logo
Local girl holds fundraiser for St. Jude in hopes of helping kids her age beat cancer

Local girl holds fundraiser for St. Jude in hopes of helping kids her age beat cancer

Yahoo19-05-2025

One local 11-year-old is on a mission to help others her age battle and defeat cancer.
Keira Totleben held a fundraiser to support St. Jude Children's Research Hospital on Saturday.
Lake Erie Ale Trail hosts 7th annual Beer Coaster fundraising event
Totleben organized a Chinese action with over 40 baskets, as well as a bake sale.
Several local businesses contributed to the Chinese auction, which helped her get closer to her goal.
'It's just amazing' — Penn State Behrend helps community with annual rummage sale
'You can accomplish anything if you put your mind to it,' said Totleben. 'My goal this time is $5,000.'
If you would like to donate, click here.
Copyright 2025 Nexstar Media, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.

Orange background

Try Our AI Features

Explore what Daily8 AI can do for you:

Comments

No comments yet...

Related Articles

Chinese researchers charged with smuggling
Chinese researchers charged with smuggling

CNN

time4 hours ago

  • CNN

Chinese researchers charged with smuggling

Chinese researchers charged with smuggling Two Chinese researchers have been charged with smuggling a "potential agroterrorism weapon" into the US in a wad of tissues, according to an FBI affidavit. CNN's Max Foster explains how laboratory testing discovered a sample containing a DNA sequence with the potential to cause a fungal disease that could decimate crops, and impact human health. 01:10 - Source: CNN Record rain floods Mexico City, traps people Mexico City was hit with record rainfall that didn't relent for more than five hours Monday night, marking the heaviest rain since 2017, according to water management officials. CNN's Valeria León walks a flooded avenue of the nation's capital after emergency crews worked through the night to rescue several trapped drivers. 00:43 - Source: CNN Gaza aid distribution turns deadly for third consecutive day For a third consecutive day, Palestinians came under fire while trying to receive aid from a distribution site in Gaza. According to the Palestinian Ministry of Health and Nasser hospital, at least 27 people were killed and dozens injured on June 3. 00:56 - Source: CNN Analysis: Why Ukraine's drone attack on Russia just changed the world CNN's Jim Sciutto explains why Ukraine's large-scale drone attack on Russian air bases thousands of miles behind the front lines struck fear into the heart of every global superpower 01:05 - Source: CNN Tomatoes fly at Colombia's largest food fight Around 20,000 revellers gathered in Sutamarchán, Colombia, to throw over 45 tonnes of tomatoes at each other. The Gran Tomatina festival, now in its 15th year, is hosted to celebrate the economy of Sutamarchán, which is centred around tomato production. Mayor Miguel Andrés Rodríguez said "between 70 and 80 percent of families [in Sutamarchán] live off tomatoes. This is a tribute to them." The festival uses tomatoes which are overripe, or otherwise not suitable for consumption. 00:30 - Source: CNN Palestinians shot dead near Gaza aid hub The Palestinian health ministry, hospital officials and multiple eyewitnesses say deadly gunfire killed dozens of Palestinians near an aid distribution site in Gaza on Sunday, with Israel's military denying that its troops fired 'within or near' the aid site. CNN Jerusalem correspondent Jeremy Diamond brings you up to speed on what we know about the weekend chaos. 02:31 - Source: CNN Palestinians describe deadly shooting near aid center in Gaza CNN spoke to multiple witnesses who recounted the deadly chaos that unfolded near a US-backed aid center in southern Gaza after more than 30 Palestinians were killed and dozens injured on Sunday, according to the Palestinian Ministry of Health. The health ministry blamed the Israeli military for the deaths while other witnesses claimed that local security personnel had also opened fire. Gaza Humanitarian Foundation, which runs the aid center, said there had been no gunfire at the site and Israel Defense Forces denied firing on civilians at or close to the site, calling such accusations 'false reports.' 