Best Melatonin Supplements of 2025
Anyone who struggles with sleep knows how frustrating it is to wake up feeling drained. It can leave you frustrated and affect your entire day. Thankfully, there are easy ways to fix your sleep cycle, and taking melatonin supplements is one of them.
Melatonin is a natural hormone in our brains, but it can also be taken at night as a supplement to help you sleep. Taking Melatonin is a way to send a signal from your brain to your body that it's time to hit the hay. The artificial melatonin in the supplement mimics the natural melatonin production in our brains when it gets dark out. It's a great option if you prefer to stay away from traditional prescription sleep medicine since it's a natural sleep aid. Melatonin may also help with other issues, including reducing high blood pressure. There are a ton of Melatonin supplements on the market, so how do you choose the best melatonin supplement for you? It's prudent to take a look at the melatonin content of the supplement you're considering before you make a purchase.
I don't have to tell you that sleep is essential for a healthy, functioning human being. If you're looking to improve your sleep quality and need a little extra help, you've got options. There are plenty of natural supplements that can help you chill out and get to sleep faster, read below to find out which are the best ones.
Typical melatonin doses are between 1 and 5 milligrams, although some products go as high as 20 mg. Experts at the Cleveland Clinic recommend trying 1 mg of melatonin for a whole week, then upping the dose by 1 mg each following week. Stop once you get to 10 mg (do not exceed 10 mg) or until the time it takes for you to fall asleep has decreased. Talk to your doctor about any dosage concerns.
Best Magnesium Supplements
See at Cnet
Here are the best melatonin supplements on the market, chosen by our vitamin experts.
Nature Made is one of the best vitamin supplement brands on the market, if not the best. All of its supplements are USP-verified, meaning that the products and facilities have been tested for toxins and contaminants and that the label is correct. Nature Made Melatonin tablets contain 5 mg of melatonin and 80 mg of calcium (as dibasic calcium phosphate), about only 6% of the daily recommended value of calcium. If you already take a multivitamin with calcium, this shouldn't interfere. In addition, one tablet also contains sodium starch glycolate, magnesium stearate and croscarmellose sodium. Nature Made is free of added colors, preservatives, artificial flavors and gluten. Take one tablet about an hour before you go to bed. One bottle will last about 90 days.
See at Walmart
Nature's Bounty has over 50 years of experience in the supplements industry. The company is known for being affordable and accessible. The tablets in a bottle of Nature's Bounty's Melatonin are double-layered, meaning that the first layer of 2.5 mg of melatonin is fast-acting. The second layer of an added 2.5 mg of melatonin is intended for extended release. In addition to the melatonin, one tablet contains dicalcium phosphate, vegetable cellulose and less than 2% silica, triacetin, vegetable juice color, vegetable magnesium stearate and vegetable stearic acid. Nature Bounty's supplements are non-GMO and contain no artificial flavors, sweeteners, preservatives, sugar, starch, milk, soy, sodium, gluten, wheat, yeast or fish. Take one tablet at bedtime. One bottle will last for about 60 nights.
See at Amazon
Olly consistently produces great-tasting gummy vitamins. If you don't like swallowing pills with an aftertaste, gummy supplements may be for you. Olly Sleep gummies are unique on this list because they don't just contain melatonin. Each serving size of two gummies contains 15 calories, 3 grams of carbohydrates, 2 g of added sugar, 1 g of protein, 100 mg of L-Theanine, 3 mg of melatonin, 17 mg of chamomile extract, 17 mg of passionflower extract and 16 mg of lemon balm extract. Other ingredients include glucose syrup, beet sugar, water, gelatin, natural flavors, citric acid, coloring (from blueberry and carrot juices), pectin, vegetable oil and carnauba wax. They're processed in a facility that makes products that may contain soy, egg, peanuts, tree nuts, milk, fish, shellfish and wheat. The gummies are blackberry-flavored, gluten-free and contain no artificial flavors. Take two gummies 30 minutes before bed. No water or food required.
