Latest news with #AgenusInc
Business Wire
6 days ago
- Business
- Business Wire
Agenus to Highlight Emerging Survival Plateaus with Botensilimab/Balstilimab in Oral Presentation of Study in Refractory Patients Across Five Tumor Types at ESMO 2025
LEXINGTON, Mass.--(BUSINESS WIRE)--Agenus Inc. (Nasdaq: AGEN), a leader in immuno-oncology, today announced that four abstracts highlighting clinical progress across its botensilimab and balstilimab immunotherapy programs have been accepted for presentation at the European Society for Medical Oncology (ESMO) Congress 2025, taking place in Berlin, Germany from October 17-21. The highlight is an oral presentation that will feature emerging survival plateaus from a study of botensilimab plus balstilimab in 343 evaluable patients with refractory metastatic solid tumors across five tumor types. Three additional poster presentations will feature data from investigator-sponsored studies in cervical cancer, MSS metastatic colorectal cancer (mCRC), and non-melanoma skin cancers, underscoring the broad potential of botensilimab and balstilimab based combinations in difficult-to-treat cancers. Presentation Details: 1. Oral Presentation Title: Emerging survival plateaus with botensilimab and balstilimab: Pan tumor data from a large phase 1b trial of advanced solid tumors Presenting Author: Dr. Michael Gordon; HonorHealth Research Institute-AZ, USA Mini Oral Session: Investigational Immunotherapy Session Date: Session Time: 2:00-3:00 PM CEST / 8:00-9:30 AM EDT Location: Hall 5.2 Abstract Number: 3220 2. Poster Presentation Title: Efficacy and safety of balstilimab with or without zalifrelimab in recurrent cervical cancer: Results from the global phase 2 RaPiDs trial Presenting Author: Dr. David O'Malley; The Ohio State University Comprehensive Cancer Center- OH, USA Session Date: Saturday, October 18, 2025 Session Time: 12:00-12:45 PM CEST / 6:00-6:45 AM EDT Location: Hall 25 Abstract Number: 2952 Poster Number: 1164P 3. Presentation Title: A Phase I trial of botensilimab, balstilimab and regorafenib (BBR) in chemotherapy-resistant patients with microsatellite stable (MSS) metastatic colorectal cancer Presenting Author: Dr. Marwan Fakih; City of Hope- CA, USA Session Date: Sunday, October 19, 2025 Session Time: 12:00-12:45 PM CEST / 6:00-6:45 AM EDT Location: Hall 25 Abstract Number: 6197 Poster Number: 851P 4. Presentation Title: A phase 2, open label study to evaluate the safety and clinical activity of balstilimab in patients with advanced/metastatic non-melanoma skin cancers (AGENONMELA) Presenting Author: Dr. Iwona Lugowska; Maria Sklodowska-Curie National Research Institute and Oncology Center - Poland Session Date: Monday, October 20, 2025 Session Time: 12:00-12:45 PM CEST / 6:00-6:45 AM EDT Location: Hall 25 Abstract Number: 7273 Poster Number: 1662P Expand About Agenus Agenus is a leading immuno-oncology company targeting cancer with a comprehensive pipeline of immunological agents. The company was founded in 1994 with a mission to expand patient populations benefiting from cancer immunotherapy through combination approaches, using a broad repertoire of antibody therapeutics, adoptive cell therapies (through MiNK Therapeutics) and adjuvants (through SaponiQx). Agenus has robust end-to-end development capabilities, across commercial and clinical cGMP manufacturing facilities, research and discovery, and a global clinical operations footprint. Agenus is headquartered in Lexington, MA. For more information, visit or @agenus_bio. Information that may be important to investors will be routinely posted on our website and social media channels. About Botensilimab (BOT) Botensilimab is a multifunctional, human Fc enhanced CTLA-4 blocking antibody designed to boost both innate and adaptive anti-tumor immune responses. Its novel design leverages mechanisms of action to extend immunotherapy benefits to 'cold' tumors which generally respond poorly to standard of care or are refractory to conventional PD-1/CTLA-4 therapies and investigational therapies. Botensilimab augments immune responses across a wide range of tumor types by priming and activating T cells, downregulating intratumoral regulatory T cells, activating myeloid cells and inducing long-term memory responses. Botensilimab alone, or in combination with Agenus' investigational PD-1 antibody, balstilimab, has shown clinical responses across nine metastatic, late-line cancers. Approximately 1,200 patients have been treated across the botensilimab/balstilimab program in phase 1 and phase 2 clinical trials. For more information about botensilimab trials, visit About Balstilimab (BAL) Balstilimab is a novel, fully human monoclonal immunoglobulin G4 (IgG4) designed to block PD-1 (programmed cell death protein 