00:55 - Source: CNN Palestinian UN envoy breaks down talking about Gaza's children The Palestinian ambassador to the UN made an emotional address, saying more than 1,300 children have been killed in Gaza since Israel ended the ceasefire in March. 01:19 - Source: CNN Political candidate wears body armor daily CNN's David Culver met César Gutiérrez Priego as he was readying to campaign for office in Mexico City. Gutiérrez Priego, who is running for a seat on the Supreme Court in Mexico, shows Culver the safety precautions he takes with political violence in Mexico at an all-time high. See Culver's full reporting on CNN. 00:53 - Source: CNN Harvard students and faculty speak out against Trump Harvard students and faculty spoke to CNN ahead of commencement as Donald Trump said the university should cap foreign enrollment. The Trump administration has recently sought to cancel $100 million in contracts with the school. 02:03 - Source: CNN Palestinians desperate for food rush US-backed aid site Scores of people rushed over fencing and through barricades in southern Gaza on the first day a US-Israeli-backed aid site was opened. CNN's Jeremy Diamond explains the desperate humanitarian situation that remains in the region. 01:22 - Source: CNN Journalists spit on at Jerusalem Day flag march Ultra-nationalist Israeli Jews chanted anti-Arab slogans as they marched through Jerusalem's Old City to mark Jerusalem Day. CNN's Oren Liebermann describes heavy police presence on the ground. Members of the crowd were seen spitting on journalists, including a CNN producer. 01:50 - Source: CNN Finland's president responds to Russian military activity along border CNN's Erin Burnett speaks with Finland's President Alexander Stubb about his country ramping up its military to deter potential Russian aggression. 02:16 - Source: CNN King Charles stresses Canada's 'self determination' amid pressure from US King Charles III delivered the ceremonial Speech from the Throne in the Canadian Senate. The address marks only the second time in Canadian history that the reigning sovereign has opened parliament, and the third time that the British monarch has delivered the address. 00:42 - Source: CNN Huge ship refloated after nearly crashing into house A larger container ship has been refloated after nearly crashing into a house in Norway. According to local police, the navigator had fallen asleep at the helm. 00:42 - Source: CNN Vehicle plows into crowd in Liverpool Police in the United Kingdom say a man has been arrested after a car plowed into Liverpool fans celebrating during the soccer club's Premier League trophy parade. 01:14 - Source: CNN Iran's Foreign Ministry on progress of Iran-US talks Iran's Foreign Ministry spokesperson Esmaeil Baqaei gave an exclusive interview to CNN's Fred Pleitgen on the progress of continuing nuclear talks with the US. Baqaei told CNN that any attempt by the Trump administration to 'deprive' Iranians of their right to nuclear energy would be 'very problematic'. But he also said that there were many ways to come to a compromise. Iran and the United States concluded a fifth round of talks in Rome on Friday. 01:16 - Source: CNN Video of President Macron's wife 'pushing' him goes viral A video of French President Macron's wife pushing him as they disembarked a flight has caught the attention of Russian trolls after going viral. While Macron himself tried to downplay the video saying it merely showed a couple 'bickering,' it's not the first time Russian troll accounts and state media outlets have tried to use videos of the French president to spread disinformation. CNN's Saskya Vandoorne has more. 01:35 - Source: CNN

