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Innovations in tech and health dominate Quantum India Summit in Bengaluru

Innovations in tech and health dominate Quantum India Summit in Bengaluru

Deccan Herald2 days ago
Following a keynote lecture by 2004 Nobel Laureate David Gross, a panel discussion on the topic 'Creating a coherent ecosystem of startups for quantum technologies in India' was organised.
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What Is The Doomsday Clock And Why ‘Midnight' Is Considered The Point Of No Return
What Is The Doomsday Clock And Why ‘Midnight' Is Considered The Point Of No Return

News18

time3 hours ago

  • News18

What Is The Doomsday Clock And Why ‘Midnight' Is Considered The Point Of No Return

Every year, it reminds us how close we are to catastrophe. From nuclear war to climate change, here's why the Doomsday Clock now stands at just 89 seconds to midnight In the University of Chicago's Keller Centre, a simple clock sits frozen at 89 seconds to midnight. There is no ticking sound. No countdown timer. And yet, each January, this symbolic clock captures global attention, from newsrooms and nuclear war rooms to climate science labs and policy circles. This is the Doomsday Clock, not a scientific instrument, but a warning sign, crafted by atomic scientists and artists in the aftermath of World War II. It marks not the passage of time, but how little time humanity may have left before it self-destructs. Updated just once a year, the clock's minute hand has become a powerful barometer of global crisis. And in January 2025, it moved again. Just 89 seconds to midnight. The closest we've ever been to metaphorical annihilation. So what exactly is the Doomsday Clock? Who decides where its hands go? And what will happen if the clock strikes midnight? What Is The Doomsday Clock? The Doomsday Clock is a metaphorical timepiece symbolising humanity's proximity to global catastrophe, such as nuclear war or climate collapse. Created in 1947 by scientists from the Manhattan Project, the clock is updated each year by the Bulletin of the Atomic Scientists to warn the public of growing existential threats, both man-made and preventable. The 'time" on the clock reflects a judgement, not a prediction: the closer to midnight, the greater the danger. This year, the Bulletin moved the hands to 89 seconds to midnight, the closest humanity has ever been to symbolic self-destruction. Where Did The Clock Come From? The Doomsday Clock was originally conceived by Martyl Langsdorf, an abstract landscape artist married to Manhattan Project physicist Alexander Langsdorf Jr. In 1947, she was asked to design a cover for the Bulletin's first issue as a magazine. Moved by the urgency she sensed from scientists debating nuclear risk, she sketched a minimalist clock with hands set at seven minutes to midnight, purely for visual impact. Behind the symbolism lay deep regret. Many Manhattan Project scientists, including Leo Szilard and James Franck, had warned against using the atomic bomb on civilians. After the Hiroshima bombing, Szilard called it 'one of the greatest blunders in history." Within weeks, these scientists created the Bulletin of the Atomic Scientists to raise public awareness of the dangers posed by nuclear weapons. How Is The Doomsday Clock Set? Initially, the Bulletin's founding editor Eugene Rabinowitch, a scientist and arms control advocate, alone decided the clock's time. After his death in 1973, the responsibility passed to the Science and Security Board—a group of 18 experts in nuclear policy, climate science, international security, and emerging technologies. Today, the board meets twice a year, consulting widely with global experts and Nobel laureates. In addition to scientific data, they consider: They do not forecast the future but make evidence-based assessments of current threats and societal responses. Why Was It Moved To 89 Seconds This Year? On January 28, 2025, the Bulletin reset the clock to 89 seconds to midnight, its closest-ever position, citing: 'The world has not made sufficient progress on existential risks threatening all of humanity," said Daniel Holz, chair of the Science and Security Board. 'When you are at this precipice, the one thing you don't want to do is take a step forward." A Brief History: How Often Has The Clock Moved? Since 1947, the Doomsday Clock has been adjusted 26 times. Some of the most notable moments include: 1949: After the Soviet Union's first nuclear test, the clock was moved from 7 to 3 minutes to midnight. 1991: At the end of the Cold War, after the Strategic Arms Reduction Treaty (START), it moved to 17 minutes to midnight, the farthest ever. 2007: For the first time, climate change was formally included in hand-setting discussions. 2018: Citing nuclear uncertainty and international breakdowns, it was reset to 2 minutes. 2020–2025: A steady worsening of global trends brought the time from 100 seconds to 89 seconds, year by year. Notably, the clock was not moved during the Cuban Missile Crisis of 1962, as too little was known publicly about the standoff at the time. What Happens If the Clock Strikes Midnight? Midnight represents global catastrophe—not a literal event, but a metaphor for nuclear war, irreversible climate collapse, or technological meltdown. It is intended to shock, not predict. Originally tied to atomic warfare, the metaphor has since expanded. As Rachel Bronson, president and CEO of the Bulletin of the Atomic Scientists, explained in an interview with the University of Chicago's Big Brains podcast: 'There are tipping points in climate that you can't come back from… the clock is a warning that we may not feel the consequences until it's too late." Why Do Some People Dismiss It? While the Doomsday Clock garners international headlines, critics question its scientific basis. Some argue that the clock is too symbolic and subjective, lacking scientific rigour or a clearly defined methodology. They point out that it does not quantify risk in measurable terms and has no predictive accuracy. Others see it as Western-centric, shaped largely by American and European perspectives on global threats. There's also criticism that the clock's once-a-year adjustment feels out of sync with rapidly evolving global crises, and that its dramatic framing may provoke alarm rather than action. How The Doomsday Clock Entered Pop Culture Over the decades, the Clock has become more than a scientific symbol; it has become a pop culture icon. In the acclaimed Watchmen comics and their film and TV adaptations, the ticking clock becomes a literal countdown to nuclear war, mirroring Cold War anxieties. British heavy metal band Iron Maiden's 1984 hit '2 Minutes to Midnight" directly references the Clock, critiquing the arms race and political brinkmanship. Even in the X-Men universe, especially in stories like Days of Future Past, time is a recurring symbol of extinction-level threats, echoing the same existential urgency. Its visual simplicity makes it an enduring metaphor across art, cinema, literature, and political commentary. top videos View all Why The Clock Still Matters In an age of disinformation and short attention spans, the Doomsday Clock endures because it translates complex global threats into a simple, universal image. When the Bulletin moves the hands, the world takes notice, not because the clock is infallible, but because the danger is real. About the Author Karishma Jain Karishma Jain, Chief Sub Editor at writes and edits opinion pieces on a variety of subjects, including Indian politics and policy, culture and the arts, technology and social change. Follow her @ More Get Latest Updates on Movies, Breaking News On India, World, Live Cricket Scores, And Stock Market Updates. Also Download the News18 App to stay updated! tags : Apocalypse climate change Doomsday Clock nuclear war view comments Location : New Delhi, India, India First Published: August 03, 2025, 08:00 IST News explainers What Is The Doomsday Clock And Why 'Midnight' Is Considered The Point Of No Return Disclaimer: Comments reflect users' views, not News18's. Please keep discussions respectful and constructive. Abusive, defamatory, or illegal comments will be removed. News18 may disable any comment at its discretion. By posting, you agree to our Terms of Use and Privacy Policy.

