Oxford study reveals the shocking truth about life after weight-loss injections. Is the jab really worth it?
Weight-loss injections help shed kilos fast—but what happens after? An Oxford study finds people typically gain all the weight back within 10 months of stopping. With growing popularity and celebrity endorsements, the findings expose a critical gap: without long-term support, the results don't last.
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Experts caution that unless paired with behavioural and lifestyle support, the effects of the weight-loss jabs may be temporary
Weight Loss or Lifelong Management?
For thousands chasing rapid weight loss , injectable drugs have become the magic key—suppressing appetite, shedding kilos, and delivering fast results. But new research from the University of Oxford warns that the fairy tale might come with an unwelcome twist: the weight, once lost, may boomerang back far sooner than imagined.Presented at the European Congress on Obesity, the Oxford study reviewed 11 different clinical trials involving over 6,000 adults. It found that users of weight-loss jabs—whether older-generation or the newer, high-dose ones—typically saw an average drop of 8 kilograms. However, within just 10 months of stopping the injections, most returned to their original weight. For those on newer, more potent drugs, the trajectory was no different—only steeper.According to a report from The Guardian, patients on the latest high-dose medications lost as much as 16 kilograms. But within a year, they regained over 9 kilograms, suggesting a full weight rebound was likely in just under two years. These aren't isolated cases either—the numbers come from large-scale randomized controlled trials and observational studies, marking a serious red flag for healthcare systems and private users alike.The findings challenge a widespread perception: that a jab can solve weight issues permanently. Instead, experts caution that unless paired with behavioural and lifestyle support, the effects of the drug may be temporary. Professor Susan Jebb, one of the study's authors, noted that unlike diets, which require sustained willpower, these drugs suppress hunger biologically. So, when the medication stops, so does the effect—without any lasting behavioural change to fall back on.'What we're seeing is that while these drugs are very effective at helping people lose weight, the regain after discontinuation is significantly faster than what we observe after diets,' said Jebb. Her warning poses a tough question for policymakers: should health services invest in expensive weight-loss injections if patients are likely to regain all the weight once treatment ends?The deeper issue lies in how society views weight loss itself. Is it a one-time event, or a continuous process? If weight-loss jabs are to be effective, experts say, they must be part of a longer-term strategy involving sustained behavioural change, not a standalone shortcut.Jason Halford from the European Association for the Study of Obesity echoed this concern, emphasizing that these medications are 'an adjunct to behavioural change—not a replacement.'As the popularity of injectable weight-loss treatments soars, the Oxford study brings timely and sobering insight: the end of the jab is not the end of the journey. For lasting results, the real work may begin the day the needle stops.
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