MLTX Stock Gains 18% as Merck Reportedly Eyes Buyout
MLTX Stock Gains 18% as Merck Reportedly Eyes Buyout

Yahoo

time5 hours ago

  • Yahoo

MLTX Stock Gains 18% as Merck Reportedly Eyes Buyout

Shares of small-biotech MoonLake Immunotherapeutics MLTX rose 18% yesterday following a report issued by the Financial Times (FT), which stated that pharma giant Merck MRK is interested in acquiring the company. Per the article, Merck had submitted a non-binding offer for MoonLake earlier this year in a deal valued at more than $3 billion. Though this offer was rejected, the FT stated that the talks could be revived and other suitors may express interest in acquiring MLTX. Both Merck and MoonLake have declined to comment on the rumor. Swiss-based MoonLake Immunotherapeutics is a clinical-stage company developing its lead pipeline asset, sonelokimab, for the treatment of inflammatory diseases. The drug is a novel nanobody therapy being developed in late-stage studies for hidradenitis suppurativa (HS) and psoriatic arthritis (PsA) indications. Topline data from the HS study is expected around September 2025. MoonLake is also developing sonelokimab for other indications in dermatology and rheumatology, including palmo-plantar pustulosis (PPP) and axial spondyloarthritis (axSpA). Year to date, the stock has lost 10% compared with the industry's 4% decline. Image Source: Zacks Investment Research The idea behind the deal is clear — Merck aims to diversify its current revenue base, which has become highly dependent on Keytruda. In 2024, the company generated nearly 46% of its total revenues from the drug's sales. With concerns over Keytruda's potential loss of exclusivity (LOE) after 2028, MRK remains under pressure from the investor community to pursue deals for new drugs that could help reduce its dependence on a single product for growth. In the past year, Merck has been tapping Chinese biotechs for licensing deals. Toward the end of last year, the company struck multi-billion-dollar deals with Hansoh Pharma, LaNova Medicines and Hengrui Pharma. While the Hansoh deal added the investigational oral GLP-1 receptor agonist HS-10535 to Merck's pipeline, the LaNova deal added the experimental bispecific VEGF/PD-1 antibody LM-299. With the Hengrui Pharma deal, Merck acquired rights to an investigational oral small-molecule lipoprotein(a) inhibitor, HRS-5346. While broader macroeconomic concerns — including Trump-era tariffs and leadership shifts at the FDA — have weighed on deal-making in 2025, Big Pharma continues to pursue strategic assets in key growth areas. This week, Sanofi SNY announced a $9.5 billion acquisition of Blueprint Medicines to strengthen its immunology pipeline and reduce reliance on blockbuster drug Dupixent. Through this transaction, Sanofi intends to add Ayvakit — an inhibitor of KIT and PDGFRA proteins with growing commercial traction — and several early-stage pipeline assets focused on systemic mastocytosis (SM). Sanofi expects to close this deal in the third quarter of 2025. In parallel, Bristol Myers Squibb BMY signed a co-development and commercialization agreement with BioNTech for BNT327, an investigational bispecific antibody targeting PD-L1 and VEGF. The deal gives Bristol Myers access to a promising oncology candidate across multiple tumor types, aligning with its strategy to offset revenue declines from legacy brands. These transactions highlight the industry's ongoing interest in targeted immunology and oncology platforms — the same areas MoonLake's sonelokimab is exploring. Merck's rumored pursuit of MoonLake fits this trend, signaling that small biotechs with promising assets remain top M&A targets for Big Pharma. MoonLake Immunotherapeutics price | MoonLake Immunotherapeutics Quote MoonLake currently carries a Zacks Rank #3 (Hold). You can see the complete list of today's Zacks #1 Rank (Strong Buy) stocks here. Want the latest recommendations from Zacks Investment Research? Today, you can download 7 Best Stocks for the Next 30 Days. Click to get this free report Sanofi (SNY) : Free Stock Analysis Report Bristol Myers Squibb Company (BMY) : Free Stock Analysis Report Merck & Co., Inc. (MRK) : Free Stock Analysis Report MoonLake Immunotherapeutics (MLTX) : Free Stock Analysis Report This article originally published on Zacks Investment Research ( Zacks Investment Research

What to know about Fusarium graminearum, the biological pathogen allegedly smuggled into the US

time8 hours ago

What to know about Fusarium graminearum, the biological pathogen allegedly smuggled into the US