Machines may soon think in a language we don't understand, leaving humanity in the dark: Godfather of AI sounds alarm
Machines may soon think in a language we don't understand, leaving humanity in the dark: Godfather of AI sounds alarm

Economic Times

time16 hours ago

  • Economic Times

Machines may soon think in a language we don't understand, leaving humanity in the dark: Godfather of AI sounds alarm

Synopsis Artificial Intelligence pioneer Geoffrey Hinton cautions about AI's future. Hinton suggests AI could create its own language. This language might be beyond human understanding. He expresses regret for not recognizing the dangers sooner. Hinton highlights AI's rapid learning and knowledge sharing capabilities. He urges for ethical guidelines alongside AI advancements. The goal is to ensure AI remains benevolent. Agencies Geoffrey Hinton, the "Godfather of AI," warns that AI could develop its own incomprehensible language, potentially thinking in ways beyond human understanding. Hinton, a Nobel laureate, regrets not recognizing the dangers of AI sooner, emphasizing the rapid pace at which machines are learning and sharing information. Geoffrey Hinton, often dubbed the 'Godfather of AI,' has once again sounded a sobering alarm about the direction in which artificial intelligence is evolving. In a recent appearance on the One Decision podcast, Hinton warned that AI may soon develop a language of its own — one that even its human creators won't understand. 'Right now, AI systems do what's called 'chain of thought' reasoning in English, so we can follow what it's doing,' Hinton explained. 'But it gets more scary if they develop their own internal languages for talking to each other.' He went on to add that AI has already demonstrated it can think 'terrible' thoughts, and it's not unthinkable that machines could eventually think in ways humans can't track or interpret. Hinton's warnings carry weight. The 2024 Nobel Prize laureate in Physics, awarded for his pioneering work on neural networks, has helped lay the foundation for today's most advanced AI systems, including deep learning and large language models. But today, Hinton is wrestling with what he calls a delayed realization. 'I should have realised much sooner what the eventual dangers were going to be,' he said. 'I always thought the future was far off and I wish I had thought about safety sooner.' That hindsight is now driving his advocacy. Hinton believes that as digital systems become more advanced, the gap between machine intelligence and human understanding will widen at a staggering pace. One of Hinton's most compelling concerns is how digital systems differ fundamentally from the human brain. AI models, he says, can share what they learn instantly across thousands of copies. 'Imagine if 10,000 people learned something and all of them knew it instantly — that's what happens in these systems,' he explained on BBC News . It's this kind of distributed, collective intelligence that could soon allow machines to outpace even our most ambitious understanding. AI models like GPT-4 already surpass humans in general knowledge, and though they lag in complex reasoning for now, Hinton says that gap is closing fast. While Hinton has made waves by speaking openly about AI risks, he says others in the tech world are staying quiet — at least in public. 'Many people in big companies are downplaying the risk,' he noted, despite their private concerns. One exception, he says, is Google DeepMind CEO Demis Hassabis, who has shown serious commitment to addressing those risks. Hinton's own exit from Google in 2023 was widely misinterpreted as a protest. He now clarifies, 'I left Google because I was 75 and couldn't program effectively anymore. But when I left, maybe I could talk about all these risks more freely.' With AI's capabilities expanding and governments scrambling to catch up, the global conversation around regulation is intensifying. The White House recently unveiled an 'AI Action Plan' aimed at accelerating innovation while limiting funding to overly regulated states. But for Hinton, technical advancements must go hand in hand with ethical guardrails. He says the only real hope lies in finding a way to make AI 'guaranteed benevolent' — a lofty goal, given that the very systems we build may soon be operating beyond our comprehension.

