Massive Bio Recognized in Two Key Categories on CB Insights' AI Drug Research & Development Market Map
"Being recognized in two critical categories by CB Insights is a testament to the power of AI in transforming oncology care."
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CB Insights' market map highlights companies at the forefront of leveraging AI to accelerate drug discovery and development. Massive Bio's inclusion in both the 'Clinical Trial Matching' and 'Patient Recruitment' categories reflects its dual impact on streamlining clinical trial processes and enhancing patient access to cutting-edge therapies.
'Being recognized by CB Insights in two critical categories is a testament to our team's dedication to transforming oncology care,' said Selin Kurnaz, PhD, CEO and Co-Founder of Massive Bio. 'Our AI-driven platform is designed to bridge the gap between patients and clinical trials, ensuring that individuals receive the most appropriate and timely treatments available.'
Arturo Loaiza-Bonilla, MD, Co-Founder and Chief Medical Officer, added, 'This acknowledgment validates our commitment to integrating advanced AI technologies into clinical workflows. By optimizing trial matching and patient recruitment, we're not only improving operational efficiencies but also enhancing patient outcomes in oncology.'
This recognition from CB Insights follows a milestone presence at ASCO25, where Arturo Loaiza-Bonilla presented a poster session on AI-powered clinical trial matching and participated in the ASCO/ESMO Joint Session, emphasizing international collaboration in oncology innovation. In addition, Selin Kurnaz was named a PCC Wayfinder, honoring her leadership in advancing equitable access and data-driven transformation in cancer care.
Massive Bio's platform utilizes sophisticated algorithms and real-time data analytics to match cancer patients with suitable clinical trials, considering factors such as genetic profiles, treatment histories, and geographic locations. This approach has significantly increased trial enrollment rates and reduced the time required to identify eligible participants.
The company's dual recognition by CB Insights highlights its comprehensive approach to addressing challenges in clinical trial enrollment and patient engagement. As the demand for personalized cancer treatments grows, Massive Bio continues to lead in providing scalable, AI-driven solutions that connect patients with life-saving clinical trials.
About Massive Bio
Massive Bio, co-founded by , Arturo Loaiza-Bonilla, and Çağatay Çulcuoğlu, transforms the pharmaceutical value chain with AI-driven solutions. As an AI-enabled real-world data company, it streamlines the patient journey, enhances access to advanced treatment options, and optimizes clinical trials. Massive Bio collaborates with pharmaceutical companies, research organizations, and healthcare institutions worldwide. A founding member of the CancerX public-private partnership and participant in the Cancer Moonshot White House initiative, the company has received recognition from the National Cancer Institute and operates across 17 countries with a global team of over 100 employees. For more information, visit www.massivebio.com.
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International Nonproprietary Name: The International Nonproprietary Names (INN) Expert Committee of the World Health Organization selected anzutresgene autoleucel (anzu-cel) as the INN for Immatics' PRAME cell therapy, previously known as IMA203. Each INN, often called a generic name, is a distinct and globally recognized designation used to identify pharmaceutical substances or active ingredients. Second Quarter 2025 Financial Results Cash Position: Cash and cash equivalents as well as other financial assets total $560.5 million1 (€478.2 million) as of June 30, 2025, compared to $708.5 million1 (€604.5 million) as of December 31, 2024. The decrease is mainly due to ongoing research and development activities and includes unrealized foreign exchange translational losses of $41.7 million1 (€35.6 million), which do not impact the expected cash reach. Revenue: Total revenue, consisting of revenue from collaboration agreements, was $5.5 million1 (€4.7 million) for the three months ended June 30, 2025, compared to $22.0 million1 (€18.8 million) for the three months ended June 30, 2024. Research and Development Expenses: R&D expenses were $52.9 million1 (€45.1 million) for the three months ended June 30, 2025, compared to $41.3 million1 (€35.2 million) for the three months ended June 30, 2024. The increase mainly resulted from costs associated with the advancement of the product candidates in clinical trials. General and Administrative Expenses: G&A expenses were $15.0 million1 (€12.8 million) for the three months ended June 30, 