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Goodbye to Melatonin and Hello to Magnesium. Here's Why You Should Use This Supplement for Sleep

Goodbye to Melatonin and Hello to Magnesium. Here's Why You Should Use This Supplement for Sleep

CNETa day ago

Melatonin is undoubtedly the most popular go-to sleep supplement on the market. However, melatonin isn't best for everyone. In fact, it can give some people bizarre dreams or leave them feeling groggy the next day.
If you're one of those people, there's an alternative to melatonin. Another sleep aid that's gained recent popularity is magnesium, which is said to calm your nervous system and help you get quality sleep.
Read on to learn about magnesium's benefits, types and dose suggestions. Magnesium might just be the powerful sleep aid that you've been searching for.
What is magnesium?
Magnesium is an essential mineral in the body that plays a key role in regulating blood pressure, protein synthesis, muscle and nerve function and blood sugar. Magnesium also helps in bone development, energy production, improving sleep and maintaining a normal heart rhythm.
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Magnesium is present in several foods, such as:
Green leafy vegetables
Legumes
Nuts
Seeds
Soy products
Whole grains
If your diet lacks such foods, you may require magnesium supplementation. Several magnesium supplements are available that provide various health benefits. You must talk with your doctor before taking magnesium supplements for your sleep.
Benefits of magnesium for sleep
Magnesium supplementation can help you get better and longer sleep, resulting in less tiredness during the day. Magnesium also can treat sleep disorders such as insomnia and restless leg syndrome, helping you fall asleep easily and improving your sleep quality.
Decreases insomnia
Insomnia is a condition characterized by difficulty falling asleep, staying asleep or early waking. It affects about 10% to 48% of the global population, with the percentage being higher for the elderly. Magnesium plays a role in the production of melatonin, a hormone associated with the normal sleep-wake cycle of the body. Studies suggest that magnesium deficiency can decrease melatonin concentration, thereby interfering with sleep.
Magnesium can also be combined with other supplements, such as melatonin and vitamin B complex, to reduce insomnia symptoms and improve sleep quality.
Can treat restless leg syndrome
Restless leg syndrome is a neurological condition that causes uncomfortable sensations such as tingling, creeping or crawling in your legs and an irresistible urge to move them. RLS can disrupt your sleep, making it difficult to fall asleep as people are forced to move their legs to relieve the sensations. Research suggests magnesium supplementation can help relax your muscles, which can relieve your discomfort and make you fall asleep easily.
Calms the central nervous system
Magnesium can regulate sleep by activating gamma-aminobutyric acid, a chemical messenger that reduces the excitement or firing of neurotransmitters and calms the nervous system. Magnesium can also inhibit the N-methyl-d-aspartate receptor which promotes muscle relaxation. Studies have also suggested that magnesium supplementation can reduce the concentration of a stress hormone, serum cortisol, which further calms the nervous system and promotes better sleep.
May relieve anxiety and depression
Anxiety and depression can increase the risk of insomnia. Research suggests that magnesium may diminish anxiety and mild to moderate depression, which may also help to improve sleep quality. Speak with your doctor about any concerns you may have about your mental health.
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What type of magnesium is best for sleep?
Several types of magnesium supplements are available, each having their own health benefits. The following are a few that can help you get a good night's sleep:
Magnesium glycinate: This form of magnesium can be easily absorbed by your body, promoting relaxation and better sleep. Being easily absorbed also means it is unlikely to cause serious side effects. Magnesium glycinate can also treat depression, which may cause sleep problems.
This form of magnesium can be easily absorbed by your body, promoting relaxation and better sleep. Being easily absorbed also means it is unlikely to cause serious side effects. Magnesium glycinate can also treat depression, which may cause sleep problems. Magnesium L-threonate: Magnesium L-threonate is a safe and bioavailable form of magnesium that can help to improve sleep quality, mood fluctuations and daytime activities.
Magnesium L-threonate is a safe and bioavailable form of magnesium that can help to improve sleep quality, mood fluctuations and daytime activities. Magnesium oxide: This form is less bioavailable than the other two. Research suggests that magnesium oxide can help to improve insomnia symptoms in older adults.
Magnesium dose for sleep
The amount of magnesium a person can take daily depends on their age and any existing health conditions. The recommended daily intake ranges from 400mg to 420 mg for adult men and 310mg to 320 mg for adult women, per the Food and Nutrition Board at the Institute of Medicine of the National Academies.
This recommended amount is a general guideline for overall magnesium intake but not specifically for sleep. Talk to your doctor or a sleep expert before taking magnesium supplements for sleep. They can recommend the supplement most suitable for you since some forms of magnesium can interfere with certain prescription drugs.
Bottom line
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Magnesium supplements have recently gained popularity as a sleep aid. They can help calm your nervous system, relax muscles, improve depression and anxiety symptoms and may even treat conditions such as restless leg syndrome and insomnia. Consult with your doctor before taking any magnesium supplements for sleep. Some vitamins and supplements may interfere with other medications and cause side effects such as abdominal cramps, diarrhea or nausea. Your doctor can recommend the type and dose of magnesium most suitable for you.

