Latest news with #AdaptiveBiotechnologies
Business Wire
4 days ago
- Business
- Business Wire
Grindr Appoints Veteran Public Company CFO and Audit Committee Chair Chad Cohen to Board of Directors
WEST HOLLYWOOD, Calif.--(BUSINESS WIRE)--Grindr Inc. (NYSE: GRND), the Global Gayborhood in Your Pocket™, today announced the appointment of Chad Cohen, former Chief Financial Officer of Zillow Group Inc. (Nasdaq: Z) and Adaptive Biotechnologies Corp. (Nasdaq: ADPT) and Founding Partner of Scala Advisors, LLC, to Grindr's Board of Directors as of June 3, 2025. Cohen was also appointed to serve as the Chair of Grindr's Audit Committee. 'We are pleased to welcome Chad to Grindr's Board of Directors,' said Grindr CEO George Arison. 'His broad experience and deep expertise in helping grow successful public companies will be an invaluable asset to Grindr's Board.' A seasoned public company finance executive and board member, Cohen has helped grow several multi-billion dollar technology companies, including multiple leading consumer Internet brands. Prior to his current role, Cohen served as the Chief Financial Officer and Chief Operating Officer for Capella Space, a satellite-based earth observation company; as well as the Chief Financial Officer at Adaptive Biotechnologies, an immune-driven medicine company; and Zillow Group, a leading real-estate marketplace company. During his tenure, Cohen played a pivotal role in leading both Zillow and Adaptive Biotechnologies through their IPOs and scaling both companies through periods of hypergrowth. Additionally, Cohen served as a Board Director and Chair of the audit committee for Vacasa, Inc. (Nasdaq: VCSA), a vacation rental management platform, and for Trupanion, Inc. (Nasdaq: TRUP), a pet insurance company. Cohen was also an Operating Partner at Cota Capital, Assistant Controller at Ticketmaster Entertainment, VP and Assistant Controller at Countrywide Bank, and Supervising Senior Auditor at Ernst & Young. He began his career as a Financial Planning Analyst at Novellus Systems. Today, Cohen serves as Founding Partner and CEO at Scala Advisors, LLC, where he leverages his expertise to advise public and private companies on finance, business operations, and investor relations initiatives. With Cohen's appointment, Director Gary Horowitz stepped down from Grindr's Board. 'We are pleased to welcome Chad to Grindr's Board of Directors,' said Grindr CEO George Arison. 'His broad experience and deep expertise in helping grow successful public companies will be an invaluable asset to Grindr's Board. I look forward to collaborating with Chad as we continue to expand Grindr's capabilities as the Global Gayborhood in Your Pocket. I also want to thank both Gary Horowitz for his dedicated service to Grindr and Nathan Richardson for serving as our Audit Committee Chair during our first three years as a public company, and I'm happy that Nathan is continuing on the Board and the Audit Committee.' 'Grindr has established itself as the premier social platform and market leader in dating apps for the gay community. Its outstanding business performance and strong financial profile is a testament to its leading market position, and I am thrilled to be joining the Board of Directors,' said Cohen. 'I look forward to providing my expertise and support to George and the management team to advance Grindr's mission.' About Grindr With more than 14.5 million average monthly active users, Grindr has grown to become the Global Gayborhood in Your Pocket™, on a mission to make a world where the lives of our global community are free, equal, and just. Available in 190 countries and territories, Grindr is often the primary way for its users to connect, express themselves, and discover the world around them. Since 2015, Grindr for Equality has advanced human rights, health, and safety for millions of LGBTQ+ people in partnership with organizations in every region of the world. Grindr has offices in West Hollywood, the Bay Area, Chicago, and New York. The Grindr app is available on the App Store and Google Play.
