutrient-rich, low-calorie food. They generally only have about 15 calories per cup. Many types of mushrooms also offer unique health benefits, such as providing vitamin D and potentially aiding in cancer prevention. Mushrooms have been used by Asian doctors in the hope of treating a number of health problems for centuries. Extracts from turkey tail mushroom and shiitake mushrooms are currently approved to treat cancer in Japan and China. American doctors became attuned to the trend around the dawn of the 21st century, while a series of studies have thrust the vegetables into the spotlight in recent years. Studies have shown that five kinds of mushrooms are the most promising when it comes to protecting against cancer: shiitake, turkey tail, reishi, white cap and maitake. It is thought that the vitamins and antioxidants found in these five mushrooms could help protect against cancer by muting the effect of free radicals - molecules that cause damage to DNA and cells. These include vitamins B, D, selenium and niacin, as well as two little-known compounds called ergothioneine and lentinan. By replacing one-third of the beef in your burger patty with mushrooms, Dr Rizzo says you will benefit from the nutrients and the burgers will also contain up to one-third fewer calories, fat and sodium. Previous studies have found eating too many burgers made with red meat can start damaging your body in just three weeks because they can lead to increased risk of cardiovascular disease due to high saturated fat and sodium content. The World Cancer Research Fund recommends that people limit red meat consumption to no more than three portions per week (around 350 to 500 grams cooked weight in total), and processed meat should be eaten rarely, if at all. One hamburger contains about 21 grams of fat. Additionally, ground beef used to form the patty is high in saturated fat. Foods that are high in saturated fat are dangerous for the heart even when people do not gain weight, a 2024 study by Oxford University found. The small study, which was funded by the British Heart Foundation and presented at the European Society of Cardiology Congress in London, comprised 24 participants who were closely monitored. In the tests, one group of people were asked to follow a diet high in saturated fat eating goods such as pizza, cakes and burgers, and another group were asked to eat foods containing healthier fats - like oily fish and nuts - for up to 24 days. At the end, neither group had gained weight but those who ate more saturated fat showed a sharp deterioration in basic markers of health and had scan results linked to an increased risk of heart disease. They also had a 20 percent increase in the amount of fat stored in livers, heightening risk of type 2 diabetes and saw their levels of total and 'bad' cholesterol rise by roughly 10 percent. Nikola Srnic, the lead researcher from Oxford University, said: 'It's the type of fat, not the amount of fat, that's important. 'It is interesting how you can see such a change so quickly, within three weeks. 'The results suggest that a diet high in saturated fat may negatively change cardiovascular disease risk factors even when a person does not gain weight.'
Medical News Today
an hour ago
- Medical News Today
Miplyffa (arimoclomol)
Miplyffa is a brand-name oral capsule. It's prescribed for symptoms that affect the brain, spinal cord, and nerves in people with a rare genetic condition. Miplyffa contains the active ingredient arimoclomol. Specifically, the Food and Drug Administration (FDA) has approved Miplyffa to treat symptoms that affect the brain, spinal cord, and nerves in people with Niemann-Pick disease type C. It's prescribed for adults and children ages 2 years and detailsYou'll find key information about Miplyffa here:Drug class: heat shock protein stimulatorDrug form: oral capsuleGeneric available? noPrescription required? yesControlled substance? noMiplyffa genericMiplyffa is available only as a brand-name medication. It's not currently available in generic form.A generic drug is an exact copy of the active ingredient in a brand-name medication. Generics usually cost less than brand-name dosageThe Miplyffa dosage your doctor prescribes will depend on several factors. These include:your body weight in kilograms (kg)other medical conditions you may haveFor reference, 1 kg is about 2.2 pounds (lb).The following information describes dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your form and strengthsMiplyffa comes as an oral capsule. It's available in four strengths:47 milligrams (mg)62 mg93 mg124 mgDosage for Niemann-Pick disease type CMiplyffa is prescribed to treat symptoms that affect the brain, spinal cord, and nerves caused by Niemann-Pick disease type C. It's prescribed for adults and children ages 2 years and typical dosage of Miplyffa depends