
Huge cuts to mRNA research spark fears about future pandemics
'I've tried to be objective & non-alarmist in response to current HHS actions—but quite frankly this move is going to cost lives,' President Trump's former surgeon general Jerome Adams said in a post to X.
'mRNA technology has uses that go far beyond vaccines… and the vaccine they helped develop in record time is credited with saving millions.'
The first COVID-19 mRNA vaccines from Pfizer and Moderna hit the market in 2021, just a year after the virus first appeared. Vaccines typically take years to develop, but the mRNA shots were developed in record time due to a massive influx of funding from the first Trump administration, dubbed Operation Warp Speed.
The COVID shots proved safe and effective, and helped bring about an end to the pandemic. Experts say mRNA technology has the potential to revolutionize treatments for evolving pathogens, especially bird flu, because the platform can be easily modified.
On Tuesday, Kennedy cancelled $500 million worth of contracts related to mRNA vaccine research being funded by the Biomedical Advanced Research and Development Authority.
Instead, he said the agency will focus on platforms with 'stronger safety records.'
Public health experts point out that reviews of the hundreds of millions, if not billions, of doses of mRNA shots administered worldwide have found very few adverse events.
'It's pretty clear that the administration, or at least the secretary, has a political vendetta not just against vaccines but against mRNA in general,' said Jeff Coller, a professor of RNA biology and therapeutics at Johns Hopkins University.
Coller said the move will put the U.S. behind other nations in biomedical research and sends a 'clear message' to scientists and the industry that it is not wise to invest in mRNA technology because if they do, they will likely not receive funding or approval from the federal government.
Jennifer Nuzzo, a professor of epidemiology and director of the Pandemic Center at Brown University School of Public Health, told The Hill that the cancellation is a threat to national security, as it opens the U.S. to future public health emergencies caused by biological warfare.
'One of the ways that we deter that from happening is to say the United States is absolutely committed to preparedness,' Nuzzo said. 'When we take them off the table and leave nothing in their place, we basically signal to our adversaries that we are no longer interested in defending ourselves.'
In the long run, Nuzzo said, winding down research efforts on mRNA vaccine platforms will stifle medical innovation coming out of the U.S., including new treatments for diseases like cancer.
'It's troubling on a number of fronts,' she said.
MRNA vaccines work by sending instructions to cells to make a specific type of protein found on the outer membrane of a virus. The body's immune system is then able to recognize that protein as something foreign and will create antibodies to fight it.
That same general approach could be used to help potentially vaccinate someone against a particular cancer, according to Nuzzo.
'Cancers have a genetic signature,' she said. 'We don't know what's going to happen but there are some preliminary studies that suggest it could be a very promising way to treat cancers.'
None of the canceled contracts directly deal with cancer research, but the move will likely cause a chilling effect among researchers that ultimately impacts cancer-related work, said Michael Osterholm, founding director of the Center for Infectious Disease Research and Policy and member of the Vaccine Integrity Project.
'I think you're going to see anyone who is willing to invest in mRNA technology, pulling back, if not completely, getting out of this business,' he said.
'This is terribly unfortunate, given that we have a number of other infectious diseases for which this vaccine platform was being explored in terms of taking on other infectious diseases and including some cancer vaccines.'
Kennedy is deeply skeptical of vaccines in general, and mRNA vaccines in particular.
In 2021, he falsely said the mRNA COVID-19 vaccine was the 'deadliest vaccine ever made.' Kennedy has also been facing pressure from fellow anti-vaccine activists for not doing enough to keep mRNA vaccines off the market.
He was criticized earlier this year when the Food and Drug Administration approved Moderna's updated COVID-19 vaccine, even though the agency limited its use in children.
In a video posted to X on Tuesday, Kennedy falsely claimed mRNA shots don't protect against respiratory viruses and don't work if a virus mutates.
'One mutation and the vaccine becomes ineffective,' Kennedy said.
Following the announcement, public health experts urged Congress to restore funding towards mRNA vaccine research, with some calling it an 'assault' on federal vaccine policy.
'The HHS Secretary continues a mindless assault on sound federal vaccine policy,' said Robert Steinbrook, director of the Public Citizen Health Reseach Group.
'The mRNA vaccine platform was essential to rapid vaccine development and deployment during the COVIVD-19 pandemic and remains essential to preparing for future public health emergencies.'
But the full extent of Kennedy's move isn't known.
A Moderna spokesperson told The Hill that they were not aware of any new award cancellations since their contract to help develop an H5N1 bird flu vaccine was canceled in May.
Gritstone Bio, another company on the HHS list of cancelled contracts, ceased operations earlier this year after the company filed for bankruptcy in 2024.
A spokesperson for Tiba Bio said HHS's decision to terminate their BARDA contract 'comes as a surprise' since its contract was for a therapeutic, not a vaccine, and it does not use mRNA technology. Instead, it uses a method called RNA interference, which the FDA approved to treat some diseases in 2018.

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Yahoo
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Signing up for an intense, early-morning boot camp or challenging yourself to use your monthly gym pass every day might not be sustainable over time. Personal trainer Kristen McParland says that it's 'really difficult for a beginner to go from zero days to five.' It's better to 'smart small and build,' she advises. Maybe that's hitting an exercise class twice a week to start, or going for a run on Sunday mornings until you get into a nice groove. And don't push yourself to work out in the mornings if you loathe getting up early — you'll eventually abandon your routine. As McParland says, the 'best time' to work out is the one that works for you and your body. 🍪 Cut back on ultraprocessed foods Need one more reason to cut out ultraprocessed foods, such as packaged cookies and chips? A new study published in Thorax found that eating them could up your risk of lung cancer, Prevention reports. While it's unclear what is behind this association, it's not the first study to find negative impacts of ultraprocessed foods, which can often be higher in sugar and fat, as well as lower in fiber, vitamins and minerals, than whole food options. One way to combat the health risks of ultraprocessed foods is to aim for whole foods (vegetables, fruit, meat, fish, nuts and eggs) whenever possible. 🐟 Eat fatty fish for better cholesterol When we think of cholesterol, we often think about reducing our 'bad cholesterol' — aka LDL, which can build up in the arteries and increase the risk of heart disease. But you also need to think about your 'good cholesterol,' called HDL, which helps remove excess cholesterol from the bloodstream. One way to do that, our friends at EatingWell say, is to add more fatty fish, like salmon, mackerel and sardines. to your diet. They're rich in omega-3s, which have been shown to boost HDL and reduce inflammation in the body. Keep things simple by going with the tinned fish variety, which you can add to a salad or eat alone with a cracker. 😋 Go for cumin Time to spice things up. Adding cumin to your meals could come with gut health benefits, the Independent reports. The warm, nutty spice is rich in antioxidants, and past research has found that it can help alleviate symptoms of irritable bowel symptom, such as uncomfortable bloating. If you want the most out of cumin, make sure to grind it up: it'll help your body absorb some of its other nutritional perks, such as B vitamins, vitamin E, iron and magnesium. 🍵 Drink tea Break out the kettle. Drinking certain teas can help you manage your blood pressure, cardiologist Dr. Ragavendra Baliga tells Prevention. Why? These teas — particularly green and hibiscus — contain blood vessel-widening polyphenols, which allows for better blood flow and oxygen delivery to the rest of your body. 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Boston Globe
an hour ago
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