2025, compared to $11.8 million1 (€10.1 million) for the three months ended June 30, 2024. Net Profit and Loss: Net loss was $82.4 million1 (€70.3 million) for the three months ended June 30, 2025, compared to a net loss of $21.1 million1 (€18.0 million) for the three months ended June 30, 2024. The increase mainly resulted from lower revenue recognized and higher unrealized non-cash foreign exchange rate losses. Full financial statements can be found in our Report on 6-K filed with the Securities and Exchange Commission (SEC) on August 13, 2025, and published on the SEC website under Global Healthcare Conference, New York (NY) – September 3 - 5, 2025 Jefferies Global Healthcare Conference, London, United Kingdom – November 17 - 20, 2025 To see the full list of events and presentations, visit: About PRAMEPRAME is a target expressed in more than 50 cancers. Immatics is the global leader in precision targeting of PRAME and has the broadest PRAME franchise with the most PRAME indications and modalities. The Immatics PRAME franchise currently includes three product candidates, two therapeutic modalities and a combination therapy that target PRAME: anzu-cel (anzutresgene autoleucel, IMA203) PRAME cell therapy, IMA203CD8 PRAME cell therapy (GEN2), IMA402 PRAME bispecific and anzu-cel in combination with Moderna's PRAME adaptive immune modulating therapy. About ImmaticsImmatics combines the discovery of true targets for cancer immunotherapies with the development of the right T cell receptors with the goal of enabling a robust and specific T cell response against these targets. This deep know-how is the foundation for our pipeline of Adoptive Cell Therapies and TCR Bispecifics as well as our partnerships with global leaders in the pharmaceutical industry. We are committed to delivering the power of T cells and to unlocking new avenues for patients in their fight against cancer. Immatics intends to use its website as a means of disclosing material non-public information. For regular updates you can also follow us on LinkedIn and Instagram. Forward-Looking StatementsCertain statements in this press release may be considered forward-looking statements. Forward-looking statements generally relate to future events or the Company's future financial or operating performance. For example, statements concerning timing of data read-outs for product candidates, the timing, outcome and design of clinical trials, the nature of clinical trials (including whether such clinical trials will be registration-enabling), the timing of IND, CTA or BLA filings, estimated market opportunities of product candidates, the Company's focus on partnerships to advance its strategy, and other metrics are forward-looking statements. In some cases, you can identify forward-looking statements by terminology such as 'may', 'should', 'expect', 'plan', 'target', 'intend', 'will', 'estimate', 'anticipate', 'believe', 'predict', 'potential' or 'continue', or the negatives of these terms or variations of them or similar terminology. Such forward-looking statements are subject to risks, uncertainties, and other factors which could cause actual results to differ materially from those expressed or implied by such forward-looking statements. These forward-looking statements are based upon estimates and assumptions that, while considered reasonable by Immatics and its management, are inherently uncertain. New risks and uncertainties may emerge from time to time, and it is not possible to predict all risks and uncertainties. Factors that may cause actual results to differ materially from current expectations include, but are not limited to, various factors beyond management's control including general economic conditions and other risks, uncertainties and factors set forth in the Company's Annual Report on Form 20-F and other filings with the Securities and Exchange Commission (SEC). Nothing in this press release should be regarded as a representation by any person that the forward-looking statements set forth herein will be achieved or that any of the contemplated results of such forward-looking statements will be achieved. You should not place undue reliance on forward-looking statements, which speak only as of the date they are made. The Company undertakes no duty to update these forward-looking statements. All the scientific and clinical data presented within this press release are – by definition prior to completion of the clinical trial and a clinical study report – preliminary in nature and subject to further quality checks including customary source data verification. For more information, please contact: MediaTrophic CommunicationsPhone: +49 151 74416179immatics@ Immatics SilversteinHead of StrategyPhone: +1 346 319-3325InvestorRelations@ Immatics N.V. and subsidiariesCondensed Consolidated