Yahoo
28-05-2025
- Business
- Yahoo
Adaptive Biotechnologies to Participate in the Goldman Sachs 46th Annual Global Healthcare Conference
SEATTLE, May 28, 2025 (GLOBE NEWSWIRE) -- Adaptive Biotechnologies Corporation (Nasdaq: ADPT), a commercial stage biotechnology company that aims to translate the genetics of the adaptive immune system into clinical products to diagnose and treat disease, today announced it will be participating in the upcoming Goldman Sachs 46th Annual Global Healthcare Conference in Miami, FL. Adaptive Biotechnologies' management is scheduled to participate in a fireside chat on Wednesday, June 11th at 5:40 a.m. Pacific Time / 8:40 a.m. Eastern Time. Interested parties may access a live and archived webcast of the presentation on the 'Investors' section of the company website at: About Adaptive Biotechnologies Adaptive Biotechnologies ('we' or 'our') is a commercial-stage biotechnology company focused on harnessing the inherent biology of the adaptive immune system to transform the diagnosis and treatment of disease. We believe the adaptive immune system is nature's most finely tuned diagnostic and therapeutic for most diseases, but the inability to decode it has prevented the medical community from fully leveraging its capabilities. Our proprietary immune medicine platform reveals and translates the massive genetics of the adaptive immune system with scale, precision and speed. We apply our platform to partner with biopharmaceutical companies, inform drug development, and develop clinical diagnostics across our two business segments: Minimal Residual Disease (MRD) and Immune Medicine. Our commercial products and clinical pipeline enable the diagnosis, monitoring, and treatment of diseases such as cancer and autoimmune disorders. Our goal is to develop and commercialize immune-driven clinical products tailored to each individual patient. ADAPTIVE INVESTORSKarina Calzadilla, Vice President, Investor Relations and FP&A201-396-1687investors@ ADAPTIVE MEDIAErica Jones, Associate Corporate Communications Director206-279-2423media@ in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Yahoo
04-05-2025
- Business
- Yahoo
Adaptive Biotechnologies Corporation (NASDAQ:ADPT) Released Earnings Last Week And Analysts Lifted Their Price Target To US$10.57
A week ago, Adaptive Biotechnologies Corporation (NASDAQ:ADPT) came out with a strong set of first-quarter numbers that could potentially lead to a re-rate of the stock. Revenue crushed expectations at US$52m, beating expectations by 24%. Adaptive Biotechnologies reported a statutory loss of US$0.20 per share, which - although not amazing - was much smaller than the analysts predicted. The analysts typically update their forecasts at each earnings report, and we can judge from their estimates whether their view of the company has changed or if there are any new concerns to be aware of. We've gathered the most recent statutory forecasts to see whether the analysts have changed their earnings models, following these results. Our free stock report includes 3 warning signs investors should be aware of before investing in Adaptive Biotechnologies. Read for free now. Taking into account the latest results, the consensus forecast from Adaptive Biotechnologies' eight analysts is for revenues of US$216.0m in 2025. This reflects a meaningful 14% improvement in revenue compared to the last 12 months. Losses are expected to be contained, narrowing 11% from last year to US$0.83. Yet prior to the latest earnings, the analysts had been forecasting revenues of US$212.7m and losses of US$0.92 per share in 2025. Although the revenue estimates have not really changed Adaptive Biotechnologies'future looks a little different to the past, with a favorable reduction in the loss per share forecasts in particular. View our latest analysis for Adaptive Biotechnologies The average price target rose 8.8% to US$10.57, with the analysts signalling that the forecast reduction in losses would be a positive for the stock's valuation. There's another way to think about price targets though, and that's to look at the range of price targets put forward by analysts, because a wide range of estimates could suggest a diverse view on possible outcomes for the business. There are some variant perceptions on Adaptive Biotechnologies, with the most bullish analyst valuing it at US$13.00 and the most bearish at US$7.00 per share. These price targets show that analysts do have some differing views on the business, but the estimates do not vary enough to suggest to us that some are betting on wild success or utter failure. One way to