on body weight as outlined below:8 kg to 15 kg (about 17 lb to 33 lb): 47 mg three times dailymore than 15 kg to 30 kg (about 33 lb to 66 lb): 62 mg three times dailymore than 30 kg to 55 kg (about 66 lb to 121 lb): 93 mg three times dailymore than 55 kg (about 121 lb): 124 mg three times dailyYour doctor may prescribe a different dosage depending on certain factors, such as your kidney function. If you have questions about the Miplyffa dosage that's right for you, talk with your taking MiplyffaYou'll find information about key dosage issues here:When to take: You should take Miplyffa three times daily, around the same time each day. This helps keep a steady level of the drug in your body so the drug can work you miss a dose: If you miss a dose of Miplyffa, skip it. Then take your next dose at the regular Miplyffa with food: You can take Miplyffa with or without splitting, or chewing Miplyffa: If possible, Miplyffa capsules should be swallowed whole. But if you have trouble swallowing capsules, you can open them. Sprinkle the contents onto 15 milliliters (mL) of apple juice, water, or a soft food such as yogurt or applesauce. Take the mixture right away. If you use a feeding tube, you can mix the capsule contents with 20 mL of water and give the mixture through the tube. Be sure to flush the tube with 5 mL of water afterward. Length of use: Miplyffa is meant to be a long-term treatment. If you and your doctor determine that Miplyffa is safe and effective for you, you'll likely take it long of time to work: Miplyffa starts to work after your first dose. Your doctor will monitor your condition to determine how well the drug is side effectsMiplyffa can cause mild or serious side effects. The following lists contain some of the key side effects that may occur while taking Miplyffa. These lists do not include all possible side more information about the possible side effects of Miplyffa, talk with your doctor or pharmacist. They can give you tips on how to manage any side effects that may be concerning or After the Food and Drug Administration (FDA) approves a drug, it tracks and reviews side effects of the medication. Sharing your experience helps make medications safer for everyone by giving doctors and researchers more information about how the drug works in real life. If you develop a side effect while taking Miplyffa and want to tell the FDA about it, visit MedWatch or call side effectsHere is a partial list of mild side effects of Miplyffa. To learn about other mild side effects, talk with your doctor or pharmacist, or view Miplyffa's prescribing side effects of Miplyffa can include:diarrheaheadachehivesloss of appetiteseizuretremorupper or lower respiratory tract infectionweight lossMost of these side effects may go away within a few days to a couple of weeks. However, if they become more severe or don't go away, talk with your doctor or side effectsSerious side effects from Miplyffa aren't common, but they can occur. Call your doctor right away if you have serious side effects. Call 911 or your local emergency phone number if your symptoms feel life threatening or you think you're having a medical side effects can include high creatinine levels, which may affect how kidney function is REACTIONFor some people, Miplyffa can cause an allergic general, symptoms of an allergic reaction can be mild or to manageFor mild allergic reaction symptoms, such as a mild rash, call your doctor right away. They may recommend treatments to help manage your symptoms. They'll also let you know whether you should keep taking the severe allergic reaction symptoms, such as swelling or trouble breathing, call 911 or your local emergency number right away. These symptoms require immediate medical care because they can become life threatening. If you've had a serious allergic reaction to Miplyffa, your doctor may recommend a different medication usesThe following information describes Miplyffa's approved use by the Food and Drug Administration (FDA).Miplyffa for Niemann-Pick disease type CMiplyffa is approved to treat symptoms that affect the brain, spinal cord, and nerves in people with Niemann-Pick disease type C (NPC). It's prescribed for adults and children ages 2 years and is a rare genetic condition that affects how the body stores and removes cholesterol and other fats. Over time, these fats build up in the brain and other parts of the body. This can lead to worsening symptoms that may affect the brain, spinal cord, and nerves. Symptoms of NPC may include seizures and difficulty walking, balancing, speaking, or this purpose, Miplyffa is typically prescribed with miglustat (Opfolda, Yargesca, others). Together, these medications may help slow the worsening of NPC learn more about Miplyffa for NPC, talk with your and childrenMiplyffa is approved to treat NPC in children ages 2 years and