Statement of Loss of Immatics N.V. Three months ended June 30,Six months ended June 30,2025 20242025 2024(Euros in thousands, except per share data)(Euros in thousands, except per share data) Revenue from collaboration agreements 4,73718,755 23,31849,024 Research and development expenses (45,106 ) (35,216 )(87,014 ) (67,324 ) General and administrative expenses (12,780 ) (10,128 )(24,847 ) (21,770 ) Other income 2225 4137 Operating result (53,127 ) (26,564 )(88,502 ) (40,033 ) Change in fair value of liabilities for warrants 133(648 )1,730395 Other financial income 4,4219,665 10,68520,580 Other financial expenses (22,776 ) (305 )(36,113 ) (515 ) Financial result (18,222 ) 8,712 (23,698 ) 20,460 Loss before taxes (71,349 ) (17,852 )(112,200 ) (19,573 ) Taxes on income 1,001(140 )1,996(660 ) Net loss (70,348 ) (17,992 )(110,204 ) (20,233 ) Net loss per share: Basic (0.58 ) (0.17 )(0.91 ) (0.20 ) Diluted (0.58 ) (0.17 )(0.91 ) (0.20 )Immatics N.V. and subsidiariesCondensed Consolidated Statement of Comprehensive Loss of Immatics N.V. Three months ended June 30,Six months ended June 30, 2025 20242025 2024 (Euros in thousands)(Euros in thousands) Net loss (70,348 ) (17,992 )(110,204 ) (20,233 ) Other comprehensive income/(loss)Items that may be reclassified subsequently to profit or loss Currency translation differences from foreign operations (5,833 ) 462 (8,544 ) 798 Total comprehensive loss for the period (76,181 ) (17,530 )(118,748 ) (19,435 ) Immatics N.V. and subsidiariesCondensed Consolidated Statement of Financial Position of Immatics N.V. 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Six months ended June 30, 2025 2024 (Euros in thousands)Cash flows from operating activities Net loss (110,204 ) (20,233 ) Taxes on income (1,996 ) 660Loss before tax (112,200 ) (19,573 ) Adjustments for: Interest income (9,719 ) (12,660 ) Depreciation and amortization 6,1666,116Interest expenses 493420Equity-settled share-based payment 8,4718,605Net foreign exchange differences and expected credit losses 34,241(7,723 ) Change in fair value of liabilities for warrants (1,730 ) (395 ) Gains from disposal of fixed assets 401Changes in: Decrease in accounts receivables 3,8941,283(Increase)/decrease in other assets (277 ) 766 Decrease in deferred revenue, accounts payables and other liabilities (15,534 ) (48,493 ) Interest received 18,0128,260Interest paid (493 ) (420 ) Income tax paid (5,445 ) (2,012 ) Income tax refunded 820— Net cash used in operating activities (73,261 ) (65,825 ) Cash flows from investing activities Payments for property, plant and equipment (4,503 ) (11,797 ) Payments for intangible assets (190 ) (148 ) Proceeds from disposal of property, plant and equipment 47— Payments for investments classified in Other financial assets (280,651 ) (356,596 ) Proceeds from maturity of investments classified in Other financial assets 396,353196,548Net cash provided by/(used in) investing activities 111,056(171,993 ) Cash flows from financing activities Net proceeds from issuance of shares to equity holders 9174,476Payments of lease liabilities (1,473 ) (397 ) Net cash provided by/(used in) financing activities (1,464 ) 174,079Net increase/(decrease) in cash and cash equivalents 36,331(63,739 ) Cash and cash equivalents at the beginning of the period 236,748218,472Effects of exchange rate changes and expected credit losses on cash and cash equivalents (16,444 ) 3,410Cash and cash equivalents at the end of the period 256,635158,143 Immatics N.V. and subsidiariesCondensed Consolidated Statement of Changes in Shareholders' Equity of Immatics N.V. (Euros in thousands)Sharecapital Sharepremium Accumulateddeficit Otherreserves Totalshare-holders'equityBalance as of January 1, 2024 847823,166(604,759 ) (1,636 ) 217,618Other comprehensive income —— —798798Net loss ——(20,233 ) —(20,233 ) Comprehensive income/(loss) for the period ——(20,233 ) 798(19,435 ) Equity-settled share-based compensation —8,605——8,605Share options exercised 11,036——1,037Issue of share capital – net of transaction costs 183173,257——173,440Balance as of June 30, 2024 1,0311,006,064(624,992 ) (838 ) 381,265Balance as of January 1, 2025 1,2161,162,136(589,541 ) 1,031574,842Other comprehensive loss ———(8,544 ) (8,544 ) Net loss ——(110,204 ) —(110,204 ) Comprehensive loss for the period ——(110,204 ) (8,544 ) (118,748 ) Equity-settled share-based compensation —8,471——8,471Share options exercised —9——9 Balance as of June 30, 2025 1,2161,170,616(699,745 ) (7,513 ) 464,574 1 All amounts translated using the exchange rate published by the European Central Bank in effect as of June 30, 2025 (1 EUR = 1.172 USD).2 Refers to PRAME+/HLA-A*02:01+ patients in the US and EU5 in 2025; Source: Clarivate Disease Landscape and Forecast Attachment PDF VersionError in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