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The Next-Gen Sweetener You May Be Eating
The Next-Gen Sweetener You May Be Eating

WebMD

time18 minutes ago

  • WebMD

The Next-Gen Sweetener You May Be Eating

June 6, 2025 – It's time to add the word "neotame" to your ingredient label watch list, especially if you vape. It's a relatively new artificial sweetener found in every disposable e-cigarette that researchers tested – and the ultra-sweet substance is increasingly being used in food and drink. You probably have heard of aspartame. But neotame is its lesser-known sibling, with just one molecular difference. It showed up in laboratory tests of 11 top disposable e-cigarette brands when researchers from Duke and Yale Universities were trying to figure out what makes the vapes, like Elf and Geek Bars, so, so sweet. Neotame is between 7,000 and 13,000 times sweeter than table sugar and up to 65 times sweeter than aspartame. The sweetened e-cig study results were published this week in The Journal of the American Medical Association, or JAMA. Neotame wasn't found in JUUL or other cartridge-based devices, which have their own checkered ingredient history, including the 2019 finding that the sucralose used in them was linked to the production of toxic aerosols. Even if you don't vape, you may already be consuming neotame, since it's found in baked goods, candy (Mentos, for example), and gum – plus salad dressing, fruit spreads, dairy desserts, and yogurt. It's also used in some flavored sparkling waters and drinks like Tampico Mango Punch. Some researchers have soured on neotame because its use makes e-cigs appealing to young people, and because lab tests show it may harm our intestines when ingested. Why You've Never Heard of Neotame Maybe you saw it on an ingredient label and passed over it sometime in the past two decades. It has zero calories, no nutritional value, and was FDA-approved as a food additive in 2002. It's not listed on disposable e-cigarette packaging. Researchers track these sweeteners. Havovi Chichger, PhD, a professor at Anglia Ruskin University in Cambridge, England, says that for more than four decades, we have been consuming "traditional" artificial sweeteners like acesulfame potassium (Ace-K), sucralose, saccharin, and aspartame. But newer substances like neotame "herald the next generation of sweet additives," she said. The substance was developed in the 1990s in a quest for a more stable sweetener for processed products, and its use has steadily grown, she said. It's even used now in some lip cosmetics that have a sweet flavor and aroma. Neotame has also become the 21st-century spoonful of sugar Mary Poppins sang about: It's used to make some pharmaceuticals more palatable. According to a website about neotame set up by Georgia-based maker NutraSweet Co., neotame has an "ability to mask the taste of supplements, vitamins, bitter food ingredients and active pharmaceuticals. Moreover, its high sweetness intensity allows formulation at very small quantities, leaving ample room for your pharmaceutical ingredients." Neotame is not, however, approved for use in products that are inhaled. Why Neotame Is Used in E-Cigarettes – and in Baked Goods The liquid vaporized by e-cigarettes is heated sometimes as hot as 800 degrees Fahrenheit, said Sven Jordt, PhD, senior author of the JAMA study and a Duke University professor who is an expert in chemical sensory biology. Heating vape liquid can chemically change its ingredients, and neotame's strong sweetness and heat stability seem to have led to its new use in vapes, he said. If a lot of a sweetener is burned up or chemically changed when heated, the desired taste profile can still be achieved if just a bit of the ultra-sweetness remains. "The FDA also has determined that neotame can be used for baking, for example, because it's more heat stable than many of the other sweeteners," Jordt said. "Sweeteners like aspartame or Ace K, they are basically burned at normal baking temperatures. However, with neotame, a large proportion survives baking and likely also survives being vaporized by e-cigarettes." His team is concerned that the sweetness makes the products particularly attractive to kids. It's not used in the few e-cigarettes that are legal to sell in the U.S. and was just found in the disposable ones that are illegal but widely available amid lack of enforcement. "We did this study specifically because this category of disposable e-cigarettes is seeing an explosive growth in sales and use," Jordt said, noting that their nicotine concentration is higher than in older products, and at a fraction of the