learn more about Miplyffa for children with NPC, talk with your child's interactionsMiplyffa can interact with several other medications. However, the drug isn't known to interact with any supplements or taking Miplyffa, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential with medicationsHere is a list of medications that can interact with Miplyffa. This list does not contain all drugs that may interact with Miplyffa. If you have questions about drug interactions that may affect you, ask your doctor or that can interact with Miplyffa• cisplatin (Kemoplat)• cimetidine (Tagamet HB)• ipratropium (Atrovent HFA)• lamivudine (Epivir)• metformin (Glumetza)Alcohol interactionAlcohol is not known to interact with Miplyffa. If you have questions about whether it's safe to drink alcohol while taking Miplyffa, talk with your doctor or cost and savingsAs with all medications, the cost of Miplyffa can vary. The actual price you'll pay depends on your insurance plan, your location, and the pharmacy you and insurance assistance: If you need financial support to pay for Miplyffa or help understanding your insurance coverage, help is available.A program called AmplifyAssist is available for Miplyffa. For more information and to find out if you're eligible for support, call 888-668-4198 or visit the program version: Miplyffa is not available in a generic form. A generic drug is an exact copy of the active ingredient in a brand-name medication. Generics tend to cost less than brand-name drugs.»Learn more about saving money on drugsOther drugs are available that can treat Niemann-Pick disease type C. Examples include levacetylleucine (Aqneursa) and miglustat (Opfolda, Yargesca, others).Some drugs may be a better fit for you than others. If you're interested in finding an alternative to Miplyffa, talk with your doctor. They can tell you about other medications that may work well for to consider when taking Miplyffa If you can become pregnant, consider the following information about pregnancy, fertility, birth control, and and pregnancy It may not be safe to take Miplyffa during pregnancy. This is based on the results of animal studies, which don't always predict what will happen in humans. If you're planning a pregnancy or can become pregnant, talk with your doctor before taking this medication. Your doctor may suggest birth control options to use during treatment with and fertilityIn animal studies, Miplyffa decreased female and male fertility (the ability to conceive). However, animal studies don't always predict what will happen in starting Miplyffa treatment, talk with your doctor about the drug's possible effects on fertility. They can recommend whether Miplyffa is the right treatment and birth controlMiplyffa may not be safe to take during pregnancy. If you're sexually active and you or your partner can become pregnant, talk with your doctor about your birth control options while you're taking The use of binary terms such as 'male' and 'female' or 'men' and 'women' in this article reflects the language of the sources we've used. Unless otherwise noted, it's unclear whether the research we reference included participants with expansive gender females using MiplyffaDoctors may advise females who can become pregnant to use birth control during Miplyffa treatment. If you're a female taking Miplyffa, talk with your doctor about your birth control males using MiplyffaIf you're a male with a sexual partner who can become pregnant, talk with your doctor about your birth control needs during Miplyffa treatment. Miplyffa and breastfeedingIt's not known whether Miplyffa should be taken while breastfeeding. If you're currently breastfeeding or planning to do so, talk with your doctor before taking this Miplyffa worksMiplyffa's mechanism of action (how it works) is not fully understood. Miplyffa is used to treat Niemann-Pick disease type C, which is a rare genetic condition that can cause fats to build up in the body. This buildup may lead to symptoms that affect the brain, spinal cord, and nerves. Miplyffa is thought to help slow the worsening of these you have other questions bout how Miplyffa works, talk with your doctor or precautionsCertain factors or conditions could prevent your doctor from prescribing Miplyffa due to the risk of harm. These are known as contraindications. However, Miplyffa does not have any known taking Miplyffa, discuss your health history with your doctor. Miplyffa may not be suitable for you if you have specific medical conditions or other health factors. Be sure to talk with your doctor if any of the following apply to you:kidney problemsprevious allergic reaction to this or a similar drugpregnancybreastfeedingNote: For more information about the potential negative effects of Miplyffa, see the 'Miplyffa side effects' Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