get more context on these forecasts is to look at how they compare to both past performance, and how other companies in the same industry are performing. The analysts are definitely expecting Adaptive Biotechnologies' growth to accelerate, with the forecast 19% annualised growth to the end of 2025 ranking favourably alongside historical growth of 13% per annum over the past five years. By contrast, our data suggests that other companies (with analyst coverage) in a similar industry are forecast to grow their revenue at 6.0% per year. Factoring in the forecast acceleration in revenue, it's pretty clear that Adaptive Biotechnologies is expected to grow much faster than its industry. The most important thing to take away is that the analysts reconfirmed their loss per share estimates for next year. Happily, there were no major changes to revenue forecasts, with the business still expected to grow faster than the wider industry. There was also a nice increase in the price target, with the analysts clearly feeling that the intrinsic value of the business is improving. With that said, the long-term trajectory of the company's earnings is a lot more important than next year. At Simply Wall St, we have a full range of analyst estimates for Adaptive Biotechnologies going out to 2027, and you can see them free on our platform here.. Even so, be aware that Adaptive Biotechnologies is showing 3 warning signs in our investment analysis , you should know about... Have feedback on this article? Concerned about the content? Get in touch with us directly. Alternatively, email editorial-team (at) article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned. Sign in to access your portfolio
Yahoo
13-02-2025
- Business
- Yahoo
Adaptive Biotechnologies Full Year 2024 Earnings: EPS Beats Expectations
Revenue: US$179.0m (up 5.1% from FY 2023). Net loss: US$159.5m (loss narrowed by 29% from FY 2023). US$1.08 loss per share (improved from US$1.56 loss in FY 2023). All figures shown in the chart above are for the trailing 12 month (TTM) period Revenue was in line with analyst estimates. Earnings per share (EPS) surpassed analyst estimates by 3.2%. Looking ahead, revenue is forecast to grow 18% p.a. on average during the next 3 years, compared to a 6.0% growth forecast for the Life Sciences industry in the US. Performance of the American Life Sciences industry. The company's shares are down 6.2% from a week ago. It is worth noting though that we have found 2 warning signs for Adaptive Biotechnologies that you need to take into consideration. Have feedback on this article? Concerned about the content? Get in touch with us directly. Alternatively, email editorial-team (at) article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned. Sign in to access your portfolio
Yahoo
11-02-2025
- Business
- Yahoo
Adaptive Biotechnologies Reports Fourth Quarter and Full Year 2024 Financial Results
SEATTLE, Feb. 11, 2025 (GLOBE NEWSWIRE) -- Adaptive Biotechnologies Corporation ('Adaptive Biotechnologies') (Nasdaq: ADPT), a commercial stage biotechnology company that aims to translate the genetics of the adaptive immune system into clinical products to diagnose and treat disease, today reported financial results for the fourth quarter and full year ended December 31, 2024. '2024 was a year of strong execution, marked by key catalysts achieved in our MRD business and advancements in our Immune Medicine programs. Our MRD revenue grew by 42%, with a 35% increase in clonoSEQ test volume, and we nominated a lead autoimmune indication within our Immune Medicine business,' said Chad Robins, chief executive officer and co-founder of Adaptive Biotechnologies. 'With strong momentum heading into 2025, we are focused on achieving profitability in MRD, advancing our therapeutics pipeline in Immune Medicine, and maintaining a durable cash position to support sustainable, long-term growth.' Recent Highlights Revenue for the fourth quarter and full year 2024 was $47.5 million and $179.0 million, respectively. The MRD business, which contributed 85% of revenue in the fourth quarter and 81% of revenue in the full year, grew 31% and 42% over the corresponding periods a year ago. clonoSEQ® test volume increased 34% to 20,945 tests delivered in the fourth quarter of 2024, compared to the fourth quarter 2023 and ended the year with 76,105 tests delivered, up 35% versus 2023. Obtained updated Medicare Clinical Laboratory Fee Schedule (CLFS) Gapfill Determination for clonoSEQ of $2,007 per test, a 17% increase from the previous implied rate under the episode structure. The FDA's Oncologic Drug Advisory Committee (ODAC) voted unanimously in favor of the use of MRD as a primary endpoint to support the accelerated approval of new therapies for patients with multiple myeloma. Received expanded Medicare coverage of clonoSEQ for assessing measurable residual disease in Mantle Cell Lymphoma (MCL), enabling initiation of MCL promotional efforts. Signed an exclusive strategic commercial partnership with NeoGenomics to cross-promote our clonoSEQ® test along with NeoGenomics' COMPASS® and CHART® hematopathology services. Completed multiple antibody mouse immunization campaigns in prioritized autoimmune indications and functionally tested a subset of selected antibodies to a number of disease-causing targets in these indications. Nominated a lead autoimmune indication to further advance on the preclinical development of antibody therapeutic candidates in this first autoimmune indication. Fourth Quarter 2024 Financial Results Revenue was $47.5 million for the quarter ended December 31, 2024, representing a 4% increase from the fourth quarter in the prior year. MRD revenue was $40.1 million for the quarter, representing a 31% increase from the fourth quarter in the prior year. Immune Medicine revenue was $7.3 million for the quarter, representing a 51% decrease from the fourth quarter in the prior year. Operating expenses for the fourth quarter of 2024 were $81.3 million, compared to $116.9 million in the fourth quarter of the prior year, which included a $25.4 million lease impairment charge, representing a decrease of 30%. Excluding the impact of the lease impairment charge, operating expenses for the fourth quarter of 2024 decreased 11% compared to the fourth quarter of the prior year. Interest and other income, net was $3.1 million for the fourth quarter of 2024, compared to $4.6 million in the fourth quarter of the prior year. Interest expense from our revenue interest purchase agreement was $3.0 million in both the fourth quarter of 2024 and the fourth quarter of the prior year. Net loss was $33.7 million for the fourth quarter of 2024, compared to $69.5 million for the same period in 2023. Adjusted EBITDA (non-GAAP) was a loss of $16.4 million for the fourth quarter of 2024, compared to a loss of $24.7 million for the fourth quarter of the prior year. Full Year 2024 Financial Results Revenue was $179.0 million for the year ended December 31, 2024, representing a 5% increase from the prior year. MRD revenue was $145.5 million in 2024, representing a 42% increase from the prior year. Immune Medicine revenue was $33.4 million in 2024, representing a 51% decrease from 2023. Operating expenses for 2024, which included restructuring and long-lived asset impairment charges of $9.2 million, were $341.5 million, compared to $397.3 million for 2023, which included a $25.4 million lease impairment charge, representing a decrease of 14%. Excluding the impact of restructuring and impairment charges, operating expenses for 2024 decreased 11% compared to the prior year. Interest and other income, net was $14.5 million in 2024, compared to $15.5 million in 2023. Interest expense from our revenue interest purchase agreement was $11.6 million in 2024, compared to $13.8 million in 2023. Net loss was $159.6 million in 2024, compared to $225.3 million in 2023. Adjusted EBITDA (non-GAAP) was a loss of $80.4 million for 2024, compared to a loss of $116.4 million in the prior year. Cash, cash equivalents and marketable securities was $256.0 million as of December 31, 2024. 2025 Financial Guidance Adaptive Biotechnologies expects full year revenue for the MRD business to be between $175 million and $185 million. No revenue guidance is provided for the Immune Medicine business. We expect full year total company operating expenses, including cost of revenue, to be between $340 million and $350 million. We expect full year total company cash burn to be between $60 million and $70 million. Management will provide further details on the outlook during the conference call. Webcast and Conference Call Information Adaptive Biotechnologies will host a conference call to discuss its fourth quarter and full year 2024 financial results after market close on Tuesday, February 11, 2025 at 4:30 PM Eastern Time. The conference call can be accessed at The webcast will be archived and available for replay at least 90 days after the event. About Adaptive Biotechnologies Adaptive Biotechnologies ('we' or 'our') is a commercial-stage biotechnology company focused on harnessing the inherent biology of the adaptive immune system to transform the diagnosis and treatment of disease. We believe the adaptive