price. "You buy this once and then you can use it a whole week. And kids are puffing on these all the time," he said. "Some have like 15,000 or 20,000 puffs [compared to a few hundred puffs in the older JUUL devices]. So if you use this continuously, you become really heavily addicted to nicotine … and now we are asking: Is it just the design or is there something else in it that makes them much more attractive to kids to use and make them taste better? And then we found this neotame." The Damage Neotame Can Cause Approval of neotame for use in food products was based on studies on mice and other animals that didn't show any adverse physical effects. But what about the effects on humans? Findings published last year suggest that neotame can damage the human intestine. "Neotame can cause previously healthy gut bacteria to become diseased and invade the gut wall – potentially leading to health issues including irritable bowel syndrome and sepsis – and also cause a breakdown of the epithelial barrier, which forms part of the gut wall," said Chichger, who is a cell and molecular biologist and senior author of the study, which was published in the journal Frontiers in Nutrition. The study showed that neotame can damage the "intestinal epithelium," or lining, by causing the death of epithelial cells. It also damages bacteria commonly found in the gut, she added. "Despite the smaller quantities used, the impact of neotame on the epithelium-microbiota relationship has the potential to cause poor gut health, which in turn could lead to metabolic and inflammatory diseases." The findings were the latest in a line of studies showing the effects of artificial sweeteners on gut health. Another recent study led by Los Angeles-based endocrinologist Ruchi Mathur, MD, linked artificial sweeteners to changes in the microbial composition and diversity in stool and the small intestine. That research, which was published in the journal Cell, didn't include neotame. Changes observed in the gut microbiome's biochemical activity "raise concerns regarding the potential impacts of non-sugar sweeteners on metabolic and gastrointestinal health," said Mathur, who is director of the Diabetes Outpatient Teaching Education Center and a professor of medicine at Cedars-Sinai in California. All the experts interviewed for this article said that while there's not enough data to say for sure that inhaling neotame is bad for you, the existing research suggests reasons to be cautious. When you vape, some of the "smoke" can mix with saliva and get swallowed – so neotame could reach your gut, Chichger said. "In fact, there are other studies which show that e-cigarette fluid can cause the same level of damage that we noted from neotame." Unanswered Questions About Neotame Big questions about neotame: How does it affect the lungs? How can we keep track of how much we've consumed (eating, drinking, or inhaling)? And how much is too much? "These sweeteners are only approved for use in food, but not for inhalation," Jordt said. "We don't know how safe they are if you inhale them every day." Mathur noted that the lungs have their own microbiome, and past studies have shown that vaping alters saliva as well as the nasal cavity microbiome. A large study published in March showed a significant link between exclusive e-cigarette use and development of COPD. The FDA has set daily intake limits for neotame, which is sometimes referred to by the brand name Newtame, and other sweeteners. But experts say there is no labeling requirement that shows consumers how much is included in a product, whether it's food, drink, or vape liquid. Jordt said it's unlikely someone would reach that limit by vaping alone. But if you also eat products with the sweetener, then exceeding that limit becomes more likely. "I do think it is reasonable to assume that there should be consumer awareness and caution, as there is little if any data on what happens when this substance is inhaled," Mathur said. You should also be aware of artificial sweeteners in food and drink, Mathur said. Make a plan with your doctor, especially if eating artificially sweetened foods is part of how you manage your body weight or diabetes. "There is enough data to suggest it is safe to use these non-sugar sweeteners in moderation," Mathur said. "If someone uses artificial sweeteners in non-traditional ways, such as inhaling it through an e-cigarette, they are doing so without the benefit of any good information on the potential long-term consequences of taking in the substance through their airways and down into their lungs or what byproducts may be created in the process."