See at Walmart
Natrol is one of the most popular melatonin brands. One bottle of Natrol contains 100 tablets, enough for 100 nights. The fast-dissolving tablets don't require any water. One serving contains 10 mg of melatonin and other added ingredients such as dextrose, microcrystalline cellulose, cellulose gum, crospovidone, maltodextrin, glyceryl behenate, sucrose esters, gum acacia, beetroot powder, silicon dioxide, sucralose and artificial flavor. The tablets are free of milk, egg, fish, shellfish, tree nuts, peanuts, soy, yeast and preservatives. This is the exact melatonin supplement that I sometimes use before bed. The only reason why these supplements aren't the best overall is that they may not be for everyone. The flavor is similar to children's cherry cough syrup, so I make sure to always brush my teeth after taking one tablet. Natrol does offer another citrus flavor.
See at Amazon
Thorne is a well-known personalized supplement subscription brand. Thorne is popular with athletes because some of their supplements are NSF-certified for sports. You know what you are putting in your body from looking at the label. Thorne Melatonin contains 3 mg of melatonin and other ingredients including microcrystalline cellulose, hypromellose (derived from cellulose) capsule, calcium laurate and silicon dioxide. The capsules are free of artificial flavors, gluten, dairy and soy. This vegan supplement is to be taken at bedtime. One bottle will last about 60 nights.
See at Amazon
Liquid supplements are great for anyone who dislikes swallowing pills or artificial flavors of gummy vitamins. Now Liquid Melatonin comes in a pack of two 2.0 fluid-ounce bottles and requires about 20 drops a serving. Each bottle contains about 60 servings. The lower dose of 3 mg may require a second serving before bed. In addition to melatonin, the supplement also contains water, vegetable glycerin, fructose, xylitol (which is very harmful to pets so keep out of reach), organic cane alcohol (6%), natural orange extract (citrus sinensis), natural flavors, potassium sorbate (as preservative), citric acid, malic acid and natural lemon oil. This liquid supplement is free of gluten, soy, milk, egg, fish or shellfish ingredients. At bedtime, take the drops directly, or you can add them to your favorite beverage. The flavor is citrusy, but reviewers have described the taste as unpleasant. Drinking something afterward is recommended.
See at Amazon
Keep these factors in mind when searching for the best melatonin supplements for sleep.
You don't want anything unnecessary added to your melatonin supplements, such as fillers or extra sugar. Always study the ingredients in any vitamin supplement, and speak with your doctor before starting any supplements.
The amount of melatonin in your supplement can have a direct effect on how fast it takes you to fall asleep. 3 mg is the lowest dose of melatonin that will still help you fall asleep. 10 mg is the highest dose, and you shouldn't go any higher than that.
The serving size directly affects how long a bottle of melatonin will last you. Even if you have a product with 50 gummies, if you have to take two gummies at night, this will only last you 25 days.
Melatonin can come in tablet, capsule, gummy or liquid form. You should look for a form that fits your needs. For example, if you don't want extra sugar in your vitamins, don't buy gummy vitamins. If you don't like swallowing pills, gummy vitamins may be the best option.
Dietary supplements aren't regulated by the FDA, but there are a few verifications you can check for that will help you tell if the product you're buying is safe to use.
Those verifications include:
National Sanitation Foundation: This ensures standards set for the facility are met.
United States Pharmacopeia: A nonprofit that sets standards for dietary supplements.
Consumer Lab: Private company tests supplements for accuracy of ingredient identity, content and purity.
Dietary Supplement Verification: This program that ensures any product with a USP-verified label contains accurate, pure ingredients and has been manufactured using Good Manufacturing Practices.
All supplements on this list are 100% drug-free. They were chosen by my personal experience of taking melatonin supplements and my expertise in vitamin brands, pricing, ingredients and verification knowledge.
Melatonin is a naturally occurring hormone in the brain. It helps our circadian rhythm tell us it is time to sleep when we're exposed to darkness.
There are some negative potential effects of melatonin to be aware of with these supplements. These include waking up groggy, headaches, dizziness, nausea and drowsiness. Always speak with your doctor before starting any supplements, such as melatonin. They can help you determine the correct dosage.
Yes, melatonin works by making you sleepy around bedtime. The supplement mimics the naturally occurring hormone in our brains that tells our body it is time to fall asleep. In addition, melatonin can also make you dizzy or drowsy.

Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles
Yahoo
7 hours ago
- Yahoo
This Rare 'Silent' Cancer Has Quadrupled Among Millennials
A new study, published this week in the Annals of Internal Medicine, found that a rare form of cancer – appendix cancer, or appendiceal adenocarcinoma – is as much as three times as common among Gen X, born between 1965 and 1980, as it is among those born in the '40s. However, for older millennials who were born in the '80s (millennials were born between 1981-1996), the rates were more than four times higher. The Christie NHS Foundation Trust explains it accounts for 0.4% of all cancers of the bowel; it's a rare condition. But what is appendix cancer, how do you spot it, and why might it be on the rise? Appendiceal adenocarcinoma, the most common form of appendix cancer, can often develop 'without developing symptoms,' the Cleveland Clinic shares. Because it can be so hard to spot, it is sometimes described as a 'silent' cancer in its early stages. Often, people only notice signs when the tumours have spread; the NHS say that it is often only spotted during surgery. Some symptoms that may occur, however, include: Appendicitis Bloating A buildup of fluid in your abdomen An increased waist size Abdominal or pelvic pain. Changes in bowel habits (including diarrhoea) Nausea and vomiting Feeling full soon after you start eating. Speak to your GP immediately if you notice signs of appendix cancer. This study did not seek to find out why different generations have different rates of appendix cancer. But it is not the only cancer which has followed a similar generational pattern – bowel and breast cancer, for instance, are both affecting more and more young people while rates among older people stay roughly stable. Speaking to the New York Times, gastroenterologist and colon cancer expert Dr Andrew T. Chan, who was not involved in the study, suggested that some changes to our diet over time might be responsible for the uptick in bowel cancers. But it is hard to say more about appendix cancer, which is already a poorly understood condition. Cancer expert Professor Andreana Holowaty told the publication that the rise does not seem to be caused by an increase in diagnoses, however, not least because the disease is so hard to spot. 'Similar trends have been reported for other gastrointestinal cancers, suggestive of a potential shared cause contributing to this increasing cancer burden across generations,' the paper reads. Scientists' Bowel Cancer Breakthrough 'Pivotal' For Future Treatment These 3 Diet Changes May Reduce Your Bowel Cancer Risk By 47% The Nutrient Linked To Lower Cancer, Heart Disease, And Dementia Risk
Yahoo
10 hours ago
- Yahoo
Lisata Therapeutics to Present at the 2025 BIO International Convention
BASKING RIDGE, N.J., June 11, 2025 (GLOBE NEWSWIRE) -- Lisata Therapeutics, Inc. (Nasdaq: LSTA) ('Lisata' or the 'Company'), a clinical-stage pharmaceutical company developing innovative therapies for the treatment of advanced solid tumors and other serious diseases, today announced that David J. Mazzo, Ph.D., President and Chief Executive Officer of Lisata, will present a corporate overview at the upcoming 2025 BIO International Convention taking place in Boston, MA from June 16 – 19, 2025. Dr. Mazzo's presentation is scheduled for Tuesday, June 17th at 11:15 a.m. Eastern Time in Room 153A. To register for the conference and schedule a one-on-one meeting with Lisata's management, please visit About Lisata Therapeutics Lisata Therapeutics is a clinical-stage pharmaceutical company dedicated to the discovery, development and commercialization of innovative therapies for the treatment of advanced solid tumors and other major diseases. Lisata's cyclic peptide product candidate, certepetide, is an investigational drug designed to activate a novel uptake pathway that allows co-administered or tethered anti-cancer drugs to selectively target and penetrate solid tumors more effectively. Lisata has already established noteworthy commercial and R&D partnerships based on its CendR Platform® technology. The Company expects to announce numerous milestones over the next 1.5 years and believes that its projected capital will fund operations into the third quarter of 2026, encompassing anticipated data milestones from its ongoing and planned clinical trials. Learn more about certepetide's mechanism of action in our short film. For more information on the Company, please visit Contact: Investors:Lisata TherapeuticsJohn MendittoVice President, Investor Relations and Corporate CommunicationsPhone: 908-842-0084Email: jmenditto@ Media:ICR HealthcareElizabeth ColemanAccount SupervisorPhone: 203-682-4783Email: This press release was published by a CLEAR® Verified in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data


Medscape
12 hours ago
- Medscape
Under Fire, Cleveland Clinic Backtracks on Copay Mandate