Scientists use AI-designed proteins to generate immune cells
Scientists use AI-designed proteins to generate immune cells

The Hindu

timea day ago

  • The Hindu

Scientists use AI-designed proteins to generate immune cells

A team of Harvard scientists has used artificial intelligence (AI), in the form of AI-designed proteins, to generate large numbers of immune cells and enhance immunity against diseases ranging from cancer to viral infections, a new research paper published in Cell said. The scientists engineered a synthetic activator of a key cellular pathway called Notch signalling, which plays a crucial role in cellular differentiation and is essential for transforming human immune progenitors into T cells. Notch signalling is a cell-to-cell communication system vital for various developmental processes and tissue homeostasis in multicellular organisms. Homeostasis is the body's way of keeping everything balanced and stable, despite what is happening around it. 'In response to viral infections or cancer, the body requires a higher production of T cells to mount an effective immune defence. However, this process depends on the activation of the Notch signalling pathway, for which no effective molecular activators have been available,' Rubul Mout from Assam, the principal scientist of the study, said. Associated with the Harvard Stem Cell Institute and the Stem Cell & Regenerative Biology Program at Boston Children's Hospital, he is one of 24 scientists involved in the collaborative effort. They include George Daley, the Dean of Harvard Medical School, and Nobel laureate David Baker. Improved method According to the study, an earlier method of activating Notch signalling in laboratory settings by immobilising Notch ligands on tissue culture dishes is not applicable for therapeutic use in humans. The quest for a viable, soluble activator of Notch signalling that could work in vivo (inside a living body) made the team develop a library of custom-designed soluble Notch agonists and systematically test their ability to activate the Notch pathway and support T cell development and function. AI-driven protein design technologies, an innovation that contributed to Dr Baker receiving the 2024 Nobel Prize in Chemistry along with Demis Hassabis and John Jumper, were used to address the challenge. Using the agonists, the researchers demonstrated the large-scale generation of T cells in a laboratory bioreactor, an important advancement given the growing demand for T cell production in hospitals worldwide for Chimeric Antigen Receptor (CAR) T cell-based cancer immunotherapies. Furthermore, when the agonists were injected into mice during vaccination, the animals displayed significantly improved T cell responses, indicating an enhanced immune response. The treatment resulted in increased production of memory T cells, which are crucial for the long-term impact of vaccines. 'Being able to activate Notch signalling opens up tremendous opportunities in immunotherapy, vaccine development, and immune cell regeneration,' Dr Mout said. 'What excites me the most is using this technology to engineer synthetic proteins that simultaneously bridge T cells and cancer cells, boost T cell-mediated killing, and neutralise the immunosuppressive tumour micro-environment. Our goal is to develop next-generation immunotherapies and cancer vaccines,' he added. The other collaborators of the study include Urban Lendahl of the Stockholm-based Karolinska Institutet and a former Chairman of the Physiology and Medicine Nobel Committee, Stephen C. Blacklow, the Chair of Harvard Medical School's Department of Biological Chemistry and Molecular Pharmacology, and R. Grant Rowe of Boston's Dana-Farber Cancer Institute.

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