1) from interacting with its ligands PD-L1 and PD-L2. It has been evaluated in >900 patients to date and has demonstrated clinical activity and a favorable tolerability profile in several tumor types. Forward-Looking Statements This press release contains forward-looking statements that are made pursuant to the safe harbor provisions of the federal securities laws, including statements regarding its botensilimab and balstilimab programs, expected regulatory timelines and filings, and any other statements containing the words "may," "believes," "expects," "anticipates," "hopes," "intends," "plans," "forecasts," "estimates," "will," 'establish,' 'potential,' 'superiority,' 'best in class,' and similar expressions are intended to identify forward-looking statements. These forward-looking statements are subject to risks and uncertainties that could cause actual results to differ materially. These risks and uncertainties include, among others, the factors described under the Risk Factors section of our most recent Annual Report on Form 10-K for 2024, and subsequent Quarterly Reports on Form 10-Q filed with the Securities and Exchange Commission. Agenus cautions investors not to place considerable reliance on the forward-looking statements contained in this release. These statements speak only as of the date of this press release, and Agenus undertakes no obligation to update or revise the statements, other than to the extent required by law. All forward-looking statements are expressly qualified in their entirety by this cautionary statement. Expand
Yahoo
16-06-2025
- Business
- Yahoo
Agenus Inc. (AGEN) Surges After Zydus Agreement, Analysts Upbeat on Stock
Agenus Inc. (NASDAQ:AGEN) is among the 10 Most Undervalued Stocks to Buy for Under $5. Despite a 39% surge over the past month, it is still a bargain stock, considering its low forward price-earnings ratio. A research doctor, looking intently at their microscope as they try to decipher the mysteries of immuno-oncology. The company's shares have soared on the back of notable recent developments. On June 3, Agenus Inc. (NASDAQ:AGEN) announced that it had signed agreements worth $141 million with Zydus Lifesciences Ltd. and its subsidiaries to accelerate the clinical development of botensilimab and balstilimab (BOT/BAL). Under the agreement, Agenus Inc. (NASDAQ:AGEN) will receive $75 million upfront for the transfer of two manufacturing assets in California. The company will also get an additional $50 million in contingent payments triggered by BOT/BAL production orders. Moreover, it will grant Zydus a license to develop and commercialize BOT and BAL in India and Sri Lanka, with a 5% royalty on net sales to be paid to Agenus. Following the development, analysts at H.C. Wainwright upgraded Agenus Inc. (NASDAQ:AGEN)'s rating from Neutral to Buy, whereas Baird lifted the stock's price target to $6 from $4, while maintaining a Neutral rating for its shares. Investor sentiment in Agenus Inc. (NASDAQ:AGEN) has also been strengthened by recent quarter results, in which the company managed to significantly lower its loss per share to $1.03 from $3.04 in the prior year. While we acknowledge the potential of AGEN as an investment, we believe certain AI stocks offer greater upside potential and carry less downside risk. If you're looking for an extremely undervalued AI stock that also stands to benefit significantly from Trump-era tariffs and the onshoring trend, see our free report on the best short-term AI stock. READ NEXT: The Best and Worst Dow Stocks for the Next 12 Months and 10 Unstoppable Stocks That Could Double Your Money. Disclosure: None. Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Yahoo
16-06-2025
- Business
- Yahoo
Agenus Inc. (AGEN) Surges After Zydus Agreement, Analysts Upbeat on Stock
Agenus Inc. (NASDAQ:AGEN) is among the 10 Most Undervalued Stocks to Buy for Under $5. Despite a 39% surge over the past month, it is still a bargain stock, considering its low forward price-earnings ratio. A research doctor, looking intently at their microscope as they try to decipher the mysteries of immuno-oncology. The company's shares have soared on the back of notable recent developments. On June 3, Agenus Inc. (NASDAQ:AGEN) announced that it had signed agreements worth $141 million with Zydus Lifesciences Ltd. and its subsidiaries to accelerate the clinical development of botensilimab and balstilimab (BOT/BAL). Under the agreement, Agenus Inc. (NASDAQ:AGEN) will receive $75 million upfront for the transfer of two manufacturing assets in California. The company will also get an additional $50 million in contingent payments triggered by BOT/BAL production orders. Moreover, it will grant Zydus a license to develop and commercialize BOT and BAL in