Faced with an uproar from outraged community leaders, the Cleveland Clinic has pulled back on its plan to refuse outpatient treatment to privately insured patients unless they pay copays before appointments. Now, patients with commercial insurance or Medicare Advantage coverage will be offered a new 0% interest payment plan if they can't pay their outpatient copays, the health system announced 3 days before the new requirement was set to go into effect on June 1. However, copays will still be required. As the system noted in a statement, 'in 2024, more than half of copays were not paid when Cleveland Clinic provided services.' Previously, patients were billed for unpaid copays, and interest-free payment plans were not available specifically for copays. Bradley Herring, PhD, a professor who studies health policy at the University of New Hampshire, Durham, New Hampshire, told Medscape Medical News that Cleveland Clinic likely buckled in response to public backlash over the pay-or-else copay mandate. 'It's just not a good look, especially for nonprofit providers,' he said. But copays, Herring said, do have a purpose: To discourage patients from seeking healthcare they don't need. 'The goal is to try and cut down on some overuse of healthcare utilization,' he said. 'If you can increase some cost sharing and have the patient pay something, that might cut down on some of those patients who don't really benefit from it a lot.' How the Copay Policy Was Supposed to Work? The Cleveland Clinic runs 23 hospitals and serves 3.5 million patients, mostly in Ohio. Earlier this year, it announced that it would require copays before or at check-in for outpatient appointments such as scheduled office visits, services such as physical and occupational therapy, outpatient diagnostic testing, and outpatient procedural visits. Emergency services, surgeries, inpatient hospital stays, cancer treatments were slated to be exempt. Urgent/express visits were to be excluded too 'at this time.' The new policy wouldn't have applied to Medicaid or traditional Medicare patients. 'If you can't make your copay,' the health system said, 'we'll help you reschedule your visit.' Critics put the clinic on blast at a City Council meeting in May. According to Councilman Richard Starr declared the policy is 'slap in the face' to local citizens. 'People are going to be scared to trust the hospitals because it's always about the dollar and not about the healthcare that is needed, and needs to be provided, for those individuals,' Starr said. A 69-year-old man told WKYC-TV that his monthly copays would cost nearly $500. 'In my opinion, it's making the Cleveland Clinic look like patient care is secondary and finances are first,' he said. 'I'm not happy with it, not one bit.' However, a health system representative 'told City Council that with $70 million in unpaid copays in 2024 and a slim 1.7% operating margin, the Clinic must collect more revenue to maintain services and invest in community programs,' reported. Why Do Copays Exist in the First Place? Cleveland Clinic's revised policy will still require copays to be paid by 'the time of service,' Cleveland Clinic Spokeswoman Angela Smith told Medscape Medical News. Will patients be refused care if they decline to pay even if they are offered a 0% interest payment plan? Smith didn't answer this question directly but said 'patients who do not have the means to pay for services provided at our facilities may request financial assistance.' Alison Evans Cuellar, PhD, MBA, professor of Health Administration and Policy at College of Public Health, George Mason University, in Fairfax, Virginia, told Medscape Medical News that copays translate to higher prices for consumers and lower demand overall. The Affordable Care Act eliminated some cost sharing precisely because of evidence that patients forgo valuable care when faced with copays or deductibles, she said. 'Not all care is high value and we want to avoid overuse but not for important preventive services, insulin, and so forth.' 80% of Something or 100% of Nothing Herring pointed out that copays are imposed by insurers, but providers collect and keep them. 'Margins are getting tighter,' he said, 'and you can understand the financial incentive to do something to try and increase that collection rate.' Providers could waive copays. But an online post by Jackson LLP, a healthcare attorney firm with offices around the country, noted that this can be legally dicey, especially if patients don't have proven financial hardship. For one thing, 'routinely or regularly waiving copays for Medicare or Medicaid patients poses several potential problems for your practice,' the post said. 'Because both Medicare and Medicaid are federally funded programs, you risk violating multiple federal laws.' Waiving private insurance copays can put providers in legal jeopardy too, the post said. On the other hand, there's a financial downside to cancelling an appointment because a patient doesn't cough up a copay, he said. 'To not provide the service right then and there, when you've got the provider ready to provide it, seems really wasteful.' If the copay is 20%, he said, 'isn't 80% of something better than 100% of nothing?'