immune system is nature's most finely tuned diagnostic and therapeutic for most diseases, but the inability to decode it has prevented the medical community from fully leveraging its capabilities. Our proprietary immune medicine platform reveals and translates the massive genetics of the adaptive immune system with scale, precision and speed. We apply our platform to partner with biopharmaceutical companies, inform drug development, and develop clinical diagnostics across our two business segments: Minimal Residual Disease (MRD) and Immune Medicine. Our commercial products and clinical pipeline enable the diagnosis, monitoring, and treatment of diseases such as cancer and autoimmune disorders. Our goal is to develop and commercialize immune-driven clinical products tailored to each individual patient. Forward-Looking Statements This press release contains forward-looking statements that are based on management's beliefs and assumptions and on information currently available to management. All statements contained in this release other than statements of historical fact are forward-looking statements, including statements regarding our ability to develop, commercialize and achieve market acceptance of our current and planned products and services, our research and development efforts and other matters regarding our business strategies, use of capital, results of operations and financial position and plans and objectives for future operations. In some cases, you can identify forward-looking statements by the words 'may,' 'will,' 'could,' 'would,' 'should,' 'expect,' 'intend,' 'plan,' 'anticipate,' 'believe,' 'estimate,' 'predict,' 'project,' 'potential,' 'continue,' 'ongoing' or the negative of these terms or other comparable terminology, although not all forward-looking statements contain these words. These statements involve risks, uncertainties and other factors that may cause actual results, levels of activity, performance or achievements to be materially different from the information expressed or implied by these forward-looking statements. These risks, uncertainties and other factors are described under "Risk Factors," "Management's Discussion and Analysis of Financial Condition and Results of Operations" and elsewhere in the documents we file with the Securities and Exchange Commission from time to time. We caution you that forward-looking statements are based on a combination of facts and factors currently known by us and our projections of the future, about which we cannot be certain. As a result, the forward-looking statements may not prove to be accurate. The forward-looking statements in this press release represent our views as of the date hereof. We undertake no obligation to update any forward-looking statements for any reason, except as required by law. Use of Non-GAAP Financial Measure To supplement our unaudited consolidated statements of operations and unaudited consolidated balance sheets, which are prepared in conformity with generally accepted accounting principles in the United States of America ('GAAP'), this press release also includes references to Adjusted EBITDA, which is a non-GAAP financial measure that we define as net loss attributable to Adaptive Biotechnologies Corporation adjusted for interest and other income, net, interest expense, income tax (expense) benefit, depreciation and amortization expense, impairment costs for long-lived assets, restructuring expense and share-based compensation expense. We define our segment Adjusted EBITDA in the same way to the extent the net loss attributable to Adaptive Biotechnologies Corporation and adjustments are allocable to each segment. We have provided reconciliations of net loss attributable to Adaptive Biotechnologies Corporation, the most directly comparable GAAP financial measure, to Adjusted EBITDA at the end of this press release. Management uses Adjusted EBITDA, including segment Adjusted EBITDA, to evaluate the financial performance of our business and segments and to evaluate the effectiveness of our strategies. We present these figures because we believe it is frequently used by analysts, investors and other interested parties to evaluate companies in our industry and it facilitates comparisons on a consistent basis across reporting periods. Further, we believe it is helpful in highlighting trends in our operating results because it excludes items that are not indicative of our core operating performance. Adjusted EBITDA, including segment Adjusted EBITDA, has limitations as an analytical tool and you should not consider it in isolation or as a substitute for analysis