India and Sri Lanka, with a 5% royalty on net sales to be paid to Agenus. Following the development, analysts at H.C. Wainwright upgraded Agenus Inc. (NASDAQ:AGEN)'s rating from Neutral to Buy, whereas Baird lifted the stock's price target to $6 from $4, while maintaining a Neutral rating for its shares. Investor sentiment in Agenus Inc. (NASDAQ:AGEN) has also been strengthened by recent quarter results, in which the company managed to significantly lower its loss per share to $1.03 from $3.04 in the prior year. While we acknowledge the potential of AGEN as an investment, we believe certain AI stocks offer greater upside potential and carry less downside risk. If you're looking for an extremely undervalued AI stock that also stands to benefit significantly from Trump-era tariffs and the onshoring trend, see our free report on the best short-term AI stock. READ NEXT: The Best and Worst Dow Stocks for the Next 12 Months and 10 Unstoppable Stocks That Could Double Your Money. Disclosure: None. Sign in to access your portfolio
Business Wire
10-06-2025
- Business
- Business Wire
Agenus Announces Virtual Annual Shareholders Meeting
LEXINGTON, Mass.--(BUSINESS WIRE)--Agenus Inc. ('Agenus') (NASDAQ: AGEN), a leader in immuno-oncology innovation, today announced that its Annual Shareholders Meeting will begin at 10:30 a.m. ET on June 17, 2025, and will be conducted in a virtual format only. Registration for attendees will start at 10:15 a.m. ET. To participate in the Annual Shareholders Meeting, shareholders should visit and enter the 16-digit control number found in their proxy materials. Guests may also access the Annual Shareholders Meeting, but in listen-only mode. No control number is required for guests. Webcast Information: Time: 10:30 a.m. ET A live webcast and replay will be accessible on the Company's website at and at Voting Information: Shareholders of Agenus as of the April 24th, 2025, record date can vote. Alliance Advisors, Agenus's proxy solicitor, can assist shareholders with voting at 844-202-6561 or AGEN@ About Agenus Agenus is a leading immuno-oncology company targeting cancer with a comprehensive pipeline of immunological agents. The company was founded in 1994 with a mission to expand patient populations benefiting from cancer immunotherapy through combination approaches, using a broad repertoire of antibody therapeutics, adoptive cell therapies (through MiNK Therapeutics) and adjuvants (through SaponiQx). Agenus has robust end-to-end development capabilities, across commercial and clinical cGMP manufacturing facilities, research and discovery, and a global clinical operations footprint. Agenus is headquartered in Lexington, MA. For more information, visit or @agenus_bio. Information that may be important to investors will be routinely posted on our website and social media channels.
Yahoo
10-06-2025
- Business
- Yahoo
Agenus Announces Virtual Annual Shareholders Meeting
LEXINGTON, Mass., June 10, 2025--(BUSINESS WIRE)--Agenus Inc. ("Agenus") (NASDAQ: AGEN), a leader in immuno-oncology innovation, today announced that its Annual Shareholders Meeting will begin at 10:30 a.m. ET on June 17, 2025, and will be conducted in a virtual format only. Registration for attendees will start at 10:15 a.m. ET. To participate in the Annual Shareholders Meeting, shareholders should visit and enter the 16-digit control number found in their proxy materials. Guests may also access the Annual Shareholders Meeting, but in listen-only mode. No control number is required for guests. Webcast Information: Date: Tuesday, June 17, 2025 Time: 10:30 a.m. ET A live webcast and replay will be accessible on the Company's website at and at Voting Information: Shareholders of Agenus as of the April 24th, 2025, record date can vote. Alliance Advisors, Agenus's proxy solicitor, can assist shareholders with voting at 844-202-6561 or AGEN@ About Agenus Agenus is a leading immuno-oncology company targeting cancer with a comprehensive pipeline of immunological agents. The company was founded in 1994 with a mission to expand patient populations benefiting from cancer immunotherapy through combination approaches, using a broad repertoire of antibody therapeutics, adoptive cell therapies (through MiNK Therapeutics) and adjuvants (through SaponiQx). Agenus has robust end-to-end development capabilities, across commercial and clinical cGMP manufacturing facilities, research and discovery, and a global clinical operations footprint. Agenus is headquartered in Lexington, MA. For more information, visit or @agenus_bio. Information that may be important to investors will be routinely posted on our website and social media channels. View source version on Contacts Investors 917-362-1370investor@ Media 781-674-4422communications@
