
How Many Lives Did Covid-19 Vaccines Save? New Global Study Reveals The Numbers
According to the research, 82% of the lives saved involved individuals who had received the vaccine before being infected by the coronavirus
A new international study has revealed that Covid-19 vaccines saved more than 25 lakh lives between 2020 and 2024, highlighting the profound global impact of mass immunisation efforts during the pandemic.
The study, published in the JAMA Health Forum, was jointly conducted by researchers from Universita Cattolica in Italy and Stanford University in the US. It estimates that around 25.33 lakh lives were spared due to vaccination, with one death averted for every 5,400 doses administered.
Covid-19 first emerged in Wuhan, China, in late 2019 and swept across the globe within months, triggering unprecedented health, economic, and social crises. In response, scientists raced to develop vaccines, and by the end of 2020, several versions were rolled out worldwide. Billions received two primary doses, with many also taking booster shots.
While questions were occasionally raised about the vaccine's long-term effects, particularly concerning heart-related issues, health experts repeatedly dismissed such claims, maintaining that the benefits far outweighed any rare side effects. The new study offers quantitative backing to those assertions.
Elderly Benefited Most
The researchers found the vaccine's impact was most significant among those aged 60 and above. In this age group, the vaccine prevented 90% of potential deaths. Of the estimated 1.48 crore life-years saved globally, 76% were among the elderly.
Moreover, 82% of the lives saved involved individuals who had received the vaccine before being infected by the virus. The protection was particularly evident during the Omicron wave, a highly infectious phase of the pandemic that alone accounted for 57% of the prevented deaths.
Limited Impact on Children and Youth
In contrast, the benefit of vaccination among children and young adults was marginal, largely due to their lower baseline risk of death from Covid-19. For individuals aged 0 to 19, the number of lives saved was just 0.01%, while life-years saved stood at 0.1%. For those aged 20 to 29, deaths prevented amounted to 0.07%, with 0.3% life-years gained.
Global Data, Comprehensive Scope
The study was led by Professor Stefania Boccia from Universita Cattolica, in collaboration with Dr Angelo Maria Pezzullo and Dr Antonio Christiano, both affiliated with Stanford University under a European research initiative.
Their analysis drew on global data concerning Covid-19 infections, mortality, and vaccine distribution. Using statistical modelling, the team estimated how many more people might have died in a scenario without vaccines.
What sets this study apart is its scale and scope. It is the first global research effort covering the full timeline of the pandemic – from the early days in 2020 through to 2024. It not only compares outcomes among vaccinated and unvaccinated populations but also measures the difference in impact across different virus variants, especially before and after Omicron emerged.
Beyond deaths prevented, the research also sheds light on the concept of 'life-years saved", a measure that considers not just whether a life was saved, but how many more years that person might live. This adds further depth to understanding the vaccine's role in mitigating the Covid-19 pandemic's toll.
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First Published:
July 29, 2025, 15:03 IST
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