of our results as reported under GAAP. We may in the future incur expenses similar to the adjustments we make. In particular, we expect to incur meaningful share-based compensation expense in the future. Other limitations include that Adjusted EBITDA, including segment Adjusted EBITDA, does not reflect: all expenditures or future requirements for capital expenditures or contractual commitments; changes in our working capital needs; interest expense, which is an ongoing element of our costs to operate; income tax (expense) benefit, which may be a necessary element of our costs and ability to operate; the costs of replacing the assets being depreciated and amortized, which will often have to be replaced in the future; the noncash component of employee compensation expense; long-lived assets impairment costs; and the impact of earnings or charges resulting from matters we consider not to be reflective, on a recurring basis, of our ongoing operations, such as our restructuring activities and reductions in workforce. In addition, Adjusted EBITDA may not be comparable to similarly titled measures used by other companies in our industry or across different industries. ADAPTIVE INVESTORSKarina Calzadilla, Vice President, Investor Relations201-396-1687investors@ ADAPTIVE MEDIAErica Jones, Associate Corporate Communications Director206-279-2423media@ Adaptive BiotechnologiesConsolidated Statements of Operations(in thousands, except share and per share amounts)(unaudited) Three Months EndedDecember 31, Year EndedDecember 31, 2024 2023 2024 2023 Revenue $ 47,459 $ 45,784 $ 178,957 $ 170,276 Operating expenses Cost of revenue 18,045 19,616 72,080 75,553 Research and development 23,192 28,746 102,953 122,117 Sales and marketing 21,575 21,906 84,759 88,579 General and administrative 18,056 20,726 72,806 83,934 Amortization of intangible assets 428 429 1,703 1,699 Impairment of long-lived assets — 25,429 7,205 25,429 Total operating expenses 81,296 116,852 341,506 397,311 Loss from operations (33,837 ) (71,068 ) (162,549 ) (227,035 ) Interest and other income, net 3,072 4,613 14,534 15,531 Interest expense (2,952 ) (3,012 ) (11,580 ) (13,800 ) Net loss (33,717 ) (69,467 ) (159,595 ) (225,304 ) Add: Net loss attributable to noncontrolling interest 25 26 103 54 Net loss attributable to Adaptive Biotechnologies Corporation $ (33,692 ) $ (69,441 ) $ (159,492 ) $ (225,250 ) Net loss per share attributable to Adaptive Biotechnologies Corporation common shareholders, basic and diluted $ (0.23 ) $ (0.48 ) $ (1.08 ) $ (1.56 ) Weighted-average shares used in computing net loss per share attributable to Adaptive Biotechnologies Corporation common shareholders, basic and diluted 147,677,685 144,900,669 147,101,648 144,383,294 Adaptive BiotechnologiesConsolidated Balance Sheets(in thousands, except share and per share amounts)(unaudited) December 31, 2024 2023 Assets Current assets Cash and cash equivalents $ 47,920 $ 65,064 Short-term marketable securities (amortized cost of $174,186 and $281,122, respectively) 174,374 281,337 Accounts receivable, net 41,731 37,969 Inventory 8,440 14,448 Prepaid expenses and other current assets 11,287 11,370 Total current assets 283,752 410,188 Long-term assets Property and equipment, net 48,616 68,227 Operating lease right-of-use assets 45,767 52,096 Long-term marketable securities (amortized cost of $33,682) 33,660 — Restricted cash 2,897 2,932 Intangible assets, net 3,425 5,128 Goodwill 118,972 118,972 Other assets 2,287 3,591 Total assets $ 539,376 $ 661,134 Liabilities and shareholders' equity Current liabilities Accounts payable $ 7,265 $ 7,719 Accrued liabilities 8,157 8,597 Accrued compensation and benefits 15,838 13,685 Current portion of operating lease liabilities 10,239 9,384 Current portion of deferred revenue 55,689 48,630 Current portion of revenue interest liability, net 865 — Total current liabilities 98,053 88,015 Long-term liabilities Operating lease liabilities, less current portion 79,148 89,388 Deferred revenue, less current portion 27,256 44,793 Revenue interest liability, net, less current portion 132,414 130,660 Other long-term liabilities 20 — Total liabilities 336,891 352,856 Commitments and contingencies Shareholders' equity Preferred stock: $0.0001 par value, 10,000,000 shares authorized at December 31, 2024 and 2023; no shares issued and outstanding at December 31, 2024 and 2023 — — Common stock: $0.0001 par value, 340,000,000 shares authorized at December 31, 2024 and 2023; 147,773,744 and 145,082,271 shares issued and outstanding at December 31, 2024 and 2023, respectively 14 14 Additional paid-in capital 