The biological pathogen federal authorities accuse two Chinese nationals of smuggling into the U.S. can be concerning for farming communities but was not likely an act of "agroterrorism," according to plant pathology experts. Two citizens of the People's Republic of China -- Yunqing Jian, 33, and Zunyong Liu, 34 -- were arrested for allegedly bringing a fungus called Fusarium graminearum, a plant pathogen, into the U.S. through the Detroit Metropolitan Airport, according to the U.S. Department of Justice. Jian received Chinese government funding for her work on this pathogen in China and apparently intended to bring it to a laboratory at the University of Michigan, according to a criminal complaint filed in the Eastern District of Michigan. Jian's electronics also contained information describing her membership in and loyalty to the Chinese Communist Party, the indictment alleges. Liu, Jian's boyfriend, works at a Chinese university where he conducts research on the same pathogen, according to the Justice Department. Federal prosecutors claim that "scientific literature classifies [the pathogen] as a potential agroterrorism weapon," emphasizing that it is the "of the gravest national security concern." But the pathogen, while a concern for the agricultural industry, is not necessarily among the most significant threats the industry faces, plant pathology experts told ABC News. Breakouts of Fusarium graminearum infections already naturally occur in dozens of U.S. states -- basically any state that produces wheat and barley -- and has been established in the U.S. for at least 125 years, Caitlyn Allen, a professor emeritus of plant pathology at the University of Wisconsin-Madison, told ABC News. In addition, the U.S. Department of Agriculture keeps a list of potential agroterrorism agents, and Fusarium graminearum is not on that list, Allen said. "We're not talking about something that just got imported from China," Allen said. "People should not be freaking out." Fusarium graminearum is not at the top of the list of concerning pathogens, Gary Bergstrom, a professor emeritus of plant pathology, told ABC News. "Compared to some other things, I don't think the risk is as high," he said. "It's not zero, but it certainly wouldn't be as much concern as the accidental or otherwise introduction of some serious diseases that we don't have now." In order to be considered an agroterrorism threat, prosecutors would have to determine that the Fusarium graminearum samples are more aggressive than local strains, perhaps have different mycotoxin production abilities or more resistance to some of the tools used in the U.S., Bergstrom said. From a research perspective, scientists are "well-versed" in Fusarium graminearum, Paul Esker, a professor of plant pathology and epidemiology at Penn State University, told ABC News. "It's one of the ones that would be at the lower end of the spectrum for risk," Esker said. "We have the tools to manage it." Mitigating the threat of the toxic fungus The biggest group of plant pathogens are fungi, and Fusarium graminearum is in the same general group as yeast, used to make beer or bread, Allen said. The spores of the fungus can infect wheat and barley heads and get into the seeds, where it can multiply. Agricultural industries have already been meeting to prepare for the threat of Fusarium graminearum, as it usually occurs for wheat and barley at this time of year and for corn later in the year, said Esker, who just attended one such meeting on Tuesday. This time of year is when the winter small-grain crops, such as wheat and barley, would be impacted, Esker said. Later in the year, the concern of Fusarium graminearum moves to corn, Esker said. The sample confiscated by authorities was likely headed to the lab at the University of Michigan that studies how plants resist disease, Allen said, adding that the USDA spends "quite a bit of money every year" on wheat and barley research. "One of the most useful ways of solving disease problems on our crops is to breed crops that are resistant to the disease," she said, adding that it eliminates the need for fungicides. "Humans have been doing this for as long as we've been growing plants." What is head blight? Although the plant pathogen experts hypothesize that the motive for bringing the sample into the U.S. was not likely nefarious, they caution that the impacts from the fungus can still present a major threat to U.S. crops. "Fusarium head blight is already a major threat or a major problem for farmers who are growing wheat and barley in the United States now," Allen said. "It's one of the most important diseases of these crops in terms of current, existing losses." The noxious fungus causes "head blight," a disease of wheat, barley, maize and rice, and is responsible for billions of dollars in economic losses worldwide each year, prosecutors said. The toxins can cause vomiting, liver damage and reproductive defects in humans and livestock, prosectors said. The economic loss is felt by farmers who can't sell their commodity, Bergstrom said. In the 1990s, a series of epidemics in the upper Midwest caused a billion-dollar loss over a number of years, he said. The disease is of worldwide importance as well, with documented cases occurring in North and South America, Europe and China, Bergstrom said. Since then, monitoring programs have been put in place to mitigate the impacts of Fusarium graminearum on crops, Esker said. The fungus can produce a poison called a mycotoxin or a fungus toxin -- sometimes referred to as the "vomit toxin" because of the negative impacts it can have on the digestive symptoms of humans and animals, Bergstrom said. "Plants get sick just like people, and this particular disease that we're talking about, Fusarium, head blight, is a big problem on wheat and barley and some other grains all around the world," Allen said. The USDA maintains a wide set of rules to regulate pathogens, the experts said. In order to be granted an Animal and Plant Health Inspection Service permit from the USDA to bring a foreign strain into the country, researchers must provide background information on the strain, explain the thought process on whether they might represent a threat to local agriculture and human health, and lay out the plan for containing the pathogen, Bergstrom said. Even strains from other states within the U.S. must undergo the same process, Bergstrom said. Strains from outside the U.S. undergo more scrutiny, including inspection of the researchers' laboratories, Esker said. "That is a very sound policy, good science," Bergstrom said. It is unclear whether Jian and Liu had such permits. A case of 'bad judgment?' Plants pathogens most commonly have been moved around by accident by humans, Allen said. The occurrence of Fusarium graminearum is strongly impacted by weather conditions -- especially excess moisture, the experts said. "If the weather is really dry, I don't expect to see the disease," Esker said. Allen believes the incident is not so much smuggling but a case of "bad judgment" by passionate researchers. "I'm a biologist, right? But I'm also a biologist who has trained dozens of young scientists over my career," she said. The Justice Department press release does not detail when the alleged smuggling took place. Jian and Liu were charged with conspiracy, smuggling goods into the United States, false statements and visa fraud, U.S. attorney Jerome F. Gorgon, Jr. announced on Tuesday.

DOWNLOAD THE APP

Get Started Now: Download the App

Ready to dive into the world of global news and events? Download our app today from your preferred app store and start exploring.
app-storeplay-store