Dr. Arthur Zacco Celebrates Three Decades of Excellence in Hair Restoration
Dr. Arthur Zacco Celebrates Three Decades of Excellence in Hair Restoration

Associated Press

timean hour ago

  • Associated Press

Dr. Arthur Zacco Celebrates Three Decades of Excellence in Hair Restoration

Dr. Zacco's AZ Hair Restoration clinic utilizes advanced techniques like FUT, FUE, and MFU grafting to deliver seamless, natural-looking hair restoration. His patient-focused approach combines precision, artistry, and compassionate care, transforming lives through confidence-boosting hair solutions refined over 30 years. North Carolina, United States, June 6, 2025 -- Dr. Arthur Zacco, the driving force behind AZ Hair Restoration in Raleigh, North Carolina, marks 30 years at the forefront of hair transplantation. His three-decade career has been defined by precision, dedication, and a deep understanding of the transformative power of hair restoration. Dr. Zacco's work has touched thousands of lives, providing solutions for hair loss that restore not just hair, but also the confidence and self-assurance that come with it. Graduated with a solid foundation in biology and chemistry from the University of Central Florida and received his medical degree from A.T. Still University, Dr. Zacco has combined his scientific background with an artistic eye. Over the years, he has honed his techniques to produce natural-looking and long-lasting results, free from the tell-tale signs of surgery that once plagued the field of hair restoration. 'My goal is to ensure that patients achieve natural and long-lasting results that restore their hair and self-esteem,' says Dr. Zacco. Hair loss has far-reaching implications, affecting not only appearance but also personal and social interactions. Dr. Zacco's methods have provided relief to patients experiencing the distress of thinning hair, baldness, or receding hairlines. His approach, centered on a deep understanding of each patient's unique needs, employs a combination of Follicular Unit Transplantation (FUT), Follicular Unit Extraction (FUE), and Multiple Follicular Unit (MFU) grafting to create seamless, natural results. 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About AZ Hair Restoration AZ Hair Restoration, founded by Dr. Arthur Zacco, is a premier hair restoration clinic based in Raleigh, North Carolina. With over 30 years of experience in the field, Dr. Zacco has earned a reputation for providing personalized care and natural-looking results through a range of advanced techniques, including Follicular Unit Transplantation (FUT), Follicular Unit Extraction (FUE), and Multiple Follicular Unit (MFU) grafting. The clinic offers comprehensive consultations and tailored treatment plans designed to meet each patient's unique hair restoration goals. AZ Hair Restoration is committed to helping patients regain their confidence and improve their quality of life through expert hair transplantation. Contact Info: Name: Dr. Arthur Zacco, Founder Email: Send Email Organization: AZ Hair Restoration Address: Raleigh, North Carolina, USA 27613 Website: Release ID: 89161824 In case of identifying any errors, concerns, or inconsistencies within the content shared in this press release that necessitate action or if you require assistance with a press release takedown, we strongly urge you to notify us promptly by contacting [email protected] (it is important to note that this email is the authorized channel for such matters, sending multiple emails to multiple addresses does not necessarily help expedite your request). Our expert team is committed to addressing your concerns within 8 hours by taking necessary actions diligently to rectify any identified issues or supporting you with the removal process. Delivering accurate and reliable information remains our top priority.

Oncoscope Officially Launches, Ushering in a New Era of Real Time Oncology Intelligence
Oncoscope Officially Launches, Ushering in a New Era of Real Time Oncology Intelligence

Associated Press

timean hour ago

  • Associated Press

Oncoscope Officially Launches, Ushering in a New Era of Real Time Oncology Intelligence

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