1,506,353 1,452,502 Accumulated other comprehensive gain 166 215 Accumulated deficit (1,303,824 ) (1,144,332 ) Total Adaptive Biotechnologies Corporation shareholders' equity 202,709 308,399 Noncontrolling interest (224 ) (121 ) Total shareholders' equity 202,485 308,278 Total liabilities and shareholders' equity $ 539,376 $ 661,134 Adjusted EBITDA The following is a reconciliation of net loss attributable to Adaptive Biotechnologies Corporation, the most directly comparable GAAP financial measure, to Adjusted EBITDA for the periods presented (in thousands, unaudited): Three Months EndedDecember 31, Year EndedDecember 31, 2024 2023 2024 2023 Net loss attributable to Adaptive Biotechnologies Corporation $ (33,692 ) $ (69,441 ) $ (159,492 ) $ (225,250 ) Interest and other income, net (3,072 ) (4,613 ) (14,534 ) (15,531 ) Interest expense 2,952 3,012 11,580 13,800 Depreciation and amortization expense 4,448 5,392 19,256 22,231 Impairment of long-lived assets — 25,429 7,205 25,429 Restructuring expense 87 — 2,004 — Share-based compensation expense 12,832 15,556 53,610 62,908 Adjusted EBITDA $ (16,445 ) $ (24,665 ) $ (80,371 ) $ (116,413 ) Segment Information (Including Segment Adjusted EBITDA) The following tables set forth segment information for the periods presented (in thousands, unaudited): Three Months Ended December 31, 2024 MRD Immune Medicine Unallocated Corporate Total Revenue $ 40,149 $ 7,310 $ — $ 47,459 Operating expenses 54,979 20,389 5,928 81,296 Adjusted EBITDA (6,555 ) (6,833 ) (3,057 ) (16,445 ) Reconciliation of Net Loss to Adjusted EBITDA: Net loss $ (14,830 ) $ (13,079 ) $ (5,808 ) $ (33,717 ) Net loss attributable to noncontrolling interest — — 25 25 Net loss attributable to Adaptive Biotechnologies Corporation (14,830 ) (13,079 ) (5,783 ) (33,692 ) Interest and other income, net — — (3,072 ) (3,072 ) Interest expense — — 2,952 2,952 Depreciation and amortization expense 2,340 1,673 435 4,448 Restructuring expense 77 10 — 87 Share-based compensation expense 5,858 4,563 2,411 12,832 Adjusted EBITDA $ (6,555 ) $ (6,833 ) $ (3,057 ) $ (16,445 ) Three Months Ended December 31, 2023 MRD Immune Medicine Unallocated Corporate Total Revenue $ 30,762 $ 15,022 $ — $ 45,784 Operating expenses 58,183 26,280 32,389 116,852 Adjusted EBITDA (17,763 ) (2,979 ) (3,923 ) (24,665 ) Reconciliation of Net Loss to Adjusted EBITDA: Net loss $ (27,421 ) $ (11,258 ) $ (30,788 ) $ (69,467 ) Net loss attributable to noncontrolling interest — — 26 26 Net loss attributable to Adaptive Biotechnologies Corporation (27,421 ) (11,258 ) (30,762 ) (69,441 ) Interest and other income, net — — (4,613 ) (4,613 ) Interest expense — — 3,012 3,012 Depreciation and amortization expense 2,413 2,529 450 5,392 Impairment of right-of-use and related long-lived assets — — 25,429 25,429 Share-based compensation expense 7,245 5,750 2,561 15,556 Adjusted EBITDA $ (17,763 ) $ (2,979 ) $ (3,923 ) $ (24,665 ) Year Ended December 31, 2024 MRD Immune Medicine Unallocated Corporate Total Revenue $ 145,529 $ 33,428 $ — $ 178,957 Operating expenses 225,764 91,052 24,690 341,506 Adjusted EBITDA (41,223 ) (26,005 ) (13,143 ) (80,371 ) Reconciliation of Net Loss to Adjusted EBITDA: Net loss $ (80,235 ) $ (57,624 ) $ (21,736 ) $ (159,595 ) Net loss attributable to noncontrolling interest — — 103 103 Net loss attributable to Adaptive Biotechnologies Corporation (80,235 ) (57,624 ) (21,633 ) (159,492 ) Interest and other income, net — — (14,534 ) (14,534 ) Interest expense — — 11,580 11,580 Depreciation and amortization expense 10,073 7,450 1,733 19,256 Impairment of long-lived assets 2,819 4,386 — 7,205 Restructuring expense 1,272 732 — 2,004 Share-based compensation expense 24,848 19,051 9,711 53,610 Adjusted EBITDA $ (41,223 ) $ (26,005 ) $ (13,143 ) $ (80,371 ) Year Ended December 31, 2023 MRD Immune Medicine Unallocated Corporate Total Revenue $ 102,739 $ 67,537 $ — $ 170,276 Operating expenses 229,129 115,031 53,151 397,311 Adjusted EBITDA (88,844 ) (14,128 ) (13,441 ) (116,413 ) Reconciliation of Net Loss to Adjusted EBITDA: Net loss $ (126,390 ) $ (47,494 ) $ (51,420 ) $ (225,304 ) Net loss attributable to noncontrolling interest — — 54 54 Net loss attributable to Adaptive Biotechnologies Corporation (126,390 ) (47,494 ) (51,366 ) (225,250 ) Interest and other income, net — — (15,531 ) (15,531 ) Interest expense — — 13,800 13,800 Depreciation and amortization expense 9,225 10,436 2,570 22,231 Impairment of right-of-use and related long-lived assets — — 25,429 25,429 Share-based compensation expense 28,321 22,930 11,657 62,908 Adjusted EBITDA $ (88,844 ) $ (14,128 ) $ (13,441 ) $ (116,413 )
